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Lester I. Binder

Northwestern University

77H-index
187Paper Count
2.4WCitation Count
Published Papers 31
Publication Date
Protein homeostasis gene dysregulation in pretangle-bearing nucleus basalis neurons during the progression of Alzheimer's disease
err2016-06-01
err32
errOAAI
errTiernan, Chelsea T.; Ginsberg, Stephen D.; Guillozet-Bongaarts, Angela L.; Ward, Sarah M.; He, Bin; Kanaan, Nicholas M.; Mufson, Elliott J.; Binder, Lester I.; Counts, Scott E.
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Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo
err2015-10-01
err55
PREAI
errViolet, Marie; Chauderlier, Alban; Delattre, Lucie; Tardivel, Meryem; Chouala, Meliza Sendid; Sultan, Audrey; Marciniak, Elodie; Humez, Sandrine; Binder, Lester; Kayed, Rakez; Lefebvre, Bruno; Bonnefoy, Eliette; Buee, Luc; Galas, Marie-Christine
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TOC1: A valuable tool in assessing disease progression in the rTg4510 mouse model of tauopathy
err2014-07-01
err30
errOAAI
errWard, Sarah M.; Himmelstein, Diana S.; Ren, Yan; Fu, Yifan; Yu, Xiao-Wen; Roberts, Kaleigh; Binder, Lester I.; Sahara, Naruhiko
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Tau Oligomers as Potential Targets for Early Diagnosis of Tauopathy
err2014-05-27
err17
PREAI
errSahara, Naruhiko; Ren, Yan; Ward, Sarah; Binder, Lester I.; Suhara, Tetsuya; Higuchi, Makoto
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Proteolytic Cleavage of Polymeric Tau Protein by Caspase-3: Implications for Alzheimer Disease
err2013-12-01
err51
errOAAI
errJarero-Basulto, Jose J.; Luna-Munoz, Jose; Mena, Raul; Kristofikova, Zdena; Ripova, Daniela; Perry, George; Binder, Lester I.; Garcia-Sierra, Francisco
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TOC1: Characterization of a Selective Oligomeric Tau Antibody
err2013-09-24
err65
errOAAI
errWard, Sarah M.; Himmelstein, Diana S.; Lancia, Jody K.; Fu, Yifan; Patterson, Kristina R.; Binder, Lester I.
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Alterations in the Nuclear Architecture Produced by the Overexpression of Tau Protein in Neuroblastoma Cells
err2013-07-09
err23
PREAI
errMonroy-Ramirez, Hugo C.; Basurto-Islas, Gustavo; Mena, Raul; Cisneros, Bulmaro; Binder, Lester I.; Avila, Jesus; Garcia-Sierra, Francisco
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Tau as a therapeutic target in neurodegenerative disease
err2012-10-01
err122
errOAAI
errHimmelstein, Diana S.; Ward, Sarah M.; Lancia, Jody K.; Patterson, Kristina R.; Binder, Lester I.
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Tau oligomers and tau toxicity in neurodegenerative disease
err2012-07-20
err208
errOAAI
errWard, Sarah M.; Himmelstein, Diana S.; Lancia, Jody K.; Binder, Lester I.
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Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport
err2012-04-01
err113
errOAAI
errKanaan, Nicholas M.; Morfini, Gerardo; Pigino, Gustavo; LaPointe, Nichole E.; Andreadis, Athena; Song, Yuyu; Leitman, Ellen; Binder, Lester I.; Brady, Scott T.
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Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody
err2012-03-16
err161
errOAAI
errYoumans, Katherine L.; Tai, Leon M.; Kanekiyo, Takahisa; Stine, W. Blaine, Jr.; Michon, Sara-Claude; Nwabuisi-Heath, Evelyn; Manelli, Arlene M.; Fu, Yifan; Riordan, Sean; Eimer, William A.; Binder, Lester; Bu, Guojun; Yu, Chunjiang; Hartley, Dean M.; LaDu, Mary Jo
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Mild cognitive impairment: pathology and mechanisms
err2011-11-19
err206
errOAAI
errMufson, Elliott J.; Binder, Lester; Counts, Scott E.; DeKosky, Steven T.; deToledo-Morrell, Leyla; Ginsberg, Stephen D.; Ikonomovic, Milos D.; Perez, Sylvia E.; Scheff, Stephen W.
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Selective tau tyrosine nitration in non-AD tauopathies
err2011-11-06
err34
errOAAI
errReyes, Juan F.; Geula, Changiz; Vana, Laurel; Binder, Lester I.
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Ubiquitin is Associated with Early Truncation of Tau Protein at Aspartic Acid421 during the Maturation of Neurofibrillary Tangles in Alzheimer's Disease
err2011-10-12
err31
errOAAI
errGarcia-Sierra, Francisco; Jarero-Basulto, Jose J.; Kristofikova, Zdena; Majer, Emerich; Binder, Lester I.; Ripova, Daniela
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Characterization of Prefibrillar Tau Oligomers in Vitro and in Alzheimer Disease
err2011-07-01
err322
errOAAI
errPatterson, Kristina R.; Remmers, Christine; Fu, Yifan; Brooker, Sarah; Kanaan, Nicholas M.; Vana, Laurel; Ward, Sarah; Reyes, Juan F.; Philibert, Keith; Glucksman, Marc J.; Binder, Lester I.
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A possible link between astrocyte activation and tau nitration in Alzheimer's disease
err2008-08-01
err77
errOAAI
errReyes, Juan F.; Reynolds, Matthew R.; Horowitz, Peleg M.; Fu, Yifan; Guillozet-Bongaarts, Angela L.; Berry, Robert; Binder, Lester I.
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Accumulation of aspartic Acid421- and glutamic Acid391-Cleaved tau in neurofibrillary tangles correlates with progression in Alzheimer disease
err2008-05-01
err141
errOAAI
errBasurto-Islas, Gustavo; Luna-Munoz, Jose; Guillozet-Bongaarts, Angela L.; Binder, Lester I.; Mena, Raul; Garcia-Sierra, Francisco
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Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology
err2007-10-26
err44
PREAI
errMondragon-Rodriguez, S.; Mena, R.; Binder, L. I.; Smith, M. A.; Perry, G.; Garcia-Sierra, F.
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Phosphorylation and cleavage of tau in non-AD tauopathies
err2007-03-15
err63
PREAI
errGuillozet-Bongaarts, Angela L.; Glajch, Kelly E.; Libson, Emilie G.; Cahill, Michael E.; Bigio, Eileen; Berry, Robert W.; Binder, Lester I.
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