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Expanding the human proteome with microproteins and peptideins Deutsch, Eric W.; Kok, Leron W.; Mudge, Jonathan M.; Valls, Cristian F.; Jungreis, Irwin; Ruiz-Orera, Jorge; Sun, Zhi; Kusebauch, Ulrike; Fierro-Monti, Ivo; Abelin, Jennifer G.; Alba, M. Mar; Aspden, Julie L.; Bandyopadhyay, Sreejan; Banerjee, Kaushik; Baranov, Pavel V.; Bazzini, Ariel A.; Bourassa, Francis; Bruford, Elspeth A.; Calviello, Lorenzo; Carr, Steven A.; Carvunis, Anne-Ruxandra; Chothani, Sonia; Clauwaert, Jim; Dean, Kellie; Faridi, Pouya; Frankish, Adam; Goodale, Amy; Green, Thomas; Hubner, Norbert; Ingolia, Nicholas T.; Kellis, Manolis; Magrane, Michele; Martin, Maria Jesus; Martinez, Thomas F.; Menschaert, Gerben; Ohler, Uwe; Orchard, Sandra; Potter, Alisa; Rackham, Owen J. L.; Rees, Matthew G.; Root, David E.; Roth, Jennifer A.; Roucou, Xavier; Sialana, Fernando J.; Slavoff, Sarah A.; Swirski, Michal I.; Tierney, Jack A. S.; Trifiro, Felix-Antoine; Valen, Eivind; Vasylieva, Valeriia; Wacholder, Aaron; Wang, Shengbo; Wang, Li; Weissman, Jonathan S.; Wu, Wei; Choudhary, Jyoti S.; Bassani-Sternberg, Michal; Vizcaino, Juan Antonio; Ternette, Nicola; Brunet, Marie A.; Moritz, Robert L.; Prensner, John R.; van Heesch, Sebastiaan Share Save
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Tegavivint triggers TECR-dependent nonapoptotic cancer cell death Leak, Logan; Wang, Ziwei; Joseph, Alby J.; Johnson, Brianna; Chan, Alyssa A.; Decosto, Cassandra M.; Magtanong, Leslie; Ko, Pin-Joe; Lee, Weaverly Colleen; Ritho, Joan; Manukian, Sophia; Millner, Alec; Chitkara, Shweta; Salinas, Jennifer J.; Skouta, Rachid; Rees, Matthew G.; Ronan, Melissa M.; Roth, Jennifer A.; Myers, Chad L.; Moffat, Jason; Boone, Charles; Bensinger, Steven J.; Nathanson, David A.; Atilla-Gokcumen, G. Ekin; Moding, Everett J. Share Save
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Article Targeted degradation of CDK9 potently disrupts the network Toure, Mohammed A.; Motoyama, Keisuke; Xiang, Yichen; Urgiles, Julie; Kabinger, Florian; Koglin, Ann-Sophie; Iyer, Ramya S.; Gagnon, Kaitlyn; Kumar, Amruth; Ojeda, Samuel; Harrison, Drew A.; Rees, Matthew G.; Roth, Jennifer A.; Ott, Christopher J.; Schiavoni, Richard; Whittaker, Charles A.; Levine, Stuart S.; White, Forest M.; Calo, Eliezer; Richters, Andre; Koehler, Angela N. Share Save
KRASmulti inhibitor BI 3706674 shows efficacy in KRAS-driven preclinical models of cancer that supports clinical testing in patients with tumors harboring KRASG12V mutations and KRAS wild-type amplifications Tedeschi, A.; Peng, D. H.; Schischlik-Siegl, F.; Schaaf, O.; Gerlach, D.; Rocchetti, F.; Popow, J.; Broeker, J.; Wunberg, T.; Boghossian, A. S.; Rees, M. G.; Ronan, M. M.; Roth, J. A.; Williams, M.; Vellano, C.; Marszalek, J. R.; Heffernan, T. P.; Pearson, M.; Kraut, N.; Dorothea, R. Share Save
Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers Huseman, Eric D.; Lo, Anna; Fedorova, Olga; Elia, James L.; Gueble, Susan E.; Lin, Kingson; Sundaram, Ranjini K.; Oh, Joonseok; Liu, Jinchan; Menges, Fabian; Rees, Matthew G.; Ronan, Melissa M.; Roth, Jennifer A.; Batista, Victor S.; Crawford, Jason M.; Pyle, Anna M.; Bindra, Ranjit S.; Herzon, Seth B. Share Save
Genetic dependencies associated with transcription factor activities in human cancer cell lines Thatikonda, Venu; Supper, Verena; Wachter, Johannes; Kaya, Onur; Kombara, Anju; Bilgilier, Ceren; Ravichandran, Madhwesh C.; Lipp, Jesse J.; Sharma, Rahul; Badertscher, Lukas; Boghossian, Andrew S.; Rees, Matthew G.; Ronan, Melissa M.; Roth, Jennifer A.; Grosche, Sarah; Ller, Ralph A. Neumu euro; Mauri, Barbara Mair Federico; Popa, Alexandra Share Save
Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition Shendy, Noha A. M.; Bikowitz, Melissa; Sigua, Logan H.; Zhang, Yang; Mercier, Audrey; Khashana, Yousef; Nance, Stephanie; Liu, Qi; Delahunty, Ian M.; Robinson, Sarah; Goel, Vanshita; Rees, Matthew G.; Ronan, Melissa A.; Wang, Tingjian; Kocak, Mustafa; Roth, Jennifer A.; Wang, Yingzhe; Freeman, Burgess B.; Orr, Brent A.; Abraham, Brian J.; Roussel, Martine F.; Schonbrunn, Ernst; Qi, Jun; Durbin, Adam D. Share Save
KRASmulti inhibitor BI 3706674 shows efficacy in KRAS-driven preclinical models of cancer that supports clinical testing in patients with tumors harbouring KRASG12V mutations and KRAS wild-type amplifications Tedeschi, Antonio; Peng, David H.; Schischlik, Fiorella; Herdeis, Lorenz; Schaaf, Otmar; Santoro, Valeria; Gerlach, Daniel; Savarese, Fabio; Lipp, Jesse; Haslinger, Christian; Rocchetti, Francesca; Popow, Johannes; Huber, Heinrich J.; Wilding, Birgit; Treu, Matthias; Fuchs, Julian; Broeker, Joachim; Wunber, Tobias; Gmachl, Michael; Rumpel, Klaus; Rees, Matthew; Ron, Melissa; Roth, Jennifer; Williams, Mariah; Deckard, Charles; Ramamoorthy, Vandhana; Daniele, Joseph R.; Ajani, Jaffer A.; Meric-Bernstam, Funda; Kopetz, Scott; Kim, Michael; Gibbons, Don L.; Vellano, Christopher P.; Marszalek, Joseph R.; Heffernan, Timothy P.; McConnell, Darryl; Pearson, Mark; Kraut, Norbert; Rudolph, Dorothea Share Save
Novel WRN helicase inhibitors selectively target microsatellite unstable cancer cells Picco, Gabriele; Rao, Yanhua; Al Saedi, Angham; Vieira, Sara F.; Lee, Yang; Shenje, Ray; Bhosle, Shriram; Walker, Samantha; May, Kieron; Herranz-Ors, Carmen; Dicer, Cansu; Gibson, Freddy; Banerjee, Ruby; Werner, Thilo; Cottom, Josh; Peng, Yang; Deng, Nanhua; Landis, Phil; Angel, Thomas; Bush, Jacob; Rees, Matthew G.; Ronan, Melissa M.; Roth, Jennifer A.; Lightfoot, Howard; Zappacosta, Francesca; Pettinger, Jonathan; Barthorpe, Syd; Eberl, Chris; Jones, Brian; Schneck, Jess; Murphy, Dennis; Taygerly, Josh; DeMartino, Mike; Coelho, Matthew; Houseley, Jon; Schwartz, Benjamin; Garnett, Mathew J. Share Save
Assessing cancer drug combination efficacy across 900+PRISM cell lines in a multiplexed screening assay George, Ashish Bino; Nair, Shiker; Kocak, Mustafa; Nguyen, Ellen; Kalathungal, Alvin; Fazio, Anthony; Ponsi, Cole; Golabi, Aydin; Ronan, Melissa A.; Rees, Matthew G.; Roth, Jennifer A. Share Save
Optimizing 500 pooled PRISM cell lines for a 10-day assay to elucidate viability effects and mechanism of action for slower-acting therapeutics Ronan, Melissa; Ip, Blanche C.; Nguyen, Ellen; Widocki, Ursula; Sangpo, Tenzin; Kalathungal, Alvin; Diaz-Gallegos, Nashielli; Fazio, Anthony; Golabi, Aydin; Naim, Maha; George, Ashish Bino; Liu, YuhJong; Kocak, Mustafa; Puram, Rishi; Rees, Matthew G.; Roth, Jennifer Share Save
Creating a living public oncology drug resource using PRISM cell line viability screening Rees, Matthew G.; Kocak, Mustafa; Mapa, Claudine; Frederick, Dennie; Nguyen, Ellen; Kalathungal, Alvin; Fazio, Anthony; Davis, John F.; Reeves, Emily; Tucci, Ariah; Barry, Rachael; Harrington, Colleen; Eskra, Jillian; Ronan, Melissa M.; Sellers, William R.; Roth, Jennifer A. Share Save
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