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M

Manfred Köpf

eth zurich

104H-index
324Paper Count
3.6WCitation Count
Published Papers 140
Publication Date
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RNA-LNP–mediated in vivo prime editing corrects disease phenotypes in a mouse model of citrullinemia type I
errScience Translational Medicine
IF14.6
err2026-05-13
err0
PREAI
errAndrás Tálas; Eleonora I. Ioannidi; Yanik Weber; Tatjana Haenggi; Péter István Kulcsár; Nadia Zürcher; Erica Faccin; Woohyun J. Moon; Lucas Kissling; Elina Andrea Villiger; Mai Matsushita; Tanja Rothgangl; Sharan Janjuha; Paulo J. C. Lin; Martin Poms; Hiromi Muramatsu; Máté Vadovics; Andreas Reichmuth; Manfred Kopf; Norbert Pardi; Ying K. Tam; Johannes Häberle; Gerald Schwank
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errSave
Versatile and Scalable Nanoparticle Vaccine as a Scaffold Against Newly Emerging Influenza Viruses
errViruses
IF3.5
err2026-03-03
err0
errOAAI
errAlessandro Pardini; Dominik A. Rothen; Pascal S. Krenger; Anne-Cathrine Vogt; Romano Josi; Xuelan Liu; Kaspars Tars; Manfred Kopf; Monique Vogel; Martin F. Bachmann
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errSave
A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma
errCancer Cell
IF44.5
err2025-09-28
err0
PREAI
errJohannes Haybaeck; Nicolas Zeller; Monika Julia Wolf; Achim Weber; Ulrich Wagner; Michael Odo Kurrer; Juliane Bremer; Giandomenica Iezzi; Rolf Graf; Pierre-Alain Clavien; Robert Thimme; Hubert Blum; Sergei A. Nedospasov; Kurt Zatloukal; Muhammad Ramzan; Sandra Ciesek; Thomas Pietschmann; Patrice N. Marche; Michael Karin; Manfred Kopf; Jeffrey L. Browning; Adriano Aguzzi; Mathias Heikenwalder
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errSave
GM-CSF derived from alveolar type 2 cells promotes CD301b+ cDC2 generation and allergic airway inflammation
errScience Immunology
IF16.3
err2025-08-08
err0
errOAAI
errJulia Gschwend; Antonie Lechner; Nikolaos D. Sidiropoulos; Paul Maier; Tilde Andersson; Flurin Sturzenegger; Basak Corak; Nina Brander; David A. Bejarano; Elina Wells; Sandra P. Melo; Joana R. D. Martins; Maximilian Nitschké; Ari B. Molofsky; Andreas Schlitzer; Isabelle C. Arnold; Sarah Mundt; Burkhard Becher; Manfred Kopf; Hubert Rehrauer; Christoph Schneider
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errSave
Treatment of a metabolic liver disease in mice with a transient prime editing approach
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2025-05-20
err0
errOAAI
errRothgangl, Tanja; Talas, Andras; Ioannidi, Eleonora I.; Weber, Yanik; Bock, Desiree; Matsushita, Mai; Villiger, Elina Andrea; Schmidheini, Lukas; Moon, Woohyun J.; Lin, Paulo J. C.; Fan, Steven H. Y.; Marquart, Kim F.; Schwerdel, Cornelia; Rimann, Nicole; Faccin, Erica; Villiger, Lukas; Muramatsu, Hiromi; Vadovics, Mate; Cremonesi, Alessio; Kulcsar, Peter Istvan; Thoeny, Beat; Kopf, Manfred; Haberle, Johannes; Pardi, Norbert; Tam, Ying K.; Schwank, Gerald
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errSave
Peroxisomes are critical for a unique metabolic demand and survival of alveolar macrophages
errCELL REPORTS
IF6.9
err2025-05-01
err0
PREAI
errMatsushita, Mai; Muri, Jonathan; Berest, Ivan; Li, Fengqi; Liu, Huan; Corak, Basak; Zamboni, Nicola; Buescher, Joerg; Othman, Alaa; Corrado, Mauro; Cupovic, Jovana; Werner, Sabine; Kovacs, Werner; Kopf, Manfred
errShare
errSave
IL-6 mediates defense against influenza virus by promoting protective antibody responses but not innate inflammation
errMucosal Immunology
IF7.6
err2025-02-18
err0
errOAAI
errF. Piattini; N.D. Sidiropoulos; I. Berest; M. Kopf
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errSave
An Nrf2-NF-KB Crosstalk Controls Hepatocyte Proliferation in the Normal and Injured Liver
errCELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
IF7.4
err2025-02-01
err0
errOAAI
errKuklin, Andrii; Slabber, Coenraad Frederik; Tortola, Luigi; Kwan, Chan Lap; Liebisch, Gerhard; Kondylis, Vangelis; Mair, Florian; Kopf, Manfred; Weber, Achim; Werner, Sabine
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errSave
IL-21/IL-21R signaling renders acute myeloid leukemia stem cells more susceptible to cytarabine treatment and CAR T cell therapy
errCELL REPORTS MEDICINE
IF10.6
err2024-11-01
err0
errOAAI
errRubino, Viviana; Huppi, Michelle; Hopner, Sabine; Tortola, Luigi; Schnuriger, Noah; Legenne, Hugo; Taylor, Lea; Voggensperger, Svenja; Keller, Irene; Bruggman, Remy; Kronig, Marie-Noelle; Bacher, Ulrike; Kopf, Manfred; Ochsenbein, Adrian F.; Riether, Carsten
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errSave
Endothelial metabolic control of insulin sensitivity through resident macrophages
errCELL METABOLISM
IF30.9
err2024-11-01
err0
errOAAI
errZhang, Jing; Sjoberg, Kim Anker; Gong, Songlin; Wang, Tongtong; Li, Fengqi; Kuo, Andrew; Durot, Stephan; Majcher, Adam; Ardicoglu, Raphaela; Desgeorges, Thibaut; Mann, Charlotte Greta; Arnaiz, Ines Soro; Fitzgerald, Gillian; Gilardoni, Paola; Abel, E. Dale; Kon, Shigeyuki; Olivares-Villagomez, Danyvid; Zamboni, Nicola; Wolfrum, Christian; Hornemann, Thorsten; Morscher, Raphael; Tisch, Nathalie; Ghesquiere, Bart; Kopf, Manfred; Richter, Erik A.; De Bock, Katrien
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errSave
Inflammatory Mediators Suppress FGFR2 Expression in Human Keratinocytes to Promote Inflammation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2024-09-28
err1
errOAAI
errFerrarese, Luca; Koch, Michael; Baumann, Artemis; Bento-Lopes, Liliana; Wust, Daria; Berest, Ivan; Kopf, Manfred; Werner, Sabine
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errSave
Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs
errNATURE METHODS
IF32.1
err2024-09-23
err1
PREAI
errMarquart, Kim Fabiano; Mathis, Nicolas; Mollaysa, Amina; Mueller, Saphira; Kissling, Lucas; Rothgangl, Tanja; Schmidheini, Lukas; Kulcsar, Peter Istvan; Allam, Ahmed; Kaufmann, Masako M.; Matsushita, Mai; Haenggi, Tatjana; Cathomen, Toni; Kopf, Manfred; Krauthammer, Michael; Schwank, Gerald
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errSave
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation
errNATURE IMMUNOLOGY
IF27.6
err2024-04-26
err6
errOAAI
errTheobald, H.; Bejarano, D. A.; Katzmarski, N.; Haub, J.; Schulte-Schrepping, J.; Yu, J.; Bassler, K.; Ament, A. L.; Osei-Sarpong, C.; Piattini, F.; Vornholz, L.; T'Jonck, W.; Gyoerfi, A. H.; Hayer, H.; Yu, X.; Sheoran, S.; Al Jawazneh, A.; Chakarov, S.; Haendler, K.; Brown, G. D.; Williams, D. L.; Bosurgi, L.; Distler, J. H. W.; Ginhoux, F.; Ruland, J.; Beyer, M. D.; Greter, M.; Bain, C. C.; Vazquez-Armendariz, A. I.; Kopf, M.; Schultze, J. L.; Schlitzer, A.
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errSave
A guideline on the molecular ecosystem regulating ferroptosis
errNATURE CELL BIOLOGY
IF19.1
err2024-02-29
err53
PREAI
errDai, Enyong; Chen, Xin; Linkermann, Andreas; Jiang, Xuejun; Kang, Rui; Kagan, Valerian E.; Bayir, Huelya; Yang, Wan Seok; Garcia-Saez, Ana J.; Ioannou, Maria S.; Janowitz, Tobias; Ran, Qitao; Gu, Wei; Gan, Boyi; Krysko, Dmitri V.; Zhu, Xiaofeng; Wang, Jiayi; Krautwald, Stefan; Toyokuni, Shinya; Xie, Yangchun; Greten, Florian R.; Yi, Qing; Schick, Joel; Liu, Jiao; Gabrilovich, Dmitry I.; Liu, Jinbao; Zeh, Herbert J.; Zhang, Donna D.; Yang, Minghua; Iovanna, Juan; Kopf, Manfred; Adolph, Timon E.; Chi, Jen-Tsan; Li, Changfeng; Ichijo, Hidenori; Karin, Michael; Sankaran, Vijay G.; Zou, Weiping; Galluzzi, Lorenzo; Bush, Ashley I.; Li, Binghui; Melino, Gerry; Baehrecke, Eric H.; Lotze, Michael T.; Klionsky, Daniel J.; Stockwell, Brent R.; Kroemer, Guido; Tang, Daolin
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errSave
The role of recruitment versus training in influenza-induced lasting changes to alveolar macrophage function
errNATURE IMMUNOLOGY
IF27.6
err2023-08-28
err7
errOAAI
errIliakis, Chrysante S.; Kulikauskaite, Justina; Aegerter, Helena; Li, Fengqi; Piattini, Federica; Jakubzick, Claudia V.; Guilliams, Martin; Kopf, Manfred; Wack, Andreas
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errSave
Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form
errNATURE IMMUNOLOGY
IF27.6
err2023-02-13
err6
PREAI
errZewinger, Stephen; Reiser, Jochen; Jankowski, Vera; Alansary, Dalia; Hahm, Eunsil; Triem, Sarah; Klug, Mira; Schunk, Stefan J.; Schmit, David; Kramann, Rafael; Koerbel, Christina; Ampofo, Emmanuel; Laschke, Matthias W.; Selejan, Simina-Ramona; Paschen, Anna; Herter, Tobias; Gaul, Susanne; Silbernagel, Guenther; Sester, Martina; Sester, Urban; Assmann, Gunter; Bals, Robert; Kostner, Gerhard; Jahnen-Dechent, Willi; Menger, Michael D.; Rohrer, Lucia; Maerz, Winfried; Boehm, Michael; Jankowski, Joachim; Kopf, Manfred; Latz, Eicke; Niemeyer, Barbara A.; Fliser, Danilo; Laufs, Ulrich; Speer, Thimoteus
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errSave
A Protumorigenic mDia2-MIRO1 Axis Controls Mitochondria! Positioning and Function in Cancer-Associated Fibroblasts
errCANCER RESEARCH
IF16.6
err2022-08-23
err8
errOAAI
errCangkrama, Michael; Liu, Huan; Whipman, James; Zubair, Maria; Matsushita, Mai; Di Filippo, Michela; Kopf, Manfred; Innocenti, Metello; Werner, Sabine
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errSave
Monocyte-derived alveolar macrophages autonomously determine severe outcome of respiratory viral infection
errSCIENCE IMMUNOLOGY
IF16.3
err2022-07-29
err63
errOAAI
errLi, Fengqi; Piattini, Federica; Pohlmeier, Lea; Feng, Qian; Rehrauer, Hubert; Kopf, Manfred
errShare
errSave
High-resolution profiling of MHC II peptide presentation capacity reveals SARS-CoV-2 CD4 T cell targets and mechanisms of immune escape
errSCIENCE ADVANCES
IF12.5
err2022-04-29
err18
errOAAI
errObermair, Franz-Josef; Renoux, Florian; Heer, Sebastian; Lee, Chloe H.; Cereghetti, Nastassja; Loi, Marisa; Maestri, Giulia; Haldner, Yannick; Wuigk, Robin; Iosefson, Ohad; Patel, Pooja; Triebel, Katherine; Kopf, Manfred; Swain, Joanna; Kisielow, Jan
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errSave
Gene therapy of Csf2ra deficiency in mouse fetal monocyte precursors restores alveolar macrophage development and function
errJCI INSIGHT
IF6.1
err2022-04-08
err5
errOAAI
errLi, Fengqi; Okreglicka, Katarzyna Maria; Piattini, Federica; Pohlmeier, Lea Maria; Schneider, Christoph; Kopf, Manfred
errShare
errSave

Research Directions

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Co-authors
Cooperation Journals
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H-index: 174 · Papers: 1.6K
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H-index: 165 · Papers: 1.0K
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