Not logged inPatient-derived tumor-oids recapitulate the tumor microenvironment and allow for pre-clinical drug screening across the entire spectrum of pediatric brain tumors
Wink, Kelsey; Adam, Tiffany; Serhan, Habib; Beale, David R.; Beck, Maxwell; Wadden, Jack; Gehrand, Ashley; Prensner, John; Upadhyaya, Santhosh; Franson, Andrea; Chen, Kevin; Marupudi, Neena; Garton, Hugh; Magge, Suresh N.; Al-Holou, Wajd; Venneti, Sriram; Mody, Rajen; Chinnaiyan, Arul; Rood, Brian R.; Nazarian, Javad; Mueller, Sabine; Mitra, Siddhartha; Green, Adam L.; Kraya, Adam; Merrill, Nathan; Merajver, Sofia D.; Resnick, Adam; Koptyra, Mateus; Koschmann, Carl .png)
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SaveCombinatorial targeting of avapritinib-driven MAPK activation in pediatric high-grade gliomaSchwark, Kallen; Miclea, Madeline; Patel, Tirth; Kong, Seongbae; Stanczak, Alina; Lau, Benison; Cartaxo, Rodrigo; Messinger, Dana; Doherty, Robert; Ji, Sunjong; Wadden, Jack; Clausen, Madison; Momen, Fareen; Adam, Tiffany; Wink, Kelsey; Hutchinson, Aria; Niculcea, Michael; Serhan, Habib; Merrill, Nathan; Edmonds, Amy; Mayr, Lisa; Neyazi, Sina; Munoz, Denise; Nuechterlein, Nicholas; Fernandez, Ester Calvo; Califano, Andrea; Pavisic, Jovana; Garton, Hugh; Rao, Rama; Upadhyaya, Santhosh; Skrypek, Mary; Bendel, Anne; Lobbous, Mina; Klawinski, Darren; Merajver, Sofia; Koptyra, Mateusz; Resnick, Adam; Nazarian, Javad; Venneti, Sriram; Waszak, Sebastian; Chavez, Lukas; Beck, Alexander; Gojo, Johannes; Filbin, Mariella; Coppe, Jean-Philippe; Koschmann, Carl Share Save Tail ligation recombinase polymerase amplification sequencing (TLDRseq) enables sensitive, same-day, multi-gene sequencing for plasma-based detection and timely monitoring of brain tumor ctDNAWadden, Jack; Aittaleb, Rayan; Adam, Tiffany; Jackson, Conner; John, Vishal; Lau, Benison; Calvert, Rebecca; Franson, Andrea; Mody, Rajen; Prensner, John; Upadhyaya, Santhosh; Koschmann, Carl Share Save Updates in Diagnostic Techniques and Experimental Therapies for Diffuse Intrinsic Pontine GliomaMcveigh, Luke; Patel, Tirth; Miclea, Madeline; Schwark, Kallen; Ajaero, Diala; Momen, Fareen; Clausen, Madison; Adam, Tiffany; Aittaleb, Rayan; Wadden, Jack; Lau, Benison; Franson, Andrea T.; Koschmann, Carl; Marupudi, Neena I. Share Save SEQUENCING OF DNA RECOVERED FROM BRAIN TUMOR BIOPSY SURGICAL WASTE IMPROVES SENSITIVITY OF RAPID IDH/TP53-MUTANT TUMOR DIAGNOSESWadden, Jack; Adam, Tiffany; Cartaxo, Rodrigo; Niculcea, Michael; Kong, Seongbae; John, Vishal; Tripathy, Arushi; Bird, Cylaina; Nazarian, Javad; Heth, Jason; Muraszko, Karin; Marupudi, Neena; Magge, Suresh; Garton, Hugh; Al-Holou, Wajd; Koschmann, Carl Share Save Liquid biopsy in H3K27M diffuse midline gliomaPatel, Jina; Aittaleb, Rayan; Doherty, Robert; Gera, Ananya; Lau, Benison; Messinger, Dana; Wadden, Jack; Franson, Andrea; Saratsis, Amanda; Koschmann, Carl Share Save Share Save Ultra-rapid somatic variant detection via real-time targeted amplicon sequencingWadden, Jack; Newell, Brandon S.; Bugbee, Joshua; John, Vishal; Bruzek, Amy K.; Dickson, Robert P.; Koschmann, Carl; Blaauw, David; Narayanasamy, Satish; Das, Reetuparna Share Save Share Save Serial H3K27M cell-free tumor DNA (cf-tDNA) tracking predicts ONC201 treatment response and progression in diffuse midline gliomaCantor, Evan; Wierzbicki, Kyle; Tarapore, Rohinton S.; Ravi, Karthik; Thomas, Chase; Cartaxo, Rodrigo; Yadav, Viveka Nand; Ravindran, Ramya; Bruzek, Amy K.; Wadden, Jack; John, Vishal; Babila, Clarissa May; Cummings, Jessica R.; Kawakibi, Abed Rahman; Ji, Sunjong; Ramos, Johanna; Paul, Alyssa; Walling, Dustin; Leonard, Marcia; Robertson, Patricia; Franson, Andrea; Mody, Rajen; Garton, Hugh J. L.; Venetti, Sriram; Odia, Yazmin; Kline, Cassie; Vitanza, Nicholas A.; Khatua, Soumen; Mueller, Sabine; Allen, Joshua E.; Gardner, Sharon L.; Koschmann, Carl Share Save SquiggleNet: real-time, direct classification of nanopore signalsBao, Yuwei; Wadden, Jack; Erb-Downward, John R.; Ranjan, Piyush; Zhou, Weichen; McDonald, Torrin L.; Mills, Ryan E.; Boyle, Alan P.; Dickson, Robert P.; Blaauw, David; Welch, Joshua D. Share Save SERIAL PLASMA AND CSF CELL-FREE TUMOR DNA (CF-TDNA) TRACKING IN DIFFUSE MIDLINE GLIOMA PATIENTS UNDERGOING TREATMENT WITH ONC201Cantor, Evan; Wierzbicki, Kyle; Tarapore, Rohinton S.; Thomas, Chase; Cartaxo, Rodrigo; Yadav, Viveka Nand; Bruzek, Amy K.; Wadden, Jack; Babilla, Clarissa May; Kawakibi, Abed Rhaman; Ji, Sunjong; Ramos, Johanna; Paul, Alyssa; Wolfe, Ian; Leonard, Marcia; Robertson, Partricia; Franson, Andrea; Mody, Rajen; Garton, Hugh; Odia, Yazmin; Kline, Cassie; Vitanza, Nicholas A.; Khatua, Soumen; Mueller, Sabine; Allen, Joshua E.; Gardner, Sharon; Koschmann, Carl Share Save Share Save Share Save Share Save 
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