Not logged inTelomere dysfunction alters intestinal stem cell dynamics to promote cancer
Labella, Kyle A.; Hsu, Wen-Hao; Li, Jiexi; Qi, Yutao; Liu, Yonghong; Liu, Jingjing; Wu, Chia -Chin; Liu, Yang; Song, Zingzhi; Lin, Yiyun; Blecher, Jonathan M.; Jiang, Shan; Shang, Xiaoying; Han, Jincheng; Spring, Denise J.; Zhang, Jianhua; Xia, Yan; Depinho, Ronald A. .png)
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SaveShare Save Oncogenic KRAS Drives Lipofibrogenesis to Promote Angiogenesis and Colon Cancer ProgressionHsu, Wen-Hao; LaBella, Kyle A.; Lin, Yiyun; Xu, Ping; Lee, Rumi; Hsieh, Cheng-En; Yang, Lei; Zhou, Ashley; Blecher, Jonathan M.; Wu, Chang-Jiun; Lin, Kangyu; Shang, Xiaoying; Jiang, Shan; Spring, Denise J.; Xia, Yan; Chen, Peiwen; Shen, John Paul; Kopetz, Scott; DePinho, Ronald A. Share Save Histone demethylase KDM5D drives sex-specific differences in colorectal cancerLi, Jiexi; Lan, Zhengdao; Liao, Wenting; Liu, Jielin; Jiang, Shan; Shim, Hong Seok; Slotnik, Max; LaBella, Kyle A.; Hsu, Wen-Hao; Shang, Xiaoying; Spring, Denise; Wang, Y. Alan; DePinho, Ronald A. Share Save Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancerGulhati, Pat; Schalck, Aislyn; Jiang, Shan; Shang, Xiaoying; Wu, Chang-Jiun; Hou, Pingping; Ruiz, Sharia Hernandez; Soto, Luisa Solis; Parra, Edwin; Ying, Haoqiang; Han, Jincheng; Dey, Prasenjit; Li, Jun; Deng, Pingna; Sei, Emi; Maeda, Dean Y.; Zebala, John A.; Spring, Denise J.; Kim, Michael; Wang, Huamin; Maitra, Anirban; Moore, Dirk; Clise-Dwyer, Karen; Wang, Y. Alan; Navin, Nicholas E.; DePinho, Ronald A. Share Save Synthetic Essentiality of Tryptophan 2,3-Dioxygenase 2 in APC-Mutated Colorectal CancerLee, Rumi; Li, Jiexi; Li, Jun; Wu, Chang-Jiun; Jiang, Shan; Hsu, Wen-Hao; Chakravarti, Deepavali; Chen, Peiwen; LaBella, Kyle A.; Li, Jing; Spring, Denise J.; Zhao, Di; Wang, Y. Alan; DePinho, Ronald A. Share Save AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylaseYoshihama, Yohei; LaBella, Kyle A.; Kim, Eiru; Bertolet, Lori; Colic, Medina; Li, Jiexi; Shang, Xiaoying; Wu, Chang-Jiun; Spring, Denise J.; Wang, Y. Alan; Hart, Traver; DePinho, Ronald A. Share Save Telomere dysfunction instigates inflammation in inflammatory bowel diseaseChakravarti, Deepavali; Lee, Rumi; Multani, Asha S.; Santoni, Andrea; Keith, Zachery; Hsu, Wen-Hao; Chang, Kyle; Reyes, Laura; Rashid, Asif; Wu, Chang-Jiun; Li, Jun; Zhang, Jiexin; Shim, Hong Seok; Chandra, Krishna; Deng, Pingna; Spring, Denise J.; Nielsen, Ole Haagen; Riis, Lene Buhl; Mayigegowda, Kavya Kelagere; Blutt, Sarah E.; Zhang, Jianhua; Younes, Mamoun; DuPont, Andrew; Thirumurthi, Selvi; Vilar, Eduardo; Estes, Mary K.; Colla, Simona; Shroyer, Noah F.; DePinho, Ronald A. Share Save Telomere dysfunction activates YAP1 to drive tissue inflammationChakravarti, Deepavali; Hu, Baoli; Mao, Xizeng; Rashid, Asif; Li, Jiexi; Li, Jun; Liao, Wen-ting; Whitley, Elizabeth M.; Dey, Prasenjit; Hou, Pingping; LaBella, Kyle A.; Chang, Andrew; Wang, Guocan; Spring, Denise J.; Deng, Pingna; Zhao, Di; Liang, Xin; Lan, Zhengdao; Lin, Yiyun; Sarkar, Sharmistha; Terranova, Christopher; Deribe, Yonathan Lissanu; Blutt, Sarah E.; Okhuysen, Pablo; Zhang, Jianhua; Vilar, Eduardo; Nielsen, Ole Haagen; Dupont, Andrew; Younes, Mamoun; Patel, Kalyani R.; Shroyer, Noah F.; Rai, Kunal; Estes, Mary K.; Wang, Y. Alan; Bertuch, Alison A.; DePinho, Ronald A. Share Save Chromatin Regulator CHD1 Remodels the Immunosuppressive Tumor Microenvironment, in PTEN-Deficient Prostate CancerZhao, Di; Cai, Li; Lu, Xin; Liang, Xin; Li, Jiexi; Chen, Peiwen; Ittmann, Michael; Shang, Xiaoying; Jiang, Shan; Li, Haoyan; Meng, Chenling; Flores, Ivonne; Song, Jian H.; Horner, James W.; Lan, Zhengdao; Wu, Chang-Jiun; Li, Jun; Chang, Qing; Chen, Ko-Chien; Wang, Guocan; Deng, Pingna; Spring, Denise J.; Wang, Y. Alan; DePinho, Ronald A. Share Save YAP in cancer and inflammationWang, Guocan; Lu, Xin; Chakravarti, Deepavali; Kapoor, Avnish; Yao, Wantong; Ying, Haoqiang; Dey, Prasenjit; Wu, Chiachin; Spring, Denise; Hou, Pingping; Deng, Pingna; Zhao, Di; Hu, Baoli; Xizeng, Mao; Logothesis, Christopher; McArthur, Michael; Chin, Lynda; Wang, Alan; Hua, Sujun; Xia, Hongai; Chu, Gerald C.; Lim, Carol; Vilar, Eduardo; Blutt, Sarah; DePinho, Ronald A. Share Save Tumor Microenvironment Remodeling Enables Bypass of Oncogenic KRAS Dependency in Pancreatic CancerHou, Pingping; Kapoor, Avnish; Zhang, Qiang; Li, Jiexi; Wu, Chang-Jiun; Li, Jun; Lan, Zhengdao; Tang, Ming; Ma, Xingdi; Ackroyd, Jeffrey J.; Kalluri, Raghu; Zhang, Jianhua; Jiang, Shan; Spring, Denise J.; Wang, Y. Alan; DePinho, Ronald A. Share Save Oncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor MicroenvironmentDey, Prasenjit; Li, Jun; Zhang, Jianhua; Chaurasiya, Surendra; Strom, Anders; Wang, Huamin; Liao, Wen-Ting; Cavallaro, Frederick; Denz, Parker; Bernard, Vincent; Yen, Er-Yen; Genovese, Giannicola; Gulhati, Pat; Liu, Jielin; Chakravarti, Deepavali; Deng, Pingna; Zhang, Tingxin; Carbone, Federica; Chang, Qing; Ying, Haoqiang; Shang, Xiaoying; Spring, Denise J.; Ghosh, Bidyut; Putluri, Nagireddy; Maitra, Anirban; Wang, Y. Alan; DePinho, Ronald A. Share Save Circadian Regulator CLOCK Recruits Immune-Suppressive Microglia into the GBM Tumor MicroenvironmentChen, Peiwen; Hsu, Wen-Hao; Chang, Andrew; Tan, Zhi; Lan, Zhengdao; Zhou, Ashley; Spring, Denise J.; Lang, Frederick F.; Wang, Y. Alan; DePinho, Ronald A. Share Save Telomere dysfunction is a driver of inflammatory bowel diseaseChakravarti, Deepavali; Multani, Asha; Dey, Prasenjit; Hu, Baoli; Zhao, Di; Chang, Kyle; Xizeng, Mao; Wang, Guocan; Terranova, Christoper; Liao, Wen-Ting; Spring, Denise; Hou, Pingping; Zhang, Jianhua; Okhuysen, Pablo; Vilar, Eduardo; Estes, Mary K.; Blutt, Sarah; Wang, Alan; DePinho, Ronald Share Save PAF promotes stemness and radioresistance of glioma stem cellsOng, Derrick Sek Tong; Hu, Baoli; Ho, Yan Wing; Sauve, Charles-Etienne Gabriel; Bristow, Christopher A.; Wang, Qianghu; Multani, Asha S.; Chen, Peiwen; Nezi, Luigi; Jiang, Shan; Gorman, Claire Elizabeth; Monasterio, Marta Moreno; Koul, Dimpy; Marchesini, Matteo; Colla, Simona; Jin, Eun-Jung; Sulman, Erik P.; Spring, Denise J.; Yung, Wai-Kwan Alfred; Verhaak, Roel G. W.; Chin, Lynda; Wang, Y. Alan; DePinho, Ronald A. Share Save Share Save Share Save Share Save Response to letter regarding article, Protease-Activated Receptor-1 Contributes to Cardiac Remodeling and HypertrophyPawlinski, Rafal; Tencati, Michael; Hampton, Craig R.; Spring, Denise; Pohlman, Timothy H.; Verrier, Edward D.; Shishido, Tetsuro; Bullard, Tara A.; Casey, Liam M.; Abe, Jun-ichi; Blaxall, Burns C.; Andrade-Gordon, Patricia; Kotzsch, Matthias; Luther, Thomas; Mackman, Nigel Share Save 
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