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Ammar Al‐Chalabi

king's college london

101H-index
639Paper Count
5.8WCitation Count
Published Papers 240
Publication Date
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Strenuous physical activity is associated with a younger age of amyotrophic lateral sclerosis onset in two independent cohorts
errBrain Communications
IF4.5
err2026-07-13
err0
errOAAI
errJaimee Kennedy; Ahmad Al Khleifat; Andrew King; Safa Al-Sarraj; Ammar Al-Chalabi; Jacqueline C Mitchell; Claire Troakes
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Large-scale exome analyses reveal new rare variant contributions in amyotrophic lateral sclerosis
errNature Genetics
IF29
err2026-03-31
err0
errOAAI
errPaul J. Hop; Maarten Kooyman; Brendan J. Kenna; Ramona A. J. Zwamborn; Kristel R. van Eijk; Yan Wang; Charlotte H. van Dijk; Erwin Bekema; Wouter van Rheenen; Paul Beele; Joke J. F. A. van Vugt; Ahmad Al Khleifat; Alfredo Iacoangeli; Johnathan Cooper-Knock; Bradley N. Smith; Simon Topp; Anneke J. van der Kooi; Vera Fominykh; Vivian Drory; Yossef Lerner; Yehuda Shovman; Dominic B. Rowe; Kelly L. Williams; Russell L. McLaughlin; Jessica Hurt; Yunfeng Huang; Chia-Yen Chen; Ellen Tsai; Heiko Runz; Eleonora Aronica; Ewout J. N. Groen; Michael A. van Es; R. Jeroen Pasterkamp; Sali M. K. Farhan; Fleur C. Garton; Allan F. McRae; Pamela A. McCombe; Robert D. Henderson; Dongsheng Fan; Lenka Šlachtová; Helle Høyer; Agnes L. Nishimura; Ruben J. Cauchi; Lev Brylev; Boris Rogelj; Blaž Koritnik; Janez Zidar; Teresa Salas; Jesus S. Mora Pardina; Marc Gotkine; Monica Povedano; Philippe Corcia; Patrick Vourc’h; Philippe Couratier; Markus Weber; Matthew C. Kiernan; Roger Pamphlett; Ian P. Blair; Mamede de Carvalho; Nazli A. Başak; Caroline Ingre; Peter M. Andersen; Lorne Zinman; Ekaterina Rogaeva; Ian R. MacKenzie; Nicolas Dupre; Guy A. Rouleau; Bryan J. Traynor; Nicola Ticozzi; Adriano Chiò; Vincenzo Silani; Orla Hardiman; Hemali Phatnani; Matthew B. Harms; Clifton L. Dalgard; Jonathan D. Glass; John E. Landers; Philip Van Damme; Karen E. Morrison; Pamela J. Shaw; Chris E. Shaw; Ammar Al-Chalabi; Leonard H. van den Berg; Kevin P. Kenna; Jan H. Veldink
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errSave
The ethics of self-experimentation: what is the right thing to do? Self-designed gene therapy
errBRAIN
IF11.7
err2025-10-01
err0
PREAI
errCox, Vivienne; Cochrane, Thomas; Al-Chalabi, Ammar
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Landscapes of missense variant impact for human superoxide dismutase 1
erramerican journal of human genetics
IF0
err2025-09-15
err0
errOAAI
errAnna Axakova; Megan Ding; Atina G. Cote; Radha Subramaniam; Vignesh Senguttuvan; Haotian Zhang; Jochen Weile; Samuel V. Douville; Marinella Gebbia; Ammar Al-Chalabi; Alexander Wahl; Jason Reuter; Jessica Hurt; Adele A. Mitchell; Stephanie Fradette; Peter M. Andersen; Warren van Loggerenberg; Frederick P. Roth
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The use of genetic testing in amyotrophic lateral sclerosis (ALS): a practical approach
errAmyotrophic Lateral Sclerosis and Frontotemporal Degeneration
IF2.8
err2025-08-08
err0
errOAAI
errAmina Chaouch; Ashley Crook; Andrew G. L. Douglas; Christopher J McDermott; Ammar Al-Chalabi; Alisdair McNeill; Jennifer Bedford; Jade Howard; Rhona MacLeod
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Amyotrophic Lateral Sclerosis as a Multistep Process in the United States: A Population-Based Study
errAnnals of Clinical and Translational Neurology
IF3.9
err2025-07-22
err0
errOAAI
errJasmine Berry; Jaime Raymond; Theodore Larson; D. Kevin Horton; Moon Han; Theresa Nair; Ammar Al-Chalabi; Paul Mehta
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errSave
Neuropsychological assessment practices in PRECISION-ALS: challenges and opportunities for harmonization
errAmyotrophic Lateral Sclerosis and Frontotemporal Degeneration
IF2.8
err2025-07-21
err0
errOAAI
errEmmet Costello; Joke De Vocht; Emily Beswick; Éanna Mac Domhnaill; Colm Peelo; Juliette Foucher; Emily J. Mayberry; Theresa Chiwera; Fenna Hiemstra; Alejandro Caravaca Puchades; Barbara Iazzolino; Francesca Palumbo; Inês Alves; Elisabeth Kasper; Miriam Galvin; Mark Heverin; Caroline Ingre; Christopher J. Mcdermott; Pamela Shaw; Ammar Al-Chalabi; Leonard H. Van Den Berg; Mónica Povedano Panadés; Adriano Chiò; Mamede De Carvalho; Sofiane Bencheikh; Philippe Corcia; Mohammed Mouzouri; Andreas Hermann; Sharon Abrahams; Niall Pender; Philip Van Damme; Orla Hardiman
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Patient reported outcome measures require scale metrification and quantified precision: evidence from the assessment of breathlessness in people with ALS/MND
errAmyotrophic Lateral Sclerosis and Frontotemporal Degeneration
IF2.8
err2025-07-20
err0
errOAAI
errCarolyn A. Young; Amina Chaouch; Christopher J. Mcdermott; Ammar Al-Chalabi; Suresh Kumar Chhetri; Nicola Waters; Richard Buccleuch; Roger J. Mills; Alan Tennant
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Hospitalizations as an outcome measure in COURAGE-ALS
errAmyotrophic Lateral Sclerosis and Frontotemporal Degeneration
IF2.8
err2025-06-12
err0
errOAAI
errStacy A. Rudnicki; Ammar Al-Chalabi; Jinsy A. Andrews; Adriano Chio; Philippe Corcia; Philippe Couratier; Merit E. Cudkowicz; Mamede De Carvalho; Angela Genge; Orla Hardiman; Terry Heiman-Patterson; Robert D. Henderson; Caroline Ingre; Wendy Johnston; Albert Ludolph; Nicholas J. Maragakis; Timothy M. Miller; Jesus S. Mora; Susanne Petri; Zachary Simmons; Leonard H. Van Den Berg; Lorne Zinman; Katherine E. Herder; Stuart Kupfer; Fady I. Malik; Lisa Meng; Tyrell J. Simkins; Jenny Wei; Andrew A. Wolff; Jeremy M. Shefner
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Investigating the Performance of Oxford Nanopore Long-Read Sequencing with Respect to Illumina Microarrays and Short-Read Sequencing
errINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
err2025-05-08
err0
errOAAI
errSantos, Renato; Lee, Hyunah; Williams, Alexander; Baffour-Kyei, Anastasia; Lee, Sang-Hyuck; Troakes, Claire; Al-Chalabi, Ammar; Breen, Gerome; Iacoangeli, Alfredo
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Respiratory function, survival, and NIV prevalence over time in ALS - a PRECISION ALS study
errAMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION
IF2.8
err2025-05-06
err0
errOAAI
errSennfalt, Stefan; Al-Chalabi, Ammar; Caravaca Puchades, Alejandro; Chio, Adriano; Corcia, Philippe; Galvin, Miriam; Hardiman, Orla; Heverin, Mark; Hobin, Frederik; Holmdahl, Oskar; Lamaire, Nikita; Mac Domhnaill, Eanna; McDonough, Harry; Manera, Umberto; McDermott, Christopher J.; McFarlane, Robert; Mouzouri, Mouhammed; Ombelet, Fouke; Opie-Martin, Sarah; Panades, Monica Povedano; Shaw, Pamela; Terrafeta Pastor, Cristina; Van Damme, Philipe; Van Den Berg, Leonard; Van Eijk, Ruben P. A.; Vasta, Rosario; Veldink, Jan H.; Weemering, Daphne N.; Ingre, Caroline
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Examining changing working status and caregiver assistance in amyotrophic lateral sclerosis (ALS) using large-scale European databases as part of PRECISION-ALS
errAMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION
IF2.8
err2025-05-06
err0
errOAAI
errMcdonough, Harry; Mcfarlane, Robert; Puchades, Alejandro Caravaca; Chio, Adriano; Corcia, Philippe; Galvin, Miriam; Heverin, Mark; Hobin, Frederik; Holmdahl, Oskar; Ingre, Caroline; Lamaire, Nikita; Domhnaill, Eanna Mac; Manera, Umberto; Mouzouri, Mohammed; Ombelet, Fouke; Opie-Martin, Sarah; Panades, Monica Povedano; Sennfalt, Stefan; Pastor, Cristina Terrafeta; Veldink, Jan H.; van Damme, Philip; van den Berg, Leonard; van Eijk, Ruben P. A.; Vasta, Rosario; Weemering, Daphne N.; Al-Chalabi, Ammar; Shaw, Pamela; McDermott, Christopher J.; Hardiman, Orla
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Mapping the natural history of amyotrophic lateral sclerosis: time-to-event analysis of clinical milestones in the pan-European, population-based PRECISION-ALS cohort
errAMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION
IF2.8
err2025-05-06
err0
errOAAI
errCaravaca Puchades, Alejandro; McDonough, Harry E.; Al-Chalabi, Ammar; Chio, Adriano; Corcia, Philippe; Galvin, Miriam; Hardiman, Orla; Heverin, Mark; Hobin, Frederik; Holmdahl, Oskar; Ingre, Caroline; Lamaire, Nikita; Mac Domhnaill, Eanna; Manera, Umberto; Mcfarlane, Robert; Mouzouri, Mohammed; Ombelet, Fouke; Opie-Martin, Sarah; Sennfaelt, Stefan; Terrafeta Pastor, Cristina; Veldink, Jan H.; Van Damme, Philip; van den Berg, Leonard; van Eijk, Ruben P. A.; Vasta, Rosario; Weemering, Daphne N.; Shaw, Pamela; McDermott, Christopher J.; Povedano Panades, Monica
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errSave
Real-world prognostic role of riluzole use in ALS: a multi-center study from PRECISION-ALS
errAMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION
IF2.8
err2025-05-06
err0
errOAAI
errVasta, Rosario; Ombelet, Fouke; Hobin, Frederik; Manera, Umberto; Ammar, Al-Chalabi; Caravaca Puchades, Alejandro; Corcia, Philippe; Galvin, Miriam; Hardiman, Orla; Heverin, Mark; Holmdahl, Oskar; Ingre, Caroline; Lamaire, Nikita; Mcdermott, Christopher; Mac Domhnaill, Eanna; Mcdonough, Harry; Mcfarlane, Robert; Mouzouri, Mohammed; Sarah, Opie-Martin; Povedano Panades, Monica; Sennfalt, Stefan; Shaw, Pamela; Terrafeta Pastor, Cristina; van den Berg, Leonard H.; van Eijk, Ruben P. A.; Veldink, Jan H.; Weemering, Daphne N.; Van Damme, Philip; Chio, Adriano
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Reldesemtiv in Amyotrophic Lateral Sclerosis: Results From the COURAGE-ALS Randomized Clinical Trial
errJAMA NEUROLOGY
IF21.3
err2025-05-01
err0
PREAI
errShefner, Jeremy M.; Cudkowicz, Merit E.; Genge, Angela; Hardiman, Orla; Al-Chalabi, Ammar; Andrews, Jinsy A.; Chio, Adriano; Corcia, Philippe; Couratier, Philippe; de Carvalho, Mamede; Heiman-Patterson, Terry; Henderson, Robert D.; Ingre, Caroline; Johnston, Wendy; Ludolph, Albert; Maragakis, Nicholas J.; Miller, Timothy M.; Mora, Jesus S.; Petri, Susanne; Simmons, Zachary; van den Berg, Leonard H.; Zinman, Lorne; Kupfer, Stuart; Malik, Fady I.; Meng, Lisa; Simkins, Tyrell J.; Wei, Jenny; Wolff, Andrew A.; Rudnicki, Stacy A.; COURAGE ALS Study Grp
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Respiratory measurements, respiratory symptoms, and quality of life in ALS: results from the REVEALS study
errAMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION
IF2.8
err2025-03-06
err0
errOAAI
errDeirdre Murray; James Rooney; Dara Meldrum; Ammar Al-Chalabi; Tommy M. Bunte; Theresa Chiwera; Mutahhara Choudhury; Adriano Chio; Lauren Fenton; Jennifer Fortune; Lindsay Maidment; Umberto Manera; Christopher J. McDermott; Myrte Meyjes; Rachel Tattersall; Maria Claudia Torrieri; Philip Van Damme; Elien Vanderlinden; Claire Wood; Leonard H. Van Den Berg; Orla Hardiman
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Persistent high levels of perceived fatigue are not associated with hypermetabolism in patients with amyotrophic lateral sclerosis
errAMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION
IF2.8
err2025-03-01
err0
errOAAI
errLauren E. Buckett; Cory J. Holdom; Stephanie L. Howe; Pamela A. McCombe; Robert D. Henderson; Ammar Al-Chalabi; Frederik J. Steyn; Shyuan T. Ngo
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Oligogenic structure of amyotrophic lateral sclerosis has genetic testing, counselling and therapeutic implications
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2025-02-13
err0
errOAAI
errIacoangeli, Alfredo; Dilliott, Allison A.; Al Khleifat, Ahmad; Andersen, Peter M.; Basak, Nazli A.; Cooper-Knock, Johnathan; Corcia, Philippe; Couratier, Philippe; Decarvalho, Mamede; Drory, Vivian E.; Glass, Jonathan D.; Gotkine, Marc; Lerner, Yosef M.; Hardiman, Orla; Landers, John E.; Mclaughlin, Russell L.; Pardina, Jesus S. Mora; Morrison, Karen; Pinto, Susana; Povedano, Monica; Shaw, Christopher E.; Shaw, Pamela J.; Silani, Vincenzo; Ticozzi, Nicola; van Damme, Philip; van den Berg, Leonard H.; Vourc'h, Patrick; Weber, Markus; Veldink, Jan Herman; Dobson, Richard; Rouleau, Guy A.; Al-Chalabi, Ammar; Farhan, Sali M. K.
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An open-label Phase 2a study to assess the safety and tolerability of trimetazidine in patients with amyotrophic lateral sclerosis
errBRAIN COMMUNICATIONS
IF4.5
err2025-02-08
err0
errOAAI
errvan Eijk, Ruben P. A.; Steyn, Frederik J.; van Mantgem, Mark R. Janse; Schmidt, Angela; Meyjes, Myrte; Allen, Sally; Daygon, Dara, V; Loeffler, Jean-Philippe; Al-Chalabi, Ammar; van den Berg, Leonard H.; Henderson, Robert D.; Ngo, Shyuan T.
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Brain distribution study of [14C]-Riluzole following intranasal administration in mice
errINTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
err2025-02-01
err0
errOAAI
errBaker, Rafal S.; Wang, Julie Tzu-Wen; Rouatbi, Nadia; Lu, Yuan; Al-adhami, Taha; Asker, Daniel; Rahman, Khondaker Miraz; Al-Chalabi, Ammar; Forbes, Ben; Bansal, Sukhi; Al-Jamal, Khuloud T.
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Research Directions

No research directions
Co-authors
Cooperation Journals
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