Not logged in Single-cell analysis of breast cancer metastasis reveals epithelial-mesenchymal plasticity signatures associated with poor outcomes Winkler, Juliane; Tan, Weilun; Diadhiou, Catherine M. M.; Mcginnis, Christopher S.; Abbasi, Aamna; Hasnain, Saad; Durney, Sophia; Atamaniuc, Elena; Superville, Daphne; Awni, Leena; Lee, Joyce V.; Hinrichs, Johanna H.; Wagner, Patrick S.; Singh, Namrata; Hein, Marco Y.; Borja, Michael; Detweiler, Angela M.; Liu, Su-Yang; Nanjaraj, Ankitha; Sitarama, Vaishnavi; Rugo, Hope S.; Neff, Norma; Gartner, Zev J.; Pisco, Angela Oliveira; Goga, Andrei; Darmanis, Spyros; Werb, Zena Share Save
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Ets2-dependent stromal regulation of mouse mammary tumors Man, AK; Young, LJT; Tynan, JA; Lesperance, J; Egeblad, M; Werb, Z; Hauser, CA; Muller, WJ; Cardiff, RD; Oshima, RG Share Save
Cell archetypes in human brain metastases: Connecting programs in tumor cells with the microenvironment Gonzalez, Hugo; Mei, Wenbin; Robles, Isabella; Hagerling, Catharina; Allen, Breanna; Okholm, Trine Hauge; Nanjaraj, Ankitha; Verbeek, Tamara; Kalavacherla, Sandhya; Van Gogh, Merel; Georgiou, Stephen; Daras, Mariza; Phillips, Joanna J.; Spitzer, Matthew H.; Roose, Jeroen P.; Werb, Zena Share Save
Bisphenol A replacement chemicals, BPF and BPS, induce protumorigenic changes in human mammary gland organoid morphology and proteome Winkler, Juliane; Liu, Pengyuan; Phong, Kiet; Hinrichs, Johanna H.; Ataii, Nassim; Williams, Katherine; Hadler-Olsen, Elin; Samson, Susan; Gartner, Zev J.; Fisher, Susan; Werb, Zena Share Save
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Synthetic Tuning of Domain Stoichiometry in Nanobody-Enzyme Megamolecules Metcalf, Kevin J.; Kimmel, Blaise R.; Sykora, Daniel J.; Modica, Justin A.; Parker, Kelly A.; Berens, Eric; Dai, Raymond; Dravid, Vinayak P.; Werb, Zena; Mrksich, Milan Share Save
Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression Maller, Ori; Drain, Allison P.; Barrett, Alexander S.; Borgquist, Signe; Ruffell, Brian; Zakharevich, Igor; Pham, Thanh T.; Gruosso, Tina; Kuasne, Hellen; Lakins, Johnathon N.; Acerbi, Irene; Barnes, J. Matthew; Nemkov, Travis; Chauhan, Aastha; Gruenberg, Jessica; Nasir, Aqsa; Bjarnadottir, Olof; Werb, Zena; Kabos, Peter; Chen, Yunn-Yi; Hwang, E. Shelley; Park, Morag; Coussens, Lisa M.; Nelson, Andrew C.; Hansen, Kirk C.; Weaver, Valerie M. Share Save
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LGR5 in breast cancer and ductal carcinoma in situ: a diagnostic and prognostic biomarker and a therapeutic target Hagerling, Catharina; Owyong, Mark; Sitarama, Vaishnavi; Wang, Chih-Yang; Lin, Charlene; van den Bijgaart, Renske J. E.; Koopman, Charlotte D.; Brenot, Audrey; Nanjaraj, Ankitha; Warnberg, Fredrik; Jirstrom, Karin; Klein, Ophir D.; Werb, Zena; Plaks, Vicki Share Save
Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing Davis, Ryan T.; Blake, Kerrigan; Ma, Dennis; Gabra, Mari B. Ishak; Hernandez, Grace A.; Phung, Anh T.; Yang, Ying; Maurer, Dustin; Lefebvre, Austin E. Y. T.; Alshetaiwi, Hamad; Xiao, Zhengtao; Liu, Juan; Locasale, Jason W.; Digman, Michelle A.; Mjolsness, Eric; Kong, Mei; Werb, Zena; Lawson, Devon A. Share Save
Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression Marsh, Timothy; Kenific, Candia M.; Suresh, Deepthisri; Gonzalez, Hugo; Shamir, Eliah R.; Mei, Wenbin; Tankka, Alexandra; Leidal, Andrew M.; Kalavacherla, Sandhya; Woo, Kimberly; Werb, Zena; Debnath, Jayanta Share Save
A framework for advancing our understanding of cancer-associated fibroblasts Sahai, Erik; Astsaturov, Igor; Cukierman, Edna; DeNardo, David G.; Egeblad, Mikala; Evans, Ronald M.; Fearon, Douglas; Greten, Florian R.; Hingorani, Sunil R.; Hunter, Tony; Hynes, Richard O.; Jain, Rakesh K.; Janowitz, Tobias; Jorgensen, Claus; Kimmelman, Alec C.; Kolonin, Mikhail G.; Maki, Robert G.; Powers, R. Scott; Pure, Ellen; Ramirez, Daniel C.; Scherz-Shouval, Ruth; Sherman, Mara H.; Stewart, Sheila; Tlsty, Thea D.; Tuveson, David A.; Watt, Fiona M.; Weaver, Valerie; Weeraratna, Ashani T.; Werb, Zena Share Save
MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy Owyong, Mark; Chou, Jonathan; van den Bijgaart, Renske J. E.; Kong, Niwen; Efe, Gizem; Maynard, Carrie; Talmi-Frank, Dalit; Solomonov, Inna; Koopman, Charlotte; Hadler-Olsen, Elin; Headley, Mark; Lin, Charlene; Wang, Chih-Yang; Sagi, Irit; Werb, Zena; Plaks, Vicki Share Save
Immune effector monocyte-neutrophil cooperation induced by the primary tumor prevents metastatic progression of breast cancer Hagerling, Catharina; Gonzalez, Hugo; Salari, Kiarash; Wang, Chih-Yang; Lin, Charlene; Robles, Isabella; van Gogh, Merel; Dejmek, Annika; Jirstrom, Karin; Werb, Zena Share Save
MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indices McGinnistm, Christopher S.; Patterson, David M.; Winkler, Juliane; Conrad, Daniel N.; Hein, Marco Y.; Srivastava, Vasudha; Hu, Jennifer L.; Murrow, Lyndsay M.; Weissman, Jonathan S.; Werb, Zena; Chow, Eric D.; Gartner, Zev J. Share Save
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Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive, basal-like breast cancer Drain, Allison P.; Takai, Ken; Lawson, Devon A.; Littlepage, Laurie E.; Karpuj, Marcela; Kessenbrock, Kai; Le, Annie; Inoue, Kenichi; Weaver, Valerie M.; Werb, Zena Share Save
Tumor cell-adipocyte gap junctions activate lipolysis in breast cancer Camarda, Roman; Williams, Jeremy; Malkov, Serghei; Zimmerman, Lisa J.; Manning, Suzanne; Aran, Dvir; Beardsley, Andrew; Van de Mark, Daniel; van Haren, Jeffrey; Chen, Yong; Berdan, Charles; Louie, Sharon; Mahieu, Celine; Winkler, Juliane; Willey, Elizabeth; Gagnon, John D.; Shinoda, Kosaku; Ansel, K. Mark; Werb, Zena; Nomura, Daniel C.; Kajimura, Shingo; Wittmann, Torsten; Butte, Atul J.; Sanders, Melinda E.; Liebler, Daniel C.; Krings, Gregor; Shepherd, John A.; Goga, Andrei Share Save
Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity Nguyen, Quy H.; Pervolarakis, Nicholas; Blake, Kerrigan; Ma, Dennis; Davis, Ryan Tevia; James, Nathan; Phung, Anh T.; Willey, Elizabeth; Kumar, Raj; Jabart, Eric; Driver, Ian; Rock, Jason; Goga, Andrei; Khan, Seema A.; Lawson, Devon A.; Werb, Zena; Kessenbrock, Kai Share Save
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