Joseph Schlessinger - Publications, H-index & Citations

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Joseph Schlessinger

Yale University

174H-index

719Paper Count

12.4WCitation Count

Published Papers 147

Publication Date

Exposing the obscured influence of state-controlled media via causal inference of quotation propagation

SCIENTIFIC REPORTS

IF3.9

2025-01-07

OAAI

Schlessinger, Joseph; Bennet, Richard; Coakwell, Jacob; Smith, Steven; Kao, Edward

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Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-04-16

PREAI

Bellone, Stefania; Jeong, Kyungjo; Halle, Mari Kylleso; Krakstad, Camilla; Mcnamara, Blair; Greenman, Michelle; Mutlu, Levent; Demirkiran, Cem; Hartwich, Tobias Max Philipp; Yang-Hartwich, Yang; Zipponi, Margherita; Buza, Natalia; Hui, Pei; Raspagliesi, Francesco; Lopez, Salvatore; Paolini, Biagio; Milione, Massimo; Perrone, Emanuele; Scambia, Giovanni; Altwerger, Gary; Ravaggi, Antonella; Bignotti, Eliana; Huang, Gloria S.; Andikyan, Vaagn; Clark, Mitchell; Ratner, Elena; Azodi, Masoud; Schwartz, Peter E.; Quick, Charles M.; Angioli, Roberto; Terranova, Corrado; Zaidi, Samir; Nandi, Shuvro; Alexandrov, Ludmil B.; Siegel, Eric R.; Choi, Jungmin; Schlessinger, Joseph; Santin, Alessandro D.

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Phosphatidylinositol 3-kinase mediates epidermal growth factor-induced activation of the c-Jun N-terminal kinase signaling pathway

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

127

OAAI

Logan, SK; Falasca, M; Hu, P; Schlessinger, J

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A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

359

OAAI

Rodrigues, GA; Falasca, M; Zhang, ZT; Ong, SH; Schlessinger, J

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Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

125

OAAI

Melillo, RM; Santoro, M; Ong, SH; Billaud, M; Fusco, A; Hadari, YR; Schlessinger, J; Lax, I

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FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

338

OAAI

Ong, SH; Guy, GR; Hadari, YR; Laks, S; Gotoh, N; Schlessinger, J; Lax, I

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Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

338

OAAI

Hadari, YR; Kouhara, H; Lax, I; Schlessinger, J

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No obvious abnormality in mice deficient in receptor protein tyrosine phosphatase β

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

104

OAAI

Harroch, S; Palmeri, M; Rosenbluth, J; Custer, A; Okigaki, M; Shrager, P; Blum, M; Buxbaum, JD; Schlessinger, J

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Lacrimo-auricuto-dento-digital syndrome is caused by reduced activity of the fibroblast growth factor 10 (FGF10)-FGF receptor 2 signaling pathwayv

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Shams, Imad; Rohmann, Edyta; Eswarakumar, Veraragavan P.; Lew, Erin D.; Yuzawa, Satoru; Wollnik, Bernd; Schlessinger, Joseph; Lax, Irit

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The docking protein FRS2α is an essential component of multiple fibroblast growth factor responses during early mouse development

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Gotoh, N; Manova, K; Tanaka, S; Murohashi, M; Hadari, Y; Lee, A; Hamada, Y; Hiroe, T; Ito, M; Kurihara, T; Nakazato, H; Shibuya, M; Lax, I; Lacy, E; Schlessinger, J

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Receptor protein tyrosine phosphatase γ is a marker for pyramidal cells and sensory neurons in the nervous system and is not necessary for normal development

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Lamprianou, Smaragda; Vacaresse, Nathalie; Suzuki, Yoshihisa; Meziane, Hamid; Buxbaum, Joseph D.; Schlessinger, Joseph; Harroch, Sheila

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Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

298

OAAI

Dawson, JP; Berger, MB; Lin, CC; Schlessinger, J; Lemmon, MA; Ferguson, KM

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The docking protein Gab1 is an essential component of an indirect mechanism for fibroblast growth factor stimulation of the phosphatidylinositol 3-kinase/Akt antiapoptotic pathway

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Lamothe, B; Yamada, M; Schaeper, U; Birchmeier, W; Lax, I; Schlessinger, J

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Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-03-21

OAAI

Krimmer, Stefan G.; Bertoletti, Nicole; Suzuki, Yoshihisa; Katic, Luka; Mohanty, Jyotidarsini; Shu, Sheng; Lee, Sangwon; Lax, Irit; Mi, Wei; Schlessinger, Joseph

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Heparin is essential for optimal cell signaling by FGF21 and for regulation of βKlotho cellular stability

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-02-06

OAAI

An, Seong J.; Mohanty, Jyotidarsini; Tome, Francisco; Suzuki, Yoshihisa; Lax, Irit; Schlessinger, Joseph

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Unveiling molecular insights into the mechanism of activation of oncogenic phosphoinositide 3-kinase mutants

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-12-07

OAAI

Krimmer, Stefan G.; Schlessinger, Joseph

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Regulation of EGF-stimulated activation of the PI-3K/AKT pathway by exocyst-mediated exocytosis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-11-23

OAAI

An, Seong J.; Anneken, Alexander; Xi, Zhiqun; Choi, Changseon; Schlessinger, Joseph; Toomre, Derek

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Covalent Modification of the JH2 Domain of Janus Kinase 2

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2022-10-24

OAAI

Henry, Sean P.; Liosi, Maria-Elena; Ippolito, Joseph A.; Menges, Fabian; Newton, Ana S.; Schlessinger, Joseph; Jorgensen, William L.

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Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein

CELL REPORTS

IF6.9

2022-10-01

OAAI

Park, Joon Sung; Choi, Jungyuen; Cao, Longxing; Mohanty, Jyotidarsini; Suzuki, Yoshihisa; Park, Andy; Baker, David; Schlessinger, Joseph; Lee, Sangwon

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Insights on JAK2 Modulation by Potent, Selective, and Cell-Permeable Pseudokinase-Domain Ligands

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-06-02

OAAI

Liosi, Maria-Elena; Ippolito, Joseph A.; Henry, Sean P.; Krimmer, Stefan G.; Newton, Ana S.; Cutrona, Kara J.; Olivarez, Rene A.; Mohanty, Jyotidarsini; Schlessinger, Joseph; Jorgensen, William L.

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Research Directions