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S

S. Cusack

institut pasteur paris

92H-index
524Paper Count
2.8WCitation Count
Published Papers 129
Publication Date
Polymerase trapping as the mechanism of H5 highly pathogenic avian influenza virus genesis
errScience
IF45.8
err2026-03-12
err0
PREAI
errMathis Funk; Monique I. Spronken; Roy M. Hutchinson; Benoit Arragain; Pauline Juyoux; Theo M. Bestebroer; Anja C. M. de Bruin; Alexander P. Gultyaev; Ron A. M. Fouchier; Stephen Cusack; Aartjan J. W. te Velthuis; Mathilde Richard
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Mechanism of co-transcriptional cap snatching by influenza polymerase
errNature
IF48.5
err2026-03-01
err0
PREAI
errRotsch, Alexander Helmut; Li, Delong; Dupont, Maud; Krischuns, Tim; Neef, Ute; Oberthur, Christiane; Stelfox, Alice; Lukarska, Maria; Fianu, Isaac; Lidschreiber, Michael; Naffakh, Nadia; Dienemann, Christian; Cusack, Stephen; Cramer, Patrick
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Structure of the tilapia lake virus nucleoprotein bound to RNA
err2025-02-24
err0
errOAAI
errArragain, Benoit; Pelosse, Martin; Huard, Karine; Cusack, Stephen
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The RNA receptor RIG-I binding synthetic oligodeoxynucleotide promotes survival
err2024-11-08
err0
errOAAI
errWang, Yongxing; V. Kulkarni, Vikram; Pantaleongarcia, Jezreel; Longmire, Michael K.; Lethier, Mathilde; Cusack, Stephen; Evans, Scott E.
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4-Anilinoquinazoline Derivatives as the First Potent NOD1-RIPK2 Signaling Pathway Inhibitors at the Nanomolar Range
err2024-10-24
err1
PREAI
errBarczyk, Amclie; Six, Perrine; Rivoal, Morgane; Devos, Claire; Dezitter, Xavier; Cornu-Choi, Min-Jeong; Huard, Karine; Pellegrini, Erika; Cusack, Stephen; Dubuquoy, Laurent; Millet, Regis; Leleu-Chavain, Natascha
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The molecular dissection of TRIM25's RNA-binding mechanism provides key insights into its antiviral activity
err2024-10-01
err0
errOAAI
errAlvarez, Lucia; Haubrich, Kevin; Iselin, Louisa; Gillioz, Laurent; Ruscica, Vincenzo; Lapouge, Karine; Augsten, Sandra; Huppertz, Ina; Choudhury, Nila Roy; Simon, Bernd; Masiewicz, Pawel; Lethier, Mathilde; Cusack, Stephen; Rittinger, Katrin; Gabel, Frank; Leitner, Alexander; Michlewski, Gracjan; Hentze, Matthias W.; Allain, Frederic H. T.; Castello, Alfredo; Hennig, Janosch
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Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase
err2024-08-19
err0
errOAAI
errArragain, Benoit; Krischuns, Tim; Pelosse, Martin; Drncova, Petra; Blackledge, Martin; Naffakh, Nadia; Cusack, Stephen
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Structural snapshots of phenuivirus cap-snatching and transcription
err2024-05-06
err0
errOAAI
errWilliams, Harry M.; Thorkelsson, Sigurdur R.; Vogel, Dominik; Busch, Carola; Milewski, Morlin; Cusack, Stephen; Gruenewald, Kay; Quemin, Emmanuelle R. J.; Rosenthal, Maria
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The RBPome of influenza A virus NP-mRNA reveals a role for TDP-43 in viral replication
err2024-04-30
err1
errOAAI
errDupont, Maud; Krischuns, Tim; Gianetto, Quentin Giai; Paisant, Sylvain; Bonazza, Stefano; Brault, Jean-Baptiste; Douche, Thibaut; Arragain, Benoit; Florez-Prada, Alberto; Perez-Perri, Joel, I; Hentze, Matthias W.; Cusack, Stephen; Matondo, Mariette; Isel, Catherine; Courtney, David G.; Naffakh, Nadia
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The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome
err2024-02-05
err5
errOAAI
errKrischuns, Tim; Arragain, Benoit; Isel, Catherine; Paisant, Sylvain; Budt, Matthias; Wolff, Thorsten; Cusack, Stephen; Naffakh, Nadia
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Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex
err2024-01-01
err3
errOAAI
errDubiez, Etienne; Pellegrini, Erika; Brask, Maja Finderup; Garland, William; Foucher, Anne-Emmanuelle; Huard, Karine; Jensen, Torben Heick; Cusack, Stephen; Kadlec, Jan
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Multivalent Dynamic Colocalization of Avian Influenza Polymerase and Nucleoprotein by Intrinsically Disordered ANP32A Reveals the Molecular Basis of Human Adaptation
err2023-09-14
err4
errOAAI
errCamacho-Zarco, Aldo R.; Yu, Lefan; Krischuns, Tim; Dedeoglu, Selin; Maurin, Damien; Bouvignies, Guillaume; Crepin, Thibaut; Ruigrok, Rob W. H.; Cusack, Stephan; Naffakh, Nadia; Blackledge, Martin
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Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface
err2023-09-06
err4
errOAAI
errLethier, Mathilde; Huard, Karine; Hons, Michael; Favier, Adrien; Brutscher, Bernhard; Erba, Elisabetta Boeri; Abbott, Derek W.; Cusack, Stephen; Pellegrini, Erika
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Structural and functional characterization of the Sin Nombre virus L protein
err2023-08-07
err7
errOAAI
errMeier, Kristina; Thorkelsson, Sigurdur; Trouilleton, Quentin Durieux; Vogel, Dominik; Yu, Dingquan; Kosinski, Jan; Cusack, Stephen; Malet, Helene; Grunewald, Kay; Quemin, Emmanuelle R. J.; Rosenthal, Maria
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Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein
err2023-01-18
err12
errOAAI
errWilliams, Harry M.; Thorkelsson, Sigurdur R.; Vogel, Dominik; Milewski, Morlin; Busch, Carola; Cusack, Stephen; Gruenewald, Kay; Quemin, Emmanuelle R. J.; Rosenthal, Maria
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The mechanism of genome replication and transcription in bunyaviruses
err2023-01-12
err30
errOAAI
errMalet, Helene; Williams, Harry M.; Cusack, Stephen; Rosenthal, Maria
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Adenosine-Dependent Activation Mechanism of Prodrugs Targeting an Aminoacyl-tRNA Synthetase
err2023-01-04
err8
errOAAI
errHoffmann, Guillaume; Le Gorrec, Madalen; Mestdach, Emeline; Cusack, Stephen; Salmon, Loic; Jensen, Malene Ringkjobing; Palencia, Andres
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Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD (vol 18, e1010328, 2022)
err2023-01-04
err0
errOAAI
errKrischuns, Tim; Isel, Catherine; Drncova, Petra; Lukarska, Maria; Pflug, Alexander; Paisant, Sylvain; Navratil, Vincent; Cusack, Stephen; Naffakh, Nadia
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