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Memantine treatment in individuals with GRIN gain-of-function variants is associated with improvements in behavior, development, and seizure frequency Karnstedt, Maike; Perszyk, Riley E.; Myers, Scott J.; Mcdaniels, Ellington; Somorai, Marta; Borggraefe, Ingo; Veenma, Danielle C. M.; Schoonjans, An-sofie; Striano, Pasquale; Fantaneanu, Tadeu A.; Syrbe, Steffen; Park, Kristen; Chen, Wenjuan; Yuan, Hongjie; Traynelis, Stephen F.; Benke, Timothy A.; Lemke, Johannes R.; Krey, Ilona Share Save
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De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor Xu, Yuchen; Song, Rui; Perszyk, Riley E.; Chen, Wenjuan; Kim, Sukhan; Park, Kristen L.; Allen, James P.; Nocilla, Kelsey A.; Zhang, Jing; Xiangwei, Wenshu; Tankovic, Anel; McDaniels, Ellington D.; Sheikh, Rehan; Mizu, Ruth K.; Karamchandani, Manish M.; Hu, Chun; Kusumoto, Hirofumi; Pecha, Joseph; Cappuccio, Gerarda; Gaitanis, John; Sullivan, Jennifer; Shashi, Vandana; Petrovski, Slave; Jauss, Robin-Tobias; Lee, Hyun Kyung; Bozarth, Xiuhua; Lynch, David R.; Helbig, Ingo; Pierson, Tyler Mark; Boerkoel, Cornelius F.; Myers, Scott J.; Lemke, Johannes R.; Benke, Timothy A.; Yuan, Hongjie; Traynelis, Stephen F. Share Save
Clinical features, functional consequences, and rescue pharmacology of missense GRID1 and GRID2 human variants Allen, James P.; Garber, Kathryn B.; Perszyk, Riley; Khayat, Cara T.; Kell, Steven A.; Kaneko, Maki; Quindipan, Catherine; Saitta, Sulagna; Ladda, Roger L.; Hewson, Stacy; Inbar-Feigenberg, Michal; Prasad, Chitra; Prasad, Asuri N.; Olewiler, Leah; Mu, Weiyu; Rosenthal, Liana S.; Scala, Marcello; Striano, Pasquale; Zara, Federico; McCullock, Tyler W.; Jauss, Robin-Tobias; Lemke, Johannes R.; MacLean, David M.; Zhu, Cheng; Yuan, Hongjie; Myers, Scott J.; Traynelis, Stephen F. Share Save
Clinical and functional consequences of GRIA variants in patients with neurological diseases XiangWei, Wenshu; Perszyk, Riley E.; Liu, Nana; Xu, Yuchen; Bhattacharya, Subhrajit; Shaulsky, Gil H.; Smith-Hicks, Constance; Fatemi, Ali; Fry, Andrew E.; Chandler, Kate; Wang, Tao; Vogt, Julie; Cohen, Julie S.; Paciorkowski, Alex R.; Poduri, Annapurna; Zhang, Yuehua; Wang, Shuang; Wang, Yuping; Zhai, Qiongxiang; Fang, Fang; Leng, Jie; Garber, Kathryn; Myers, Scott J.; Jauss, Robin-Tobias; Park, Kristen L.; Benke, Timothy A.; Lemke, Johannes R.; Yuan, Hongjie; Jiang, Yuwu; Traynelis, Stephen F. Share Save
De novo CLPTM1 variants with reduced GABAAR current response in patients with epilepsy Liu, Nana; Li, Jinliang; Gao, Kai; Perszyk, Riley E.; Zhang, Jing; Wang, Jingmin; Wu, Ye; Jenkins, Andrew; Yuan, Hongjie; Traynelis, Stephen F.; Jiang, Yuwu Share Save
Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor D'Erasmo, Michael P.; Akins, Nicholas S.; Ma, Peipei; Jing, Yao; Swanger, Sharon A.; Sharma, Savita K.; Bartsch, Perry W.; Menaldino, David S.; Arcoria, Paul J.; Bui, Thi-Thien; Pons-Bennaceur, Alexandre; Le, Phuong; Allen, James P.; Ullman, Elijah Z.; Nocilla, Kelsey A.; Zhang, Jing; Perszyk, Riley E.; Kim, Sukhan; Acker, Timothy M.; Taz, Azmain; Burton, Samantha L.; Coe, Kevin; Fritzemeier, Russell G.; Burnashev, Nail; Yuan, Hongjie; Liotta, Dennis C.; Traynelis, Stephen F. Share Save
Classification of missense variants in the N-methyl-d-aspartate receptor GRIN gene family as gain- or loss-of-function Myers, Scott J.; Yuan, Hongjie; Perszyk, Riley E.; Zhang, Jing; Kim, Sukhan; Nocilla, Kelsey A.; Allen, James P.; Bain, Jennifer M.; Lemke, Johannes R.; Lal, Dennis; Benke, Timothy A.; Traynelis, Stephen F. Share Save
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Functional effects of disease-associated variants reveal that the S1-M1 linker of the NMDA receptor critically controls channel opening Xie, Lingling; McDaniel, Miranda J.; Perszyk, Riley E.; Kim, Sukhan; Cappuccio, Gerarda; Shapiro, Kevin A.; Munoz-Cabello, Beatriz; Sanchez-Lara, Pedro A.; Grand, Katheryn; Zhang, Jing; Nocilla, Kelsey A.; Sheikh, Rehan; Armengol, Lluis; Romano, Roberta; Pierson, Tyler Mark; Yuan, Hongjie; Myers, Scott J.; Traynelis, Stephen F. Share Save
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The GluN2A Subunit of the NMDA Receptor Modulates the Rate of Functional Maturation in Parvalbumin-positive Interneurons Camp, Chad R.; Shapiro, Lindsey; Vlachos, Anna; Perszyk, Riley E.; Shariatzadeh, Nima; White, Jacob; Sanchez, Russell; Koh, Sookyong; Escayg, Andrew; McBain, Christopher Share Save
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Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels Hansen, Kasper B.; Wollmuth, Lonnie P.; Bowie, Derek; Furukawa, Hiro; Menniti, Frank S.; Sobolevsky, Alexander, I; Swanson, Geoffrey T.; Swanger, Sharon A.; Greger, Ingo H.; Nakagawa, Terunaga; McBain, Chris J.; Jayaraman, Vasanthi; Low, Chian-Ming; Dell'Acqua, Mark L.; Diamond, Jeffrey S.; Camp, Chad R.; Perszyk, Riley E.; Yuan, Hongjie; Traynelis, Stephen F. Share Save
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