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M

Malvina Papanastasiou

MIT and Harvard

24H-index
96Paper Count
2.4KCitation Count
Published Papers 32
Publication Date
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Nano-scaled, fully automated hydrogen/deuterium exchange for analysis of macromolecular assemblies reaching the MDa scale
errMolecular & Cellular Proteomics
IF5.5
err2026-01-29
err0
errOAAI
errShaunak Raval; Yuqi Shi; Julia W. Morriss; Alexander R. Ivanov; Stephen Coales; Inna Aphasizheva; Ruslan Aphasizhev; Brian B. Liau; Steven A. Carr; Malvina Papanastasiou
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A SWI/SNF-specific Ig-like domain; SWIFT; is a transcription factor binding platform
errScience
IF45.8
err2026-01-01
err0
PREAI
errSiddhant U. Jain; Kaylyn E. Williamson; Alexander W. Ying; Aasha M. Turner; Ruidong Jerry Jiang; Shaunak Raval; Kevin So; Maxwell J. Allison; Akshay Sankar; Daniel D. Sáme Guerra; Yutong Lin; Zhe Jiang; Nazar Mashtalir; Henry W. Rohrs; Cheryl F. Lichti; Tom W. Muir; Malvina Papanastasiou; Joao A. Paulo; Steven P. Gygi; Michael L. Gross; Cigall Kadoch
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errSave
Mass spectrometry-based profiling of single-cell histone post-translational modifications to dissect chromatin heterogeneity
errNature Communications
IF15.7
err2025-12-12
err0
errOAAI
errRonald Cutler; Laura Corveleyn; Claudia Ctortecka; Francesca LiCausi; Joshua Cantlon; Alvaro Sebastian Vaca Jacome; Dieter Deforce; Jan Vijg; Maarten Dhaenens; Malvina Papanastasiou; Steven A. Carr; Simone Sidoli
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errSave
Corrigendum to “Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data”
errMolecular & Cellular Proteomics
IF5.5
err2025-08-07
err0
PREAI
errDušica Vidović; Behrouz Shamsaei; Stephan C. Schürer; Phillip Kogan; Szymon Chojnacki; Michal Kouril; Mario Medvedovic; Wen Niu; Evren U. Azeloglu; Marc R. Birtwistle; Yibang Chen; Tong Chen; Jens Hansen; Bin Hu; Ravi Iyengar; Gomathi Jayaraman; Hong Li; Tong Liu; Eric A. Sobie; Yuguang Xiong; Matthew J. Berberich; Gary Bradshaw; Mirra Chung; Robert A. Everley; Ben Gaudio; Marc Hafner; Marian Kalocsay; Caitlin E. Mills; Maulik K. Nariya; Peter K. Sorger; Kartik Subramanian; Chiara Victor; Maria Banuelos; Victoria Dardov; Ronald Holewinski; Danica-Mae Manalo; Berhan Mandefro; Andrea D. Matlock; Loren Ornelas; Dhruv Sareen; Clive N. Svendsen; Vineet Vaibhav; Jennifer E. Van Eyk; Vidya Venkatraman; Steve Finkbiener; Ernest Fraenkel; Jeffrey Rothstein; Leslie Thompson; Jacob Asiedu; Steven A. Carr; Karen E. Christianson; Desiree Davison; Deborah O. Dele-Oni; Katherine C. DeRuff; Shawn B. Egri; Alvaro Sebastian Vaca Jacome; Jacob D. Jaffe; Daniel Lam; Lev Litichevskiy; Xiaodong Lu; James Mullahoo; Adam Officer; Malvina Papanastasiou; Ryan Peckner; Caidin Toder; Joel Blanchard; Michael Bula; Tak Ko; Li-Huei Tsai; Jennie Z. Young; Vagisha Sharma; Jarek Meller; Michael J. MacCoss
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errSave
Chemical perturbations impacting histone acetylation govern colorectal cancer differentiation
errGastroenterology
IF25.1
err2025-07-07
err0
errOAAI
errPornlada Likasitwatanakul; Zhixin Li; Paul Doan; Sandor Spisak; Akhouri Kishore Raghawan; Qi Liu; Priscilla Liow; Sunwoo Lee; David Chen; Pratyusha Bala; Pranshu Sahgal; Daulet Aitymbayev; Jennifer S. Thalappillil; Malvina Papanastasiou; William Hawkins; Steven A. Carr; Haeseong Park; James M. Cleary; Jun Qi; Nilay S. Sethi
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errSave
High-Throughput Determination of Exchange Rates of Unmodified and PTM-Containing Peptides Using HX-MS
errMOLECULAR & CELLULAR PROTEOMICS
IF5.5
err2025-02-01
err0
errOAAI
errMoroco, Jamie A.; Jacome, Alvaro Sebastian Vaca; Beltran, Pierre Michel Jean; Reiter, Andrew; Mundorff, Charlie; Guttman, Miklos; Morrow, Jeff; Coales, Stephen; Mayne, Leland; Hamuro, Yoshitomo; Carr, Steven A.; Papanastasiou, Malvina
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ZBTB7A is a modulator of KDM5-driven transcriptional networks in basal breast cancer
errCELL REPORTS
IF6.9
err2024-12-01
err0
PREAI
errDiciaccio, Benedetto; Seehawer, Marco; Li, Zheqi; Patmanidis, Andriana; Bui, Triet; Foidart, Pierre; Nishida, Jun; D'Santos, Clive S.; Papachristou, Evangelia K.; Papanastasiou, Malvina; Reiter, Andrew H.; Qiu, Xintao; Li, Rong; Jiang, Yijia; Huang, Xiao-Yun; Simeonov, Anton; Kales, Stephen C.; Rai, Ganesha; Lal-Nag, Madhu; Jadhav, Ajit; Brown, Myles; Carroll, Jason S.; Long, Henry W.; Polyak, Kornelia
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Identifying mitigating strategies for endothelial cell dysfunction and hypertension in response to VEGF receptor inhibitors
errCLINICAL SCIENCE
IF7.7
err2024-09-16
err2
PREAI
errCamarda, Nicholas D.; Lu, Qing; Meola, Dawn M.; Man, Joshua J.; Song, Zeyuan; Travers, Richard J.; Lopez, Katherine E.; Powers, Sarah N.; Papanastasiou, Malvina; Deruff, Katherine C.; Mullahoo, James; Egri, Shawn B.; Davison, Desiree; Sebastiani, Paola; Eblen, Scott T.; Buchsbaum, Rachel; Huggins, Gordon S.; London, Cheryl A.; Jaffe, Jacob D.; Upshaw, Jenica N.; Yang, Vicky K.; Jaffe, Iris Z.
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Loss of Kmt2c or Kmt2d drives brain metastasis via KDM6A-dependent upregulation of MMP3
errNATURE CELL BIOLOGY
IF19.1
err2024-06-26
err4
errOAAI
errSeehawer, Marco; Li, Zheqi; Nishida, Jun; Foidart, Pierre; Reiter, Andrew H.; Rojas-Jimenez, Ernesto; Goyette, Marie-Anne; Yan, Pengze; Raval, Shaunak; Munoz Gomez, Miguel; Cejas, Paloma; Long, Henry W.; Papanastasiou, Malvina; Polyak, Kornelia
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An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing
errMOLECULAR CELL
IF16.6
err2024-06-01
err2
PREAI
errWaterbury, Amanda L.; Kwok, Hui Si; Lee, Ceejay; Narducci, Domenic N.; Freedy, Allyson M.; Su, Cindy; Raval, Shaunak; Reiter, Andrew H.; Hawkins, William; Lee, Kwangwoon; Li, Jiaming; Hoenig, Samuel M.; Vinyard, Michael E.; Cole, Philip A.; Hansen, Anders S.; Carr, Steven A.; Papanastasiou, Malvina; Liau, Brian B.
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KDM4C histone demethylase connects redox balance to chromatin remodeling via histone H3 tail clipping
errCANCER RESEARCH
IF16.6
err2024-02-01
err0
PREAI
errLi, Zheqi; Peluffo, Guillermo; Stevens, Laura; Qiu, Xintao; Seehawer, Marco; Huang, Xiao-Yun; Egri, Shawn; Papanastasiou, Malvina; Kingston, Natalie; D'Santos, Clive; Papachristou, Eva; Nishida, Jun; Evans, Kyle; Seo, Ji-Heui; Clement, Kendell; Temko, Daniel; Ekram, Muhammad; Rees, Matthew; Ronan, Melissa; Roth, Jennifer; Simeonov, Anton; Kales, Stephen; Rai, Ganesha; Lal-Nag, Madhu; Maloney, David; Jadhav, Ajit; Michor, Franziska; Meissner, Alex; Balko, Justin; Carroll, Jason; Freedman, Matthew; Long, Henry; Jaffe, Jacob; Polyak, Kornelia
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Heterogeneity and transcriptional drivers of triple-negative breast cancer
errCELL REPORTS
IF6.9
err2023-12-01
err5
errOAAI
errJovanovic, Bojana; Temko, Daniel; Stevens, Laura E.; Seehawer, Marco; Fassl, Anne; Murphy, Katherine; Anand, Jayati; Garza, Kodie; Gulvady, Anushree; Qiu, Xintao; Harper, Nicholas W.; Daniels, Veerle W.; Huang, Xiao-Yun; Ge, Jennifer Y.; Aleckovic, Masa; Pyrdol, Jason; Hinohara, Kunihiko; Egri, Shawn B.; Papanastasiou, Malvina; Vadhi, Raga; Font-Tello, Alba; Witwicki, Robert; Peluffo, Guillermo; Trinh, Anne; Shu, Shaokun; Diciaccio, Benedetto; Ekram, Muhammad B.; Subedee, Ashim; Herbert, Zachary T.; Wucherpfennig, Kai W.; Letai, Anthony G.; Jaffe, Jacob D.; Sicinski, Piotr; Brown, Myles; Dillon, Deborah; Long, Henry W.; Michor, Franziska; Polyak, Kornelia
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ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling
errNATURE COMMUNICATIONS
IF15.7
err2023-02-04
err42
errOAAI
errGentili, Matteo; Liu, Bingxu; Papanastasiou, Malvina; Dele-Oni, Deborah; Schwartz, Marc A.; Carlson, Rebecca J.; Al'Khafaji, Aziz M.; Krug, Karsten; Brown, Adam; Doench, John G.; Carr, Steven A.; Hacohen, Nir
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JAK-STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States
errCANCER RESEARCH
IF16.6
err2022-11-21
err42
errOAAI
errStevens, Laura E.; Peluffo, Guillermo; Qiu, Xintao; Temko, Daniel; Fassl, Anne; Li, Zheqi; Trinh, Anne; Seehawer, Marco; Jovanovic, Bojana; Aleckovic, Masa; Wilde, Callahan M.; Geck, Renee C.; Shu, Shaokun; Kingston, Natalie L.; Harper, Nicholas W.; Almendro, Vanessa; Pyke, Alanna L.; Egri, Shawn B.; Papanastasiou, Malvina; Clement, Kendell; Zhou, Ningxuan; Walker, Sarah; Salas, Jacqueline; Park, So Yeon; Frank, David A.; Meissner, Alexander; Jaffe, Jacob D.; Sicinski, Piotr; Toker, Alex; Michor, Franziska; Long, Henry W.; Overmoyer, Beth A.; Polyak, Kornelia
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errSave
A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses
errCOMMUNICATIONS BIOLOGY
IF5.1
err2022-10-07
err14
errOAAI
errGross, Sean M.; Dane, Mark A.; Smith, Rebecca L.; Devlin, Kaylyn L.; McLean, Ian C.; Derrick, Daniel S.; Mills, Caitlin E.; Subramanian, Kartik; London, Alexandra B.; Torre, Denis; Evangelista, John Erol; Clarke, Daniel J. B.; Xie, Zhuorui; Erdem, Cemal; Lyons, Nicholas; Natoli, Ted; Pessa, Sarah; Lu, Xiaodong; Mullahoo, James; Li, Jonathan; Adam, Miriam; Wassie, Brook; Liu, Moqing; Kilburn, David F.; Liby, Tiera A.; Bucher, Elmar; Sanchez-Aguila, Crystal; Daily, Kenneth; Omberg, Larsson; Wang, Yunguan; Jacobson, Connor; Yapp, Clarence; Chung, Mirra; Vidovic, Dusica; Lu, Yiling; Schurer, Stephan; Lee, Albert; Pillai, Ajay; Subramanian, Aravind; Papanastasiou, Malvina; Fraenkel, Ernest; Feiler, Heidi S.; Mills, Gordon B.; Jaffe, Jake D.; Ma'ayan, Avi; Birtwistle, Marc R.; Sorger, Peter K.; Korkola, James E.; Gray, Joe W.; Heiser, Laura M.
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Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors
errCELL STEM CELL
IF20.4
err2022-01-01
err49
errOAAI
errMeharena, Hiruy S.; Marco, Asaf; Dileep, Vishnu; Lockshin, Elana R.; Akatsu, Grace Y.; Mullahoo, James; Watson, L. Ashley; Ko, Tak; Guerin, Lindsey N.; Abdurrob, Fatema; Rengarajan, Shruthi; Papanastasiou, Malvina; Jaffe, Jacob D.; Tsai, Li-Huei
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errSave
Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase
errNATURE COMMUNICATIONS
IF15.7
err2021-07-16
err50
errOAAI
errGarvie, Colin W.; Wu, Xiaoyun; Papanastasiou, Malvina; Lee, Sooncheol; Fuller, James; Schnitzler, Gavin R.; Horner, Steven W.; Baker, Andrew; Zhang, Terry; Mullahoo, James P.; Westlake, Lindsay; Hoyt, Stephanie H.; Toetzl, Marcus; Ranaghan, Matthew J.; de Waal, Luc; McGaunn, Joseph; Kaplan, Bethany; Piccioni, Federica; Yang, Xiaoping; Lange, Martin; Tersteegen, Adrian; Raymond, Donald; Lewis, Timothy A.; Carr, Steven A.; Cherniack, Andrew D.; Lemke, Christopher T.; Meyerson, Matthew; Greulich, Heidi
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Dual protease type XIII/pepsin digestion offers superior resolution and overlap for the analysis of histone tails by HX-MS
errMETHODS
IF4.3
err2020-12-01
err15
errOAAI
errMullahoo, James; Zhang, Terry; Clauser, Karl; Carr, Steven A.; Jaffe, Jacob D.; Papanastasiou, Malvina
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Chasing Tails: Cathepsin-L Improves Structural Analysis of Histones by HX-MS
errMOLECULAR & CELLULAR PROTEOMICS
IF5.5
err2019-10-01
err6
errOAAI
errPapanastasiou, Malvina; Mullahoo, James; DeRuff, Katherine C.; Bajrami, Besnik; Karageorgos, Ioannis; Johnston, Stephen E.; Peckner, Ryan; Myers, Samuel A.; Carr, Steven A.; Jaffe, Jacob D.
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errSave
Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb
errANALYTICAL CHEMISTRY
IF6.7
err2019-05-02
err45
errOAAI
errHudgens, Jeffrey W.; Gallagher, Elyssia S.; Karageorgos, Ioannis; Anderson, Kyle W.; Filliben, James J.; Huang, Richard Y. -C.; Chen, Guodong; Bou-Assaf, George M.; Espada, Alfonso; Chalmers, Michael J.; Harguindey, Eduardo; Zhang, Hui-Min; Walters, Benjamin T.; Zhang, Jennifer; Venable, John; Steckler, Caitlin; Park, Inhee; Brock, Ansgar; Lu, Xiaojun; Pandey, Ratnesh; Chandramohan, Arun; Anand, Ganesh Srinivasan; Nirudodhi, Sasidhar N.; Sperry, Justin B.; Rouse, Jason C.; Carroll, James A.; Rand, Kasper D.; Leurs, Ulrike; Weis, David D.; Al-Naqshabandi, Mohammed A.; Hageman, Tyler S.; Deredge, Daniel; Wintrode, Patrick L.; Papanastasiou, Malvina; Lambris, John D.; Li, Sheng; Urata, Sarah
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Research Directions

No research directions
Co-authors
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