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COVID-19 progression and convalescence in common variable immunodeficiency patients show dysregulated adaptive immune responses and persistent type I interferon and inflammasome activation Rodriguez-Ubreva, Javier; Calafell-Segura, Josep; Calvillo, Celia L.; Keller, Baerbel; Ciudad, Laura; Handfield, Louis-Francois; de la Calle-fabregat, Carlos; Godoy-Tena, Gerard; Andres-Leon, Eduardo; Hoo, Regina; Porter, Tarryn; Prigmore, Elena; Hofmann, Maike; Decker, Annegrit; Martin, Javier; Vento-Tormo, Roser; Warnatz, Klaus; Ballestar, Esteban Share Save
NF-κB and TET2 promote macrophage reprogramming in hypoxia that overrides the immunosuppressive effects of the tumor microenvironment de la Calle-Fabregat, Carlos; Calafell-Segura, Josep; Gardet, Margaux; Dunsmore, Garett; Mulder, Kevin; Ciudad, Laura; Silvin, Aymeric; Moreno-Caceres, Joaquim; Corbi, angel L.; Munoz-Pinedo, Cristina; Michels, Judith; Gouy, Sebastien; Dutertre, Charles-Antoine; Rodriguez-Ubreva, Javier; Ginhoux, Florent; Ballestar, Esteban Share Save
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Epigenome profiling reveals aberrant DNA methylation signature in GATA2 deficiency Marin-Bejar, Oskar; Romero-Moya, Damia; Rodriguez-Ubreva, Javier; Distefano, Maximiliano; Lessi, Francesca; Aretini, Paolo; Liquori, Alessandro; Castano, Julio; Kozyra, Emilia; Kotmayer, Lili; Bueno, Clara; Cervera, Jose; Rodriguez-Gallego, Jose Carlos; Nomdedeu, Josep F.; Murillo-Sanjuan, Laura; Diaz de Heredia, Cristina; Perez-Martinez, Antonio; Lopez-Cadenas, Felix; Martinez-Laperche, Carolina; Dorado-Herrero, Nieves; Marco, Francisco M.; Prosper, Felipe; Menendez, Pablo; Valcarcel, David; Ballestar, Esteban; Bodor, Csaba; Bigas, Anna; Catala, Albert; Wlodarski, Marcin W.; Giorgetti, Alessandra Share Save
The synovial and blood monocyte DNA methylomes mirror prognosis, evolution, and treatment in early arthritis de la Calle-Fabregat, Carlos; Rodriguez-Ubreva, Javier; Ciudad, Laura; Ramirez, Julio; Celis, Raquel; Belen Azuaga, Ana; Cuervo, Andrea; Graell, Eduard; Perez-Garcia, Carolina; Diaz-Torne, Cesar; Salvador, Georgina; Gomez-Puerta, Jose A.; Haro, Isabel; Sanmarti, Raimon; Canete, Juan D.; Ballestar, Esteban Share Save
Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses Rodriguez-Ubreva, Javier; Arutyunyan, Anna; Bonder, Marc Jan; Del Pino-Molina, Lucia; Clark, Stephen J.; de la Calle-Fabregat, Carlos; Garcia-Alonso, Luz; Handfield, Louis-Francois; Ciudad, Laura; Andres-Leon, Eduardo; Krueger, Felix; Catala-Moll, Francesc; Rodriguez-Cortez, Virginia C.; Polanski, Krzysztof; Mamanova, Lira; van Dongen, Stijn; Kiselev, Vladimir Yu; Martinez-Saavedra, Maria T.; Heyn, Holger; Martin, Javier; Warnatz, Klaus; Lopez-Granados, Eduardo; Rodriguez-Gallego, Carlos; Stegle, Oliver; Kelsey, Gavin; Vento-Tormo, Roser; Ballestar, Esteban Share Save
Vitamin D receptor, STAT3, and TET2 cooperate to establish tolerogenesis Catala-Moll, Francesc; Ferrete-Bonastre, Anna G.; Godoy-Tena, Gerard; Morante-Palacios, Octavio; Ciudad, Laura; Barbera, Laura; Fondelli, Federico; Martinez-Caceres, Eva M.; Rodriguez-Ubreva, Javier; Li, Tianlu; Ballestar, Esteban Share Save
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Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reaction Catala-Moll, Francesc; Ferrete-Bonastre, Anna G.; Li, Tianlu; Weichenhan, Dieter; Lutsik, Pavlo; Ciudad, Laura; Alvarez-Prado, Angel F.; Rodriguez-Ubreva, Javier; Klemann, Christian; Speckmann, Carsten; Vilas-Zornoza, Amaya; Abolhassani, Hassan; Martinez-Gallo, Monica; Dieli-Crimi, Romina; Riviere, Jacques G.; Martin-Nalda, Andrea; Colobran, Roger; Soler-Palacin, Pere; Kracker, Sven; Hammarstrom, Lennart; Prosper, Felipe; Durandy, Anne; Grimbacher, Bodo; Plass, Christoph; Ballestar, Esteban Share Save
Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases Barturen, Guillermo; Babaei, Sepideh; Catala-Moll, Francesc; Martinez-Bueno, Manuel; Makowska, Zuzanna; Martorell-Marugan, Jordi; Carmona-Saez, Pedro; Toro-Dominguez, Daniel; Carnero-Montoro, Elena; Teruel, Maria; Kerick, Martin; Acosta-Herrera, Marialbert; Le Lann, Lucas; Jamin, Christophe; Rodriguez-Ubreva, Javier; Garcia-Gomez, Antonio; Kageyama, Jorge; Buttgereit, Anne; Hayat, Sikander; Mueller, Joerg; Lesche, Ralf; Hernandez-Fuentes, Maria; Juarez, Maria; Rowley, Tania; White, Ian; Maranon, Concepcion; Gomes Anjos, Tania; Varela, Nieves; Aguilar-Quesada, Rocio; Garrancho, Francisco Javier; Lopez-Berrio, Antonio; Rodriguez Maresca, Manuel; Navarro-Linares, Hector; Almeida, Isabel; Azevedo, Nancy; Brandao, Mariana; Campar, Ana; Faria, Raquel; Farinha, Fatima; Marinho, Antonio; Neves, Esmeralda; Tavares, Ana; Vasconcelos, Carlos; Trombetta, Elena; Montanelli, Gaia; Vigone, Barbara; Alvarez-Errico, Damiana; Li, Tianlu; Thiagaran, Divya; Blanco Alonso, Ricardo; Corrales Martinez, Alfonso; Genre, Fernanda; Lopez Mejias, Raquel; Gonzalez-Gay, Miguel A.; Remuzgo, Sara; Ubilla Garcia, Begona; Cervera, Ricard; Espinosa, Gerard; Rodriguez-Pinto, Ignasi; De Langhe, Ellen; Cremer, Jonathan; Lories, Rik; Belz, Doreen; Hunzelmann, Nicolas; Baerlecken, Niklas; Kniesch, Katja; Witte, Torsten; Lehner, Michaela; Stummvoll, Georg; Zauner, Michael; Aguirre-Zamorano, Maria Angeles; Barbarroja, Nuria; Castro-Villegas, Maria Carmen; Collantes-Estevez, Eduardo; de Ramon, Enrique; Diaz Quintero, Isabel; Escudero-Contreras, Alejandro; Fernandez Roldan, Maria Concepcion; Jimenez Gomez, Yolanda; Jimenez Moleon, Inmaculada; Lopez-Pedrera, Rosario; Ortega-Castro, Rafaela; Ortego, Norberto; Raya, Enrique; Artusi, Carolina; Gerosa, Maria; Meroni, Pier Luigi; Schioppo, Tommaso; De Groof, Aurelie; Ducreux, Julie; Lauwerys, Bernard; Maudoux, Anne-Lise; Cornec, Divi; Devauchelle-Pensec, Valerie; Jousse-Joulin, Sandrine; Jouve, Pierre-Emmanuel; Rouviere, Benedicte; Saraux, Alain; Simon, Quentin; Alvarez, Montserrat; Chizzolini, Carlo; Dufour, Aleksandra; Wynar, Donatienne; Balog, Attila; Bocskai, Marta; Deak, Magdolna; Dulic, Sonja; Kadar, Gabriella; Kovacs, Laszlo; Cheng, Qingyu; Gerl, Velia; Hiepe, Falk; Khodadadi, Laleh; Thiel, Silvia; de Rinaldis, Emanuele; Rao, Sambasiva; Benschop, Robert J.; Chamberlain, Chris; Dow, Ernst R.; Ioannou, Yiannis; Laigle, Laurence; Marovac, Jacqueline; Wojcik, Jerome; Renaudineau, Yves; Borghi, Maria Orietta; Frostegard, Johan; Martin, Javier; Beretta, Lorenzo; Ballestar, Esteban; McDonald, Fiona; Pers, Jacques-Olivier; Alarcon-Riquelme, Marta E. Share Save
Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease Garcia-Gomez, Antonio; Li, Tianlu; de la Calle-Fabregat, Carlos; Rodriguez-Ubreva, Javier; Ciudad, Laura; Catala-Moll, Francesc; Godoy-Tena, Gerard; Martin-Sanchez, Montserrat; San-Segundo, Laura; Muntion, Sandra; Morales, Xabier; Ortiz-de-Solorzano, Carlos; Oyarzabal, Julen; San Jose-Eneriz, Edurne; Esteller, Manel; Agirre, Xabier; Prosper, Felipe; Garayoa, Mercedes; Ballestar, Esteban Share Save
Sampling time-dependent artifacts in single-cell genomics studies Massoni-Badosa, Ramon; Iacono, Giovanni; Moutinho, Catia; Kulis, Marta; Palau, Nuria; Marchese, Domenica; Rodriguez-Ubreva, Javier; Ballestar, Esteban; Rodriguez-Esteban, Gustavo; Marsal, Sara; Aymerich, Marta; Colomer, Dolors; Campo, Elias; Julia, Antonio; Martin-Subero, Jose Ignacio; Heyn, Holger Share Save
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Impaired CpG Demethylation in Common Variable Immunodeficiency Associates With B Cell Phenotype and Proliferation Rate del Pino-Molina, Lucia; Rodriguez-Ubreva, Javier; Torres Canizales, Juan; Coronet-Diaz, Maria; Kulis, Marta; Martin-Subero, Jose, I; van der Burg, Miriam; Ballestar, Esteban; Lopez-Granados, Eduardo Share Save
Prostaglandin E2 Leads to the Acquisition of DNMT3A-Dependent Tolerogenic Functions in Human Myeloid-Derived Suppressor Cells Rodriguez-Ubreva, Javier; Catala-Moll, Francesc; Obermajer, Natasa; Alvarez-Errico, Damiana; Ramirez, Ricardo N.; Company, Carlos; Vento-Tormo, Roser; Moreno-Bueno, Gema; Edwards, Robert P.; Mortazavi, Ali; Kalinski, Pawel; Ballestar, Esteban Share Save
Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites Rodriguez-Cortez, Virginia C.; Martinez-Redondo, Paloma; Catala-Moll, Francesc; Rodriguez-Ubreva, Javier; Garcia-Gomez, Antonio; Poorani-Subramani, Ganesh; Ciudad, Laura; Hernando, Henar; Perez-Garcia, Arantxa; Company, Carlos; Urquiza, Jose M.; Ramiro, Almudena R.; Di Noia, Javier M.; Vaquero, Alejandro; Ballestar, Esteban Share Save
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TET2-and TDG-mediated changes are required for the acquisition of distinct histone modifications in divergent terminal differentiation of myeloid cells Garcia-Gomez, Antonio; Li, Tianlu; Kerick, Martin; Catala-Moll, Francesc; Comet, Natalia R.; Rodriguez-Ubreva, Javier; de la Rica, Lorenzo; Branco, Miguel R.; Martin, Javier; Ballestar, Esteban Share Save
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