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S

Shane Crotty

The Scripps Research Institute

104H-index
375Paper Count
5.6WCitation Count
Published Papers 186
Publication Date
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Vaccination elicits HIV broadly neutralizing antibodies in primates
errNature
IF48.5
err2026-06-30
err0
PREAI
errJon M. Steichen; Patrick J. Madden; Claudia T. Flynn; Swastik Phulera; Monolina Shil; Oleksandr Kalyuzhniy; Alessia Liguori; Carolyne Kifude; Leigh M. Sewall; Christopher A. Cottrell; Krystal M. Ma; Sabyasachi Baboo; Jolene K. Diedrich; Katherine McKenney; Allan C. deCamp; Diane G. Carnathan; Ivy Phung; Parham Ramezani-Rad; Ester Marina-Zárate; Brian Freeman; Zhenfei Xie; Jeong Hyun Lee; Troy Sincomb; Nicole Phelps; Danny Lu; Diana Goodwin; Ryan Tingle; Yumiko Adachi; Nushin Alavi; Jenny Tran; Andy S. Tran; Alyne Nascimento; Catherine Sovie; Daniel L. V. Bader; Hannah Voic; Xiaoya Zhou; Grace Pixton; Agnes Walsh; Mariane B. Melo; Torben Schiffner; Facundo D. Batista; Dennis R. Burton; Darrell J. Irvine; James C. Paulson; John R. Yates; Gabriel Ozorowski; Andrew B. Ward; Guido Silvestri; Shane Crotty; William R. Schief
errShare
errSave
Rapid boosting increases germinal center responses to sequential vaccines
errNature Immunology
IF27.6
err2026-06-23
err0
PREAI
errSonya Haupt; Christopher A. Cottrell; Xiaoya Zhou; Jeong Hyun Lee; Alessia Liguori; Nushin Alavi; Danny Lu; Nicole Phelps; Diana Goodwin; Elana Ben-Akiva; Agnes A. Walsh; Darrell J. Irvine; William R. Schief; Shane Crotty
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errSave
Local B cell immunity and durable memory after live-attenuated influenza intranasal vaccination of humans
errScience Translational Medicine
IF14.6
err2026-04-29
err0
PREAI
errHannah D. Stacey; Lucas Garin-Ortega; Paul G. Lopez; Parham Ramezani-Rad; Sydney I. Ramirez; Farhoud Faraji; Disha Bhavsar; Gina Levi; Florian Krammer; Shane Crotty
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errSave
Virus glycoprotein nanodisc platform for vaccine analytics
errNature Communications
IF15.7
err2026-02-10
err0
errOAAI
errKimmo Rantalainen; Alessia Liguori; Gabriel Ozorowski; Claudia Flynn; Jon M. Steichen; Olivia M. Swanson; Patrick J. Madden; Sabyasachi Baboo; Swastik Phulera; Anant Gharpure; Danny Lu; Oleksandr Kalyuzhniy; Patrick Skog; Sierra Terada; Monolina Shil; Jolene K. Diedrich; Erik Georgeson; Ryan Tingle; Saman Eskandarzadeh; Wen-Hsin Lee; Nushin Alavi; Diana Goodwin; Michael Kubitz; Sonya Amirzehni; Sunny Himansu; Devin Sok; Jeong Hyun Lee; John R. Yates; James C. Paulson; Shane Crotty; Torben Schiffner; Andrew B. Ward; William R. Schief
errShare
errSave
Highly functional and prolonged germinal center T follicular helper cell responses are associated with enhanced neutralizing antibody development
errImmunity
IF26.3
err2025-11-07
err0
PREAI
errEster Marina-Zárate; Henry J. Sutton; Paul G. Lopez; Tasha K. Altheide; Michael Bick; Iszac Burton; Elana Ben-Akiva; Katarzyna Kaczmarek Michaels; Kesha Hyacinth; Brandon S. Healy; Deuk Lim; Lars Hangartner; Dennis R. Burton; Diane G. Carnathan; Guido Silvestri; William R. Schief; Darrell J. Irvine; Shane Crotty
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errSave
Differential BCL6-mediated transcriptional regulation of human TFH cells
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errKuen, Da Sol; Bhat, Numana; Crotty, Shane
errShare
errSave
The transcription factors ETS1 and RUNX3 differentially specify effector memory and tissue resident memory CD8 T cell formation
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errTsuda, Shanel M.; Nagaraja, Shashank; Getzler, Adam; Albao, Dominic S.; Diao, Huitian; Heeg, Maximilian; Kee, Barbara L.; Crotty, Shane; Goldrath, Ananda W.; Pipkin, Matthew
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errSave
Pediatric T cell and B cell responses to SARS-CoV-2 infection
errJCI INSIGHT
IF6.1
err2025-10-22
err0
errOAAI
errHills, L. Benjamin; Bhat, Numana; Hurst, Jillian H.; Myers, Amber; Burke, Thomas W.; Mcclain, Micah T.; Petzold, Elizabeth; Rotta, Alexandre T.; Turner, Nicholas A.; Grifoni, Alba; Weiskopf, Daniela; Dogariu, Yvonne; Fouda, Genevieve G.; Permar, Sallie R.; Sette, Alessandro; Woods, Christopher W.; Kelly, Matthew S.; Crotty, Shane
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errSave
Simultaneous induction of multiple classes of broadly neutralizing antibody precursors by combination germline-targeting immunization in nonhuman primates
errScience Immunology
IF16.3
err2025-10-17
err0
PREAI
errHenry J. Sutton; Krystal M. Ma; Jon M. Steichen; Torben Schiffner; Tasha K. Altheide; Alessia Liguori; Danny Lu; Michael Kubitz; Erik Georgeson; Nicole Phelps; Ryan Tingle; Nushin B. Alavi; Elana Ben-Akiva; Xiaoya Zhou; Carolyne Kifude; Claudia T. Flynn; Eva Rakasz; Darrell J. Irvine; William R. Schief; Shane Crotty
errShare
errSave
HIV broadly neutralizing antibody precursors to the Apex epitope induced in nonhuman primates
errScience Immunology
IF16.3
err2025-08-22
err0
PREAI
errKrystal M. Ma; Henry J. Sutton; Payal P. Pratap; Jon M. Steichen; Diane Carnathan; James Quinn; Oleksandr Kalyuzhniy; Alessia Liguori; Sashank Agrawal; Sabyasachi Baboo; Patrick Madden; Christopher A. Cottrell; Jordan R. Willis; Jeong-Hyun Lee; Elise Landais; Xiaozhen Hu; Parham Ramezani-Rad; Gabriel Ozorowski; Vanessa R. Lewis; Jolene K. Diedrich; Xiaoya Zhou; Tasha K. Altheide; Nicole Phelps; Erik Georgeson; Nushin B. Alavi; Danny Lu; Saman Eskandarzadeh; Michael Kubitz; Yumiko Adachi; Tina-Marie Mullen; Murillo Silva; Mariane B. Melo; Sunny Himansu; Darrell J. Irvine; Dennis R. Burton; John R. Yates; James C. Paulson; Devin Sok; Ian A. Wilson; Guido Silvestri; Andrew B. Ward; Shane Crotty; William R. Schief
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errSave
Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques
errnpj Vaccines
IF6.5
err2025-08-20
err0
errOAAI
errPayal P. Pratap; Christopher A. Cottrell; James Quinn; Diane G. Carnathan; Daniel L. V. Bader; Andy S. Tran; Chiamaka A. Enemuo; Julia T. Ngo; Sara T. Richey; Hongmei Gao; Xiaoying Shen; Kelli M. Greene; Jonathan Hurtado; Katarzyna Kaczmarek Michaels; Elana Ben-Akiva; Ashley Lemnios; Mariane B. Melo; Joel D. Allen; Gabriel Ozorowski; Max Crispin; Bryan Briney; David Montefiori; Guido Silvestri; Darrell J. Irvine; Shane Crotty; Andrew B. Ward
errShare
errSave
Vaccination with an mRNA-encoded membrane-bound HIV envelope trimer induces neutralizing antibodies in animal models
errScience Translational Medicine
IF14.6
err2025-07-30
err0
errOAAI
errParham Ramezani-Rad; Christopher A. Cottrell; Ester Marina-Zárate; Alessia Liguori; Elise Landais; Jonathan L. Torres; Amber Myers; Jeong Hyun Lee; Sabyasachi Baboo; Claudia Flynn; Katherine McKenney; Eugenia Salcedo; Xiaoya Zhou; Oleksandr Kalyuzhniy; Erik Georgeson; Nicole Phelps; Danny Lu; Saman Eskandarzadeh; Sergey Menis; Michael Kubitz; Bettina Groschel; Nushin Alavi; Abigail M. Jackson; Wen-Hsin Lee; Andy S. Tran; Elana Ben-Akiva; Katarzyna Kaczmarek Michaels; Jolene K. Diedrich; Chiamaka A. Enemuo; Vanessa Lewis; Arpan Pradhan; Sudhir Pai Kasturi; Torben Schiffner; Jon M. Steichen; Diane G. Carnathan; Sunny Himansu; John R. Yates; James C. Paulson; Gabriel Ozorowski; Darrell J. Irvine; Guido Silvestri; Devin Sok; Andrew B. Ward; Shane Crotty; William R. Schief
errShare
errSave
Diverse priming outcomes under conditions of very rare precursor B cells
errIMMUNITY
IF26.3
err2025-04-01
err0
errOAAI
errMadden, Patrick J.; Marina-Zarate, Ester; Rodrigues, Kristen A.; Steichen, Jon M.; Shil, Monolina; Ni, Kaiyuan; Michaels, Katarzyna Kaczmarek; Maiorino, Laura; Upadhyay, Amit A.; Saha, Swati; Pradhan, Arpan; Kalyuzhiny, Oleksandr; Liguori, Alessia; Lopez, Paul G.; Phung, Ivy; Flynn, Claudia; Zhou, Amelia; Melo, Mariane B.; Lemnios, Ashley; Phelps, Nicole; Georgeson, Erik; Alavi, Nushin; Kubitz, Michael; Lu, Danny; Eskandarzadeh, Saman; Metz, Amanda; Rodriguez, Oscar L.; Shields, Kaitlyn; Schultze, Steven; Smith, Melissa L.; Healy, Brandon S.; Lim, Deuk; Lewis, Vanessa R.; Ben-Akiva, Elana; Pinney III, William; Gregory, Justin; Xiao, Shuhao; Carnathan, Diane G.; Kasturi, Sudhir Pai; Watson, Corey T.; Bosinger, Steven E.; Silvestri, Guido; Schief, William R.; Irvine, Darrell J.; Crotty, Shane
errShare
errSave
Early antiviral CD4+and CD8+Tcells are associated with upper airway clearance of SARS-CoV-2
errJCI INSIGHT
IF6.1
err2024-12-20
err0
errOAAI
errRamirez, Sydney I.; Lopez, Paul G.; Faraji, Farhoud; Parikh, Urvi M.; Heaps, Amy; Ritz, Justin; Moser, Carlee; Eron, Joseph J.; Wohl, David; Currier, Judith; Daar, Eric S.; Greninger, Alex; Klekotka, Paul; Grifoni, Alba; Weiskopf, Daniela; Sette, Alessandro; Peters, Bjoern; Hughes, Michael D.; Chew, Kara W.; Smith, Davey M.; Crotty, Shane
errShare
errSave
SARS-CoV-2 Monoclonal Antibody Treatment Followed by Vaccination Shifts Human Memory B-Cell Epitope Recognition, Suggesting Antibody Feedback
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2024-07-22
err2
errOAAI
errBloom, Nathaniel; Ramirez, Sydney, I; Cohn, Hallie; Parikh, Urvi M.; Heaps, Amy; Sieg, Scott F.; Greninger, Alex; Ritz, Justin; Moser, Carlee; Eron, Joseph J.; Bajic, Goran; Currier, Judith S.; Klekotka, Paul; Wohl, David A.; Daar, Eric S.; Li, Jonathan; Hughes, Michael D.; Chew, Kara W.; Smith, Davey M.; Crotty, Shane; Coelho, Camila H.
errShare
errSave
Priming antibody responses to the fusion peptide in rhesus macaques
errNPJ VACCINES
IF6.5
err2024-07-12
err0
errOAAI
errCottrell, Christopher A.; Pratap, Payal P.; Cirelli, Kimberly M.; Carnathan, Diane G.; Enemuo, Chiamaka A.; Antanasijevic, Aleksandar; Ozorowski, Gabriel; Sewall, Leigh M.; Gao, Hongmei; Allen, Joel D.; Nogal, Bartek; Silva, Murillo; Bhiman, Jinal; Pauthner, Matthias; Irvine, Darrell J.; Montefiori, David; Crispin, Max; Burton, Dennis R.; Silvestri, Guido; Crotty, Shane; Ward, Andrew B.
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errSave
Vaccination induces broadly neutralizing antibody precursors to HIV gp41 (vol 25, pg 1073, 2024)
errNATURE IMMUNOLOGY
IF27.6
err2024-06-14
err0
errOAAI
errSchiffner, Torben; Phung, Ivy; Ray, Rashmi; Irimia, Adriana; Tian, Ming; Swanson, Olivia; Lee, Jeong Hyun; Lee, Chang-Chun D.; Marina-Zarate, Ester; Cho, So Yeon; Huang, Jiachen; Ozorowski, Gabriel; Skog, Patrick D.; Serra, Andreia M.; Rantalainen, Kimmo; Allen, Joel D.; Baboo, Sabyasachi; Rodriguez, Oscar L.; Himansu, Sunny; Zhou, Jianfu; Hurtado, Jonathan; Flynn, Claudia T.; McKenney, Katherine; Havenar-Daughton, Colin; Saha, Swati; Shields, Kaitlyn; Schultze, Steven; Smith, Melissa L.; Liang, Chi-Hui; Toy, Laura; Pecetta, Simone; Lin, Ying-Cing; Willis, Jordan R.; Sesterhenn, Fabian; Kulp, Daniel W.; Hu, Xiaozhen; Cottrell, Christopher A.; Zhou, Xiaoya; Ruiz, Jennifer; Wang, Xuesong; Nair, Usha; Kirsch, Kathrin H.; Cheng, Hwei-Ling; Davis, Jillian; Kalyuzhniy, Oleksandr; Liguori, Alessia; Diedrich, Jolene K.; Ngo, Julia T.; Lewis, Vanessa; Phelps, Nicole; Tingle, Ryan D.; Spencer, Skye; Georgeson, Erik; Adachi, Yumiko; Kubitz, Michael; Eskandarzadeh, Saman; Elsliger, Marc A.; Amara, Rama R.; Landais, Elise; Briney, Bryan; Burton, Dennis R.; Carnathan, Diane G.; Silvestri, Guido; Watson, Corey T.; Yates, John R.; Paulson, James C.; Crispin, Max; Grigoryan, Gevorg; Ward, Andrew B.; Sok, Devin; Alt, Frederick W.; Wilson, Ian A.; Batista, Facundo D.; Crotty, Shane; Schief, William R.
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errSave
SARS-CoV-2 breakthrough infections enhance T cell response magnitude, breadth, and epitope repertoire
errCELL REPORTS MEDICINE
IF10.6
err2024-06-01
err2
errOAAI
errTarke, Alison; Ramezani-Rad, Parham; Neto, Tertuliano Alves Pereira; Lee, Yeji; Silva-Moraes, Vanessa; Goodwin, Benjamin; Bloom, Nathaniel; Siddiqui, Leila; Avalos, Liliana; Frazier, April; Zhang, Zeli; Antunes, Ricardo da Silva; Dan, Jennifer; Crotty, Shane; Grifoni, Alba; Sette, Alessandro
errShare
errSave
Affinity gaps among B cells in germinal centers drive the selection of MPER precursors
errNATURE IMMUNOLOGY
IF27.6
err2024-05-30
err2
errOAAI
errRay, Rashmi; Schiffner, Torben; Wang, Xuesong; Yan, Yu; Rantalainen, Kimmo; Lee, Chang-Chun David; Parikh, Shivang; Reyes, Raphael A.; Dale, Gordon A.; Lin, Ying-Cing; Pecetta, Simone; Giguere, Sophie; Swanson, Olivia; Kratochvil, Sven; Melzi, Eleonora; Phung, Ivy; Madungwe, Lisa; Kalyuzhniy, Oleksandr; Warner, John; Weldon, Stephanie R.; Tingle, Ryan; Lamperti, Edward; Kirsch, Kathrin H.; Phelps, Nicole; Georgeson, Erik; Adachi, Yumiko; Kubitz, Michael; Nair, Usha; Crotty, Shane; Wilson, Ian A.; Schief, William R.; Batista, Facundo D.
errShare
errSave
Vaccination induces broadly neutralizing antibody precursors to HIV gp41
errNATURE IMMUNOLOGY
IF27.6
err2024-05-30
err9
errOAAI
errSchiffner, Torben; Phung, Ivy; Ray, Rashmi; Irimia, Adriana; Tian, Ming; Swanson, Olivia; Lee, Jeong Hyun; Lee, Chang-Chun D.; Marina-Zarate, Ester; Cho, So Yeon; Huang, Jiachen; Ozorowski, Gabriel; Skog, Patrick D.; Serra, Andreia M.; Rantalainen, Kimmo; Allen, Joel D.; Baboo, Sabyasachi; Rodriguez, Oscar L.; Himansu, Sunny; Zhou, Jianfu; Hurtado, Jonathan; Flynn, Claudia T.; Mckenney, Katherine; Havenar-Daughton, Colin; Saha, Swati; Shields, Kaitlyn; Schulze, Steven; Smith, Melissa L.; Liang, Chi-Hui; Toy, Laura; Pecetta, Simone; Lin, Ying-Cing; Willis, Jordan R.; Sesterhenn, Fabian; Kulp, Daniel W.; Hu, Xiaozhen; Cottrell, Christopher A.; Zhou, Xiaoya; Ruiz, Jennifer; Wang, Xuesong; Nair, Usha; Kirsch, Kathrin H.; Cheng, Hwei-Ling; Davis, Jillian; Kalyuzhniy, Oleksandr; Liguori, Alessia; Diedrich, Jolene K.; Ngo, Julia T.; Lewis, Vanessa; Phelps, Nicole; Tingle, Ryan D.; Spencer, Skye; Georgeson, Erik; Adachi, Yumiko; Kubitz, Michael; Eskandarzadeh, Saman; Elsliger, Marc A.; Amara, Rama R.; Landais, Elise; Briney, Bryan; Burton, Dennis R.; Carnathan, Diane G.; Silvestri, Guido; Watson, Corey T.; Yates III, John R.; Paulson, James C.; Crispin, Max; Grigoryan, Gevorg; Ward, Andrew B.; Sok, Devin; Alt, Frederick W.; Wilson, Ian A.; Batista, Facundo D.; Crotty, Shane; Schief, William R.
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errSave

Research Directions

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Co-authors
Cooperation Journals
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I
Ian A. Wilson
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A
Alessandro Sette
H-index: 174 · Papers: 1.4K
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