Daniel H. Geschwind - Publications, H-index & Citations

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Daniel H. Geschwind

ucla

188H-index

966Paper Count

14.9WCitation Count

Published Papers 385

Publication Date

Acute rapamycin treatment reveals distinct mechanisms of dysfunction in a maternal inflammation mouse model

Nature Communications

IF15.7

2026-07-23

OAAI

JE Le Belle; M. C. Condro; C. Cepeda; KD Oikonomou; K. Tessema; L. Dudley; J. Schoenfield; R. Kawaguchi; D. Geschwind; AJ Silva; Z. Zhang; K. Shokat; NG Harris; HI Kornblum

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A single-cell multiomic analysis identifies molecular and gene-regulatory mechanisms dysregulated in developing Down syndrome neocortex

Science

IF45.8

2026-04-23

PREAI

Celine K. Vuong; Alexis Weber; Patrick Seong; Nana Matoba; Yu-Jen Chen; Jordan Peyer; Shahab Younesi; Angelo Salinda; Daniel Gomez; Gabriella Rivas; Abril Morales; Beck Shafie; Pan Zhang; Susanne Nichterwitz; Le Qi; Nolan T. Fernandez; Emily Friedman; Michael I. Love; Michael J. Gandal; Daniel H. Geschwind; William E. Lowry; Jason L. Stein; Luis de la Torre-Ubieta

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DNA damage burden causes selective CUX2 neuron loss in neuroinflammation

Nature

IF48.5

2026-04-01

OAAI

Laura Morcom; Wenlong Xia; Zhaoyang Xu; Yashika Awasthi; Celine Geywitz; Matthew O. Ellis; Tomas Noli; Amel Zulji; Daniel Yamamoto; Gemma C. Girdler; Li Kai; Keying Zhu; Mingming Wei; Xiao-Yan Tang; Kimberly K. Hoi; Julio Gonzalez-Maya; Greg J. Duncan; Adrien M. Vaquie; Diana Gold Diaz; Riki Kawaguchi; Erdong Liu; Yu Sun; Denny Yang; Gregory D. Jordan; I-Ling Lu; Staffan Holmqvist; Theresa Bartels; Katherine Ridley; Jennifer Ja-Yoon Choi; Santos J. Franco; Eric J. Huang; Ben Emery; Daniel Geschwind; Lucas Schirmer; Gabriel Balmus; Brian Popko; Stephen P. J. Fancy; David H. Rowitch

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Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair

Nature

IF48.5

2026-04-01

OAAI

Wenlong Xia; Laura Morcom; Zhaoyang Xu; I-Ling Lu; Qing Wang; Kimberly K. Hoi; Mingming Wei; Keying Zhu; Gregory Jordan; Xiao-Yan Tang; Julio Gonzalez-Maya; Vanesa S. Mattera; Sophia M. Panigrahi; Riki Kawaguchi; Ben Emery; Santos J. Franco; Daniel H. Geschwind; Brian Popko; David H. Rowitch; Stephen P. J. Fancy

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Developmental convergence and divergence in human stem cell models of autism

Nature

IF48.5

2026-01-29

OAAI

Aaron Gordon; Se-Jin Yoon; Lucy K. Bicks; Jacqueline M. Martín; Greta Pintacuda; Stephanie Arteaga; Brie Wamsley; Qiuyu Guo; Lubayna Elahi; Ricardo E. Dolmetsch; Jonathan A. Bernstein; Ruth O’Hara; Joachim F. Hallmayer; Kasper Lage; Sergiu P. Pasca; Daniel H. Geschwind

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Deletion of murine Sarm1 results in a microenvironment that delays peripheral nerve regeneration after injury

Science Translational Medicine

IF14.6

2025-10-08

PREAI

Ligia B. Schmitd; Hannah Hafner; Ayobami Ward; Elham Asghari Adib; Natalia P. Biscola; Rafi Kohen; Mitre Athaiya; Meghan Tuttle; Manav Patel; Rachel E. Williamson; Emily Desai; Julianna Bennett; Grace Saxman; David Wilborn; Jaisha Shumpert; Xiao-Feng Zhao; Riki Kawaguchi; Daniel H. Geschwind; Ahmet Hoke; Peter Shrager; Catherine A. Collins; Leif A. Havton; Ashley L. Kalinski; Roman J. Giger

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Genetic and structural aspects of amyloid diseases

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2025-10-01

PREAI

Rosenberg, Gregory M.; Murray, Kevin A.; Sawaya, Michael R.; Jiang, Yi Xiao; Geschwind, Daniel H.; Eisenberg, David S.

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Neurodevelopment and neural environment inform Alzheimer's disease age at onset and phenotype

Alzheimer's & Dementia

IF11.1

2025-09-17

OAAI

Zachary A. Miller; Rik Ossenkoppele; Neill R. Graff-Radford; Isabel E. Allen; Wendy Shwe; Lynne Rosenberg; Dustin J. Olguin; Michael G. Erkkinen; P. Monroe Butler; Salvatore Spina; Jennifer S. Yokoyama; Rahul S. Desikan; Philip Scheltens; Wiesje van der Flier; Yolande Pijnenburg; Emma Wolters; Rosa Rademakers; Daniel H. Geschwind; Joel H. Kramer; Howard J. Rosen; Katherine P. Rankin; Lea T. Grinberg; William W. Seeley; Virginia Sturm; David C. Perry; Bruce L. Miller; Gil D. Rabinovici; Maria Luisa Gorno-Tempini

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Correction of sodium channel mutations in sensory neurons reverses aberrant properties

BRAIN

IF11.7

2025-09-01

PREAI

Shim, Jaehoon; Tanaka, Brian; Taub, Daniel G.; Mis, Malgorzata A.; Schulman, Betsy R.; Snavely, Andrew; Cheng, Yung-Chih; Laedermann, Cedric; Buttermore, Elizabeth D.; Ren, Alexander; Hermawan, Crystal; Dou, Dan; Kawaguchi, Riki; Geschwind, Daniel H.; Dib-Hajj, Sulayman; Waxman, Stephen G.; Woolf, Clifford J.

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Author Correction: Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration

Nature Aging

IF19.4

2025-07-07

OAAI

Rowan Saloner; Adam M. Staffaroni; Eric B. Dammer; Erik C. B. Johnson; Emily W. Paolillo; Amy Wise; Hilary W. Heuer; Leah K. Forsberg; Argentina Lario-Lago; Julia D. Webb; Jacob W. Vogel; Alexander F. Santillo; Oskar Hansson; Joel H. Kramer; Bruce L. Miller; Jingyao Li; Joseph Loureiro; Rajeev Sivasankaran; Kathleen A. Worringer; Nicholas T. Seyfried; Jennifer S. Yokoyama; Salvatore Spina; Lea T. Grinberg; William W. Seeley; Lawren VandeVrede; Peter A. Ljubenkov; Ece Bayram; Andrea Bozoki; Danielle Brushaber; Ciaran M. Considine; Gregory S. Day; Bradford C. Dickerson; Kimiko Domoto-Reilly; Kelley Faber; Douglas R. Galasko; Tania Gendron; Daniel H. Geschwind; Nupur Ghoshal; Neill Graff-Radford; Chadwick M. Hales; Lawrence S. Honig; Ging-Yuek R. Hsiung; Edward D. Huey; John Kornak; Walter Kremers; Maria I. Lapid; Suzee E. Lee; Irene Litvan; Corey T. McMillan; Mario F. Mendez; Toji Miyagawa; Alexander Pantelyat; Belen Pascual; Joseph Masdeu; Henry L. Paulson; Leonard Petrucelli; Peter Pressman; Rosa Rademakers; Eliana Marisa Ramos; Katya Rascovsky; Erik D. Roberson; Rodolfo Savica; Allison Snyder; Anna Campbell Sullivan; M. Carmela Tartaglia; Marijne Vandebergh; Brad F. Boeve; Howie J. Rosen; Julio C. Rojas; Adam L. Boxer; Kaitlin B. Casaletto

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m6A deficiency impairs hypothalamic neurogenesis of feeding-related neurons in mice and human and leads to adult in mice

CELL STEM CELL

IF20.4

2025-05-01

PREAI

Shen, Yachen; Wong, Samuel Zheng Hao; Ma, Tong; Zhang, Feng; Wang, Qing; Kawaguchi, Riki; Geschwind, Daniel H.; Wang, Jeremy; He, Chuan; Ming, Guo-li; Song, Hongjun

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Sex differences in clinical phenotypes of behavioral variant frontotemporal dementia

ALZHEIMERS & DEMENTIA

IF11.1

2025-04-25

OAAI

Liu, XL; de Boer, SCM; Cortez, K; Poos, JM; Illán-Gala, I; Heuer, H; Forsberg, LK; Casaletto, K; Memel, M; Appleby, BS; Barmada, S; Bozoki, A; Clark, D; Cobigo, Y; Darby, R; Dickerson, BC; Domoto-Reilly, K; Galasko, DR; Geschwind, DH; Ghoshal, N; Graff-Radford, NR; Grant, IM; Hsiung, GYR; Honig, LS; Huey, ED; Irwin, D; Kantarci, K; Léger, GC; Litvan, I; Mackenzie, IR; Masdeu, JC; Mendez, MF; Onyike, CU; Pascual, B; Pressman, P; Bayram, E; Ramos, EM; Roberson, ED; Rogalski, E; Bouzigues, A; Russell, LL; Foster, PH; Ferry-Bolder, E; Masellis, M; van Swieten, J; Jiskoot, L; Seelaar, H; Sanchez-Valle, R; Laforce, R; Graff, C; Galimberti, D; Vandenberghe, R; de Mendonça, A; Tiraboschi, P; Santana, I; Gerhard, A; Levin, J; Sorbi, S; Otto, M; Pasquier, F; Ducharme, S; Butler, CR; Le Ber, I; Finger, E; Rowe, JB; Synofzik, M; Moreno, F; Borroni, B; Boeve, BF; Boxer, AL; Rosen, HJ; Pijnenburg, YAL; Rohrer, JD; Tartaglia, MC

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Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing

NATURE COMMUNICATIONS

IF15.7

2025-04-25

OAAI

Pottier, Cyril; Kuecuekali, Fahri; Baker, Matt; Batzler, Anthony; Jenkins, Gregory D.; van Blitterswijk, Marka; Vicente, Cristina T.; De Coster, Wouter; Wynants, Sarah; van de Walle, Pieter; Ross, Owen A.; Murray, Melissa E.; Faura, Julia; Haggarty, Stephen J.; van Rooij, Jeroen GJ.; Mol, Merel O.; Hsiung, Ging-Yuek R.; Graff, Caroline; Oeijerstedt, Linn; Neumann, Manuela; Asmann, Yan; Mcdonnell, Shannon K.; Baheti, Saurabh; Josephs, Keith A.; Whitwell, Jennifer L.; Bieniek, Kevin F.; Forsberg, Leah; Heuer, Hilary; Lago, Argentina Lario; Geier, Ethan G.; Yokoyama, Jennifer S.; Oddi, Alexis P.; Flanagan, Margaret; Mao, Qinwen; Hodges, John R.; Kwok, John B.; Domoto-Reilly, Kimiko; Synofzik, Matthis; Wilke, Carlo; Onyike, Chiadi; Dickerson, Bradford C.; Evers, Bret M.; Dugger, Brittany N.; Munoz, David G.; Keith, Julia; Zinman, Lorne; Rogaeva, Ekaterina; Suh, Eunran; Gefen, Tamar; Geula, Changiz; Weintraub, Sandra; Diehl-Schmid, Janine; Farlow, Martin R.; Edbauer, Dieter; Woodruff, Bryan K.; Caselli, Richard J.; Donker Kaat, Laura L.; Huey, Edward D.; Reiman, Eric M.; Mead, Simon; King, Andrew; Roeber, Sigrun; Nana, Alissa L.; Ertekin-Taner, Nilufer; Knopman, David S.; Petersen, Ronald C.; Petrucelli, Leonard; Uitti, Ryan J.; Wszolek, Zbigniew K.; Ramos, Eliana Marisa; Grinberg, Lea T.; Tempini, Maria Luisa Gorno; Rosen, Howard J.; Spina, Salvatore; Piguet, Olivier; Grossman, Murray; Trojanowski, John Q.; Keene, C. Dirk; Jin, Lee-Way; Prudlo, Johannes; Geschwind, Daniel H.; Rissman, Robert A.; Cruchaga, Carlos; Ghetti, Bernardino; Halliday, Glenda M.; Beach, Thomas G.; Serrano, Geidy E.; Arzberger, Thomas; Herms, Jochen; Boxer, Adam L.; Honig, Lawrence S.; Vonsattel, Jean P.; Lopez, Oscar L.; Kofler, Julia; White, Charles L.; Gearing, Marla; Glass, Jonathan; Rohrer, Jonathan D.; Irwin, David J.; Lee, Edward B.; Van Deerlin, Vivianna; Castellani, Rudolph; Mesulam, Marsel M.; Tartaglia, Maria C.; Finger, Elizabeth C.; Troakes, Claire; Al-Sarraj, Safa; Dalgard, Clifton L.; Miller, Bruce L.; Seelaar, Harro; Graff-Radford, Neill R.; Boeve, Bradley F.; Mackenzie, Ian RA.; van Swieten, John C.; Seeley, William W.; Sleegers, Kristel; Dickson, Dennis W.; Biernacka, Joanna M.; Rademakers, Rosa

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Clinical and Imaging Features of Sporadic and Genetic Frontotemporal Lobar Degeneration TDP-43 A and B

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY

IF3.9

2025-03-01

OAAI

Coulborn, Sean; Schafer, Rhiana; Roy, Ashlin R. K.; Sokolowski, Andrzej; Cryns, Noah G.; Leichter, Dana; Lago, Argentina Lario; Ramos, Eliana Marisa; Cobigo, Yann; Spina, Salvatore; Grinberg, Lea T.; Geschwind, Daniel H.; Gorno-Tempini, Maria L.; Kramer, Joel H.; Rosen, Howard J.; Miller, Bruce L.; Seeley, William W.; Perry, David C.

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Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population

MOLECULAR PSYCHIATRY

IF10.1

2025-02-24

OAAI

Gu, Yuanjun; Maria-Stauffer, Eva; Bedford, Saashi A.; Adhya, Deep; Allison, Carrie; Ayeung, Bonnie; Bamford, Rosie; Bethlehem, Richard; Biron-Shental, Tal; Burton, Graham; Davies, Jonathan; Davis, Joanna; Floris, Dori; Franklin, Alice; Gabis, Lidia; Geschwind, Daniel; Greenberg, David M.; Havdahl, Alexandra; Heazell, Alexander; Holt, Rosemary; Hurles, Matthew; Khan, Yumnah; Lai, Meng-Chuan; Lancaster, Madeline; Lombardo, Michael; Martinez, Jose Gonzalez; Mill, Jonathan; Musa, Mahmoud Koko; Niakan, Kathy; Pavlinek, Adam; Polit, Lucia Dutan; Radecki, Marcin; Rowitch, David; Sichlinger, Laura; Srivastava, Deepak; Tsompanidis, Alexandros; Uzefovsky, Florina; Weir, Elizabeth; Zhang, Xinhe; Borglum, Anders; Bybjerg-Grauholm, Jonas; Hougaard, David M.; Mors, Ole; Mortensen, Preben Bo; Nordentoft, Merete; Werge, Thomas; Romero-Garcia, Rafael; Grove, Jakob; Borglum, Anders D.; Martin, Hilary; Baron-Cohen, Simon; Bethlehem, Richard A. I.; Warrier, Varun

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Psychotropic medication usage in sporadic versus genetic behavioral-variant frontotemporal dementia

ALZHEIMERS & DEMENTIA

IF11.1

2024-12-23

OAAI

Vargas-Gonzalez, Juan-Camilo; Dimal, Nico; Cortez, Kasey; Heuer, Hilary; Forsberg, Leah K.; Appleby, Brian S.; Barmada, Sami; Bozoki, Andrea; Clark, David; Cobigo, Yann; Darby, R. Ryan; Dickerson, Bradford C.; Domoto-Reilly, Kimiko; Galasko, Douglas R.; Geschwind, Daniel H.; Ghoshal, Nupur; Graff-Radford, Neill R.; Grant, Ian M.; Irwin, David; Hsiung, Ging-Yuek Robin; Honig, Lawrence S.; Kantarci, Kejal; Leger, Gabriel C.; Litvan, Irene; Mackenzie, Ian R.; Masdeu, Joseph C.; Mendez, Mario F.; Onyike, Chiadi U.; Pascual, Belen; Pressman, Peter; Ramos, Eliana Marisa; Roberson, Erik D.; Rogalski, Emily; Boeve, Brad F.; Boxer, Adam L.; Rosen, Howie J.; Tartaglia, Maria Carmela; ALLFTD Consortium Investigators

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Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection

NATURE AGING

IF19.4

2024-11-14

PREAI

Zhang, Ting; Li, Yunfeng; Pan, Liuliu; Sha, Jihui; Bailey, Michael; Faure-Kumar, Emmanuelle; Williams, Christopher Kazu; Wohlschlegel, James; Magaki, Shino; Niu, Chao; Lee, Yoojin; Su, Yu-Chyuan; Li, Xinmin; Vinters, Harry V.; Geschwind, Daniel H.

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MONOSYNAPTIC TRACING DEFINES BRAIN-WIDE CIRCUIT CONNECTIVITY OF HUMAN GLIOBLASTOMA

NEURO-ONCOLOGY

IF13.4

2024-11-11

PREAI

Sun, Yusha; Wang, Xin; Zhang, Daniel; Zhang, Zhijian; Bhattarai, Janardhan; Wang, Yingqi; Park, Kristen; Dong, Weifan; Yang, Qian; Zhang, Feng; Rajamani, Keerthi; Mu, Shang; Kennedy, Benjamin; Hong, Yan; Galanaugh, Jamie; Sambangi, Abhijeet; Kim, Sang Hoon; Wheeler, Garrett; Goncalves, Tiago; Wang, Qing; Geschwind, Daniel; Kawaguchi, Riki; Viaene, Angela; Helbig, Ingo; Kessler, Sudha; Hoke, Ahmet; Wang, Huadong; Xu, Fuqiang; Binder, Zev; Chen, Isaac; Pai, Emily Ling-Lin; Stone, Sara; Nasrallah, Maclean; Christian, Kimberly; Fuccillo, Marc; Toni, Nicolas; Wu, Zhuhao; O'Rourke, Donald; Ma, Minghong; Ming, Guo-li; Song, Hongjun

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Altered brain metabolites in male nonhuman primate offspring exposed to maternal immune activation

BRAIN BEHAVIOR AND IMMUNITY

IF7.6

2024-10-01

OAAI

Maddock, Richard J.; Vlasova, Roza M.; Chen, Shuai; Iosif, Ana-Maria; Bennett, Jeffrey; Tanase, Costin; Ryan, Amy M.; Murai, Takeshi; Hogrefe, Casey E.; Schumann, Cynthia D.; Geschwind, Daniel H.; van de Water, Judy; Amaral, David G.; Lesh, Tyler A.; Styner, Martin A.; McAllister, Kimberley; Carter, Cameron S.; Bauman, Melissa D.

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Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids

MOLECULAR PSYCHIATRY

IF10.1

2024-09-30

OAAI

Trudler, Dorit; Ghatak, Swagata; Bula, Michael; Parker, James; Talantova, Maria; Luevanos, Melissa; Labra, Sergio; Grabauskas, Titas; Noveral, Sarah Moore; Teranaka, Mayu; Schahrer, Emily; Dolatabadi, Nima; Bakker, Clare; Lopez, Kevin; Sultan, Abdullah; Patel, Parth; Chan, Agnes; Choi, Yongwook; Kawaguchi, Riki; Stankiewicz, Pawel; Garcia-Bassets, Ivan; Kozbial, Piotr; Rosenfeld, Michael G.; Nakanishi, Nobuki; Geschwind, Daniel H.; Chan, Shing Fai; Lin, Wei; Schork, Nicholas J.; Ambasudhan, Rajesh; Lipton, Stuart A.

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Research Directions