Joseph J. Heijnen - Publications, H-index & Citations

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Joseph J. Heijnen

Delft University of Technology

87H-index

542Paper Count

3.0WCitation Count

Published Papers 157

Publication Date

Comparative performance of different scale-down simulators of substrate gradients in Penicillium chrysogenum cultures: the need of a biological systems response analysis

MICROBIAL BIOTECHNOLOGY

IF5.2

2018-01-15

OAAI

Wang, Guan; Zhao, Junfei; Haringa, Cees; Tang, Wenjun; Xia, Jianye; Chu, Ju; Zhuang, Yingping; Zhang, Siliang; Deshmukh, Amit T.; van Gulik, Walter; Heijnen, Joseph J.; Noorman, Henk J.

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Computational fluid dynamics simulation of an industrial P. chrysogenum fermentation with a coupled 9-pool metabolic model: Towards rational scale-down and design optimization

CHEMICAL ENGINEERING SCIENCE

IF4.3

2018-01-01

OAAI

Haringa, Cees; Tang, Wenjun; Wang, Guan; Deshmukh, Amit T.; van Winden, Wouter A.; Chu, Ju; van Gulik, Walter M.; Heijnen, Joseph J.; Mudde, Robert F.; Noorman, Henk J.

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Power input effects on degeneration in prolonged penicillin chemostat cultures: A systems analysis at flux, residual glucose, metabolite, and transcript levels

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2017-10-06

PREAI

Wang, Guan; Wu, Baofeng; Zhao, Junfei; Haringa, Cees; Xia, Jianye; Chu, Ju; Zhuang, Yingping; Zhang, Siliang; Heijnen, Joseph J.; van Gulik, Walter; Deshmukh, Amit T.; Noorman, Henk J.

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Biochemical engineering's grand adventure

CHEMICAL ENGINEERING SCIENCE

IF4.3

2017-10-01

OAAI

Noorman, Henk J.; Heijnen, Joseph J.

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A 9-pool metabolic structured kinetic model describing days to seconds dynamics of growth and product formation by Penicillium chrysogenum

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2017-05-18

PREAI

Tang, Wenjun; Deshmukh, Amit T.; Haringa, Cees; Wang, Guan; van Gulik, Walter; van Winden, Wouter; Reuss, Matthias; Heijnen, Joseph J.; Xia, Jianye; Chu, Ju; Noorman, Henk J.

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In Vivo Analysis of NH4+ Transport and Central Nitrogen Metabolism in Saccharomyces cerevisiae during Aerobic Nitrogen-Limited Growth

APPLIED AND ENVIRONMENTAL MICROBIOLOGY

IF3.7

2016-12-01

OAAI

Cueto-Rojas, H. F.; Seifar, R. Maleki; ten Pierick, A.; van Helmond, W.; Pieterse, M. M.; Heijnen, J. J.; Wahl, S. A.

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Euler-Lagrange computational fluid dynamics for (bio)reactor scale down: An analysis of organism lifelines

ENGINEERING IN LIFE SCIENCES

IF3

2016-09-14

103

OAAI

Haringa, Cees; Tang, Wenjun; Deshmukh, Amit T.; Xia, Jianye; Reuss, Matthias; Heijnen, Joseph J.; Mudde, Robert F.; Noorman, Henk J.

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Gas bubble induced oil recovery from emulsions stabilised by yeast components

CHEMICAL ENGINEERING SCIENCE

IF4.3

2016-05-01

PREAI

Heeres, Arjan S.; Heijnen, Joseph J.; van der Wielen, Luuk A. M.; Cuellar, Maria C.

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In vivo kinetic analysis of the penicillin biosynthesis pathway using PAA stimulus response experiments

METABOLIC ENGINEERING

IF6.8

2015-11-01

PREAI

Deshmukh, Amit T.; Verheijen, Peter J. T.; Seifar, Reza Maleki; Heijnen, Joseph J.; van Gulik, Walter M.

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Comparative fluxome and metabolome analysis for overproduction of succinate in Escherichia coli

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2015-10-18

PREAI

Taymaz-Nikerel, Hilal; De Mey, Marjan; Baart, Gino J. E.; Maertens, Jo; Foulquie-Moreno, Maria Remedios; Charlier, Daniel; Heijnen, Joseph J.; van Gulik, Walter M.

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Thermodynamics-based design of microbial cell factories for anaerobic product formation

TRENDS IN BIOTECHNOLOGY

IF14.9

2015-09-01

PREAI

Cueto-Rojas, Hugo F.; van Maris, A. J. A.; Wahl, S. Aljoscha; Heijnen, J. J.

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Determination of the Cytosolic NADPH/NADP Ratio in Saccharomyces cerevisiae using Shikimate Dehydrogenase as Sensor Reaction

SCIENTIFIC REPORTS

IF3.9

2015-08-05

OAAI

Zhang, Jinrui; ten Pierick, Angela; van Rossum, Harmen M.; Seifar, Reza Maleki; Ras, Cor; Daran, Jean-Marc; Heijnen, Joseph J.; Wahl, S. Aljoscha

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Fermentation broth components influence droplet coalescence and hinder advanced biofuel recovery during fermentation

BIOTECHNOLOGY JOURNAL

IF3.1

2015-07-16

OAAI

Heeres, Arjan S.; Schroen, Karin; Heijnen, Joseph J.; van der Wielen, Luuk A. M.; Cuellar, Maria C.

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A Fast Sensor For in Vivo Quantification of Cytosolic Phosphate in Saccharomyces Cerevisiae

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2015-01-16

PREAI

Zhang, Jinrui; Sassen, Tom; ten Pierick, Angela; Ras, Cor; Heijnen, Joseph J.; Wahl, Sebastian Aljoscha

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Reconstruction of the oxygen uptake and carbon dioxide evolution rates of microbial cultures at near-neutral pH during highly dynamic conditions

BIOCHEMICAL ENGINEERING JOURNAL

IF3.8

2014-02-01

PREAI

de Jonge, L. P.; Heijnen, J. J.; van Gulik, W. M.

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Flux response of glycolysis and storage metabolism during rapid feast/famine conditions in Penicillium chrysogenum using dynamic 13C labeling

BIOTECHNOLOGY JOURNAL

IF3.1

2013-12-04

PREAI

de Jonge, Lodewijk; Buijs, Nicolaas A. A.; Heijnen, Joseph J.; van Gulik, Walter M.; Abate, Alessandro; Wahl, S. Aljoscha

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Quantitative analysis of intracellular coenzymes in Saccharomyces cerevisiae using ion pair reversed phase ultra high performance liquid chromatography tandem mass spectrometry

JOURNAL OF CHROMATOGRAPHY A

IF4

2013-10-01

PREAI

Seifar, Reza Maleki; Ras, Cor; Deshmukh, Amit T.; Bekers, Katelijne M.; Suarez-Mendez, Camilo A.; da Cruz, Ana L. B.; van Gulik, Walter M.; Heijnen, Joseph J.

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Parameter identification of in vivo kinetic models: Limitations and challenges

BIOTECHNOLOGY JOURNAL

IF3.1

2013-07-01

PREAI

Heijnen, Joseph J.; Verheijen, Peter J. T.

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Large-scale production of diesel-like biofuels - process design as an inherent part of microorganism development

BIOTECHNOLOGY JOURNAL

IF3.1

2013-05-06