Valerie M. Weaver - Publications, H-index & Citations

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Valerie M. Weaver

University of California

94H-index

441Paper Count

5.7WCitation Count

Published Papers 175

Publication Date

The microenvironment dictates glyco-immune surveillance via HSF1-mediated metabolism

Science Advances

IF12.5

2026-08-07

OAAI

Kevin M. Tharp; Sangwoo Park; Greg A. Timblin; Alicia L. Richards; Jordan A. Berg; Nicholas M. Twells; Nicholas M. Riley; Kyle Alvarez; Allen Lee; Egan L. Peltan; D. Judy Shon; Erica Stevenson; Kimberly Tsui; Francesco Palomba; Austin E. Y. T. Lefebvre; Ross W. Soens; Jaya L. Thangaraj; Nadia M.E. Ayad; Joseph A. Rhodenhiser; Johanna ten Hoeve; Kevin Healy; Michelle Digman; Andrew Dillin; Nevan J. Krogan; Carolyn R. Bertozzi; Dan S. Kaufman; Sanju Sinha; Danielle L. Swaney; Lara K. Mahal; Jason R. Cantor; Matthew J. Paszek; Valerie M. Weaver

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Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells

Developmental Cell

IF8.7

2026-07-13

OAAI

Nadia M.E. Ayad; Aisha Almsoud; Johnathon N. Lakins; Ajinkya Ghagre; Allen J. Ehrlicher; Ophir D. Klein; FuiBoon Kai; Valerie M. Weaver

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NCOR2 represses MHC class I molecule expression to drive metastatic progression of breast cancer

Nature Communications

IF15.7

2026-05-05

OAAI

Pavla Ticha; Jason J. Northey; Radhika Narain; Shivang Sharma; Johnathon N. Lakins; Hugo Gonzalez; Kelly Kersten; Alastair J. Ironside; Allison P. Drain; Martin Zidek; Kelvin K. Tsai; Yunn-Yi Chen; Eugene Shenderov; Valerie M. Weaver

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AXONAL INJURY IS A TARGETABLE DRIVER OF GLIOBLASTOMA PROGRESSION

NEURO-ONCOLOGY

IF13.4

2025-10-01

OAAI

Baronik, Z. Florjanic; Clements, M.; Tang, W.; Ragdale, H. Simpson; Fernandez, R. Oria; Volteras, D.; White, I. J.; Beattie, G.; Uddin, I; Lenn, T.; Lindsay, R.; Devesa, S. Castro; Karamched, S. R.; Lythgoe, M. F.; Shahrezaei, V; Weaver, V. M.; Marguerat, S.; Hill, C. S.; Parrinello, S.

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Resolving fibrosis by stimulating HSC-dependent extracellular matrix degradation

Science Translational Medicine

IF14.6

2025-08-27

PREAI

Sachin Sharma; Vijaya Prathigudupu; Carson Cable; Lia R. Serrano; Srilaxmi Nerella; Alina Chen; Ghmkin Hassan; Johnathon Lakins; Carlos Lizama Valenzuela; Tatsuya Tsukui; Roopa Ramamoorthi; Jae-Jun Kim; Holger Willenbring; Aras N. Mattis; Regan F. Volk; Balyn W. Zaro; Joshua J. Coon; Richard Beresis; William F. DeGrado; Valerie M. Weaver; Stephanie A. Christenson; Hyunil Jo; Jennifer Y. Chen

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Axonal injury is a targetable driver of glioblastoma progression

Nature

IF48.5

2025-08-20

OAAI

Melanie Clements; Wenhao Tang; Zan Florjanic Baronik; Holly Simpson Ragdale; Roger Oria; Dimitrios Volteras; Ian J. White; Gordon Beattie; Imran Uddin; Tchern Lenn; Rachel Lindsay; Sara Castro Devesa; Saketh R. Karamched; Mark F. Lythgoe; Vahid Shahrezaei; Valerie M. Weaver; Ryoichi Sugisawa; Federico Roncaroli; Samuel Marguerat; Ciaran S. Hill; Simona Parrinello

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Mechanical regulation of extracellular vesicle activity during tumour progression

Nature Biomedical Engineering

IF26.6

2025-08-06

PREAI

Kshitiz Parihar; Di-Ao Liu; Ghmkin Hassan; David A. Issadore; Paul A. Janmey; Valerie M. Weaver; Wei Guo; Ravi Radhakrishnan

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Tissue mechanics in tumor heterogeneity and aggression

Trends in Cancer

IF17.5

2025-04-29

OAAI

Anna-Marie Finger; Audrey Marie Hendley; Diego Figueroa; Hugo Gonzalez; Valerie Marie Weaver

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Tension-induced organelle stress: an emerging target in fibrosis

TRENDS IN PHARMACOLOGICAL SCIENCES

IF19.9

2025-02-01

PREAI

Kai, Fuiboon; Leidal, Andrew M.; Weaver, Valerie M.

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Differential stiffness between brain vasculature and parenchyma promotes metastatic infiltration through vessel co-option

NATURE CELL BIOLOGY

IF19.1

2024-10-24

PREAI

Uroz, Marina; Stoddard, Amy E.; Sutherland, Bryan P.; Courbot, Olivia; Oria, Roger; Li, Linqing; Ravasio, Cara R.; Ngo, Mai T.; Yang, Jinling; Tefft, Juliann B.; Eyckmans, Jeroen; Han, Xue; Elosegui-Artola, Alberto; Weaver, Valerie M.; Chen, Christopher S.

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nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer

CANCER RESEARCH

IF16.6

2024-09-15

PREAI

Hendley, Audrey M.; Ashe, Sudipta; Urano, Atsushi; Ng, Martin; Phu, Tuan A.; Peng, Xianlu Laura; Luan, Changfei; Finger, Anna-Marie; Jang, Gun Ho; Kerper, Natanya R.; Berrios, David I.; Jin, David; Lee, Jonghyun; Riahi, Irene R.; Gbenedio, Oghenekevwe M.; Chung, Christina; Roose, Jeroen P.; Yeh, Jen Jen; Gallinger, Steven; Biankin, Andrew V.; O'Kane, Grainne M.; Ntranos, Vasilis; Chang, David K.; Dawson, David W.; Kim, Grace E.; Weaver, Valerie M.; Raffai, Robert L.; Hebrok, Matthias

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Tumor-associated macrophages restrict CD8+ T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment

NATURE CANCER

IF28.5

2024-06-03

PREAI

Tharp, Kevin M.; Kersten, Kelly; Maller, Ori; Timblin, Greg A.; Stashko, Connor; Canale, Fernando P.; Menjivar, Rosa E.; Hayward, Mary-Kate; Berestjuk, Ilona; ten Hoeve, Johanna; Samad, Bushra; Ironside, Alastrair J.; di Magliano, Marina Pasca; Muir, Alexander; Geiger, Roger; Combes, Alexis J.; Weaver, Valerie M.

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Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx- mediated resistance to HER2targeting therapies

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-05-06

OAAI

Goyette, Marie-Anne; Stevens, Laura E.; Depinho, Carolyn R.; Seehawer, Marco; Nishida, Jun; Li, Zheqi; Wilde, Callahan M.; Li, Rong; Qiu, Xintao; Pyke, Alanna L.; Zhao, Stephanie; Lim, Klothilda; Tender, Gabrielle S.; Northey, Jason J.; Riley, Nicholas M.; Long, Henry W.; Bertozzi, Carolyn R.; Weaver, Valerie M.; Polyak, Kornelia

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RETRACTION: Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin (Retraction of Vol 33, Pg 2441, 2014)

ONCOGENE

IF7.3

2024-02-23

OAAI

Damiano, L.; Stewart, K. M.; Cohet, N.; Mouw, J. K.; Lakins, J. N.; Debnath, J.; Reisman, D.; Nickerson, J. A.; Imbalzano, A. N.; Weaver, V. M.

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Stiff matrix induces exosome secretion to promote tumour growth (vol 25, pg 415, 2023)

NATURE CELL BIOLOGY

IF19.1

2024-02-12

OAAI

Wu, Bin; Liu, Di-Ao; Guan, Lei; Myint, Phyoe Kyawe; Chin, Likang; Dang, Hien; Xu, Ye; Ren, Jinqi; Li, Ting; Yu, Ziyan; Jabban, Sophie; Mills, Gordon B.; Nukpezah, Jonathan; Chen, Youhai H.; Furth, Emma E.; Gimotty, Phyllis A.; Wells, Rebecca G.; Weaver, Valerie M.; Radhakrishnan, Ravi; Wang, Xin Wei; Guo, Wei

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nSMase2-generated ceramide promotes PDA aggression through exosome reprogramming of the stroma

CANCER RESEARCH

IF16.6

2024-01-16

PREAI

Hendley, Audrey M.; Urano, Atsushi; Peng, Xianlu L.; Ashe, Sudipta; Phu, Tuan A.; Ng, Martin; Kerper, Natanya R.; Berrios, David I.; Lee, Jonghyun; Jin, David; Jang, Gun H.; Gbenedio, Oghenekevwe M.; Roose, Jeroen P.; Yeh, Jen J.; Gallinger, Steven; Biankin, Andrew V.; Ntranos, Vasilis; Chang, David K.; Dawson, David W.; Kim, Grace E.; Weaver, Valerie M.; Raffai, Robert L.; Hebrok, Matthias

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Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk

CELL STEM CELL

IF20.4

2024-01-01

OAAI

Northey, Jason J.; Hayward, Mary-Kate; Yui, Yoshihiro; Stashko, Connor; Kai, Fuiboon; Mouw, Janna K.; Thakar, Dhruv; Lakins, Jonathon N.; Ironside, Alastair J.; Samson, Susan; Mukhtar, Rita A.; Hwang, E. Shelley; Weaver, Valerie M.

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Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression (vol 22, pg 497, 2016)

NATURE MEDICINE

IF50

2023-11-28

OAAI

Laklai, Hanane; Miroshnikova, Yekaterina A.; Pickup, Michael W.; Collisson, Eric A.; Kim, Grace E.; Barrett, Alex S.; Hill, Ryan C.; Lakins, Johnathon N.; Schlaepfer, David D.; Mouw, Janna K.; Lebleu, Valerie S.; Roy, Nilotpal; Novitskiy, Sergey V.; Johansen, Julia S.; Poli, Valeria; Kalluri, Raghu; Iacobuzio-Donahue, Christine A.; Wood, Laura D.; Hebrok, Matthias; Hansen, Kirk; Moses, Harold L.; Weaver, Valerie M.

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α6β4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-κB-dependent resistance to apoptosis in 3D mammary acini (Expression of Concern of Vol 120, Pg 3700, 2007)

JOURNAL OF CELL SCIENCE

IF3.6

2023-10-19

OAAI

Friedland, Julie C.; Lakins, Johnathon N.; Kazanietz, Marcelo G.; Chernoff, Jonathan; Boettiger, David; Weaver, Valerie M.

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Design of a mucin-selective protease for targeted degradation of cancer-associated mucins

NATURE BIOTECHNOLOGY

IF41.7

2023-08-03

OAAI

Pedram, Kayvon; Shon, D. Judy; Tender, Gabrielle S.; Mantuano, Natalia R.; Northey, Jason J.; Metcalf, Kevin J.; Wisnovsky, Simon P.; Riley, Nicholas M.; Forcina, Giovanni C.; Malaker, Stacy A.; Kuo, Angel; George, Benson M.; Miller, Caitlyn L.; Casey, Kerriann M.; Vilches-Moure, Jose G.; Ferracane, Michael J.; Weaver, Valerie M.; Laeubli, Heinz; Bertozzi, Carolyn R.

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Research Directions