Hongjie Yuan - Publications, H-index & Citations

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Hongjie Yuan

Emory University

44H-index

166Paper Count

1.0WCitation Count

Published Papers 70

Publication Date

A Subunit-Selective Negative Allosteric Modulator of GluN1/GluN3A Glycine-Activated Receptor

Molecular Pharmacology

IF3

2026-01-29

OAAI

Leon Jacobs; TrangKimberly T. Nguyen; Adam McCallum; Matt P. Epplin; Riley E. Perszyk; Scott J. Myers; Ken Liu; Yanli Yang; Aletta E. Van der Westhuyzen; Kelsey A. Nocilla; James Allen; Elijah Z. Ullman; Ding Liu; Yufei Du; Hongjie Yuan; Dennis C. Liotta; Stephen F. Traynelis

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Radiosynthesis and Evaluation of 18F-Labeled Deuterated Radioligand for Positron Emission Tomography Imaging of Cholesterol 24-Hydroxylase

ACS Medicinal Chemistry Letters

IF4

2026-01-20

OAAI

Yinlong Li; Zhendong Song; Haofeng Shi; Taoqian Zhao; Jiahui Chen; Xin Zhou; Qilong Hu; Xiaoyan Li; Lingxin Meng; Ruihu Song; Zhenkun Sun; Chongjiao Li; Achi Haider; Hongjie Yuan; Steven H. Liang

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Memantine treatment in individuals with GRIN gain-of-function variants is associated with improvements in behavior, development, and seizure frequency

Epilepsia

IF6.6

2026-01-01

OAAI

Karnstedt, Maike; Perszyk, Riley E.; Myers, Scott J.; Mcdaniels, Ellington; Somorai, Marta; Borggraefe, Ingo; Veenma, Danielle C. M.; Schoonjans, An-sofie; Striano, Pasquale; Fantaneanu, Tadeu A.; Syrbe, Steffen; Park, Kristen; Chen, Wenjuan; Yuan, Hongjie; Traynelis, Stephen F.; Benke, Timothy A.; Lemke, Johannes R.; Krey, Ilona

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Development of Novel 18F-Labeled Selective Orexin-2 Receptor Radioligands for Positron Emission Tomography

ACS Pharmacology & Translational Science

IF3.7

2025-10-11

OAAI

Jian Rong; Chunyu Zhao; Ahmad F. Chaudhary; Jiahui Chen; Yinlong Li; Xin Zhou; Zhendong Song; Zhenkun Sun; Yabiao Gao; Siyan Feng; Taoqian Zhao; Qi-Long Hu; Chongjiao Li; Jimmy Patel; Hongjie Yuan; Achi Haider; Steven H. Liang

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Enhancement of hippocampal interneuron excitability by NMDA receptor positive allosteric modulation

The Journal of Physiology

IF0

2025-10-06

OAAI

Hao Xing; Tue G. Banke; Lu Zhang; Kuai Yu; Chad R. Camp; Russell G. Fritzemeier; Nicholas S. Akins; Srinu Paladugu; Paul J. Arcoria; Brian R. Brady; Olga Prikhodko; Matthew J. Kennedy; Dennis C. Liotta; Hongjie Yuan; Stephen F. Traynelis

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Inhibition of GluN2B-containing N-methyl-D-aspartate receptors by radiprodil

Brain

IF11.7

2025-09-25

OAAI

Tue G Banke; Michael C Regan; Riley E Perszyk; Lu Zhang; Hao Xing; Jiahui Chen; Sehoon Won; Noriko Simorowski; Eva S Diaz; Sukhan Kim; Rui Song; Jian Rong; Xin Zhou; Ahmad F Chaudhary; Jing Zhang; John F Traynelis; Ellington D McDaniels; Karolina Nitsche; Steve Roache; Christopher S Raymond; Chian-Ming Low; Scott J Myers; Katherine W Roche; Steven H Liang; Stephen F Traynelis; Hiro Furukawa; Hongjie Yuan

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Synaptic dysregulation in a mouse model of GRIN2D developmental and epileptic encephalopathy

BRAIN

IF11.7

2025-09-01

PREAI

Teoh, Jiajie; Simko, Jane; Camp, Chad R.; Liu, Christine J.; Wang, Wanqi; Williams, Damian J.; Ma, Liang; Soundararajan, Divyalakshmi; Martin, Caryn; Taylor, Noah K.; Francois, Ekniel; Petri, Sabrina; Kanber, Ayla; Ravichandra, Aishwarya; Pero, Maria Elena; Bartolini, Francesca; Swayne, Theresa C.; Lutz, Cathleen M.; Zuberi, Aamir; Rubinstein, Moran; Hausman-Kedem, Moran; Yuan, Hongjie; Gelinas, Jennifer N.; Sands, Tristan T.; Harper, Scott Q.; Traynelis, Stephen F.; Makinson, Christopher D.; Frankel, Wayne N.

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Selective enhancement of the interneuron network and gamma-band power via GluN2C/GluN2D NMDA receptor potentiation

physiology

IF0

2025-06-25

PREAI

Chad R. Camp; Tue G. Banke; Hao Xing; Kuai Yu; Riley E. Perszyk; Matthew P. Epplin; Nicholas S. Akins; Jing Zhang; Tim A. Benke; Hongjie Yuan

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Development of a Novel 18F-Labeled Radioligand for Imaging Cholesterol 24-Hydroxylase with Positron Emission Tomography

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

IF3.7

2025-02-24

OAAI

Rong, J; Zhao, CY; Chaudhary, AF; Chen, JH; Zhou, X; Zhang, K; Song, ZD; Sun, ZK; Gao, YB; Zhang, Z; Feng, SY; Collier, TL; Yuan, HJ; Patel, JS; Haider, A; Li, YL; Liang, SH

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NGF-releasing Prussian blue nanoparticles for nerve injury repair of lumbar disc herniation

FRONTIERS IN CHEMISTRY

IF4.2

2024-12-18

OAAI

Tang, Xiaoxing; Sun, Xin; Ji, Yun; Huang, Xuehua; Xiao, Shilin; Zhou, Yanjing; Ma, Ke; Yuan, Hongjie

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Ligand distances as key predictors of pathogenicity and function in NMDA receptors

HUMAN MOLECULAR GENETICS

IF3.2

2024-11-13

OAAI

Montanucci, Ludovica; Bruenger, Tobias; Bhattarai, Nisha; Bosselmann, Christian M.; Kim, Sukhan; Allen, James P.; Zhang, Jing; Kloeckner, Chiara; Krey, Ilona; Fariselli, Piero; May, Patrick; Lemke, Johannes R.; Myers, Scott J.; Yuan, Hongjie; Traynelis, Stephen F.; Lal, Dennis

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Development of a Candidate 11C-Labeled Selective Phosphodiesterase 1 Radioligand for Positron Emission Tomography

ACS OMEGA

IF4.3

2024-10-21

OAAI

Rong, Jian; Yamasaki, Tomoteru; Chen, Jiahui; Kumata, Katsushi; Zhao, Chunyu; Fujinaga, Masayuki; Hu, Kuan; Mori, Wakana; Zhang, Yiding; Xie, Lin; Chaudhary, Ahmad F.; Zhou, Xin; Zhang, Wei; Gao, Yabiao; Zhang, Kuo; Patel, Jimmy S.; Song, Zhendong; Collier, Thomas L.; Yuan, Hongjie; Ran, Chongzhao; Haider, Ahmed; Li, Yinlong; Zhang, Ming-Rong; Liang, Steven

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Channel-Blind Joint Source-Channel Coding for Wireless Image Transmission

SENSORS

IF3.5

2024-06-20

OAAI

Yuan, Hongjie; Xu, Weizhang; Wang, Yuhuan; Wang, Xingxing

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Postovulatory Aging of Mouse Oocytes Impairs Offspring Behavior by Causing Oxidative Stress and Damaging Mitochondria

CELLS

IF5.2

2024-04-28

OAAI

Xu, Ming-Tao; Zhang, Min; Wang, Guo-Liang; Gong, Shuai; Luo, Ming-Jiu; Zhang, Jie; Yuan, Hong-Jie; Tan, Jing-He

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De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2024-03-28

OAAI

Xu, Yuchen; Song, Rui; Perszyk, Riley E.; Chen, Wenjuan; Kim, Sukhan; Park, Kristen L.; Allen, James P.; Nocilla, Kelsey A.; Zhang, Jing; Xiangwei, Wenshu; Tankovic, Anel; McDaniels, Ellington D.; Sheikh, Rehan; Mizu, Ruth K.; Karamchandani, Manish M.; Hu, Chun; Kusumoto, Hirofumi; Pecha, Joseph; Cappuccio, Gerarda; Gaitanis, John; Sullivan, Jennifer; Shashi, Vandana; Petrovski, Slave; Jauss, Robin-Tobias; Lee, Hyun Kyung; Bozarth, Xiuhua; Lynch, David R.; Helbig, Ingo; Pierson, Tyler Mark; Boerkoel, Cornelius F.; Myers, Scott J.; Lemke, Johannes R.; Benke, Timothy A.; Yuan, Hongjie; Traynelis, Stephen F.

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Clinical features, functional consequences, and rescue pharmacology of missense GRID1 and GRID2 human variants

HUMAN MOLECULAR GENETICS

IF3.2

2023-11-07

OAAI

Allen, James P.; Garber, Kathryn B.; Perszyk, Riley; Khayat, Cara T.; Kell, Steven A.; Kaneko, Maki; Quindipan, Catherine; Saitta, Sulagna; Ladda, Roger L.; Hewson, Stacy; Inbar-Feigenberg, Michal; Prasad, Chitra; Prasad, Asuri N.; Olewiler, Leah; Mu, Weiyu; Rosenthal, Liana S.; Scala, Marcello; Striano, Pasquale; Zara, Federico; McCullock, Tyler W.; Jauss, Robin-Tobias; Lemke, Johannes R.; MacLean, David M.; Zhu, Cheng; Yuan, Hongjie; Myers, Scott J.; Traynelis, Stephen F.

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Clinical and functional consequences of GRIA variants in patients with neurological diseases

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2023-11-03

OAAI

XiangWei, Wenshu; Perszyk, Riley E.; Liu, Nana; Xu, Yuchen; Bhattacharya, Subhrajit; Shaulsky, Gil H.; Smith-Hicks, Constance; Fatemi, Ali; Fry, Andrew E.; Chandler, Kate; Wang, Tao; Vogt, Julie; Cohen, Julie S.; Paciorkowski, Alex R.; Poduri, Annapurna; Zhang, Yuehua; Wang, Shuang; Wang, Yuping; Zhai, Qiongxiang; Fang, Fang; Leng, Jie; Garber, Kathryn; Myers, Scott J.; Jauss, Robin-Tobias; Park, Kristen L.; Benke, Timothy A.; Lemke, Johannes R.; Yuan, Hongjie; Jiang, Yuwu; Traynelis, Stephen F.

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Loss of Grin2a causes a transient delay in the electrophysiological maturation of hippocampal parvalbumin interneurons

COMMUNICATIONS BIOLOGY

IF5.1

2023-09-19

OAAI

Camp, Chad R.; Vlachos, Anna; Kloeckner, Chiara; Krey, Ilona; Banke, Tue G.; Shariatzadeh, Nima; Ruggiero, Sarah M.; Galer, Peter; Park, Kristen L.; Caccavano, Adam; Kimmel, Sarah; Yuan, Xiaoqing; Yuan, Hongjie; Helbig, Ingo; Benke, Tim A.; Lemke, Johannes R.; Pelkey, Kenneth A.; McBain, Chris J.; Traynelis, Stephen F.

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De novo CLPTM1 variants with reduced GABAAR current response in patients with epilepsy

EPILEPSIA

IF6.6

2023-08-30

OAAI

Liu, Nana; Li, Jinliang; Gao, Kai; Perszyk, Riley E.; Zhang, Jing; Wang, Jingmin; Wu, Ye; Jenkins, Andrew; Yuan, Hongjie; Traynelis, Stephen F.; Jiang, Yuwu

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Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor

ACS CHEMICAL NEUROSCIENCE

IF3.9

2023-08-11

OAAI

D'Erasmo, Michael P.; Akins, Nicholas S.; Ma, Peipei; Jing, Yao; Swanger, Sharon A.; Sharma, Savita K.; Bartsch, Perry W.; Menaldino, David S.; Arcoria, Paul J.; Bui, Thi-Thien; Pons-Bennaceur, Alexandre; Le, Phuong; Allen, James P.; Ullman, Elijah Z.; Nocilla, Kelsey A.; Zhang, Jing; Perszyk, Riley E.; Kim, Sukhan; Acker, Timothy M.; Taz, Azmain; Burton, Samantha L.; Coe, Kevin; Fritzemeier, Russell G.; Burnashev, Nail; Yuan, Hongjie; Liotta, Dennis C.; Traynelis, Stephen F.

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Research Directions