Alexandra L. Joyner - Publications, H-index & Citations

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Alexandra L. Joyner

memorial sloan kettering cancer center

99H-index

313Paper Count

3.7WCitation Count

Published Papers 77

Publication Date

PTEN restrains SHH medulloblastoma growth through cell autonomous and nonautonomous mechanisms

eLife

IF0

2026-04-01

PREAI

Lao, Zhimin; El Nagar, Salsabiel; Liang, Yinwen; Stephen, Daniel; Joyner, Alexandra L.

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Transcription factors SP5 and SP8 drive primary cilia formation in mammalian embryos

Science

IF45.8

2025-08-28

PREAI

Yinwen Liang; Richard Koche; Ravindra B. Chalamalasetty; Daniel N. Stephen; Mark W. Kennedy; Zhimin Lao; Yunong Pang; Ying-Yi Kuo; Moonsup Lee; Francisco Pereira Lobo; Xiaofeng Huang; Anna-Katerina Hadjantonakis; Terry P. Yamaguchi; Kathryn V. Anderson; Alexandra L. Joyner

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Coenzyme Q headgroup intermediates can ameliorate a mitochondrial encephalopathy

Nature

IF48.5

2025-07-09

OAAI

Guangbin Shi; Claire Miller; Sota Kuno; Alejandro G. Rey Hipolito; Salsabiel El Nagar; Giulietta M. Riboldi; Megan Korn; Wyatt C. Tran; Zixuan Wang; Lia Ficaro; Tao Lin; Quentin Spillier; Begoña Gamallo-Lana; Drew R. Jones; Matija Snuderl; Soomin C. Song; Adam C. Mar; Alexandra L. Joyner; Roy V. Sillitoe; Robert S. Banh; Michael E. Pacold

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Cerebellar output neurons can impair non-motor behaviors by altering development of extracerebellar connectivity

NATURE COMMUNICATIONS

IF15.7

2025-02-21

OAAI

Lee, Andrew S.; Arefin, Tanzil M.; Gubanova, Alina; Stephen, Daniel N.; Liu, Yu; Lao, Zhimin; Krishnamurthy, Anjana; Garcia, Natalia V. De Marcovv; Heck, Detlef H.; Zhang, Jiangyang; Rajadhyaksha, Anjali M.; Joyner, Alexandra L.

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Conserved roles of engrailed: patterning tissues and specifying cell types

DEVELOPMENT

IF3.6

2024-12-13

PREAI

Joyner, Alexandra L.; Ortigao-Farias, Joao Ramalho; Kornberg, Thomas

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Engrailed transcription factors direct excitatory cerebellar neuron diversity and survival

DEVELOPMENT

IF3.6

2024-07-26

OAAI

Krishnamurthy, Anjana; Lee, Andrew S.; Bayin, N. Sumru; Stephen, Daniel N.; Nasef, Olivia; Lao, Zhimin; Joyner, Alexandra L.

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Childhood cancer mutagenesis caused by transposase-derived PGBD5

SCIENCE ADVANCES

IF12.5

2024-03-22

OAAI

Yamada, Makiko; Keller, Ross R.; Gutierrez, Rodrigo Lopez; Cameron, Daniel; Suzuki, Hiromichi; Sanghrajka, Reeti; Vaynshteyn, Jake; Gerwin, Jeffrey; Maura, Francesco; Hooper, William; Shah, Minita; Robine, Nicolas; Demarest, Phillip; Bayin, N. Sumru; Zapater, Luz Jubierre; Reed, Casie; Hebert, Steven; Masilionis, Ignas; Chaligne, Ronan; Socci, Nicholas D.; Taylor, Michael D.; Kleinman, Claudia L.; Joyner, Alexandra L.; Raju, G. Praveen; Kentsis, Alex

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Cell division angle predicts the level of tissue mechanics that tune the amount of cerebellar folding

DEVELOPMENT

IF3.6

2024-02-13

OAAI

Cook, Amber G.; Bishop, Taylor, V; Crowe, Hannah R.; Stevens, Daniel N.; Reine, Lauren; Joyner, Alexandra L.; Lawton, Andrew K.

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The exon 8-containing prosaposin gene splice variant is dispensable for mouse development, lysosomal function, and secretion

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Cohen, T; Auerbach, W; Ravid, L; Bodennec, J; Fein, A; Futerman, AH; Joyner, AL; Horowitz, M

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Deletion of mouse Rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

133

OAAI

Hopkins, KM; Auerbach, W; Wang, XY; Hande, MP; Hang, HY; Wolgemuth, DJ; Joyner, AL; Lieberman, HB

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Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

567

OAAI

Pan, Y; Bai, CYB; Joyner, AL; Wang, BL

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Cerebellum lineage allocation, morphogenesis and repair: impact of interplay amongst cells

DEVELOPMENT

IF3.6

2022-09-29

OAAI

Joyner, Alexandra L.; Bayin, N. Sumru

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Rapid and efficient degradation of endogenous proteins in vivo identifies stage-specific roles of RNA Pol II pausing in mammalian development

DEVELOPMENTAL CELL

IF8.7

2022-04-01

OAAI

Abuhashem, Abderhman; Lee, Andrew S.; Joyner, Alexandra L.; Hadjantonakis, Anna-Katerina

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Injury-induced ASCL1 expression orchestrates a transitory cell state required for repair of the neonatal cerebellum

SCIENCE ADVANCES

IF12.5

2021-12-10

OAAI

Bayin, N. Sumru; Mizrak, Dogukan; Stephen, Daniel N.; Lao, Zhimin; Sims, Peter A.; Joyner, Alexandra L.

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CSF1R inhibition depletes tumor-associated macrophages and attenuates tumor progression in a mouse sonic Hedgehog-Medulloblastoma model

ONCOGENE

IF7.3

2020-11-06

OAAI

Tan, I-Li; Arifa, Raquel Duque Nascimento; Rallapalli, Harikrishna; Kana, Veronika; Lao, Zhimin; Sanghrajka, Reeti Mayur; Sumru Bayin, N.; Tanne, Antoine; Wojcinski, Alexandre; Korshunov, Andrey; Bhardwaj, Nina; Merad, Miriam; Turnbull, Daniel H.; Lafaille, Juan J.; Joyner, Alexandra L.

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Single-Cell Profiling and SCOPE-Seq Reveal Lineage Dynamics of Adult Ventricular-Subventricular Zone Neurogenesis and NOTUM as a Key Regulator

CELL REPORTS

IF6.9

2020-06-01

OAAI

Mizrak, Dogukan; Bayin, N. Sumru; Yuan, Jinzhou; Liu, Zhouzerui; Suciu, Radu M.; Niphakis, Micah J.; Nhi Ngo; Lum, Kenneth M.; Cravatt, Benjamin F.; Joyner, Alexandra L.; Sims, Peter A.

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Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2020-03-20

OAAI

Lehmann, Guillermo L.; Hanke-Gogokhia, Christin; Hu, Yang; Bareja, Rohan; Salfati, Zelda; Ginsberg, Michael; Nolan, Daniel J.; Mendez-Huergo, Santiago P.; Dalotto-Moreno, Tomas; Wojcinski, Alexandre; Ochoa, Francisca; Zeng, Shemin; Cerliani, Juan P.; Panagis, Lampros; Zager, Patrick J.; Mullins, Robert F.; Ogura, Shuntaro; Lutty, Gerard A.; Bang, Jakyung; Zippin, Jonathan H.; Romano, Carmelo; Rabinovich, Gabriel A.; Elemento, Olivier; Joyner, Alexandra L.; Rafii, Shahin; Rodriguez-Boulan, Enrique; Benedicto, Ignacio

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A collection of genetic mouse lines and related tools for inducible and reversible intersectional mis-expression

DEVELOPMENT

IF3.6

2020-01-01

OAAI

Ahmadzadeh, Elham; Bayin, N. Sumru; Qu, Xinli; Singh, Aditi; Madisen, Linda; Stephen, Daniel; Zeng, Hongkui; Joyner, Alexandra L.; Rosello-Diez, Alberto

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Cerebellar nuclei excitatory neurons regulate developmental scaling of presynaptic Purkinje cell number and organ growth

ELIFE

IF0

2019-11-19

OAAI

Willett, Ryan T.; Bayin, N. Sumru; Lee, Andrew S.; Krishnamurthy, Anjana; Wojcinski, Alexandre; Lao, Zhimin; Stephen, Daniel; Rosello-Diez, Alberto; Dauber-Decker, Katherine L.; Orvis, Grant D.; Wu, Zhuhao; Tessier-Lavigne, Marc; Joyner, Alexandra L.

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MEMRI-based imaging pipeline for guiding preclinical studies in mouse models of sporadic medulloblastoma

MAGNETIC RESONANCE IN MEDICINE

IF3

2019-08-12

OAAI

Rallapalli, Harikrishna; Tan, I-Li; Volkova, Eugenia; Wojcinski, Alexandre; Darwin, Benjamin C.; Lerch, Jason P.; Joyner, Alexandra L.; Turnbull, Daniel H.

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Research Directions