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Robert A. Bonomo

case western reserve university school of medicine

115H-index
1.1KPaper Count
6.1WCitation Count
Published Papers 586
Publication Date
Boronic Acid Inhibitors of β-Lactamases: A Promising Strategy Against Antimicrobial Resistance
err2026-08-15
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errOAAI
errNicolò Santi; Federico Corsini; Robert A. Bonomo; Emilia Caselli; Fabio Prati
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Role of Ambler Position 104 in Defining Substrate Specificity in the KPC Family of β-Lactamases
err2026-04-01
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errOAAI
errGao, Lin; Marshall, Steven; Bethel, Christopher R.; Hujer, Andrea M.; Taracila, Magdalena A.; Hujer, Kristine M.; Haider, Shozeb; Bonomo, Robert A.
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Structural and Kinetic Basis for the Rational Design of Next-Generation β-Lactamase Inhibitors
err2026-03-16
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errOAAI
errShuang Chen; Muchen Yu; Manming Xu; Sergio Decherchi; Magdalena A. Taracila; Andrea M. Hujer; Christopher R. Bethel; Robert A. Bonomo; Shozeb Haider
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Cryptic Binding Pockets in PDC-3 β-Lactamase Modulate Resistance Profiles
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IF8.7
err2026-02-20
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errOAAI
errShuang Chen; Fedaa Attana; Andrea M. Hujer; Christopher R. Bethel; Magdalena A. Taracila; Robert A. Bonomo; Shozeb Haider
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Exploring the activity of a novel orally bioavailable β-lactam-β-lactamase inhibitor combination, ceftibuten-ledaborbactam, against Enterobacterales-carrying blaOXA-48
err2025-12-01
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PREAI
errMojica, Maria F.; Zeiser, Elise T.; Becka, Scott A.; Six, David A.; Moeck, Greg; Bonomo, Robert A.; Papp-Wallace, Krisztina M.
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Zinc starvation uncovers bacterial host-specific proteases that shape NDM adaptability in Acinetobacter baumannii
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IF4.7
err2025-12-01
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PREAI
errParodi, Clarisa; Saposnik, Lucas; Martino, Roman A.; Ramirez, Maria Soledad; Cassataro, Juliana; Smania, Andrea M.; Bonomo, Robert A.; Vila, Alejandro J.; Gonzalez, Lisandro J.
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Let’s Dance: How Protein Dynamics Drive β-Lactamase Evolution and Antibiotic Resistance?
err2025-11-05
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PREAI
errBrenda A. Warecki; Diego M. Moreno; Robert A. Bonomo; Alejandro J. Vila
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Ampicillin/Sulbactam in Combination with Ceftazidime/Avibactam Against Metallo-β-Lactamase-Producing Carbapenem-Resistant Acinetobacter baumannii: A Genomics-Informed Mechanism-based model
err2025-11-01
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errArun, Bhavatharini; Liu, Eloise; Valle, Quentin; Sharma, Rajnikant; Bui, Ngoc Minh; Mezcord, Vyanka; Luu, Irene; Traglia, German Matias; Pasteran, Fernando; Paterson, David; Bonomo, Robert A.; Ramirez, Maria Soledad; Rao, Gauri G.
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The Role of β-Lactam Antibiotics in Treating Mycobacterium abscessus: From Laboratory Insights to Clinical Applications and the Case for Clinical Trials
err2025-10-01
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errOAAI
errDousa, Khalid M.; Shin, Eunjeong; Kurz, Sebastian G.; Rubin, Eric J.; Holland, Steven M.; Olivier, Kenneth N.; Daley, Charles L.; Kreiswirth, Barry N.; Pottinger, Paul S.; Bonomo, Robert A.
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Performance evaluation of a rapid, universal and automation amenable sepsis diagnostic workflow that identifies pathogens and determines their antimicrobial resistance directly from whole blood
err2025-10-01
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errOAAI
errRamya, V. M.; Sharma, Divya Khandige; Sampath, Rangarajan; Carpenter, Megan; Chakraborty, Ishita; Hall, Thomas A.; Mosel, Michael; Hannis, James; Risen, Lisa; Marzan, Christine; Bonomo, Robert
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Genomic insights of two Acinetobacter non-baumannii strains with uncommon mechanisms of resistance leading to cefiderocol resistance
err2025-09-16
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errOAAI
errUsman Akhtar; Samyar Moheb; Carol Davies-Sala; Joshua Gutierrez; Fernando Pasteran; Marisel R. Tuttobene; Tomás Subils; Chun Fu Cheng; Quentin Valle; Rajnikant Sharma; Marcelo E. Tolmasky; Gauri Rao; Robert A. Bonomo; German M. Traglia; María Soledad Ramírez
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Mechanistic basis for inhibition of the extended-spectrum β-lactamase GES-1 by enmetazobactam and tazobactam
err2025-09-01
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errBeer, Michael; Hinchliffe, Philip; Hanzevacki, Marko; Bethel, Christopher R.; Tooke, Catherine L.; van der Kamp, Marc W.; Papp-Wallace, Krisztina M.; Bonomo, Robert A.; Shapiro, Stuart; Mulholland, Adrian J.; Spencer, James
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Spontaneous Emergence of Cefiderocol Resistance in Klebsiella pneumoniae KPC-163: Genomic and Transcriptomic Insights
err2025-08-16
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errOAAI
errIrene Luu; Vyanka Mezcord; Jenny Escalante; German M. Traglia; Marisel R. Tuttobene; Cecilia Rodriguez; Chun Fu Cheng; Quentin Valle; Rajnikant Sharma; Marcelo E. Tolmasky; Robert A. Bonomo; Gauri Rao; Fernando Pasteran; Maria Soledad Ramirez
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NDM-driven cefiderocol resistance: effect and therapeutic considerations
err2025-08-11
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PREAI
errBrenda A Warecki; Pranita D Tamma; Robert A Bonomo; Alejandro J Vila
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Inhibitor Affinity Differs among Clinical Variants of IMP Metallo-β-Lactamases: Analysis and Implications for Inhibitor Design
err2025-07-24
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PREAI
errCaitlyn A. Thomas; John Paul Alao; Thomas Smisek; Zishuo Cheng; Christopher R. Bethel; Kundi Yang; Ikponwmosa Obaseki; Richard C. Page; Robert A. Bonomo; Peter Oelschlaeger; Walter Fast; Andrea N. Kravats; Michael W. Crowder
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Emerging Resistance to Novel β-Lactam β-Lactamase Inhibitor Combinations in Klebsiella pneumoniae bearing KPC Variants
err2025-07-14
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errMase Hamza; German M. Traglia; Lucia Maccari; Sonia Gomez; Maria Belen Sanz; Usman Akhtar; Vyanka Mezcord; Jenny Escalante; Alejandra Corso; Cecilia Rodriguez; Christopher R. Bethel; Gauri G. Rao; Marcelo E. Tolmasky; David Paterson; Robert A. Bonomo; Fernando Pasteran; Maria Soledad Ramirez
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Resistance to oxyimino-cephalosporins conferred by an alternative mechanism of hydrolysis by the Acinetobacter-derived cephalosporinase-33 (ADC-33), a class C β-lactamase present in carbapenem-resistant Acinetobacter baumannii (CRAb)
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IF4.7
err2025-06-11
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errPowers, Rachel A.; Wallar, Bradley J.; Jarvis, Hannah R.; Ziegler, Zoe X.; June, Cynthia M.; Bethel, Christopher R.; Hujer, Andrea M.; Taracila, Magdalena A.; Rudin, Susan D.; Hujer, Kristine M.; Prati, Fabio; Caselli, Emilia; Bonomo, Robert A.
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Impact of the double deletion ΔG242-T243 in KPC-2 in the effectiveness of ceftazidime-avibactam and imipenem-relebactam
err2025-06-04
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errBrunetti, Florencia; Gutkind, Gabriel; Gao, Lin; Haider, Shozeb; Bonomo, Robert A.; Power, Pablo
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Escherichia coli producing AmpC DHA-1 bacteraemia in neutropenic leukemic patient: continuous infusion ceftazidime/avibactam as a carbapenem sparing regimen
err2025-06-01
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PREAI
errGiuliano, S.; Piccirilli, A.; Angelini, J.; Patriarca, F.; Fanin, R.; Martini, L.; Semenzin, T.; Fanin, M.; Lanini, S.; Bonomo, R. A.; Perilli, M.; Tascini, C.
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Revisiting REVISIT: The Case for Ceftazidime/Avibactam Plus Aztreonam
err2025-06-01
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PREAI
errTamma, Pranita D.; Lodise, Thomas P.; Mojica, Maria F.; Perez, Federico; Bonomo, Robert A.
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