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Combination of ALK2 and cholesterol targeting agents exploits linked genetic and metabolic dependencies in diffuse midline glioma Rogers, Rebecca; Grabovska, Yura; Mackay, Alan; Carvalho, Diana; Dobinson, Claire; Pereira, Rita; Burford, Anna; Bevington, Laura; Molinari, Valeria; Song, Jiin; Tari, Haider; Ruddle, Ruth; Nkrumah, Josephine; Sejdiu, Drenusha; Chew, Nicole; Tsui, Vanessa; Sun, Claire; Khan, Aaminah; Pericoli, Giulia; Vinci, Mara; Fortin, Jerome; Sampson, Peter; Tsoli, Maria; Zeigler, David; Firestein, Ron; Jones, Chris Share Save
Multidimensional, integrative profiling identifies BCL2L1 methylation as a predictor of MCL1 dependency in pediatric malignancies Adjumain, Shazia; Daniel, Paul; Sun, Claire Xin; Bradshaw, Gabrielle; Chew, Nicole J.; Tsui, Vanessa; Lee, Hanbyeol; Loi, Melissa; Zhukova, Nataliya; Habarakada, Dilru; Yoel, Abigail; Vaghjiani, Vijesh G.; Game, Shaye; Ludlow, Louise E.; Neeman, Naama; Sweet-Cordero, E. Alejandro; Eisenstat, David D.; Cain, Jason E.; Firestein, Ron Share Save
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MULTI-DIMENSIONAL INTEGRATIVE PROFILING IDENTIFIES BCL2L1 METHYLATION AS A PREDICTIVE BIOMARKER FOR MCL-1 ACTIVITY IN PEDIATRIC HIGH-GRADE GLIOMAS Adjumain, Shazia; Sun, Claire Xin; Bradshaw, Gabrielle; Chew, Nicole; Tsui, Vanessa; Lee, Hanbyeol; Loi, Melissa; Zhukova, Nataliya; Habarakada, Dilru; Ludlow, Louise; Neeman, Naama; Daniel, Paul; Firestein, Ron Share Save
A NOVEL ROLE FOR ACVR1/ALK2 IN REGULATING CHOLESTEROL BIOSYNTHESIS PROVIDES A NEW COMBINATORIAL THERAPEUTIC APPROACH FOR PATIENTS WITH DMG Rogers, Rebecca; Grabovaska, Yura; Mackay, Alan; Carvalho, Diana; Dobinson, Claire; Pereira, Rita; Sejdiu, Drenusha; Burford, Anna; Molinari, Valeria; Ruddle, Ruth; Raynaud, Florence; Chew, Nicole; Tsui, Vanessa; Sun, Claire; Firestein, Ron; Jones, Chris Share Save
Fancm has dual roles in the limiting of meiotic crossovers and germ cell maintenance in mammals Tsui, Vanessa; Lyu, Ruqian; Novakovic, Stevan; Stringer, Jessica M.; Dunleavy, Jessica E. M.; Granger, Elissah; Semple, Tim; Leichter, Anna; Martelotto, Luciano G.; Merriner, D. Jo; Liu, Ruijie; McNeill, Lucy; Zerafa, Nadeen; Hoffmann, Eva R.; O'Bryan, Moira K.; Hutt, Karla; Deans, Andrew J.; Heierhorst, Jorg; McCarthy, Davis J.; Crismani, Wayne Share Save
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