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Spatial analysis reveals targetable macrophage-mediated mechanisms of immune evasion in hepatocellular carcinoma minimal residual disease Lemaitre, Lea; Adeniji, Nia; Suresh, Akanksha; Reguram, Reshma; Zhang, Josephine; Park, Jangho; Reddy, Amit; Trevino, Alexandro E.; Mayer, Aaron T.; Deutzmann, Anja; Hansen, Aida S.; Tong, Ling; Arjunan, Vinodhini; Kambham, Neeraja; Visser, Brendan C.; Dua, Monica M.; Bonham, C. Andrew; Kothary, Nishita; D'Angio, H. Blaize; Preska, Ryan; Rosen, Yanay; Zou, James; Charu, Vivek; Felsher, Dean W.; Dhanasekaran, Renumathy Share Save
A novel SDC1-targeted therapeutic antibody inhibits macropinocytosis and induces anti-tumor immunity in pancreatic cancer Yang, Zecheng; Theardy, Madelaine S.; Chen, Shuaitong; Wei, Yongkun; Takeda, Mitsunobu; Wang, Xiaofei; Yao, Jun; Li, Jennifer; Park, Jangho; Zheng, Yangxi; Vien, Long T.; Bover, Laura; Ying, Haoqiang; Yao, Wantong Share Save
Blockade of CD24 sensitizes pancreatic cancer to Kras inhibitors Wei, Yongkun; Liu, Minghui; Yen, Er-Yen; Yao, Jun; Nguyen, Phuoc T.; Wang, Xiaofei; Yang, Zecheng; Yousef, Abdelrahman; Pan, Dean; Jin, Yanqing; Theady, Madelaine S.; Park, Jangho; Cai, Yiming; Takeda, Mitsunobu; Vasquez, Matthew; Zhou, Yong; Zhao, Hong; Viale, Andrea; Wang, Huamin; Zhao, Dan; DePinho, Ronald A.; Yao, Wantong; Ying, Haoqiang Share Save
Bi-steric mTORC1-selective inhibitors activate 4EBP1, suppress MYC, restore anti-tumor immunity, and cooperate with immune checkpoint inhibition to elicit tumor regression Mahauad-Fernandez, Wadie D.; Yang, Yu Chi; Lai, Ian; Park, Jangho; Yao, Lilian; Evans, James W.; Atibalentja, Danielle F.; Chen, Xinyu; Zhao, Zihui; Burnett, G. Leslie; Lee, Bianca J.; Dinglasan, Nuntana; Shifrin, Nataliya; Ahler, Ethan; Quintana, Elsa; Gill, Adrian; Smith, Jacqueline A.; Singh, Mallika; Felsher, Dean W. Share Save
MYC Overexpression Drives Immune Evasion in Hepatocellular Carcinoma That Is Reversible through Restoration of Proinflammatory Macrophages Dhanasekaran, Renumathy; Hansen, Aida S.; Park, Jangho; Lemaitre, Lea; Lai, Ian; Adeniji, Nia; Kuruvilla, Sibu; Suresh, Akanksha; Zhang, Josephine; Swamy, Varsha; Felsher, Dean W. Share Save
Genomic Analysis of Vascular Invasion in HCC Reveals Molecular Drivers and Predictive Biomarkers Krishnan, Maya S.; Rajan, Anand K. D.; Park, Jangho; Arjunan, Vinodhini; Marques, Fernando Jose Garcia; Bermudez, Abel; Girvan, Olivia A.; Hoang, Nam S.; Yin, Jun; Nguyen, Mindie H.; Kothary, Nishita; Pitteri, Sharon; Felsher, Dean W.; Dhanasekaran, Renumathy Share Save
MYC ASO Impedes Tumorigenesis and Elicits Oncogene Addiction in Autochthonous Transgenic Mouse Models of HCC and RCC Dhanasekaran, Renumathy; Park, Jangho; Yevtodiyenko, Alekesey; Bellovin, David I.; Adam, Stacey J.; Rajan, Anand; Gabay, Meital; Fernando, Hanan; Arzeno, Julia; Arjunan, Vinodhini; Gryanzov, Sergei; Felsher, Dean W. Share Save
MYC and Twist1 cooperate to drive metastasis by eliciting crosstalk between cancer and innate immunity Dhanasekaran, Renumathy; Baylot, Virginie; Kim, Minsoon; Kuruvilla, Sibu; Bellovin, David, I; Adeniji, Nia; Rajan, Anand; Lai, Ian; Gabay, Meital; Tong, Ling; Krishnan, Maya; Park, Jangho; Hu, Theodore; Barbhuiya, Mustafa A.; Gentles, Andrew J.; Kannan, Kasthuri; Tran, Phuoc T.; Felsher, Dean W. Share Save
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