Not logged in CircHTT(2,3,4,5,6) - co-evolving with the HTT CAG-repeat tract - modulates Huntington's disease phenotypes Morandell, Jasmin; Monziani, Alan; Lazioli, Martina; Donzel, Deborah; Doring, Jessica; Pegorar, Claudio Oss; D'Anzi, Angela; Pellegrini, Miguel; Mattiello, Andrea; Bortolotti, Dalia; Bergonzoni, Guendalina; Tripathi, Takshashila; Mattis, Virginia B.; Kovalenko, Marina; Rosati, Jessica; Dieterich, Christoph; Dassi, Erik; Wheeler, Vanessa C.; Ellederova, Zdenka; Wilusz, Jeremy E.; Viero, Gabriella; Biagioli, Marta Share Save
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CIRCHTT, A CIRCULAR RNA FROM THE HUNTINGTON'S DISEASE GENE LOCUS: FUNCTIONAL CHARACTERIZATION AND POSSIBLE IMPLICATIONS FOR DISEASE MODULATION Doring, Jessica; Ferrari, Simone; Monziani, Alan; Pegorar, Claudio Oss; Tripathi, Takshashila; Di Leva, Francesca; Kerschbamer, Emanuela; Mattis, Virginia B.; Dieterich, Christoph; Dassi, Erik; Wheeler, Vanessa C.; Hansikova, Hana; Ellederova, Zdenka; Wilusz, Jeremy E.; Biagioli, Marta Share Save
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The difficulty to model Huntington's disease in vitro using striatal medium spiny neurons differentiated from human induced pluripotent stem cells Le Cann, Kim; Foerster, Alec; Roesseler, Corinna; Erickson, Andelain; Hautvast, Petra; Giesselmann, Sebastian; Pensold, Daniel; Kurth, Ingo; Rothermel, Markus; Mattis, Virginia B.; Zimmer-Bensch, Geraldine; von Hoersten, Stephan; Denecke, Bernd; Clarner, Tim; Meents, Jannis; Lampert, Angelika Share Save
The Interaction of Aging and Cellular Stress Contributes to Pathogenesis in Mouse and Human Huntington Disease Neurons Machiela, Emily; Jeloka, Ritika; Caron, Nicholas S.; Mehta, Shagun; Schmidt, Mandi E.; Baddeley, Helen J. E.; Tom, Colton M.; Polturi, Nalini; Xie, Yuanyun; Mattis, Virginia B.; Hayden, Michael R.; Southwell, Amber L. Share Save
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Bioenergetic deficits in Huntington's disease iPSC-derived neural cells and rescue with glycolytic metabolites Kedaigle, Amanda J.; Fraenkel, Ernest; Atwal, Ranjit S.; Wu, Min; Gusella, James F.; MacDonald, Marcy E.; Kaye, Julia A.; Finkbeiner, Steven; Mattis, Virginia B.; Tom, Colton M.; Svendsen, Clive; King, Alvin R.; Chen, Yumay; Stocksdale, Jennifer T.; Lim, Ryan G.; Casale, Malcolm; Wang, Ping H.; Thompson, Leslie M.; Akimov, Sergey S.; Ratovitski, Tamara; Arbez, Nicolas; Ross, Christopher A. Share Save
A patient-derived cellular model for Huntington's disease reveals phenotypes at clinically relevant CAG lengths Hung, Claudia Lin-Kar; Maiuri, Tamara; Bowie, Laura Erin; Gotesman, Ryan; Son, Susie; Falcone, Mina; Giordano, James Victor; Gillis, Tammy; Mattis, Virginia; Lau, Trevor; Kwan, Vickie; Wheeler, Vanessa; Schertzer, Jonathan; Singh, Karun; Truant, Ray Share Save
Inducible Expression of GDNF in Transplanted iPSC-Derived Neural Progenitor Cells Akhtar, Aslam Abbasi; Gowing, Genevieve; Kobritz, Naomi; Savinoff, Steve E.; Garcia, Leslie; Saxon, David; Cho, Noell; Kim, Gibum; Tom, Colton M.; Park, Hannah; Lawless, George; Shelley, Brandon C.; Mattis, Virginia B.; Breunig, Joshua J.; Svendsen, Clive N. Share Save
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HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity Mattis, Virginia B.; Tom, Colton; Akimov, Sergey; Saeedian, Jasmine; Ostergaard, Michael E.; Southwell, Amber L.; Doty, Crystal N.; Ornelas, Loren; Sahabian, Anais; Lenaeus, Lindsay; Mandefro, Berhan; Sareen, Dhruv; Arjomand, Jamshid; Hayden, Michael R.; Ross, Christopher A.; Svendsen, Clive N. Share Save
Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease Lu, Xiao-Hong; Mattis, Virginia B.; Wang, Nan; Al-Ramahi, Ismael; van den Berg, Nick; Fratantoni, Silvina A.; Waldvogel, Henry; Greiner, Erin; Osmand, Alex; Elzein, Karla; Xiao, Jingbo; Dijkstra, Sipke; de Pril, Remko; Vinters, Harry V.; Faull, Richard; Signer, Ethan; Kwak, Seung; Marugan, Juan J.; Botas, Juan; Fischer, David F.; Svendsen, Clive N.; Munoz-Sanjuan, Ignacio; Yang, X. William Share Save
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