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G

Guido Silvestri

emory university

81H-index
418Paper Count
2.7WCitation Count
Published Papers 221
Publication Date
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Vaccination elicits HIV broadly neutralizing antibodies in primates
errNature
IF48.5
err2026-06-30
err0
PREAI
errJon M. Steichen; Patrick J. Madden; Claudia T. Flynn; Swastik Phulera; Monolina Shil; Oleksandr Kalyuzhniy; Alessia Liguori; Carolyne Kifude; Leigh M. Sewall; Christopher A. Cottrell; Krystal M. Ma; Sabyasachi Baboo; Jolene K. Diedrich; Katherine McKenney; Allan C. deCamp; Diane G. Carnathan; Ivy Phung; Parham Ramezani-Rad; Ester Marina-Zárate; Brian Freeman; Zhenfei Xie; Jeong Hyun Lee; Troy Sincomb; Nicole Phelps; Danny Lu; Diana Goodwin; Ryan Tingle; Yumiko Adachi; Nushin Alavi; Jenny Tran; Andy S. Tran; Alyne Nascimento; Catherine Sovie; Daniel L. V. Bader; Hannah Voic; Xiaoya Zhou; Grace Pixton; Agnes Walsh; Mariane B. Melo; Torben Schiffner; Facundo D. Batista; Dennis R. Burton; Darrell J. Irvine; James C. Paulson; John R. Yates; Gabriel Ozorowski; Andrew B. Ward; Guido Silvestri; Shane Crotty; William R. Schief
errShare
errSave
Highly functional and prolonged germinal center T follicular helper cell responses are associated with enhanced neutralizing antibody development
errImmunity
IF26.3
err2025-11-07
err0
PREAI
errEster Marina-Zárate; Henry J. Sutton; Paul G. Lopez; Tasha K. Altheide; Michael Bick; Iszac Burton; Elana Ben-Akiva; Katarzyna Kaczmarek Michaels; Kesha Hyacinth; Brandon S. Healy; Deuk Lim; Lars Hangartner; Dennis R. Burton; Diane G. Carnathan; Guido Silvestri; William R. Schief; Darrell J. Irvine; Shane Crotty
errShare
errSave
Identifying correlates of viral rebound timing and viral control in SHIV-infected infant macaques after ART interruption
errScience Translational Medicine
IF14.6
err2025-10-29
err0
PREAI
errVeronica Obregon-Perko; Achal Awasthi; Richard Barfield; Stella J. Berendam; Bhrugu Yagnik; Tiffany Styles; Greg Tharp; Prachi M. Gupta; Gloria Mensah; Margaret Neja; Mithra Kumar; Emily Fray; Fan Bu; Justin Pollara; Marina Tuyishime; Guido Ferrari; Janet D. Siliciano; Robert F. Siliciano; Maud Mavigner; Guido Silvestri; Rama R. Amara; Steve Bosinger; Genevieve G. Fouda; Sallie R. Permar; Cliburn Chan; Ann Chahroudi
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errSave
HIV broadly neutralizing antibody precursors to the Apex epitope induced in nonhuman primates
errScience Immunology
IF16.3
err2025-08-22
err0
PREAI
errKrystal M. Ma; Henry J. Sutton; Payal P. Pratap; Jon M. Steichen; Diane Carnathan; James Quinn; Oleksandr Kalyuzhniy; Alessia Liguori; Sashank Agrawal; Sabyasachi Baboo; Patrick Madden; Christopher A. Cottrell; Jordan R. Willis; Jeong-Hyun Lee; Elise Landais; Xiaozhen Hu; Parham Ramezani-Rad; Gabriel Ozorowski; Vanessa R. Lewis; Jolene K. Diedrich; Xiaoya Zhou; Tasha K. Altheide; Nicole Phelps; Erik Georgeson; Nushin B. Alavi; Danny Lu; Saman Eskandarzadeh; Michael Kubitz; Yumiko Adachi; Tina-Marie Mullen; Murillo Silva; Mariane B. Melo; Sunny Himansu; Darrell J. Irvine; Dennis R. Burton; John R. Yates; James C. Paulson; Devin Sok; Ian A. Wilson; Guido Silvestri; Andrew B. Ward; Shane Crotty; William R. Schief
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errSave
Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques
errnpj Vaccines
IF6.5
err2025-08-20
err0
errOAAI
errPayal P. Pratap; Christopher A. Cottrell; James Quinn; Diane G. Carnathan; Daniel L. V. Bader; Andy S. Tran; Chiamaka A. Enemuo; Julia T. Ngo; Sara T. Richey; Hongmei Gao; Xiaoying Shen; Kelli M. Greene; Jonathan Hurtado; Katarzyna Kaczmarek Michaels; Elana Ben-Akiva; Ashley Lemnios; Mariane B. Melo; Joel D. Allen; Gabriel Ozorowski; Max Crispin; Bryan Briney; David Montefiori; Guido Silvestri; Darrell J. Irvine; Shane Crotty; Andrew B. Ward
errShare
errSave
Vaccination with an mRNA-encoded membrane-bound HIV envelope trimer induces neutralizing antibodies in animal models
errScience Translational Medicine
IF14.6
err2025-07-30
err0
errOAAI
errParham Ramezani-Rad; Christopher A. Cottrell; Ester Marina-Zárate; Alessia Liguori; Elise Landais; Jonathan L. Torres; Amber Myers; Jeong Hyun Lee; Sabyasachi Baboo; Claudia Flynn; Katherine McKenney; Eugenia Salcedo; Xiaoya Zhou; Oleksandr Kalyuzhniy; Erik Georgeson; Nicole Phelps; Danny Lu; Saman Eskandarzadeh; Sergey Menis; Michael Kubitz; Bettina Groschel; Nushin Alavi; Abigail M. Jackson; Wen-Hsin Lee; Andy S. Tran; Elana Ben-Akiva; Katarzyna Kaczmarek Michaels; Jolene K. Diedrich; Chiamaka A. Enemuo; Vanessa Lewis; Arpan Pradhan; Sudhir Pai Kasturi; Torben Schiffner; Jon M. Steichen; Diane G. Carnathan; Sunny Himansu; John R. Yates; James C. Paulson; Gabriel Ozorowski; Darrell J. Irvine; Guido Silvestri; Devin Sok; Andrew B. Ward; Shane Crotty; William R. Schief
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errSave
Convergence and divergence of B cell responses in two HIV-1 Env immunizations in Rhesus macaques
errCOMMUNICATIONS MEDICINE
IF6.3
err2025-05-15
err0
errOAAI
errDeLuca, Jenna M.; Blasi, Maria; McGee, Taylor J.; Jha, Shalini; Shen, Xiaoying; Gu, Shuqin; Pollara, Justin; Kerkau, Melissa; Purwar, Mansi; Carnathan, Diane G.; Negri, Donatella; Cara, Andrea; Wollenberg, Kurt; Wiehe, Kevin; Saunders, Kevin O.; Lu, Shan; Silvestri, Guido; Weiner, David B.; Klotman, Mary E.; Ferrari, Guido; Anthony Moody, M.; Bonsignori, Mattia
errShare
errSave
Vaccination of nonhuman primates elicits a broadly neutralizing antibody lineage targeting a quaternary epitope on the HIV-1 Env trimer
errImmunity
IF26.3
err2025-05-07
err0
PREAI
errFabian-Alexander Schleich; Shridhar Bale; Javier Guenaga; Gabriel Ozorowski; Monika Àdori; Xiaohe Lin; Xaquin Castro Dopico; Richard Wilson; Mark Chernyshev; Alma Teresia Cotgreave; Marco Mandolesi; Jocelyn Cluff; Esmeralda D. Doyle; Leigh M. Sewall; Wen-Hsin Lee; Shiyu Zhang; Sijy O’Dell; Brandon S. Healy; Deuk Lim; Vanessa R. Lewis; Elana Ben-Akiva; Darrell J. Irvine; Nicole A. Doria-Rose; Martin Corcoran; Diane Carnathan; Guido Silvestri; Ian A. Wilson; Andrew B. Ward; Gunilla B. Karlsson Hedestam; Richard T. Wyatt
errShare
errSave
Diverse priming outcomes under conditions of very rare precursor B cells
errIMMUNITY
IF26.3
err2025-04-01
err0
errOAAI
errMadden, Patrick J.; Marina-Zarate, Ester; Rodrigues, Kristen A.; Steichen, Jon M.; Shil, Monolina; Ni, Kaiyuan; Michaels, Katarzyna Kaczmarek; Maiorino, Laura; Upadhyay, Amit A.; Saha, Swati; Pradhan, Arpan; Kalyuzhiny, Oleksandr; Liguori, Alessia; Lopez, Paul G.; Phung, Ivy; Flynn, Claudia; Zhou, Amelia; Melo, Mariane B.; Lemnios, Ashley; Phelps, Nicole; Georgeson, Erik; Alavi, Nushin; Kubitz, Michael; Lu, Danny; Eskandarzadeh, Saman; Metz, Amanda; Rodriguez, Oscar L.; Shields, Kaitlyn; Schultze, Steven; Smith, Melissa L.; Healy, Brandon S.; Lim, Deuk; Lewis, Vanessa R.; Ben-Akiva, Elana; Pinney III, William; Gregory, Justin; Xiao, Shuhao; Carnathan, Diane G.; Kasturi, Sudhir Pai; Watson, Corey T.; Bosinger, Steven E.; Silvestri, Guido; Schief, William R.; Irvine, Darrell J.; Crotty, Shane
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errSave
Safety, pharmacokinetics, and biological activity of CD4-mimetic BNM-III-170 in SHIV-infected rhesus macaques
errJOURNAL OF VIROLOGY
IF3.8
err2025-04-01
err0
errOAAI
errViox, Elise G.; Richard, Jonathan; Grandea, Andres G., III; Nguyen, Kevin; Harper, Justin; Auger, James; Ding, Shilei; Gasser, Romain; Prevost, Jeremie; Marchitto, Lorie; Medjahed, Halima; Bourassa, Catherine; Gaudette, Fleur; Pagliuzza, Amelie; Trifone, Cesar Ariel; Gavegnano, Christina; Hurwitz, Selwyn J.; Park, Jun; Clark, Natasha M.; Hammad, Iman; Capuano III, Saverio; Martin, Malcolm A.; Schinazi, Raymond F.; Silvestri, Guido; Kulpa, Deanna A.; Kumar, Priti; Chomont, Nicolas; Pazgier, Marzena; Smith III, Amos B.; Sodroski, Joseph; Evans, David T.; Finzi, Andres; Paiardini, Mirko
errShare
errSave
Immune-mediated strategies to solving the HIV reservoir problem
errNATURE REVIEWS IMMUNOLOGY
IF60.9
err2025-02-13
err1
PREAI
errKulpa, Deanna A.; Paiardini, Mirko; Silvestri, Guido
errShare
errSave
Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption (vol 25, pg 1900, 2024)
errNATURE IMMUNOLOGY
IF27.6
err2025-01-16
err0
errOAAI
errPereira Ribeiro, Susan; Strongin, Zachary; Soudeyns, Hugo; ten-Caten, Felipe; Ghneim, Khader; Pacheco Sanchez, Gabriela; Xavier de Medeiros, Giuliana; Del Rio Estrada, Perla Mariana; Pelletier, Adam-Nicolas; Hoang, Timothy; Nguyen, Kevin; Harper, Justin; Jean, Sherrie; Wallace, Chelsea; Balderas, Robert; Lifson, Jeffrey D.; Raghunathan, Gopalan; Rimmer, Eric; Pastuskovas, Cinthia V.; Wu, Guoxin; Micci, Luca; Ribeiro, Ruy M.; Chan, Chi Ngai; Estes, Jacob D.; Silvestri, Guido; Gorman, Daniel M.; Howell, Bonnie J.; Hazuda, Daria J.; Paiardini, Mirko; Sekaly, Rafick P.
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errSave
A novel HIV triple broadly neutralizing antibody (bNAb) combination-based passive immunization of infant rhesus macaques achieves durable protective plasma neutralization levels and mediates anti-viral effector functions
errPLOS ONE
IF2.6
err2024-11-11
err1
errOAAI
errDankwa, Sedem; Kosman, Christina; Dennis, Maria; Giorgi, Elena E.; Vuong, Kenneth; Pahountis, Ioanna; Garza, Ashley; Binuya, Christian; McCarthy, Janice; Mayer, Bryan T.; Ngo, Julia T.; Enemuo, Chiamaka A.; Carnathan, Diane G.; Stanfield-Oakley, Sherry; Berendam, Stella J.; Weinbaum, Carolyn; Engelman, Kathleen; Magnani, Diogo M.; Chan, Cliburn; Ferrari, Guido; Silvestri, Guido; Amara, Rama R.; Chahroudi, Ann; Permar, Sallie R.; Fouda, Genevieve G.; Goswami, Ria
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errSave
SIV infection in sooty mangabeys does not impact survival but changes the relative frequency of the main cause of death
errMBIO
IF4.7
err2024-10-16
err0
errOAAI
errCeriani, Cristina; Beisner, Brianne; Crane, Maria; Cohen, Joyce; Moore, Ian N.; Kulpa, Deanna A.; Hahn, Beatrice H.; Silvestri, Guido
errShare
errSave
Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption
errNATURE IMMUNOLOGY
IF27.6
err2024-09-12
err2
errOAAI
errPereira Ribeiro, Susan; Strongin, Zachary; Soudeyns, Hugo; ten-Caten, Felipe; Ghneim, Khader; Pacheco Sanchez, Gabriela; Xavier de Medeiros, Giuliana; Del Rio Estrada, Perla Mariana; Pelletier, Adam-Nicolas; Hoang, Timothy; Nguyen, Kevin; Harper, Justin; Jean, Sherrie; Wallace, Chelsea; Balderas, Robert; Lifson, Jeffrey D.; Raghunathan, Gopalan; Rimmer, Eric; Pastuskova, Cinthia; Wu, Guoxin; Micci, Luca; Ribeiro, Ruy M.; Chan, Chi Ngai; Estes, Jacob D.; Silvestri, Guido; Gorman, Daniel M.; Howell, Bonnie J.; Hazuda, Daria J.; Paiardini, Mirko; Sekaly, Rafick P.
errShare
errSave
Assessing the impact of autologous virus neutralizing antibodies on viral rebound time in postnatally SHIV-infected ART-treated infant rhesus macaques
errEPIDEMICS
IF2.4
err2024-09-01
err0
errOAAI
errMainou, Ellie; Berendam, Stella J.; Obregon-Perko, Veronica; Uffman, Emilie A.; Phan, Caroline T.; Shaw, George M.; Bar, Katharine J.; Kumar, Mithra R.; Fray, Emily J.; Siliciano, Janet M.; Siliciano, Robert F.; Silvestri, Guido; Permar, Sallie R.; Fouda, Genevieve G.; McCarthy, Janice; Chahroudi, Ann; Conway, Jessica M.; Chan, Cliburn
errShare
errSave
Priming antibody responses to the fusion peptide in rhesus macaques
errNPJ VACCINES
IF6.5
err2024-07-12
err0
errOAAI
errCottrell, Christopher A.; Pratap, Payal P.; Cirelli, Kimberly M.; Carnathan, Diane G.; Enemuo, Chiamaka A.; Antanasijevic, Aleksandar; Ozorowski, Gabriel; Sewall, Leigh M.; Gao, Hongmei; Allen, Joel D.; Nogal, Bartek; Silva, Murillo; Bhiman, Jinal; Pauthner, Matthias; Irvine, Darrell J.; Montefiori, David; Crispin, Max; Burton, Dennis R.; Silvestri, Guido; Crotty, Shane; Ward, Andrew B.
errShare
errSave
Distinct SIV-specific CD8+ T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence
errNATURE IMMUNOLOGY
IF27.6
err2024-06-17
err6
PREAI
errStrongin, Zachary; Marchand, Laurence Raymond; Deleage, Claire; Pampena, M. Betina; Cardenas, Maria Andrea; Beusch, Christian Michel; Hoang, Timothy N.; Urban, Elizabeth A.; Gourves, Mael; Nguyen, Kevin; Tharp, Gregory K.; Lapp, Stacey; Rahmberg, Andrew R.; Harper, Justin; Estrada, Perla M. del Rio; Gonzalez-Navarro, Mauricio; Torres-Ruiz, Fernanda; Luna-Villalobos, Yara Andrea; Avila-Rios, Santiago; Reyes-Teran, Gustavo; Sekaly, Rafick; Silvestri, Guido; Kulpa, Deanna A.; Saez-Cirion, Asier; Brenchley, Jason M.; Bosinger, Steven E.; Gordon, David Ezra; Betts, Michael R.; Kissick, Haydn T.; Paiardini, Mirko
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errSave
Vaccination induces broadly neutralizing antibody precursors to HIV gp41 (vol 25, pg 1073, 2024)
errNATURE IMMUNOLOGY
IF27.6
err2024-06-14
err0
errOAAI
errSchiffner, Torben; Phung, Ivy; Ray, Rashmi; Irimia, Adriana; Tian, Ming; Swanson, Olivia; Lee, Jeong Hyun; Lee, Chang-Chun D.; Marina-Zarate, Ester; Cho, So Yeon; Huang, Jiachen; Ozorowski, Gabriel; Skog, Patrick D.; Serra, Andreia M.; Rantalainen, Kimmo; Allen, Joel D.; Baboo, Sabyasachi; Rodriguez, Oscar L.; Himansu, Sunny; Zhou, Jianfu; Hurtado, Jonathan; Flynn, Claudia T.; McKenney, Katherine; Havenar-Daughton, Colin; Saha, Swati; Shields, Kaitlyn; Schultze, Steven; Smith, Melissa L.; Liang, Chi-Hui; Toy, Laura; Pecetta, Simone; Lin, Ying-Cing; Willis, Jordan R.; Sesterhenn, Fabian; Kulp, Daniel W.; Hu, Xiaozhen; Cottrell, Christopher A.; Zhou, Xiaoya; Ruiz, Jennifer; Wang, Xuesong; Nair, Usha; Kirsch, Kathrin H.; Cheng, Hwei-Ling; Davis, Jillian; Kalyuzhniy, Oleksandr; Liguori, Alessia; Diedrich, Jolene K.; Ngo, Julia T.; Lewis, Vanessa; Phelps, Nicole; Tingle, Ryan D.; Spencer, Skye; Georgeson, Erik; Adachi, Yumiko; Kubitz, Michael; Eskandarzadeh, Saman; Elsliger, Marc A.; Amara, Rama R.; Landais, Elise; Briney, Bryan; Burton, Dennis R.; Carnathan, Diane G.; Silvestri, Guido; Watson, Corey T.; Yates, John R.; Paulson, James C.; Crispin, Max; Grigoryan, Gevorg; Ward, Andrew B.; Sok, Devin; Alt, Frederick W.; Wilson, Ian A.; Batista, Facundo D.; Crotty, Shane; Schief, William R.
errShare
errSave
Vaccination induces broadly neutralizing antibody precursors to HIV gp41
errNATURE IMMUNOLOGY
IF27.6
err2024-05-30
err9
errOAAI
errSchiffner, Torben; Phung, Ivy; Ray, Rashmi; Irimia, Adriana; Tian, Ming; Swanson, Olivia; Lee, Jeong Hyun; Lee, Chang-Chun D.; Marina-Zarate, Ester; Cho, So Yeon; Huang, Jiachen; Ozorowski, Gabriel; Skog, Patrick D.; Serra, Andreia M.; Rantalainen, Kimmo; Allen, Joel D.; Baboo, Sabyasachi; Rodriguez, Oscar L.; Himansu, Sunny; Zhou, Jianfu; Hurtado, Jonathan; Flynn, Claudia T.; Mckenney, Katherine; Havenar-Daughton, Colin; Saha, Swati; Shields, Kaitlyn; Schulze, Steven; Smith, Melissa L.; Liang, Chi-Hui; Toy, Laura; Pecetta, Simone; Lin, Ying-Cing; Willis, Jordan R.; Sesterhenn, Fabian; Kulp, Daniel W.; Hu, Xiaozhen; Cottrell, Christopher A.; Zhou, Xiaoya; Ruiz, Jennifer; Wang, Xuesong; Nair, Usha; Kirsch, Kathrin H.; Cheng, Hwei-Ling; Davis, Jillian; Kalyuzhniy, Oleksandr; Liguori, Alessia; Diedrich, Jolene K.; Ngo, Julia T.; Lewis, Vanessa; Phelps, Nicole; Tingle, Ryan D.; Spencer, Skye; Georgeson, Erik; Adachi, Yumiko; Kubitz, Michael; Eskandarzadeh, Saman; Elsliger, Marc A.; Amara, Rama R.; Landais, Elise; Briney, Bryan; Burton, Dennis R.; Carnathan, Diane G.; Silvestri, Guido; Watson, Corey T.; Yates III, John R.; Paulson, James C.; Crispin, Max; Grigoryan, Gevorg; Ward, Andrew B.; Sok, Devin; Alt, Frederick W.; Wilson, Ian A.; Batista, Facundo D.; Crotty, Shane; Schief, William R.
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errSave

Research Directions

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Co-authors
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