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Neil L. Kelleher

northwestern university
H-index:106
Citation Count:4.4万
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Top-Down Proteomics in the Assessment of Kidney Donor Quality: a proof-of-concept for increased organ utilization

自上而下蛋白质组学在评估肾脏供体质量中的应用：提高器官利用率的概念验证

MOLECULAR & CELLULAR PROTEOMICS
IF5.5
2026-09-190
OAAI
Claudia Ctortecka; Dinesh Jaishankar; Pei Su; Che-Fan Huang; Indira Pla; Nathaniel Henning; Michael A.R. Hollas; Michelle A. Callegari; Meredith E. Taylor; Yu Min Lee; Amna Daud; David F. Pinelli; Vinayak Rohan; Michael A. Caldwell; Eleonora Forte; Aniel Sanchez; Neil L. Kelleher; Satish N. Nadig
Proteoform Detection Across 17,000 Single Nuclei From Differentiating Skin Keratinocytes

来自分化皮肤角蛋白细胞的17,000个单核中的蛋白型检测

MOLECULAR & CELLULAR PROTEOMICS
IF5.5
2026-08-010
OA
Kanchustambham, Vijaya Lakshmi; Pla, Indira; Xu, Tian; Su, Pei; Fisher, Nickolas P.; Hollas, Michael A. R.; Markiv, Paulina; Agarwal, Uday; Lysakowska, Monika; Kafader, Jared O.; Bao, Xiaomin; Kelleher, Neil L.
Mechanism-Based Inactivation of Human Ornithine Aminotransferase by Ethynyl- and Nitrile-Substituted Cyclopentene Analogues of γ-Aminobutyric Acids

基于机制的乙炔基和腈基取代的环戊烯γ-氨基丁酸类似物对人类鸟氨酸氨基转移酶的抑制

Journal of the American Chemical Society
IF15.6
2026-07-100
PRE
Feng Wang; Mary C. Corrigan; Nhat Hoang Van Le; Dorothy Duan; Corine O. Smith; Graham R. Moran; Neil L. Kelleher; Dali Liu; Richard B. Silverman
Structural Basis for the Pro-amyloidogenic Action and Ligand Binding of a Novel W72R Variant of Human Apolipoprotein A-I

人载脂蛋白A-I的一种新型W72R变异体的促淀粉样变性作用和配体结合的结构基础

Journal of Molecular Biology
IF4.5
2026-06-240
PRE
Tatiana Prokaeva; Shobini Jayaraman; Elena S. Klimtchuk; Caryn Libbey; Lisa Mendelson; Brian Spencer; Hui Chen; Nhat Hoang Van Le; Aniel Sanchez; Neil L. Kelleher; Surendra Dasari; Ellen D. McPhail; Lucas Pereira; Uri Avissar; Sandra Cerda; Sherry Wong; Francesca Lavatelli; Vaishali Sanchorawala; Olga Gursky
Characterizing Antibody-Drug Conjugates with High Molecular Heterogeneity by Native Direct Mass Technology

通过原位直接质谱技术表征高分子异质性抗体药物偶联物

Analytical Chemistry
IF6.7
2026-06-020
PRE
Phillip Y. Chu; Keely E. Fuller; Summer Baker Dockrey; Isabel Wang; Cheng-Wei Lin; Lizzie P. Harmon; Daojing Wang; Philip D. Compton; Jared O. Kafader; Neil L. Kelleher; Thomas H. Pillow; Jonathan L. Josephs; John C. Tran; Rachel Liuqing Shi
Probing Proteoform Heterogeneity from Single Human Oocytes

探究单个人类卵母细胞中的蛋白质异质性

MOLECULAR & CELLULAR PROTEOMICS
IF5.5
2026-04-090
OAAI
Nickolas P. Fisher; Vijaya Lakshmi Kanchustambham; Elizabeth L. Tsui; Chelsea Lock; Tian Xu; Hannah B. McDowell; Indira Pla; Diane C. Saunders; Jared O. Kafader; Monica M. Laronda; Neil L. Kelleher
Targeting Conformational Flexibility of a Reactive Intermediate to Enhance Selectivity of a GABA Aminotransferase Inactivator

靶向反应中间体的构象柔性以增强GABA转氨酶失活剂的专一性

Journal of the American Chemical Society
IF15.6
2026-02-190
PRE
Koon Mook Kang; Abigail L. Vargas; Luana Assis Ferreira; Benjamin James Des Soye; Mary Corrigan; Cathy Kexin Zhang; Feng Wang; Dorothy Duan; Neil L. Kelleher; Andrea G. Hohmann; Dali Liu; Richard B. Silverman
Direct Readout of Multivalent Chromatin Reader-Nucleosome Interactions by Nucleosome Mass Spectrometry
ACS Central Science
IF10.4
2026-02-050
OA
Alexander S. Lee; Nickolas P. Fisher; Matthew R. Marunde; Pei Su; Laiba F. Khan; Ryan J. Ezell; Zachary B. Gillespie; Bria Graham; Hailey F. Taylor; Ugochi C. Onuoha; Taojunfeng Su; Kevin Jooß; Luis F. Schachner; Harrison A. Fuchs; Kelsey Noll; Matthew J. Meiners; Marcus A. Cheek; Jonathan M. Burg; Zu-Wen Sun; Catherine A. Musselman; Michael-Christopher Keogh; Neil L. Kelleher
Proteoform medicine: characterizing and targeting protein forms in human disease

Proteofform医学: 表征并靶向人类疾病中的蛋白质形式

Nature Reviews Genetics
IF52
2026-01-050
PRE
Jennifer A. Korchak; S. Stephen Yi; Neil L. Kelleher; Nidhi Sahni; Gloria M. Sheynkman
Intact Proteoform Analysis by Capillary Electrophoresis-Mass Spectrometry. Are We There Yet?
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
2025-12-011
OAAI
Gould, Noah; Wang, Qianjie; Agar, Jeffrey N.; Brodbelt, Jennifer S.; Chen, Daoyang; Cupp-sutton, Kellye A.; Dominguez-vega, Elena; Fang, Fei; Fillet, Marianne; Fischer, Matthew S.; Gaspar, Attila; Ge, Ying; Gou, Marie-Jia; Gregus, Michal; Gstottner, Christoph; Hamidli, Narmin; Helms, Amanda; Hossain, Md Amin; Juetten, Kyle J.; Kelleher, Neil L.; Kraus, Tobias; Larson, Eli J.; Mellors, J. Scott; Nagy, Cynthia; Neususs, Christian; Redman, Erin A.; Schairer, Jasmin; Wu, Si; Xu, Tian; Zhao, Zhitao; Zhu, Guijie; Ivanov, Alexander R.; Jooss, Kevin; Sun, Liangliang
Automated Enzymatic Deglycosylation of Monoclonal Antibody with the SampleStream Platform

使用SampleStream平台对单克隆抗体进行自动化酶法脱糖基化

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
IF2.7
2025-12-010
PRE
Fisher, Troy D.; Compton, Philip D.; Robey, Matthew T.; Fellers, Ryan T.; Durbin, Kenneth R.; Kelleher, Neil L.
SPAP: Soluble Human Plasma Proteoform Analysis via Acetonitrile Precipitation and Top-Down Mass Spectrometry
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
IF2.7
2025-12-010
PRE
Sanchez, Aniel; Pla, Indira; Huang, Che-Fan; Kanchustambham, Vijaya Lakshmi; Hollas, Michael A. R.; Greer, Joseph B.; Ladner, Daniela P.; Peterson, Katrina N.; Fisher, Troy D.; Su, Taojunfeng; Le, Nhat Hoang Van; Mattamana, Basil Baby; Faull, Peter Allen; Polineni, Praneet; Barrios, Paola; Banea, Therese Elaine; Melani, Rafael D.; Caldwell, Michael A.; Mcgee, John P.; Forte, Eleonora; Kelleher, Neil L.
Nucleosome context regulates chromatin reader preference

核小体环境调控染色质读码器偏好

NUCLEIC ACIDS RESEARCH
IF13.1
2025-11-110
PRE
Marunde, Matthew R.; Popova, Irina K.; Hall, Nathan W.; Vaidya, Anup; Bone, James R.; Boone, Brandon A.; Brown, Peter J.; Ezell, Ryan J.; Firestone, Tessa M.; Fuchs, Harrison A.; Gibson, Elisa; Gillespie, Zachary B.; Gloor, Susan L.; Hickman, Allison R.; Howard, Sarah A.; Husby, Natalia Ledo; Hsiung, Victoria T.; Johnstone, Andrea L.; Khan, Laiba F.; Krajewski, Krzysztof; Lee, Alexander S.; Mcanarney, Eileen T.; Maier, Keith E.; Maryanski, Danielle N.; McCuiston, Jamie L.; Noll, Kelsey E.; Novitzky, Katherine; Patteson, Emily F.; Rodriguez, Keli L.; Sanchez, Julio C.; Schachner, Luis F.; Smith, Catherine E.; Sun, Lu; Taylor, Hailey F.; Watson, Rachel; Willis, Hannah E.; Musselman, Catherine A.; Venters, Bryan J.; Cheek, Marcus A.; Meiners, Matthew J.; Sun, Zu-Wen; Kelleher, Neil L.; Cowles, Martis W.; Weinzapfel, Ellen N.; Keogh, Michael-Christopher; Burg, Jonathan M.
Intact Mass Profiling Reveals Phospho-Proteoforms of the Catenins (85–110 kDa) Regulated by Actomyosin Contractility

完整质量分析揭示了由肌动球蛋白收缩性调控的连接蛋白（85–110 kDa）的磷酸化蛋白质变体。

Angewandte Chemie International Edition
IF16.9
2025-10-290
OAAI
Che-Fan Huang; Taojunfeng Su; Annette S. Flozak; Cara J. Gottardi; Neil L. Kelleher
A needed nomenclature for nucleosomes

核小体所需的命名法

Molecular Cell
IF16.6
2025-10-020
PRE
Michael-Christopher Keogh; Genevieve Almouzni; Andrew J. Andrews; Karim-Jean Armache; Cheryl H. Arrowsmith; Sung Hee Baek; Mark T. Bedford; Emily Bernstein; Jacques Côté; Yael David; John M. Denu; Beat Fierz; Benjamin A. Garcia; Karen C. Glass; Or Gozani; Kristian Helin; Steven Henikoff; Ole N. Jensen; Steven Z. Josefowicz; Neil L. Kelleher; Tatiana G. Kutateladze; Herbert H. Lindner; Chao Lu; Karolin Luger; Parag Mallick; Catherine A. Musselman; Tom W. Muir; Ljiljana Paša-Tolić; Robert Schneider; Xiaobing Shi; Yang Shi; Simone Sidoli; Lloyd M. Smith; Jessica K. Tyler; Cynthia Wolberger; Jerry L. Workman; Brian D. Strahl; Nicolas L. Young
Next-generation protein sequencing and individual ion mass spectrometry enable complementary analysis of interleukin-6

下一代蛋白质测序和单离子质谱技术能够实现白细胞介素-6的互补性分析。

Analytical and Bioanalytical Chemistry
IF3.8
2025-10-010
OA
Kenneth A. Skinner; Troy D. Fisher; Andrew Lee; Taojunfeng Su; Eleonora Forte; Aniel Sanchez; Michael A. Caldwell; Neil L. Kelleher
Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine

通过直接共价攻击CaaX盒半胱氨酸来阻断KRAS4b的C末端加工

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2025-05-090
OA
Maciag, Anna E.; Yang, Yue; Sharma, Alok K.; Turner, David M.; Dehart, Caroline J.; Abdelkarim, Hazem; Fan, Lixin; Smith, Brian P.; Kumari, Vandana; Dyba, Marcin; Rigby, Megan; Badillo, Jean A. Castillo; Adams, Lauren; Fornelli, Luca; Fox, Stephen; Brafman, Alla; Turbyville, Thomas; Gillette, William; Messing, Simon; Agamasu, Constance; Wolfe, Andrew L.; Gysin, Stephan; Chan, Albert H.; Simanshu, Dhirendra K.; Esposito, Dominic; Chertov, Oleg; Stephen, Andrew G.; Arkin, Michelle; Renslo, Adam; Kelleher, Neil L.; Gaponenko, Vadim; Lightstone, Felice C.; Nissley, Dwight, V; McCormick, Frank
Elevated neuroinflammation, autoimmunity, and altered IgG glycosylation profile in the cerebral spinal fluid of severe COVID-19 patients

严重COVID-19患者脑脊液中神经炎症、自身免疫水平升高，以及IgG糖基化谱改变。

BRAIN BEHAVIOR AND IMMUNITY
IF7.6
2025-04-170
PRE
Shull, Tanner; Bhimalli, Pavan; Welninski, Samantha; Cho, Byoung-Kyu; Mattamana, Basil; Arivalagan, Jaison; Tarhoni, Imad; Goo, Young Ah; Schneider, Julie A.; Agrawal, Sonal; Bennett, David A.; Leurgans, Sue; Patel, Mayur B.; Ely, E. Wesley; Kelleher, Neil L.; Borgia, Jeffrey A.; Schneider, Jeffrey R.; Al-Harthi, Lena
Native top-down proteomics enables discovery in endocrine-resistant breast cancer

本土自上而下蛋白质组学实现了内分泌抵抗性乳腺癌的发现

NATURE CHEMICAL BIOLOGY
IF13.7
2025-04-040
PRE
Gomes, Fabio P.; Durbin, Kenneth R.; Schauer, Kevin; Nwachukwu, Jerome C.; R. Kobylski, Robin; Njeri, Jacqline W.; Seath, Ciaran P.; Saviola, Anthony J.; McClatchy, Daniel B.; Diedrich, Jolene K.; Garrett, Patrick T.; Papa, Alexandra B.; Ciolacu, Ianis; Kelleher, Neil L.; Nettles, Kendall W.; Yates III, John R.
Proteoform-predictor: Increasing the Phylogenetic Reach of Top-Down Proteomics
JOURNAL OF PROTEOME RESEARCH
IF3.6
2025-03-010
PRE
Su, Taojunfeng; Fellers, Ryan T.; Greer, Joseph B.; Leduc, Richard D.; Thomas, Paul M.; Kelleher, Neil L.

Research Directions

The data has not been retrieved yet.
P
Paul M. Thomas
H-index:59Papers:186Citations:1.0万
R
Ryan T. Fellers
H-index:35Papers:91Citations:4,088
P
Philip D. Compton
H-index:33Papers:66Citations:4,104
R
Richard D. LeDuc
H-index:39Papers:115Citations:1.3万
K
Kenneth R. Durbin
H-index:30Papers:84Citations:3,464
R
Rafael D. Melani
H-index:23Papers:91Citations:1,875
B
Bryan P. Early
H-index:26Papers:73Citations:3,442
J
Jared O. Kafader
H-index:20Papers:61Citations:1,245
L
Luca Fornelli
H-index:36Papers:105Citations:4,358
I
Ioanna Ntai
H-index:29Papers:52Citations:2,787