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Verification of In Vivo Estrogenic Activity for Four Per- and Polyfluoroalkyl Substances (PFAS) Identified as Estrogen Receptor Agonists via New Approach Methodologies Villeneuve, Daniel L.; Blackwell, Brett R.; Cavallin, Jenna E.; Collins, Jacob; Hoang, John X.; Hofer, Rachel N.; Houck, Keith A.; Jensen, Kathleen M.; Kahl, Michael D.; Kutsi, Robin N.; Opseth, Anne S.; Rodriguez, Kelvin J. Santana; Schaupp, Christopher; Stacy, Emma H.; Ankley, Gerald T. Share Save
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Comprehensive assessment of NR ligand polypharmacology by a multiplex reporter NR assay Medvedev, Alexander; Moeser, Matt; Medvedeva, Liubov; Martsen, Elena; Granick, Alexander; Raines, Lydia; Gorman, Kristen; Lin, Benjamin; Zeng, Ming; Houck, Keith A.; Makarov, Sergei S. Share Save
A Roadmap to the Structure-Related Metabolism Pathways of Per- and Polyfluoroalkyl Substances in the Early Life Stages of Zebrafish (Danio rerio) Han, Jiajun; Gu, Wen; Barrett, Holly; Yang, Diwen; Tang, Song; Sun, Jianxian; Liu, Jiabao; Krause, Henry M.; Houck, Keith A.; Peng, Hui Share Save
Quantitative Chemical Proteomics Reveals Interspecies Variations on Binding Schemes of L-FABP with Perfluorooctanesulfonate Han, Jiajun; Fu, Jesse; Sun, Jianxian; Hall, David Ross; Yang, Diwen; Blatz, Donovan; Houck, Keith; Ng, Carla; Doering, Jon; LaLone, Carlie; Peng, Hui Share Save
Bioactivity profiling of per- and polyfluoroalkyl substances (PFAS) identifies potential toxicity pathways related to molecular structure Houck, Keith A.; Patlewicz, Grace; Richard, Ann M.; Williams, Antony J.; Shobair, Mahmoud A.; Smeltz, Marci; Clifton, M. Scott; Wetmore, Barbara; Medvedev, Alex; Makarov, Sergei Share Save
Characterisation and validation of an in vitro transactivation assay based on the 22Rv1/MMTV_GR-KO cell line to detect human androgen receptor agonists and antagonists Park, Yooheon; Jung, Da-Woon; Milcamps, Anne; Takeyoshi, Masahiro; Jacobs, Miriam N.; Houck, Keith A.; Ono, Atsushi; Bovee, Toine F. H.; Browne, Patience; Delrue, Nathalie; Kang, YunSook; Lee, Hee-Seok Share Save
High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures Franzosa, Jill A.; Bonzo, Jessica A.; Jack, John; Baker, Nancy C.; Kothiya, Parth; Witek, Rafal P.; Hurban, Patrick; Siferd, Stephen; Hester, Susan; Shah, Imran; Ferguson, Stephen S.; Houck, Keith A.; Wambaugh, John F. Share Save
The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology Richard, Ann M.; Huang, Ruili; Waidyanatha, Suramya; Shinn, Paul; Collins, Bradley J.; Thillainadarajah, Inthirany; Grulke, Christopher M.; Williams, Antony J.; Lougee, Ryan R.; Judson, Richard S.; Houck, Keith A.; Shobair, Mahmoud; Yang, Chihae; Rathman, James F.; Yasgar, Adam; Fitzpatrick, Suzanne C.; Simeonov, Anton; Thomas, Russell S.; Crofton, Kevin M.; Paules, Richard S.; Bucher, John R.; Austin, Christopher P.; Kavlock, Robert J.; Tice, Raymond R. Share Save
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The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them Smith, Martyn T.; Guyton, Kathryn Z.; Kleinstreuer, Nicole; Borrel, Alexandre; Cardenas, Andres; Chiu, Weihsueh A.; Felsher, Dean W.; Gibbons, Catherine F.; Goodson, William H., III; Houck, Keith A.; Kane, Agnes B.; La Merrill, Michele A.; Lebrec, Herve; Lowe, Leroy; McHale, Cliona M.; Minocherhomji, Sheroy; Rieswijk, Linda; Sandy, Martha S.; Sone, Hideko; Wang, Amy; Zhang, Luoping; Zeise, Lauren; Fielden, Mark Share Save
Harmonized Cross-Species Assessment of Endocrine and Metabolic Disruptors by Ecotox FACTORIAL Assay Medvedev, Alexander V.; Medvedeva, Lyubov A.; Martsen, Elena; Moeser, Mathew; Gorman, Kristen L.; Lin, Benjamin; Blackwell, Brett; Villeneuve, Daniel L.; Houck, Keith A.; Crofton, Kevin M.; Makarov, Sergei S. Share Save
Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity (vol 174, pg 189, 2020) Zurlinden, Todd J.; Saili, Katerine S.; Rush, Nathaniel; Kothiya, Parth; Judson, Richard S.; Houck, Keith A.; Hunter, E. Sidney; Baker, Nancy C.; Palmer, Jessica A.; Thomas, Russell S.; Knudsen, Thomas B. Share Save
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Nontarget Screening of Per- and Polyfluoroalkyl Substances Binding to Human Liver Fatty Acid Binding Protein Yang, Diwen; Han, Jiajun; Hall, David Ross; Sun, Jianxian; Fu, Jesse; Kutarna, Steven; Houck, Keith A.; LaLone, Carlie A.; Doering, Jon A.; Ng, Carla A.; Peng, Hui Share Save
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Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity Zurlinden, Todd J.; Saili, Katerine S.; Rush, Nathaniel; Kothiya, Parth; Judson, Richard S.; Houck, Keith A.; Hunter, E. Sidney; Baker, Nancy C.; Palmer, Jessica A.; Thomas, Russell S.; Knudsen, Thomas B. Share Save
Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library Paul-Friedman, Katie; Martin, Matt; Crofton, Kevin M.; Hsu, Chia-Wen; Sakamuru, Srilatha; Zhao, Jinghua; Xia, Menghang; Huang, Ruili; Stavreva, Diana A.; Soni, Vikas; Varticovski, Lyuba; Raziuddin, Razi; Hager, Gordon L.; Houck, Keith A. Share Save
Methods for evaluating variability in human health dose-response characterization Axelrad, Daniel A.; Setzer, R. Woodrow; Bateson, Thomas F.; DeVito, Michael; Dzubow, Rebecca C.; Fitzpatrick, Julie W.; Frame, Alicia M.; Hogan, Karen A.; Houck, Keith; Stewart, Michael Share Save
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