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Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis Al Bakir, Ibrahim; Curtius, Kit; Cresswell, George D.; Grant, Heather E.; Nasreddin, Nadia; Smith, Kane; Nowinski, Salpie; Guo, Qingli; Belnoue-Davis, Hayley L.; Fisher, Jennifer; Clarke, Theo; Kimberley, Christopher; Mossner, Maximilian; Dunne, Philip D.; Loughrey, Maurice B.; Speight, Ally; East, James E.; Wright, Nicholas A.; Rodriguez-Justo, Manuel; Jansen, Marnix; Moorghen, Morgan; Baker, Ann-Marie; Leedham, Simon J.; Hart, Ailsa L.; Graham, Trevor A. Share Save
Tumour purity assessment with deep learning in colorectal cancer and impact on molecular analysis Schoenpflug, Lydia A.; Chatzipli, Aikaterini; Sirinukunwattana, Korsuk; Richman, Susan; Blake, Andrew; Robineau, James; Mertz, Kirsten D.; Verrill, Clare; Leedham, Simon J.; Hardy, Claire; Whalley, Celina; Redmond, Keara; Dunne, Philip; Walker, Steven; Beggs, Andrew D.; Mcdermott, Ultan; Murray, Graeme, I; Samuel, Leslie M.; Seymour, Matthew; Tomlinson, Ian; Quirke, Philip; S CORT Consortium, Jens; Rittscher, Jens; Maughan, Tim; Domingo, Enric; Koelzer, Viktor H. Share Save
Update from 2010 (standard operating procedure): protocol for the 2024 British Society of Gastroenterology Guidelines on colorectal surveillance in inflammatory bowel disease Gordon, Morris; Nigam, Gaurav Bhaskar; Sinopoulou, Vassiliki; Al Bakir, Ibrahim; Bateman, Adrian C.; Din, Shahida; Dolwani, Sunil; Dhar, Anjan; Faiz, O. D.; Hayee, Bu; Healey, Chris; Lamb, Christopher Andrew; Leedham, Simon; Kabir, Misha; Iacucci, Marietta; Hart, Ailsa; Morris, A. John; Novelli, Marco; Raine, Tim; Rutter, Matt; Shepherd, Neil A.; Subramanian, Venkataraman; Trudgill, Nigel J.; Vance, Maggie; Wilson, Ana; White, Lydia; Wakeman, Ruth; East, James E. Share Save
Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1 (vol 133, e168277, 2023) Beach, Callum; MacLean, David; Majorova, Dominika; Melemenidis, Stavros; Nambiar, Dhanya K.; Kim, Ryan K.; Valbuena, Gabriel N.; Guglietta, Silvia; Krieg, Carsten; Darvish-Damavandi, Mahnaz; Suwa, Tatsuya; Easton, Alistair; Hillson, Lily V. S.; McCulloch, Ashley K.; McMahon, Ross K.; Pennel, Kathryn; Edwards, Joanne; O'Cathail, Sean M.; Roxburgh, Campbell S.; Domingo, Enric; Moon, Eui Jung; Jiang, Dadi; Jiang, Yanyan; Zhang, Qingyang; Koong, Albert C.; Woodruff, Trent M.; Graves, Edward E.; Maughan, Tim; Buczacki, Simon J. A.; Stucki, Manuel; Le, Quynh-Thu; Leedham, Simon J.; Giaccia, Amato J.; Olcina, Monica M. Share Save
Identi fi cation and validation of a machine learning model of complete response to radiation in rectal cancer reveals immune in fi ltrate and TGF P as key predictors Domingo, Enric; Rathee, Sanjay; Blake, Andrew; Samuel, Leslie; Murray, Graeme; Sebag-Montefiore, David; Gollins, Simon; West, Nicholas; Begum, Rubina; Richman, Susan; Quirke, Phil; Redmond, Keara; Chatzipli, Aikaterini; Barberis, Alessandro; Hassanieh, Sylvana; Mahmood, Umair; Youdell, Michael; McDermott, Ultan; Koelzer, Viktor; Leedham, Simon; Tomlinson, Ian; Dunne, Philip; Buffa, Francesca M.; Maughan, Timothy S. Share Save
Molecular mechanism of BMP signal control by Twisted gastrulation Malinauskas, Tomas; Moore, Gareth; Rudolf, Amalie F.; Eggington, Holly; Belnoue-Davis, Hayley L.; El Omari, Kamel; Griffiths, Samuel C.; Woolley, Rachel E.; Duman, Ramona; Wagner, Armin; Leedham, Simon J.; Baldock, Clair; Ashe, Hilary L.; Siebold, Christian Share Save
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer (Vol 56, pg 458, 2024) Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; McCooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D. Share Save
Poor Diagnostic Reproducibility in the Identification of Nonconventional Dysplasia in Colitis Impacts the Application of Histologic Stratification Tools Nasreddin, Nadia; Jansen, Marnix; Loughrey, Maurice B.; Wang, Lai Mun; Koelzer, Viktor H.; Rodriguez-Justo, Manuel; Novelli, Marco; Fisher, Jennifer; Brown, Matthew W.; Al Bakir, Ibrahim; Hart, Ailsa L.; Dunne, Philip; Graham, Trevor A.; Leedham, Simon J. Share Save
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; Mccooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D. Share Save
Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1 Beach, Callum; MacLean, David; Majorova, Dominika; Melemenidis, Stavros; Nambiar, Dhanya K.; Kim, Ryan K.; Valbuena, Gabriel N.; Guglietta, Silvia; Krieg, Carsten; Darvish-Damavandi, Mahnaz; Suwa, Tatsuya; Easton, Alistair; Hillson, Lily V. S.; McCulloch, Ashley K.; McMahon, Ross K.; Pennel, Kathryn; Edwards, Joanne; O'Cathail, Sean M.; Roxburgh, Campbell S.; Domingo, Enric; Moon, Eui Jung; Jiang, Dadi; Jiang, Yanyan; Zhang, Qingyang; Koong, Albert C.; Woodruff, Trent M.; Graves, Edward E.; Maughan, Tim; Buczacki, Simon J. A.; Stucki, Manuel; Le, Quynh-Thu; Leedham, Simon J.; Giaccia, Amato J.; Olcina, Monica M. Share Save
Virtual alignment of pathology image series for multi-gigapixel whole slide images Gatenbee, Chandler D.; Baker, Ann-Marie; Prabhakaran, Sandhya; Swinyard, Ottilie; Slebos, Robbert J. C.; Mandal, Gunjan; Mulholland, Eoghan; Andor, Noemi; Marusyk, Andriy; Leedham, Simon; Conejo-Garcia, Jose R.; Chung, Christine H.; Robertson-Tessi, Mark; Graham, Trevor A.; Anderson, Alexander R. A. Share Save
Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features Flanagan, Dustin J.; Amirkhah, Raheleh; Vincent, David F.; Gunduz, Nuray; Gentaz, Pauline; Cammareri, Patrizia; McCooey, Aoife J.; McCorry, Amy M. B.; Fisher, Natalie C.; Davis, Hayley L.; Ridgway, Rachel A.; Lohuis, Jeroen; Leach, Joshua D. G.; Jackstadt, Rene; Gilroy, Kathryn; Mariella, Elisa; Nixon, Colin; Clark, William; Hedley, Ann; Markert, Elke K.; Strathdee, Douglas; Bartholin, Laurent; Redmond, Keara L.; Kerr, Emma M.; Longley, Daniel B.; Ginty, Fiona; Cho, Sanghee; Coleman, Helen G.; Loughrey, Maurice B.; Bardelli, Alberto; Maughan, Timothy S.; Campbell, Andrew D.; Lawler, Mark; Leedham, Simon J.; Barry, Simon T.; Inman, Gareth J.; van Rheenen, Jacco; Dunne, Philip D.; Sansom, Owen J. Share Save
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia (vol 29, pg 1213, 2022) Vazquez, Ester Gil; Nasreddin, Nadia; Valbuena, Gabriel N.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Eggington, Holly R.; Schenck, Ryan O.; Wouters, Valerie M.; Wirapati, Pratyaksha; Gilroy, Kathryn; Lannagan, Tamsin R. M.; Flanagan, Dustin J.; Najumudeen, Arafath K.; Omwenga, Sulochana; McCorry, Amy M. B.; Easton, Alistair; Koelzer, Viktor H.; East, James E.; Morton, Dion; Trusolino, Livio; Maughan, Timothy; Campbell, Andrew D.; Loughrey, Maurice B.; Dunne, Philip D.; Tsantoulis, Petros; Huels, David J.; Tejpar, Sabine; Sansom, Owen J.; Leedham, Simon J. Share Save
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