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J

John A. Katzenellenbogen

chemistry

100H-index
1.0KPaper Count
4.2WCitation Count
Published Papers 309
Publication Date
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JAK/STAT1-interferon-ISGylation networks in breast cancer resistance to inhibitors of FOXM1 and CDK4/6
errnpj Breast Cancer
IF7.6
err2026-02-12
err0
errOAAI
errYvonne Ziegler; Sandeep Kumar; Carlos M. Saeh; Blake N. Plotner; Grace O. Pento; Sung Hoon Kim; Alekya Raghavan; Rachel Schiff; John A. Katzenellenbogen; Benita S. Katzenellenbogen
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Targeting FOXM1 reshapes antitumor immunity to attenuate small cell lung cancer progression
errCancer Letters
IF10.1
err2025-11-21
err0
PREAI
errMd Arafat Khan; Parvez Khan; Mahek Fatima; Asad Ur Rehman; Laiba Anwar; Zahraa Wajih Alsafwani; Aatiya Ahmad; Mohammad Ali Abbas Zaidi; Jesse L. Cox; Areem Zahid; Sameer Mohiuddin; Sung Hoon Kim; Juan A. Santamaria-Barria; Imayavaramban Lakshmanan; Benita S. Katzenellenbogen; John A. Katzenellenbogen; Apar K. Ganti; Surinder K. Batra; Mohd Wasim Nasser
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errSave
Chloroindazole based estrogen receptor β ligands with favorable pharmacokinetics promote functional remyelination and visual recovery
errScientific Reports
IF3.9
err2025-10-08
err0
errOAAI
errMicah Feri; Sung Hoon Kim; Flavio D. Cardenas; Alyssa M. Anderson; Brandon T. Poole; Devang Deshpande; Shane Desfor; Kelley C. Atkinson; Stephanie R. Peterson; Kendall W. Nettles; Jerome C. Nwachukwu; Moyinoluwa T. Ajayi; Fernando Beltran; David E. Martin; Julio Tapia; Carol D. Curtis; Martin I. Garcia-Castro; Benita S. Katzenellenbogen; John A. Katzenellenbogen; Seema K. Tiwari-Woodruff
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Benzestrol Isomer Stereochemistry Determines the Distinct Estrogenic Activities and Conformations of the Eight Isomers When Bound to Estrogen Receptor α
errACS Pharmacology & Translational Science
IF3.7
err2025-07-09
err0
errOAAI
errYingwei Hou; Jerome C. Nwachukwu; Kathryn Carlson; Sung Hoon Kim; Samantha Angle; Eric N. Jacobsen; Toby Woods; Sofia L. Mateus; Sean W. Fanning; Yvonne Ziegler; Benita S. Katzenellenbogen; Kendall W. Nettles; John A. Katzenellenbogen
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Phthalates Impair Estrogenic Regulation of HIF2α and Extracellular Vesicle Secretion by Human Endometrial Stromal Cells
errENDOCRINOLOGY
IF3.3
err2025-05-05
err0
errOAAI
errBeal, Jacob R.; Bhurke, Arpita; Carlson, Kathryn E.; Katzenellenbogen, John A.; Yu, Jie; Flaws, Jodi A.; Bagchi, Indrani C.; Bagchi, Milan K.
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errSave
Discovery of ERD-12310A as an Exceptionally Potent and Orally Efficacious PROTAC Degrader of Estrogen Receptor α (ERα)
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-11-25
err0
PREAI
errRej, Rohan Kalyan; Hu, Biao; Chen, Zhixiang; Acharyya, Ranjan Kumar; Wu, Dimin; Metwally, Hoda; Mceachern, Donna; Wang, Yu; Jiang, Wei; Bai, Longchuan; Nishimura, Leticia S.; Gersch, Christina L.; Wang, Meilin; Wen, Bo; Sun, Duxin; Carlson, Kathryn; Katzenellenbogen, John A.; Xu, Guozhang; Zhang, Weihong; Wu, Wenxue; Priestley, E. Scott; Sui, Zhihua; Rae, James M.; Wang, Shaomeng
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Nuclear Receptor NR2E3 Activates Both Wild-Type and Mutated p53 in Multiple Myeloma Cells
errBLOOD
IF23.1
err2024-11-05
err1
PREAI
errWen, Zhi; Bissonnette, Adam; Moat, Luke F.; Wang, Yidan; Katzenellenbogen, Benita S.; Katzenellenbogen, John A.; Kim, Sung Hoon; Shour, Abdul; Onitilo, Adedayo A.
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errSave
Iterative Catalyst-Controlled Diastereoselective Matteson Homologations Enables the Selective Synthesis of Benzestrol Isomers
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-10-31
err0
PREAI
errAngle, Samantha R.; Sharma, Hayden A.; Choi, Christie K.; Carlson, Kathryn E.; Hou, Yingwei; Nwachukwu, Jerome C.; Kim, Sung Hoon; Katzenellenbogen, Benita S.; Nettles, Kendall W.; Katzenellenbogen, John A.; Jacobsen, Eric N.
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errSave
Resistance to FOXM1 inhibitors in breast cancer is accompanied by impeding ferroptosis and apoptotic cell death
errBREAST CANCER RESEARCH AND TREATMENT
IF3
err2024-07-09
err2
errOAAI
errKumar, Sandeep; Ziegler, Yvonne; Plotner, Blake N.; Flatt, Kristen M.; Kim, Sung Hoon; Katzenellenbogen, John A.; Katzenellenbogen, Benita S.
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errSave
Asymmetric allostery in estrogen receptor-α homodimers drives responses to the ensemble of estrogens in the hormonal milieu
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-06-03
err1
errOAAI
errMin, Charles K.; Nwachukwu, Jerome C.; Hou, Yingwei; Russo, Robin J.; Papa, Alexandra; Min, Jian; Peng, Rouming; Kim, Sung Hoon; Ziegler, Yvonne; Rangarajan, Erumbi S.; Izard, Tina; Katzenellenbogen, Benita S.; Katzenellenbogen, John A.; Nettles, Kendall W.
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NB compounds are potent and efficacious FOXM1 inhibitors in high-grade serous ovarian cancer cells
errJOURNAL OF OVARIAN RESEARCH
IF4.2
err2024-05-04
err4
errOAAI
errLiu, Cassie; Vorderbruggen, Makenzie; Munoz-Trujillo, Catalina; Kim, Sung Hoon; Katzenellenbogen, John A.; Katzenellenbogen, Benita S.; Karpf, Adam R.
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errSave
An Emerging Class of ER mutations Enhances ER Dimerization and Promotes ER Activity
errCANCER RESEARCH
IF16.6
err2024-05-02
err0
PREAI
errIrani, Seema; Tan, Wuwei; Li, Qing; Toy, Weiyi; Jones, Catherine; Gadiya, Mayur; Marra, Antonio; Katzenellenbogen, John; Carlson, Kathryn; Katzenellenbogen, Benita S.; Shen, Yang; Chandarlapaty, Sarat
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errSave
Development of folate receptor alpha targeted FOXM1 inhibitors for ovarian cancer
errCANCER RESEARCH
IF16.6
err2024-03-04
err0
PREAI
errKarpf, Adam R.; Vorderbruggen, Makenzie; Rikhtechi, Pedram; Munoz-Trujillo, Catalina; Liu, Cassie; Matherly, Larry H.; Kim, Sung Hoon; Katzenellenbogen, Benita S.; Katzenellenbogen, John A.; Garrison, Jered C.
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errSave
Somatic estrogen receptor α mutations that induce dimerization promote receptor activity and breast cancer proliferation
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2024-01-02
err6
errOAAI
errIrani, Seema; Tan, Wuwei; Li, Qing; Toy, Weiyi; Jones, Catherine; Gadiya, Mayur; Marra, Antonio; Katzenellenbogen, John A.; Carlson, Kathryn E.; Katzenellenbogen, Benita S.; Karimi, Mostafa; Rajappachetty, Ramya Segu; Priore, Isabella S. Del; Reis-Filho, Jorge S.; Shen, Yang; Chandarlapaty, Sarat
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errSave
Reprogramming of endothelial gene expression by tamoxifen inhibits angiogenesis and ERα-negative tumor growth
errTHERANOSTICS
IF13.3
err2024-01-01
err0
errOAAI
errFebrissy, Chanaelle; Adlanmerini, Marine; Pequeux, Christel; Boudou, Frederic; Buscato, Melissa; Gargaros, Adrien; Gilardi-Bresson, Silveric; Boriak, Khrystyna; Laurell, Henrik; Fontaine, Coralie; Katzenellenbogen, Benita S.; Katzenellenbogen, John A.; Guillermet-Guibert, Julie; Arnal, Jean-Francois; Metivier, Raphael; Lenfant, Francoise
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errSave
ESR1 F404 Mutations and Acquired Resistance to Fulvestrant in ESR1-Mutant Breast Cancer
errCANCER DISCOVERY
IF33.3
err2023-11-17
err8
errOAAI
errKingston, Belinda; Pearson, Alex; Herrera-Abreu, Maria Teresa; Sim, Li-Xuan; Cutts, Rosalind J.; Shah, Heena; Moretti, Laura; Kilburn, Lucy S.; Johnson, Hannah; Macpherson, Iain R.; Ring, Alistair; Bliss, Judith M.; Hou, Yingwei; Toy, Weiyi; Katzenellenbogen, John A.; Chandarlapaty, Sarat; Turner, Nicholas C.
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Endothelial ERα promotes glucose tolerance by enhancing endothelial insulin transport to skeletal muscle
errNATURE COMMUNICATIONS
IF15.7
err2023-08-17
err7
errOAAI
errSacharidou, Anastasia; Chambliss, Ken; Peng, Jun; Barrera, Jose; Tanigaki, Keiji; Luby-Phelps, Katherine; Ozdemir, Ipek; Khan, Sohaib; Sirsi, Shashank R.; Kim, Sung Hoon; Katzenellenbogen, Benita S.; Katzenellenbogen, John A.; Kanchwala, Mohammed; Sathe, Adwait A.; Lemoff, Andrew; Xing, Chao; Hoyt, Kenneth; Mineo, Chieko; Shaul, Philip W.
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errSave
Targeting the oncogenic transcription factor FOXM1 to improve outcomes in all subtypes of breast cancer
errBREAST CANCER RESEARCH
IF5.6
err2023-06-27
err34
errOAAI
errKatzenellenbogen, Benita S.; Guillen, Valeria Sanabria; Katzenellenbogen, John A.
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errSave
NB compound FOXM1 inhibitors have potent anti-cancer activity in high-grade serous ovarian carcinoma
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errVorderbruggen, Makenzie; Liu, Cassie; Trujillo, Catalina Munoz; Kim, Sung Hoon; Katzenellenbogen, John A.; Katzenellenbogen, Benita S.; Karpf, Adam R.
errShare
errSave
FOXM1 inhibition: A novel therapeutic approach for small cell lung cancer
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errKhan, Md Arafat; Khan, Parvez; Fatima, Mahek; Rehman, Asad Ur; Maurya, Shailendra Kumar; Mohiuddin, Sameer; Venkata, Ramakanth Chirravuri; Cox, Jesse L.; Kim, Sung Hoon; Katzenellenbogen, Benita S.; Katzenellenbogen, John A.; Ganti, Apar K.; Batra, Surinder K.; Nasser, Mohd Wasim
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Research Directions

No research directions
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