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SaveThe Cyclic Imine Core Common to the Marine Macrocyclic Toxins Is Sufficient to Dictate Nicotinic Acetylcholine Receptor Antagonism
Bourne, Yves; Sulzenbacher, Gerlind; Chabaud, Laurent; Araoz, Romulo; Radic, Zoran; Conrod, Sandrine; Taylor, Palmer; Guillou, Catherine; Molgo, Jordi; Marchot, Pascale
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SaveThe cell polarity protein Vangl2 in the muscle shapes the neuromuscular synapse by binding to and regulating the tyrosine kinase MuSK
Boex, Myriam; Cottin, Steve; Halliez, Marius; Bauche, Stephanie; Buon, Celine; Sans, Nathalie; Montcouquiol, Mireille; Molgo, Jordi; Amar, Muriel; Ferry, Arnaud; Lemaitre, Megane; Rouche, Andree; Langui, Dominique; Baskaran, Asha; Fontaine, Bertrand; Messeant, Julien; Strochlic, Laure
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SaveFirst evidence that emerging pinnatoxin-G, a contaminant of shellfish, reaches the brain and crosses the placental barrier
Servent, Denis; Malgorn, Carole; Bernes, Mylene; Gil, Sophie; Simasotchi, Christelle; Herard, Anne-Sophie; Delzescaux, Thierry; Thai, Robert; Barbe, Peggy; Keck, Mathilde; Beau, Fabrice; Zakarian, Armen; Dive, Vincent; Molgo, Jordi
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SaveGuidance Level for Brevetoxins in French Shellfish
Arnich, Nathalie; Abadie, Eric; Amzil, Zouher; Dechraoui Bottein, Marie-Yasmine; Comte, Katia; Chaix, Estelle; Delcourt, Nicolas; Hort, Vincent; Mattei, Cesar; Molgo, Jordi; Le Garrec, Raphaele
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SaveScalable Total Synthesis, IP3R Inhibitory Activity of Desmethylxestospongin B, and Effect on Mitochondrial Function and Cancer Cell Survival
Podunavac, Masa; Mailyan, Artur K.; Jackson, Jeffrey J.; Lovy, Alenka; Farias, Paula; Huerta, Hernan; Molgo, Jordi; Cardenas, Cesar; Zakarian, Armen
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SaveBackbone Cyclization Turns a Venom Peptide into a Stable and Equipotent Ligand at Both Muscle and Neuronal Nicotinic Receptors
Giribaldi, Julien; Haufe, Yves; Evans, Edward R. J.; Amar, Muriel; Durner, Anna; Schmidt, Casey; Faucherre, Adele; Maati, Hamid Moha Ou; Enjalbal, Christine; Molgo, Jordi; Servent, Denis; Wilson, David T.; Daly, Norelle L.; Nicke, Annette; Dutertre, Sebastien
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SaveCancer cells with defective oxidative phosphorylation require endoplasmic reticulum-to-mitochondria Ca2+ transfer for survival
Cardenas, Cesar; Lovy, Alenka; Silva-Pavez, Eduardo; Urra, Felix; Mizzoni, Craig; Ahumada-Castro, Ulises; Bustos, Galdo; Jana, Fabian; Cruz, Pablo; Farias, Paula; Mendoza, Elizabeth; Huerta, Hernan; Murgas, Paola; Hunter, Martin; Rios, Melany; Cerda, Oscar; Georgakoudi, Irene; Zakarian, Armen; Molgo, Jordi; Foskett, J. Kevin
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SavePinnatoxins' Deleterious Effects on Cholinergic Networks: From Experimental Models to Human Health
Delcourt, Nicolas; Lagrange, Emmeline; Abadie, Eric; Fessard, Valerie; Fremy, Jean-Marc; Vernoux, Jean-Paul; Peyrat, Marie-Benedicte; Maignien, Thomas; Arnich, Nathalie; Molgo, Jordi; Mattei, Cesar
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SaveAptamer Efficacies for In Vitro and In Vivo Modulation of αC-Conotoxin PrXA Pharmacology
Taiwe, Germain Sotoing; Montnach, Jerome; Nicolas, Sebastien; De Waard, Stephan; Fiore, Emmanuelle; Peyrin, Eric; Abd El-Aziz, Tarek Mohamed; Amar, Muriel; Molgo, Jordi; Ronjat, Michel; Servent, Denis; Ravelet, Corinne; De Waard, Michel
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SaveInositol trisphosphate receptor-mediated Ca2+ signalling stimulates mitochondrial function and gene expression in core myopathy patients
Suman, Matteo; Sharpe, Jenny A.; Bentham, Robert B.; Kotiadis, Vassilios N.; Menegollo, Michela; Pignataro, Viviana; Molgo, Jordi; Muntoni, Francesco; Duchen, Michael R.; Pegoraro, Elena; Szabadkai, Gyorgy
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