Not logged in Phase 1b/2 study of orally administered pexidartinib in combination with radiation therapy and temozolomide in patients with newly diagnosed glioblastoma Mendez, Joe S.; Cohen, Adam L.; Eckenstein, Midori; Jensen, Randy L.; Burt, Lindsay M.; Salzman, Karen L.; Chamberlain, Marc; Hsu, Henry H.; Hutchinson, Marguerite; Iwamoto, Fabio; Ligon, Keith L.; Mrugala, Maciej M.; Pelayo, Michael; Plotkin, Scott R.; Puduvalli, Vinay K.; Raizer, Jeffrey; Reardon, David A.; Sterba, Michael; Walbert, Tobias; West, Brian L.; Wong, Eric T.; Zhang, Chao; Colman, Howard Share Save
Mutations in the conserved C-terminal sequence in thyroid hormone receptor dissociate hormone-dependent activation from interference with AP-1 activity Saatcioglu, F; Lopez, G; West, BL; Zandi, E; Feng, WJ; Lu, HP; Esmaili, A; Apriletti, JW; Kushner, PJ; Baxter, JD; Karin, M Share Save
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Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions Csaszar, Eszter; Lenart, Nikolett; Cserep, Csaba; Koernyei, Zsuzsanna; Fekete, Rebeka; Posfai, Balazs; Balazsfi, Diana; Hangya, Balazs; Schwarcz, Anett D.; Szabadits, Eszter; Szoellosi, David; Szigeti, Krisztian; Mathe, Domokos; West, Brian L.; Sviatko, Katalin; Bras, Ana Rita; Mariani, Jean-Charles; Kliewer, Andrea; Lenkei, Zsolt; Hricisak, Laszlo; Benyo, Zoltan; Baranyi, Maria; Sperlagh, Beata; Menyhart, Akos; Farkas, Eszter; Denes, Adam Share Save
Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma Sathyasaikumar, Korrapati V.; Perez de la Cruz, Veronica; Pineda, Benjamin; Vazquez Cervantes, Gustavo Ignacio; Ramirez Ortega, Daniela; Donley, David W.; Severson, Paul L.; West, Brian L.; Giorgini, Flaviano; Fox, Jonathan H.; Schwarcz, Robert Share Save
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Mitigation of helium irradiation-induced brain injury by microglia depletion Allen, Barrett D.; Syage, Amber; Maroso, Mattia; Baddour, Al Anoud D.; Luong, Valerie; Minasyan, Harutyun; Giedzinski, Erich; West, Brian L.; Soltesz, Ivan; Limoli, Charles L.; Baulch, Janet E.; Acharya, Munjal M. Share Save
A phase 1/2 study of the oral FLT3 inhibitor pexidartinib in relapsed/refractory FLT3-ITD-mutant acute myeloid leukemia Smith, Catherine C.; Levis, Mark J.; Frankfurt, Olga; Pagel, John M.; Roboz, Gail J.; Stone, Richard M.; Wang, Eunice S.; Severson, Paul L.; West, Brian L.; Le, Mai H.; Kayser, Sabine; Lam, Bao; Hsu, Henry H.; Zhang, Chao; Bollag, Gideon; Perl, Alexander E. Share Save
Attenuation of neuroinflammation reverses Adriamycin-induced cognitive impairments Allen, Barrett D.; Apodaca, Lauren A.; Syage, Amber R.; Markarian, Mineh; Baddour, Al Anoud D.; Minasyan, Harutyun; Alikhani, Leila; Lu, Celine; West, Brian L.; Giedzinski, Erich; Baulch, Janet E.; Acharya, Munjal M. Share Save
Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model Spangenberg, Elizabeth; Severson, Paul L.; Hohsfield, Lindsay A.; Crapser, Joshua; Zhang, Jiazhong; Burton, Elizabeth A.; Zhang, Ying; Spevak, Wayne; Line, Jack; Phan, Nicole Y.; Habets, Gaston; Rymar, Andrey; Tsang, Garson; Walters, Jason; Nespi, Marika; Singh, Parmveer; Broome, Stephanie; Ibrahim, Prabha; Zhang, Chao; Bollag, Gideon; West, Brian L.; Green, Kim N. Share Save
Phase Ib study of the combination of pexidartinib (PLX3397), a CSF-1R inhibitor, and paclitaxel in patients with advanced solid tumors Wesolowski, Robert; Sharma, Neelesh; Reebel, Laura; Rodal, Mary Beth; Peck, Alexandra; West, Brian L.; Marimuthu, Adhirai; Severson, Paul; Karlin, David A.; Dowlati, Afshin; Le, Mai H.; Coussens, Lisa M.; Rugo, Hope S. Share Save
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Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice Elmore, Monica R. P.; Hohsfield, Lindsay A.; Kramar, Eniko A.; Soreq, Lilach; Lee, Rafael J.; Pham, Stephanie T.; Najafi, Allison R.; Spangenberg, Elizabeth E.; Wood, Marcelo A.; West, Brian L.; Green, Kim N. Share Save
The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanoma Giricz, Orsi; Mo, Yongkai; Dahlman, Kimberly B.; Cotto-Rios, Xiomaris M.; Vardabasso, Chiara; Hoa Nguyen; Matusow, Bernice; Bartenstein, Matthias; Polishchuk, Veronika; Johnson, Douglas B.; Bhagat, Tushar D.; Shellooe, Rafe; Burton, Elizabeth; Tsai, James; Zhang, Chao; Habets, Gaston; Greally, John M.; Yu, Yiting; Kenny, Paraic A.; Fields, Gregg B.; Pradhan, Kith; Stanley, E. Richard; Bernstein, Emily; Bollag, Gideon; Gavathiotis, Evripidis; West, Brian L.; Sosman, Jeffrey A.; Verma, Amit K. Share Save
Microglia control the spread of neurotropic virus infection via P2Y12 signalling and recruit monocytes through P2Y12-independent mechanisms Fekete, Rebeka; Cserep, Csaba; Lenart, Nikolett; Toth, Krisztina; Orsolits, Barbara; Martinecz, Bernadett; Mehes, Elod; Szabo, Balint; Nemeth, Valeria; Gonci, Balazs; Sperlagh, Beata; Boldogkoi, Zsolt; Kittel, Agnes; Baranyi, Maria; Ferenczi, Szilamer; Kovacs, Krisztina; Szalay, Gergely; Rozsa, Balazs; Webb, Connor; Kovacs, Gabor G.; Hortobagyi, Tibor; West, Brian L.; Kornyei, Zsuzsanna; Denes, Adam Share Save
Microglia ablation alleviates myelin-associated catatonic signs in mice Janova, Hana; Arinrad, Sahab; Balmuth, Evan; Mitjans, Marina; Hertel, Johannes; Habes, Mohamad; Bittner, Robert A.; Pan, Hong; Goebbels, Sandra; Begemann, Martin; Gerwig, Ulrike C.; Langner, Soenke; Werner, Hauke B.; Kittel-Schneider, Sarah; Homuth, Georg; Davatzikos, Christos; Voelzke, Henry; West, Brian L.; Reif, Andreas; Grabe, Hans Joergen; Boretius, Susann; Ehrenreich, Hannelore; Nave, Klaus-Armin Share Save
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