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Aβ plaques induce local pre-synaptic toxicity in human iPSC-derived neuron xenografts Van Vierbergen, Jacqueline Frederique Maria; Calatayud, Carles; Balusu, Sriram; Carfano, Nicolo; Peredo, Nicolas; Vints, Katlijn; Gallego, Sandra Fernandez; Horre, Katrien; De Strooper, Bart; Verstreken, Patrik Share Save
Functional characterization of a human epilepsy-associated gene network reveals metabolic regulation as a critical factor underlying seizure susceptibilities Long, Jingyi; Jones, Spencer G.; Serna, Ana; van Reijmersdal, Boyd; Kampshoff, Franziska; Aibar, Sara; Verstreken, Patrik; Huynen, Martijn A.; Coll-Tane, Mireia; Schenck, Annette Share Save
Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity Martin, E; Giakoumakis, D; Paesmans, J; Bisi, N; Drozdzecki, A; Audenaert, D; Haustraete, J; Verstreken, P; Galicia, C; Ballet, S; Versées, W Share Save
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A candidate loss-of-function variant in SGIP1 causes synaptic dysfunction and recessive parkinsonism Decet, Marianna; Scott, Patrick; Kuenen, Sabine; Meftah, Douja; Swerts, Jef; Calatayud, Carles; Gallego, Sandra F.; Kaempf, Natalie; Nachman, Eliana; Praschberger, Roman; Schoovaerts, Nils; Tang, Chris C.; Eidelberg, David; Al Adawi, Samir; Al Asmi, Abdullah; Nandhagopal, Ramachandiran; Verstreken, Patrik Share Save
Drosophila appear resistant to trans-synaptic tau propagation Catterson, James H.; Mouofo, Edmond N.; Soler, Ines Lopez De Toledo; Lean, Gillian; Dlamini, Stella; Liddell, Phoebe; Voong, Graham; Katsinelos, Taxiarchis; Wang, Yu-Chun; Schoovaerts, Nils; Verstreken, Patrik; Spires-Jones, Tara L.; Durrant, Claire S. Share Save
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EndophilinA-dependent coupling between activity-induced calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation Bademosi, Adekunle T.; Decet, Marianna; Kuenen, Sabine; Calatayud, Carles; Swerts, Jef; Gallego, Sandra F.; Schoovaerts, Nils; Karamanou, Spyridoula; Louros, Nikolaos; Martin, Ella; Sibarita, Jean-Baptiste; Vints, Katlijn; Gounko, Natalia V.; Meunier, Frederic A.; Economou, Anastassios; Versees, Wim; Rousseau, Frederic; Schymkowitz, Joost; Soukup, Sandra-F.; Verstreken, Patrik Share Save
Neuronal identity defines a-synuclein and tau toxicity Praschberger, Roman; Kuenen, Sabine; Schoovaerts, Nils; Kaempf, Natalie; Singh, Jeevanjot; Janssens, Jasper; Swerts, Jef; Nachman, Eliana; Calatayud, Carles; Aerts, Stein; Poovathingal, Suresh; Verstreken, Patrik Share Save
Tyrosyl-tRNA synthetase has a noncanonical function in actin bundling Ermanoska, Biljana; Asselbergh, Bob; Morant, Laura; Petrovic-Erfurth, Maria-Luise; Hosseinibarkooie, Seyyedmohsen; Leitao-Goncalves, Ricardo; Almeida-Souza, Leonardo; Bervoets, Sven; Sun, Litao; Lee, LaTasha; Atkinson, Derek; Khanghahi, Akram; Tournev, Ivaylo; Callaerts, Patrick; Verstreken, Patrik; Yang, Xiang-Lei; Wirth, Brunhilde; Rodal, Avital A.; Timmerman, Vincent; Goode, Bruce L.; Godenschwege, Tanja A.; Jordanova, Albena Share Save
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Parkinsonism mutations in DNAJC6 cause lipid defects and neurodegeneration that are rescued by Synj1 Jacquemyn, Julie; Kuenen, Sabine; Swerts, Jef; Pavie, Benjamin; Vijayan, Vinoy; Kilic, Ayse; Chabot, Dries; Wang, Yu-Chun; Schoovaerts, Nils; Corthout, Nikky; Verstreken, Patrik Share Save
A reference human induced pluripotent stem cell line for collaborative studies Pantazis, Caroline B.; Yang, Andrian; Lara, Erika; McDonough, Justin A.; Blauwendraat, Cornelis; Peng, Lirong; Oguro, Hideyuki; Kanaujiya, Jitendra; Zou, Jizhong; Sebesta, David; Pratt, Gretchen; Cross, Erin; Blockwick, Jeffrey; Buxton, Philip; Kinner-Bibeau, Lauren; Medura, Constance; Tompkins, Christopher; Hughes, Stephen; Santiana, Marianita; Faghri, Faraz; Nalls, Mike A.; Vitale, Daniel; Ballard, Shannon; Qi, Yue A.; Ramos, Daniel M.; Anderson, Kailyn M.; Stadler, Julia; Narayan, Priyanka; Papademetriou, Jason; Reilly, Luke; Nelson, Matthew P.; Aggarwal, Sanya; Rosen, Leah U.; Kirwan, Peter; Pisupati, Venkat; Coon, Steven L.; Scholz, Sonja W.; Priebe, Theresa; Ottl, Miriam; Dong, Jian; Meijer, Marieke; Janssen, Lara J. M.; Lourenco, Vanessa S.; van der Kant, Rik; Crusius, Dennis; Paquet, Dominik; Raulin, Ana-Caroline; Bu, Guojun; Held, Aaron; Wainger, Brian J.; Gabriele, Rebecca M. C.; Casey, Jackie M.; Wray, Selina; Abu-Bonsrah, Dad; Parish, Clare L.; Beccari, Melinda S.; Cleveland, Don W.; Li, Emmy; Rose, Indigo V. L.; Kampmann, Martin; Aristoy, Carles Calatayud; Verstreken, Patrik; Heinrich, Laurin; Chen, Max Y.; Schule, Birgitt; Dou, Dan; Holzbaur, Erika L. F.; Zanellati, Maria Clara; Basundra, Richa; Deshmukh, Mohanish; Cohen, Sarah; Khanna, Richa; Raman, Malavika; Nevin, Zachary S.; Matia, Madeline; Van Lent, Jonas; Timmerman, Vincent; Conklin, Bruce R.; Chase, Katherine Johnson; Zhang, Ke; Funes, Salome; Bosco, Daryl A.; Erlebach, Lena; Welzer, Marc; Kronenberg-Versteeg, Deborah; Lyu, Guochang; Arenas, Ernest; Coccia, Elena; Sarrafha, Lily; Ahfeldt, Tim; Marioni, John C.; Skarnes, William C.; Cookson, Mark R.; Ward, Michael E.; Merkle, Florian T. Share Save
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