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Papaverine Targets STAT Signaling: A Dual-Action Therapy Option Against SARS-CoV-2 Reus, Philipp; Torbica, Emma; Rothenburger, Tamara; Bechtel, Marco; Kandler, Joshua; Ciesek, Sandra; Gribbon, Philip; Kannt, Aimo; Cinatl, Jindrich; Bojkova, Denisa Share Save
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Proteomic, metabolomic and lipidomic profiles in community acquired pneumonia for differentiating viral and bacterial infections Rischke, Samuel; Gurke, Robert; Zielbauer, Ann-Sophie; Ziegler, Nicole; Hahnefeld, Lisa; Koehm, Michaela; Kannt, Aimo; Vehreschild, Maria J. G. T.; Geisslinger, Gerd; Rohde, Gernot; Bellinghausen, Carla; Behrens, Frank; CAPNETZ Study group, C. A. P. N. E. T. Z. Share Save
Chemogenomic Screening in a Patient-Derived 3D Fatty Liver Disease Model Reveals the CHRM1-TRPM8 Axis as a Novel Module for Targeted Intervention Youhanna, Sonia; Kemas, Aurino M.; Wright, Shane C.; Zhong, Yi; Klumpp, Britta; Klein, Kathrin; Motso, Aikaterini; Michel, Maurice; Ziegler, Nicole; Shang, Mingmei; Sabatier, Pierre; Kannt, Aimo; Sheng, Hongda; Oliva-Vilarnau, Nuria; Buettner, Florian A.; Seashore-Ludlow, Brinton; Schreiner, Jonas; Windbergs, Maike; Cornillet, Martin; Bjorkstrom, Niklas K.; Hulsmeier, Andreas J.; Hornemann, Thorsten; Olsen, Jesper V.; Wang, Yi; Gramignoli, Roberto; Sundstrom, Michael; Lauschke, Volker M. Share Save
Identification of CRTH2 as a New PPARγ-Target Gene in T Cells Suggested CRTH2 Dependent Conversion of Th2 Cells as Therapeutic Concept in COVID-19 Infection Becker, Antonia; Roehrich, Karoline; Leske, Amanda; Heinicke, Ulrike; Knape, Tilo; Kannt, Aimo; Truemper, Verena; Sohn, Kai; Wilken-Schmitz, Annett; Neb, Holger; Adam, Elisabeth H.; Laux, Volker; Parnham, Michael J.; Onasch, Valerie; Weigert, Andreas; Zacharowski, Kai; von Knethen, Andreas Share Save
Neutralizing IL-38 activates γδ T cell-dependent antitumor immunity and sensitizes for chemotherapy da Silva, Priscila; Mora, Javier; You, Xin; Wiechmann, Svenja; Putyrski, Mateusz; Garcia-Pardo, Javier; Kannt, Aimo; Ernst, Andreas; Bruene, Bernhard; Weigert, Andreas Share Save
An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD) Vacca, Michele; Kamzolas, Ioannis; Harder, Lea Morch; Oakley, Fiona; Trautwein, Christian; Hatting, Maximilian; Ross, Trenton; Bernardo, Barbara; Oldenburger, Anouk; Hjuler, Sara Toftegaard; Ksiazek, Iwona; Linden, Daniel; Schuppan, Detlef; Rodriguez-Cuenca, Sergio; Tonini, Maria Manuela; Castaneda, Tamara R.; Kannt, Aimo; Rodrigues, Cecilia M. P.; Cockell, Simon; Govaere, Olivier; Daly, Ann K.; Allison, Michael; de Lichtenberg, Kristian Honnens; Kim, Yong Ook; Lindblom, Anna; Oldham, Stephanie; Andreasson, Anne-Christine; Schlerman, Franklin; Marioneaux, Jonathon; Sanyal, Arun; Afonso, Marta B.; Younes, Ramy; Amano, Yuichiro; Friedman, Scott L.; Wang, Shuang; Bhattacharya, Dipankar; Simon, Eric; Paradis, Valerie; Burt, Alastair; Grypari, Ioanna Maria; Davies, Susan; Driessen, Ann; Yashiro, Hiroaki; Pors, Susanne; Andersen, Maja Worm; Feigh, Michael; Yunis, Carla; Bedossa, Pierre; Stewart, Michelle; Cater, Heather L.; Wells, Sara; Schattenberg, Joern M.; Anstee, Quentin M.; Tiniakos, Dina; Perfield, James W.; Petsalaki, Evangelia; Davidsen, Peter; Vidal-Puig, Antonio; Anstee, Quentin M.; Daly, Ann K.; Cockell, Simon; Tiniakos, Dina; Bedossa, Pierre; Burt, Alastair; Oakley, Fiona; Cordell, Heather J.; Day, Christopher P.; Wonders, Kristy; Missier, Paolo; McTeer, Matthew; Vale, Luke; Oluboyede, Yemi; Breckons, Matt; Boyle, Jo; Bossuyt, Patrick M.; Zafarmand, Hadi; Vali, Yasaman; Lee, Jenny; Nieuwdorp, Max; Holleboom, Adriaan G.; Angelakis, Athanasios; Verheij, Joanne; Ratziu, Vlad; Clement, Karine; Patino-Navarrete, Rafael; Pais, Raluca; Paradis, Valerie; Schuppan, Detlef; Schattenberg, Joern M.; Surabattula, Rambabu; Myneni, Sudha; Kim, Yong Ook; Straub, Beate K.; Vidal-Puig, Antonio; Vacca, Michele; Rodrigues-Cuenca, Sergio; Allison, Mike; Kamzolas, Ioannis; Petsalaki, Evangelia; Campbell, Mark; Lelliott, Chris J.; Davies, Susan; Oresic, Matej; Hyotylainen, Tuulia; McGlinchey, Aidan; Mato, Jose M.; Millet, Oscar; Dufour, Jean-Francois; Berzigotti, Annalisa; Masoodi, Mojgan; Lange, Naomi F.; Pavlides, Michael; Harrison, Stephen; Neubauer, Stefan; Cobbold, Jeremy; Mozes, Ferenc; Akhtar, Salma; Olodo-Atitebi, Seliat; Banerjee, Rajarshi; Shumbayawonda, Elizabeth; Dennis, Andrea; Andersson, Anneli; Wigley, Ioan; Romero-Gomez, Manuel; Gomez-Gonzalez, Emilio; Ampuero, Javier; Castell, Javier; Gallego-Duran, Rocio; Fernandez-Lizaranzu, Isabel; Montero-Vallejo, Rocio; Karsdal, Morten; Rasmussen, Daniel Guldager Kring; Leeming, Diana Julie; Sinisi, Antonia; Musa, Kishwar; Sandt, Estelle; Tonini, Maria Manuela; Bugianesi, Elisabetta; Rosso, Chiara; Armandi, Angelo; Marra, Fabio; Gastaldelli, Amalia; Svegliati, Gianluca; Boursier, Jerome; Francque, Sven; Vonghia, Luisa; Verrijken, An; Dirinck, Eveline; Driessen, Ann; Ekstedt, Mattias; Kechagias, Stergios; Yki-Jarvinen, Hannele; Porthan, Kimmo; Arola, Johanna; van Mil, Saskia; Papatheodoridis, George; Cortez-Pinto, Helena; Silva, Ana Paula; Rodrigues, Cecilia M. P.; Valenti, Luca; Pelusi, Serena; Petta, Salvatore; Pennisi, Grazia; Miele, Luca; Liguori, Antonio; Geier, Andreas; Rau, Monika; Trautwein, Christian; Reissing, Johanna; Aithal, Guruprasad P.; Francis, Susan; Palaniyappan, Naaventhan; Bradley, Christopher; Hockings, Paul; Schneider, Moritz; Newsome, Philip N.; Hubscher, Stefan; Wenn, David; Magnanensi, Jeremy; Trylesinski, Aldo; Mayo, Rebeca; Alonso, Cristina; Duffin, Kevin; Perfield, James W.; Chen, Yu; Hartman, Mark L.; Yunis, Carla; Miller, Melissa; Chen, Yan; McLeod, Euan James; Ross, Trenton; Bernardo, Barbara; Schoelch, Corinna; Ertle, Judith; Younes, Ramy; Coxson, Harvey; Simon, Eric; Gogain, Joseph; Ostroff, Rachel; Alexander, Leigh; Biegel, Hannah; Kjaer, Mette Skalshoi; Harder, Lea Morch; Al-Sari, Naba; Veidal, Sanne Skovgard; Oldenburger, Anouk; Ellegaard, Jens; Balp, Maria-Magdalena; Jennings, Lori; Martic, Miljen; Loffler, Jurgen; Applegate, Douglas; Torstenson, Richard; Linden, Daniel; Fournier-Poizat, Celine; Llorca, Anne; Kalutkiewicz, Michael; Pepin, Kay; Ehman, Richard; Horan, Gerald; Ho, Gideon; Tai, Dean; Chng, Elaine; Xiao, Teng; Patterson, Scott D.; Billin, Andrew; Doward, Lynda; Twiss, James; Thakker, Paresh; Derdak, Zoltan; Yashiro, Hiroaki; Landgren, Henrik; Lackner, Carolin; Gouw, Annette; Hytiroglou, Prodromos; Govaere, Olivier; Brass, Clifford Share Save
Short-term predictor for COVID-19 severity from a longitudinal multi-omics study for practical application in intensive care units Kugler, Sabine; Hahnefeld, Lisa; Kloka, Jan Andreas; Ginzel, Sebastian; Nuerenberg-Goloub, Elina; Zinn, Sebastian; Vehreschild, Maria J. G. T.; Zacharowski, Kai; Lindau, Simone; Ullrich, Evelyn; Burmeister, Jan; Kohlhammeri, Joern; Schwaeble, Joachim; Gurke, Robert; Dorochow, Erika; Bennett, Alexandre; Dauth, Stephanie; Campe, Julia; Knape, Tilo; Lauxd, Volker; Kannta, Aimo; Koehm, Michaela; Geisslinger, Gerd; Resch, Eduard; Behrens, Frank Share Save
Drug repurposing for the treatment of COVID-19: Targeting nafamostat to the lungs by a liposomal delivery system Reus, Philipp; Guthmann, Hadar; Uhlig, Nadja; Agbaria, Majd; Issmail, Leila; Eberlein, Valentina; Nordling-David, Mirjam M.; Jbara-Agbaria, Doaa; Ciesek, Sandra; Bojkova, Denisa; Cinatl, Jindrich; Burger-Kentischer, Anke; Rupp, Steffen; Zaliani, Andrea; Grunwald, Thomas; Gribbon, Philip; Kannt, Aimo; Golomb, Gershon Share Save
Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders Ruf, Sven; Rajagopal, Sridharan; Kadnur, Sanjay Venkatachalapathi; Hallur, Mahanandeesha S.; Rani, Shilpa; Kristam, Rajendra; Swaminathan, Srinivasan; Zope, Bharat Ravindra; Gondrala, Pavan Kumar; Swamy, Indu; Putta, V. P. Rama Kishore; Kandan, Saravanan; Zech, Gernot; Schreuder, Herman; Rudolph, Christine; Elvert, Ralf; Czech, Joerg; Birudukota, Swarnakumari; Siddiqui, M. Amir; Anand, Niranjan Naranapura; Mane, Vishal Subhash; Dittakavi, Sreekanth; Suresh, Juluri; Gosu, Ramachandraiah; Ramesh, Mullangi; Yura, Takeshi; Dhakshinamoorthy, Saravanakumar; Kannt, Aimo Share Save
Analysis of 16 studies in nine rodent models does not support the hypothesis that diabetic polyuria is a main reason of urinary bladder enlargement Yesilyurt, Zeynep E.; Matthes, Jan; Hintermann, Edith; Castaneda, Tamara R.; Elvert, Ralf; Beltran-Ornelas, Jesus H.; Silva-Velasco, Diana L.; Xia, Ning; Kannt, Aimo; Christen, Urs; Centurion, David; Li, Huige; Pautz, Andrea; Arioglu-Inan, Ebru; Michel, Martin C. Share Save
The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS route for SARS-CoV-2 Krasemann, Susanne; Haferkamp, Undine; Pfefferle, Susanne; Woo, Marcel S.; Heinrich, Fabian; Schweizer, Michaela; Appelt-Menzel, Antje; Cubukova, Alevtina; Barenberg, Janica; Leu, Jennifer; Hartmann, Kristin; Thies, Edda; Littau, Jessica Lisa; Sepulveda-Falla, Diego; Zhang, Liang; Ton, Kathy; Liang, Yan; Matschke, Jakob; Ricklefs, Franz; Sauvigny, Thomas; Sperhake, Jan; Fitzek, Antonia; Gerhartl, Anna; Brachner, Andreas; Geiger, Nina; Koenig, Eva-Maria; Bodem, Jochen; Franzenburg, Soren; Franke, Andre; Moese, Stefan; Mueller, Franz-Josef; Geisslinger, Gerd; Claussen, Carsten; Kannt, Aimo; Zaliani, Andrea; Gribbon, Philip; Ondruschka, Benjamin; Neuhaus, Winfried; Friese, Manuel A.; Glatzel, Markus; Pless, Ole Share Save
Mastiha has efficacy in immune-mediated inflammatory diseases through a microRNA-155 Th17 dependent action Amerikanou, Charalampia; Papada, Efstathia; Gioxari, Aristea; Smyrnioudis, Ilias; Kleftaki, Stamatia-Angeliki; Valsamidou, Evdokia; Bruns, Victoria; Banerjee, Rajarshi; Trivella, Maria Giovanna; Milic, Natasa; Medic-Stojanoska, Milica; Gastaldelli, Amalia; Kannt, Aimo; Dedoussis, George, V; Kaliora, Andriana C. Share Save
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