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Shyh‐Dar Li

University of British Columbia

43H-index
121Paper Count
8.8KCitation Count
Published Papers 65
Publication Date
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Next-generation colon-targeted oral delivery for immune modulation in inflammatory bowel diseases
errJournal of Controlled Release
IF11.5
err2026-07-30
err0
errOAAI
errShang-Wen Lin; Letong Wang; Po-Han Chao; Po-Yu Chou; Shyh-Dar Li
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Temporal Immune and Metabolic Shifts Drive the Anti-Tumor Efficacy of Resiquimod-Loaded Nanoparticles in Peritoneal Carcinomatosis
errAdvanced Healthcare Materials
IF9.6
err2026-07-28
err0
errOAAI
errVanessa Chan; Po-Han Chao; XuXin Sun; Jun Han; Sarah MacPherson; Lucas J. Andrew; Noah Y. Brittain; Tien Do; Marcel B. Bally; Julian J. Lum; Shyh-Dar Li
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Incorporation of a polyamine into lipid nanoparticles increases the endosomal release and transfection of nucleic acids without toxicity
errJournal of Controlled Release
IF11.5
err2025-10-28
err0
PREAI
errRamya Kannan; Binh Tran; Quan Le; Lukas Hohenwarter; Po-Han Chao; Vivekjot Brar; Sophie Roesger; Steven Chen; Feng Zhao; Jiamin Wu; Angel Lee; Jing-Ping Liou; Shyh-Dar Li
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errSave
Emerging vesicular nanosystems capable of effectively targeting hepatocytes
errNanomedicine
IF3.9
err2025-07-21
err0
PREAI
errVanessa Chan; April St Pierre; Tien Do; Shyh-Dar Li
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errSave
Biodegradable polymers with tertiary amines enhance mRNA delivery of lipid nanoparticles via improved endosomal escape
errBiomaterials
IF12.9
err2025-07-08
err0
PREAI
errFeng Zhao; Bruno Luppi; Po-Han Chao; Jinfan Yang; Ying Zhang; Ran Feng; Vanessa Chan; Ramya Kannan; Songtao Dong; Athan Gogoulis; Leo Wang; Angel Lee; Zachary Hudson; Shyh-Dar Li
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errSave
Imiquimod-Loaded Phospholipid-Free Small Unilamellar Vesicles Activate the Tumor Immune Microenvironment to Treat Liver Cancer and Liver Metastases
errAdvanced Healthcare Materials
IF9.6
err2025-06-17
err0
errOAAI
errVanessa Chan; Hsin-Mei Lee; Haruka Takata; Sheng-Liang Cheng; Yu-Ting Yen; Lisa Pfeifer; Luke Rushton; Po-Han Chao; Feng Zhao; Chun Yat Ong; Nojoud Al-Fayez; Tatsuhiro Ishida; Yunching Chen; Shyh-Dar Li
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errSave
Nanomedicines modulate the tumor immune microenvironment for cancer therapy
errEXPERT OPINION ON DRUG DELIVERY
IF5.4
err2024-10-04
err1
PREAI
errChao, Po-Han; Chan, Vanessa; Li, Shyh-Dar
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Intranasal delivery of low-dose anti-CD124 antibody enhances treatment of chronic rhinosinusitis with nasal polyps
errBIOMATERIALS
IF12.9
err2024-07-01
err1
PREAI
errWu, Jiamin; Jones, Natalie; Chao, Po-Han; Chan, Vanessa; Hohenwarter, Lukas; Wu, Angeline; Bergamo, Marta; Rodriguez-Rodriguez, Cristina; Saatchi, Katayoun; Liang, Alex; Haefei, Urs O.; Tan, Zheng; Hedtrich, Sarah; Andrew, Lucas J.; Li, Shyh-Dar
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errSave
Liposome biodistribution mapping with in vivo X-ray fluorescence imaging
errNANOSCALE
IF5.1
err2024-01-01
err1
errOAAI
errSaladino, Giovanni Marco; Chao, Po-Han; Brodin, Bertha; Li, Shyh-Dar; Hertz, Hans Martin
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errSave
Modification and Delivery of Enkephalins for Pain Modulation
errINTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
err2023-11-01
err3
PREAI
errHohenwarter, Lukas; Bottger, Roland; Li, Shyh-Dar
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errSave
Protamine-mediated efficient transcellular and transmucosal delivery of proteins
errJOURNAL OF CONTROLLED RELEASE
IF11.5
err2023-04-01
err10
PREAI
errWu, Jiamin; Jones, Natalie; Fayez, Nojoud A. L.; Chao, Po-Han; Wu, Angeline; de Araujo, Daniele Ribeiro; Rouhollahi, Elham; Jia, Analisa; Li, Shyh-Dar
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In Vitro Properties and Pharmacokinetics of Temporarily PEGylated Onc72 Prodrugs
errADVANCED HEALTHCARE MATERIALS
IF9.6
err2023-01-20
err6
errOAAI
errMohammed, Gubran Khalil; Bottger, Roland; Krizsan, Andor; Volke, Daniela; Moetzing, Marina; Li, Shyh-Dar; Knappe, Daniel; Hoffmann, Ralf
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errSave
Bioinspired Nanocomplexes Comprising Phenolic Acid Derivative and Human Serum Albumin for Cancer Therapy
errNANO LETTERS
IF9.1
err2022-12-15
err10
PREAI
errWang, Zhaomeng; Liu, Yanhua; Li, Shuo; Meng, Fanlin; Yu, Jiang; Zhou, Shuang; Dong, Songtao; Ye, Jianying; Li, Lingxiao; Zhang, Chuang; Qiu, Shengnan; Lin, Guimei; Liu, Hongzhuo; Li, Shyh-Dar; He, Zhonggui; Wang, Yongjun
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errSave
The mechanism of Hepatocyte-Targeting and safety profile of Phospholipid-Free small unilamellar vesicles
errINTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
err2022-11-01
err0
PREAI
errFayez, Nojoud A. L.; Bottger, Roland; Brown, Jennifer; Rouhollahi, Elham; Li, Shyh-Dar
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errSave
Chemically engineering the drug release rate of a PEG-paclitaxel conjugate using click and steric hindrance chemistries for optimal efficacy
errBIOMATERIALS
IF12.9
err2022-10-01
err5
PREAI
errNguyen, Anne; Chao, Po-Han; Ong, Chun Yat; Rouhollahi, Elham; AL Fayez, Nojoud; Lin, Louis; Brown, Jennifer I.; Bottger, Roland; Page, Brent; Wong, Harvey; Li, Shyh-Dar
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errSave
Hepatocyte-targeted delivery of imiquimod reduces hepatitis B virus surface antigen
errJOURNAL OF CONTROLLED RELEASE
IF11.5
err2022-10-01
err6
PREAI
errAl Fayez, Nojoud; Rouhollahi, Elham; Ong, Chun Yat; Wu, Jiamin; Nguyen, Anne; Bottger, Roland; Cullis, Pieter R.; Witzigmann, Dominik; Li, Shyh-Dar
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errSave
Development of a child-friendly oral drug formulation using liposomal multilamellar vesicle technology
errINTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
err2022-09-01
err3
PREAI
errAl Fayez, Nojoud; Bottger, Roland; Ghosh, Sreemoyee; Nakajima, Yushi; Chao, Po-Han; Rouhollahi, Elham; Nguyen, Anne; Cullis, Pieter R.; Witzigmann, Dominik; Li, Shyh-Dar
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Breaking the niche: multidimensional nanotherapeutics for tumor microenvironment modulation
errDRUG DELIVERY AND TRANSLATIONAL RESEARCH
IF5.5
err2022-06-13
err6
PREAI
errSwetha, K. Laxmi; Maravajjala, Kavya Sree; Li, Shyh-Dar; Singh, Manu Smriti; Roy, Aniruddha
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errSave
Interplay between the linker and polymer molecular weight of a self-assembling prodrug on the pharmacokinetics and therapeutic efficacy
errBIOMATERIALS SCIENCE
IF5.7
err2022-01-01
err5
PREAI
errNguyen, Anne; Rouhollahi, Elham; Bottger, Roland; Ong, Chun Yat; Chao, Po-Han; Wu, Jiamin; Chen, Yao; Li, Shyh-Dar
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errSave
Liposomal Resiquimod for Enhanced Immunotherapy of Peritoneal Metastases of Colorectal Cancer
errPHARMACEUTICS
IF5.5
err2021-10-15
err15
errOAAI
errPauli, Griffin; Chao, Po-Han; Qin, Zhu; Bottger, Roland; Lee, Suen Ern; Li, Shyh-Dar
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
L
Leaf Huang
H-index: 130 · Papers: 735
I
Ian F. Tannock
H-index: 111 · Papers: 616
P
Pieter R. Cullis
H-index: 108 · Papers: 478
D
David W. Hedley
H-index: 88 · Papers: 539
李
李硕 (Shuo Li)
H-index: 84 · Papers: 2.4K
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