Alan P. Fields - Publications, H-index & Citations

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Alan P. Fields

mayo clinic

58H-index

206Paper Count

9.4KCitation Count

Published Papers 71

Publication Date

Molecular basis of allosteric regulation and pharmaceutical targeting of protein kinase Cβ

Nature Communications

IF15.7

2026-05-21

OAAI

Anh T. Q. Cong; Taylor L. Witter; Elizabeth S. Bruinsma; Sayantani Sarkar Bhattacharya; Swaathi Jayaraman; Samuel R. Wyatt; Jasper K. Solverson; Maria B. Dugan; Jasmina Paluncic; Mary J. Kuffel; Julia R. Alvey; Huy V. Huynh; Xinyan Wu; Alan P. Fields; Akhilesh Pandey; John R. Hawse; Matthew P. Goetz; Matthew J. Schellenberg

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Protein kinase Cι dictates tumor trajectory, cell plasticity, and immune surveillance in lung adenocarcinoma

Cell Reports

IF6.9

2025-11-25

OAAI

Duy T. Nguyen; Luis I. Prieto; Cheng Zhang; Hu Li; Andras Khoor; Capella Weems; Lee Jamieson; Karthik B. Jeganathan; Srinidhi R. Babu; Nicole R. Murray; Darren J. Baker; Alan P. Fields

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A lineage-specific role of oncogenic protein kinase C1 in lung adenocarcinoma

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Nguyen, Duy T.; Yin, Ning; Weems, Capella R.; Jamieson, Lee; Meneses, Kayleah; Liu, Yi; Murray, Nicole R.; Fields, Alan P.

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Modeling the 3q26 OncCassette using genetically engineered mice

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Meneses, Kayleah M.; Liu, Yi; Weems, Capella R.; Jamieson, Lee; Nguyen, Duy T.; Justilien, Verline; Murray, Nicole R.; Fields, Alan P.

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A novel combination therapy for lung squamous cell carcinoma

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Alqasrawi, Dania; Argo, Ryan; Rang, Christine Ratliff; Pandya, Prita; Klinge, Skyeler; Lindemann, Jennifer; Searl, Nyla; Fields, Alan; Justilien, Verline

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Endoxifen downregulates AKT phosphorylation through protein kinase C beta 1 inhibition in ERα+ breast cancer

NPJ BREAST CANCER

IF7.6

2023-12-19

OAAI

Jayaraman, Swaathi; Wu, Xinyan; Kalari, Krishna R.; Tang, Xiaojia; Kuffel, Mary J.; Bruinsma, Elizabeth S.; Jalali, Shahrzad; Peterson, Kevin L.; Correia, Cristina; Kudgus, Rachel A.; Kaufmann, Scott H.; Renuse, Santosh; Ingle, James N.; Reid, Joel M.; Ames, Matthew M.; Fields, Alan P.; Schellenberg, Matthew J.; Hawse, John R.; Pandey, Akhilesh; Goetz, Matthew P.

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Characterizing 3q26 copy number gain in lung squamous cell carcinoma through a novel genetically engineered mouse model

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Meneses, Kayleah M.; Weems, Capella; Liu, Yi; Justilien, Verline; Murray, Nicole R.; Fields, Alan P.

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Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth

CANCER RESEARCH

IF16.6

2022-01-04

OAAI

Cook, Danielle R.; Kang, Melissa; Martin, Timothy D.; Galanko, Joseph A.; Loeza, Gabriela H.; Trembath, Dimitri G.; Justilien, Verline; Pickering, Karen A.; Vincent, David F.; Jarosch, Armin; Jurmeister, Philipp; Waters, Andrew M.; Hibshman, Priya S.; Campbell, Andrew D.; Ford, Catriona A.; Keku, Temitope O.; Yeh, Jen Jen; Lee, Michael S.; Cox, Adrienne D.; Fields, Alan P.; Sandler, Robert S.; Sansom, Owen J.; Sers, Christine; Schaefer, Antje; Der, Channing J.

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Protein kinase CI, and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities

CELL REPORTS

IF6.9

2021-11-01

OAAI

Kenchappa, Rajappa S.; Liu, Yi; Argenziano, Michael G.; Banu, Matei A.; Mladek, Ann C.; West, Rita; Luu, Amanda; Quinones-Hinojosa, Alfredo; Hambardzumyan, Dolores; Justilien, Verline; Leitges, Michael; Sarkaria, Jann N.; Sims, Peter A.; Canoll, Peter; Murray, Nicole R.; Fields, Alan P.; Rosenfeld, Steven S.

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FoxM1 insufficiency hyperactivates Ect2-RhoA-mDia1 signaling to drive cancer

NATURE CANCER

IF28.5

2020-10-12

OAAI

Limzerwala, Jazeel F.; Jeganathan, Karthik B.; Kloeber, Jake A.; Davies, Brian A.; Zhang, Cheng; Sturmlechner, Ines; Zhong, Jian; Fierro Velasco, Raul; Fields, Alan P.; Yuan, Yaxia; Baker, Darren J.; Zhou, Daohong; Li, Hu; Katzmann, David J.; van Deursen, Jan M.

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Protein kinase C? promotes UBF1?ECT2 binding on ribosomal DNA to drive rRNA synthesis and transformed growth of non-small-cell lung cancer cells

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-06-01

OAAI

Justilien, Verline; Lewis, Kayla C.; Meneses, Kayleah M.; Jamieson, Lee; Murray, Nicole R.; Fields, Alan P.

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Chromosome 3q26 Gain Is an Early Event Driving Coordinated Overexpression of the PRKCI, SOX2, and ECT2 Oncogenes in Lung Squamous Cell Carcinoma

CELL REPORTS

IF6.9

2020-01-01

OAAI

Liu, Yi; Yin, Ning; Wang, Xue; Khoor, Andras; Sambandam, Vaishnavi; Ghosh, Anwesha B.; Fields, Zoe A.; Murray, Nicole R.; Justilien, Verline; Fields, Alan P.

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Oncogenic PKCι decides tumor-initiating cell fate

CELL CYCLE

IF3.4

2016-07-08

OAAI

Fields, Alan P.; Ali, Syed A.; Murray, Nicole R.

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PKCι regulates nuclear YAP1 localization and ovarian cancer tumorigenesis

ONCOGENE

IF7.3

2016-06-20

OAAI

Wang, Y.; Justilien, V.; Brennan, K. I.; Jamieson, L.; Murray, N. R.; Fields, A. P.

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Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia

NATURE COMMUNICATIONS

IF15.7

2015-02-20

OAAI

Liou, Geou-Yarh; Doeppler, Heike; Braun, Ursula B.; Panayiotou, Richard; Buzhardt, Michele Scotti; Radisky, Derek C.; Crawford, Howard C.; Fields, Alan P.; Murray, Nicole R.; Wang, Q. Jane; Leitges, Michael; Storz, Peter

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Atypical Protein Kinase Cι as a human oncogene and therapeutic target

BIOCHEMICAL PHARMACOLOGY

IF5.6

2014-03-01

OAAI

Parker, Peter J.; Justilien, Verline; Riou, Philippe; Linch, Mark; Fields, Alan P.

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PKCi Maintains a Tumor-initiating Cell Phenotype That Is Required for Ovarian Tumorigenesis

MOLECULAR CANCER RESEARCH

IF4.7

2013-12-17

OAAI

Wang, Yin; Hill, Kristen S.; Fields, Alan P.

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Protein kinase Cα suppresses Kras-mediated lung tumor formation through activation of a p38 MAPK-TGFβ signaling axis

ONCOGENE

IF7.3

2013-04-22

OAAI

Hill, K. S.; Erdogan, E.; Khoor, A.; Walsh, M. P.; Leitges, M.; Murray, N. R.; Fields, A. P.

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Atypical Protein Kinase Cι Is Required for Wnt3a-dependent Neurite Outgrowth and Binds to Phosphorylated Dishevelled 2

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-03-01

OAAI

Greer, Yoshimi Endo; Fields, Alan P.; Brown, Anthony M. C.; Rubin, Jeffrey S.

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Matrix Metalloproteinase Induction of Rac1b, a Key Effector of Lung Cancer Progression

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2012-07-11

OAAI

Stallings-Mann, Melody L.; Waldmann, Jens; Zhang, Ying; Miller, Erin; Gauthier, Mona L.; Visscher, Daniel W.; Downey, Gregory P.; Radisky, Evette S.; Fields, Alan P.; Radisky, Derek C.

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Research Directions