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S

Simone de Brot

University of Bern

19H-index
180Paper Count
1.7KCitation Count
Published Papers 33
Publication Date
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Western diet-induced MASH in PWK/PhJ mice identifies disruptions in amino acid and sphingolipid metabolism contributing to cardiac dysfunction
errNature Communications
IF15.7
err2026-05-20
err0
errOAAI
errSandra Rodríguez-López; Miguel Pérez-Rodríguez; Alaa Badreddine; Rafael Calais Gaspar; Henrique J. Novaes Morgan; Ikki Sakuma; Giacomo V. G. von Alvensleben; Alejandro Alonso-Calleja; Stacia P. A. Everts; Nicolas-Enzo Suter; Giorgia Benegiamo; Christine Goepfert; Simone de Brot; José Manuel Villalba; Gerald I. Shulman; Kristina Schoonjans; Johan Auwerx
errShare
errSave
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
errMolecular Oncology
IF4.5
err2026-03-01
err0
errOAAI
errJeyapalan, Jennie N.; Metzler, Veronika M.; de Brot, Simone; Woodcock, Corinne L.; Harris, Anna E.; Lothion-Roy, Jennifer; Nilsson, Emeli M.; Ntekim, Atara; Toss, Michael S.; Persson, Jenny L.; Khani, Francesca; Robinson, Brian D.; Gudas, Lorraine J.; Rakha, Emad; Heery, David M.; Rutland, Catrin S.; Mongan, Nigel P.
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Identification and Characterisation of Canine Osteosarcoma Biomarkers and Therapeutic Targets
errCancers
IF4.4
err2026-01-15
err0
errOAAI
errJorja Jackson-Oxley; Aziza A. Alibhai; Rachel Thompson; Jennifer Lothion-Roy; Simone de Brot; Mark D. Dunning; Jennie N. Jeyapalan; Nigel P. Mongan; Catrin S. Rutland
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errSave
Wesselsbron Virus-Induced Hepatitis in Ewes and Lambs Unraveled Through Machine Learning-Driven Digital Histopathology
errTransboundary and Emerging Diseases
IF3
err2026-01-01
err0
errOAAI
errGrau-Roma, Llorenc; de Brot, Simone; Zimoch, Marta; Clerc, Loane; Donze, Noelle; Liniger, Matthias; Brito, Francisco; Herrera, Adrian; Godel, Aurelie; Summerfield, Artur; Benarafa, Charaf; Garcia-Nicolas, Obdulio
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DAXX and ATRX Expression in Canine Prostate and Bladder Cancer Identified by Immunohistochemistry-A Digital Quantitative Pilot Study
errVeterinary Sciences
IF2.3
err2025-12-17
err0
errOAAI
errSpitzer, Annika; Aupperle-Lellbach, Heike; Spitzer, Martin; Weidle, Silvia; Aeschlimann, Leonore; Schwinn, Joshua; Klopfleisch, Robert; de Brot, Simone
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errSave
Comparative Digital Estrogen Receptor Alpha (ERα) Expression Analysis in Benign and Malignant Prostate Tissue of Men and Dogs
errPROSTATE
IF2.5
err2025-12-01
err0
errOAAI
errLothion-Roy, Jennifer; Aeschlimann, Leonore; Hiller, Lea Anna; Rottenberg, Sven; Mongan, Nigel P.; Rutland, Catrin S.; Rakha, Emad; Dean, Alexander; Rubin, Mark A.; de Brot, Simone
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errSave
Artificial intelligence predicts c-KIT exon 11 genotype by phenotype in canine cutaneous mast cell tumors: Can human observers learn it?
errVETERINARY PATHOLOGY
IF1.7
err2025-10-01
err0
PREAI
errPuget, Chloe; Ganz, Jonathan; Bertram, Christof A.; Conrad, Thomas; Baeblich, Malte; Voss, Anne; Landmann, Katharina; Haake, Alexander F. H.; Spree, Andreas; Hartung, Svenja; Aeschlimann, Leonore; Soto, Sara; de Brot, Simone; Dettwiler, Martina; Aupperle-Lellbach, Heike; Bolfa, Pompei; Bartel, Alexander; Kiupel, Matti; Breininger, Katharina; Aubreville, Marc; Klopfleisch, Robert
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errSave
The functional and therapeutic potential of epitranscriptomics in breast cancer
errEpigenomics
IF2.6
err2025-08-18
err0
PREAI
errRachel L. Thompson; Jennifer Lothion-Roy; Eleanor Bellows; Corinne L. Woodcock; Jorja Jackson-Oxley; Maria Haque; Dhruvika Varun; Amber A. Kumari; Mansour Alsaleem; Simone de Brot; Atara Ntekim; Musalwa Muyangwa-Semanova; Emad Rakha; Srinivasan Madhusudan; Nathan Archer; Rupert G. Fray; Sheeba Irshad; Richard D. Emes; Jennie N. Jeyapalan; Catrin S. Rutland; Nigel P. Mongan; Anna E. Harris
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errSave
Reducing Driveline Infection Risk in durable Mechanical Circulatory Systems with Ultra-Flexible Wires for Energy Transfer
errheart and lung transplantation
IF0
err2025-07-24
err0
errOAAI
errAndreas P. Kourouklis; Xi Wu; Julius Kaemmel; Sanne Hertegonne; Srikanth Mairpady Shambat; Mihyun Lee; Christian Grossmann; Raphael Hagen; Daniel Fehr; Fabrizio Spano; Carolina Pietsch; Simone de Brot; Nikola Cesarovic; Qun Ren; Mathias Bonmarin; Miriam Weisskopf; Annelies S. Zinkernagel; Evgenij Potapov; Volkmar Falk; Edoardo Mazza
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errSave
Cigarette smoke-induced disordered microbiota aggravates the severity of influenza A virus infection
errMSYSTEMS
IF4.6
err2024-12-17
err0
errOAAI
errWuthrich, Tsering; de Brot, Simone; Richina, Veronica; Mostacci, Nadja; Baumann, Zora; Leborgne, Nathan G. F.; Godel, Aurelie; Alves, Marco P.; Bentires-Alj, Mohamed; Benarafa, Charaf; Hilty, Markus
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errSave
CRIPTO's multifaceted role in driving aggressive prostate cancer unveiled by in vivo, organoid, and patient data
errONCOGENE
IF7.3
err2024-11-26
err0
errOAAI
errRodrigues Sousa, Elisa; de Brot, Simone; Zoni, Eugenio; Zeinali, Soheila; Brunello, Andrea; Scarpa, Mario; De Menna, Marta; La Manna, Federico; Abey Alexander, Allen; Klima, Irena; Freeman, David W.; Gates, Brooke L.; Cristaldi, Domenico A.; Guenat, Olivier T.; Kruithof, Boudewijn P. T.; Spike, Benjamin T.; Chouvardas, Panagiotis; Kruithof-de Julio, Marianna
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errSave
Pathological Characteristics of Muscle Rejection and Dysfunction in a Swine Vascularized Composite Allotransplantation Model and a Scoring Proposal: A Pilot Study
errTRANSPLANTATION
IF5
err2024-10-23
err0
errOAAI
errZhang, Lei; He, Chang; Arenas Hoyos, Isabel; Banz, Yara; Zubler, Cedric; Hirsiger, Stefanie; Lese, Ioana; Constantinescu, Mihai; Rieben, Robert; de Brot, Simone; Olariu, Radu
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errSave
Loss of PI5P4Kα Slows the Progression of a Pten Mutant Basal Cell Model of Prostate Cancer
errMOLECULAR CANCER RESEARCH
IF4.7
err2024-10-09
err0
errOAAI
errTriscott, Joanna; Lehner, Marika; Benjak, Andrej; Reist, Matthias; Emerling, Brooke M.; Ng, Charlotte K. Y.; de Brot, Simone; Rubin, Mark A.
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errSave
Epitranscriptomic mechanisms of androgen signalling and prostate cancer
errNEOPLASIA
IF7.7
err2024-10-01
err1
errOAAI
errPatke, Rodhan; Harris, Anna E.; Woodcock, Corinne L.; Thompson, Rachel; Santos, Rute; Kumari, Amber; Allegrucci, Cinzia; Archer, Nathan; Gudas, Lorraine J.; Robinson, Brian D.; Persson, Jenny L.; Fray, Rupert; Jeyapalan, Jennie; Rutland, Catrin S.; Rakha, Emad; Madhusudan, Srinivasan; Emes, Richard D.; Muyangwa-Semenova, Musalwa; Alsaleem, Mansour; de Brot, Simone; Green, William; Ratan, Hari; Mongan, Nigel P.; Lothion-Roy, Jennifer
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errSave
Disruption of HSD17B12 in mouse hepatocytes leads to reduced body weight and defect in the lipid droplet expansion associated with microvesicular steatosis
errFASEB JOURNAL
IF4.2
err2024-09-09
err0
errOAAI
errHeikela, Hanna; Mairinoja, Laura; Ruohonen, Suvi T.; Rytkonen, Kalle T.; de Brot, Simone; Laiho, Asta; Koskinen, Satu; Suomi, Tomi; Elo, Laura L.; Strauss, Leena; Poutanen, Matti
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errSave
Protein Aggregation on Metal Oxides Governs Catalytic Activity and Cellular Uptake
errSMALL
IF12.1
err2024-03-31
err0
errOAAI
errNissler, Robert; Dennebouy, Lena; Gogos, Alexander; Gerken, Lukas R. H.; Dommke, Maximilian; Zimmermann, Monika; Pais, Michael A.; Neuer, Anna L.; Matter, Martin T.; Kissling, Vera M.; de Brot, Simone; Lese, Ioana; Herrmann, Inge K.
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errSave
Intranodal Injection of Immune Activator Demonstrates Antitumor Efficacy in an Adjuvant Approach
errVACCINES
IF3.4
err2024-03-26
err0
errOAAI
errJosi, Romano; Ogrina, Anete; Rothen, Dominik; Balke, Ina; Casaramona, Arnau Sole; de Brot, Simone; Mohsen, Mona O.
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errSave
Transdermal wires for improved integration in vivo
errBIOMATERIALS ADVANCES
IF6
err2023-10-01
err0
errOAAI
errKourouklis, Andreas P.; Kaemmel, Julius; Wu, Xi; Banos, Miguel; Chanfon, Astrid; de Brot, Simone; Ferrari, Aldo; Cesarovic, Nikola; Falk, Volkmar; Mazza, Edoardo
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errSave
Inhibition of nonsense-mediated mRNA decay reduces the tumorigenicity of human fibrosarcoma cells
errNAR CANCER
IF3.2
err2023-09-06
err5
errOAAI
errNasif, Sofia; Colombo, Martino; Uldry, Anne-Christine; Schroder, Markus S.; de Brot, Simone; Muhlemann, Oliver
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errSave
Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer
errGENOME BIOLOGY
IF9.4
err2023-08-28
err5
errOAAI
errWong, Kim; Abascal, Federico; Ludwig, Latasha; Aupperle-Lellbach, Heike; Grassinger, Julia; Wright, Colin W.; Allison, Simon J.; Pinder, Emma; Phillips, Roger M.; Romero, Laura P.; Gal, Arnon; Roady, Patrick J.; Pires, Isabel; Guscetti, Franco; Munday, John S.; Peleteiro, Maria C.; Pinto, Carlos A.; Carvalho, Tania; Cota, Joao; Du Plessis, Elizabeth C.; Constantino-Casas, Fernando; Plog, Stephanie; Moe, Lars; de Brot, Simone; Bemelmans, Ingrid; Amorim, Renee Laufer; Georgy, Smitha R.; Prada, Justina; del Pozo, Jorge; Heimann, Marianne; Nunes, Louisiane de Carvalho; Simola, Outi; Pazzi, Paolo; Steyl, Johan; Ubukata, Rodrigo; Vajdovich, Peter; Priestnall, Simon L.; Suarez-Bonnet, Alejandro; Roperto, Franco; Millanta, Francesca; Palmieri, Chiara; Ortiz, Ana L.; Barros, Claudio S. L.; Gava, Aldo; Soderstrom, Minna E.; O'Donnell, Marie; Klopfleisch, Robert; Manrique-Rincon, Andrea; Martincorena, Inigo; Ferreira, Ingrid; Arends, Mark J.; Wood, Geoffrey A.; Adams, David J.; van der Weyden, Louise
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Research Directions

No research directions
Co-authors
Cooperation Journals
L
Lewis C. Cantley
H-index: 214 · Papers: 1.4K
M
Mark A. Rubin
H-index: 186 · Papers: 1.5K
J
Johan Auwerx
H-index: 183 · Papers: 913
G
Gerald I. Shulman
H-index: 183 · Papers: 819
V
Volkmar Falk
H-index: 124 · Papers: 1.6K
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