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Ismail Hassan Ismail

11560 university avenue

17H-index
50Paper Count
1.9KCitation Count
Published Papers 22
Publication Date
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Pathogenic variants in MAEA disrupt DNA replication fork stability and are associated with developmental abnormalities in humans
errScience Advances
IF12.5
err2025-08-29
err0
errOAAI
errElham Zeinali; Fatemeh Mashayekhi; Rabih Abou Farraj; Talah Hasanni; Marie-Christine Caron; Yan Coulombe; Amira Fitieh; J. N. Mark Glover; Jean-Yves Masson; Ismail Hassan Ismail
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PNKP safeguards stalled replication forks from nuclease-dependent degradation stress
errCELL REPORTS
IF6.9
err2024-12-01
err0
errOAAI
errMashayekhi, Fatemeh; Ganje, Cassandra; Caron, Marie-Christine; Heyza, Joshua R.; Gao, Yuandi; Zeinali, Elham; Fanta, Mesfin; Li, Lei; Ali, Jana; Mersaoui, Sofiane Yacine; Schmidt, Jens C.; Godbout, Roseline; Masson, Jean-Yves; Weinfeld, Michael; Ismail, Ismail Hassan
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errSave
CDK-dependent phosphorylation regulates PNKP function in DNA replication
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-11-01
err1
PREAI
errMashayekhi, Fatemeh; Zeinali, Elham; Ganje, Cassandra; Fanta, Mesfin; Li, Lei; Godbout, Roseline; Weinfeld, Michael; Ismail, Ismail Hassan
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Targeting Dectin-1 and or VISTA enhances anti-tumor immunity in melanoma but not colorectal cancer model
errCELLULAR ONCOLOGY
IF4.8
err2024-04-26
err2
errOAAI
errMashhouri, Siavash; Rahmati, Amirhossein; Azimi, Ako; Fava, Roy A.; Ismail, Ismail Hassan; Walker, John; Elahi, Shokrollah
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The role of RNF138 in DNA end resection is regulated by ubiquitylation and CDK phosphorylation
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errLocke, Andrew J.; Farraj, Rabih Abou; Tran, Caroline; Zeinali, Elham; Mashayekhi, Fatemeh; Ali, Jana Yasser Hafez; Glover, J. N. Mark; Ismail, Ismail Hassan
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errSave
Unravelling the Role of PARP1 in Homeostasis and Tumorigenesis: Implications for Anti-Cancer Therapies and Overcoming Resistance
errCELLS
IF5.2
err2023-07-21
err0
errOAAI
errLovsund, Taylor; Mashayekhi, Fatemeh; Fitieh, Amira; Stafford, James; Ismail, Ismail Hassan
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Cellular mechanism of action of 2-nitroimidazoles as hypoxia-selective therapeutic agents
errREDOX BIOLOGY
IF11.9
err2022-06-01
err17
errOAAI
errBin Rashed, Faisal; Diaz-Dussan, Diana; Mashayekhi, Fatemeh; Macdonald, Dawn; Nation, Patrick Nicholas; Yang, Xiao-Hong; Sokhi, Sargun; Stoica, Alexandru Cezar; El-Saidi, Hassan; Ricardo, Carolynne; Narain, Ravin; Ismail, Ismail Hassan; Wiebe, Leonard Irving; Kumar, Piyush; Weinfeld, Michael
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errSave
BMI-1 regulates DNA end resection and homologous recombination repair
errCELL REPORTS
IF6.9
err2022-03-01
err20
errOAAI
errFitieh, Amira; Locke, Andrew J.; Mashayekhi, Fatemeh; Khaliqdina, Fajr; Sharma, Ajit K.; Ismail, Ismail Hassan
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errSave
SUMOylation mediates CtIP's functions in DNA end resection and replication fork protection
errNUCLEIC ACIDS RESEARCH
IF13.1
err2021-01-06
err15
errOAAI
errLocke, Andrew J.; Hossain, Lazina; McCrostie, Glynnis; Ronato, Daryl A.; Fitieh, Amira; Rafique, Tanzeem Ahmed; Mashayekhi, Fatemeh; Motamedi, Mobina; Masson, Jean-Yves; Ismail, Ismail Hassan
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RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2016-04-01
err32
errOAAI
errHodge, Curtis D.; Ismail, Ismail H.; Edwards, Ross A.; Hura, Greg L.; Xiao, Andrew T.; Tainer, John A.; Hendzel, Michael J.; Glover, J. N. Mark
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errSave
BCL10 is recruited to sites of DNA damage to facilitate DNA double-strand break repair
errCELL CYCLE
IF3.4
err2016-01-15
err12
errOAAI
errIsmail, Ismail Hassan; Dronyk, Ashley; Hu, Xiuying; Hendzel, Michael J.; Shaw, Andrew R.
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errSave
The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice
errNATURE CELL BIOLOGY
IF19.1
err2015-10-26
err121
PREAI
errIsmail, Ismail Hassan; Gagne, Jean-Philippe; Genois, Marie-Michelle; Strickfaden, Hilmar; McDonald, Darin; Xu, Zhizhong; Poirier, Guy G.; Masson, Jean-Yves; Hendzel, Michael J.
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Polycomb group proteins in the DNA damage response A link between radiation resistance and stemness
errCELL CYCLE
IF3.4
err2014-10-28
err74
errOAAI
errGieni, Randall S.; Ismail, Ismail H.; Campbell, Stuart; Hendzel, Michael J.
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errSave
Polycomb repressive complex 2 contributes to DNA double-strand break repair
errCELL CYCLE
IF3.4
err2014-10-27
err122
errOAAI
errCampbell, Stuart; Ismail, Ismail Hassan; Young, Leah C.; Poirier, Guy G.; Hendzel, Michael J.
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errSave
Germline Mutations in BAP1 Impair Its Function in DNA Double-Strand Break Repair
errCANCER RESEARCH
IF16.6
err2014-08-13
err173
errOAAI
errIsmail, Ismail Hassan; Davidson, Riley; Gagne, Jean-Philippe; Xu, Zhi Zhong; Poirier, Guy G.; Hendzel, Michael J.
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A Small Molecule Inhibitor of Polycomb Repressive Complex 1 Inhibits Ubiquitin Signaling at DNA Double-strand Breaks
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2013-09-01
err92
errOAAI
errIsmail, Ismail Hassan; McDonald, Darin; Strickfaden, Hilmar; Xu, Zhizhong; Hendzel, Michael J.
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errSave
CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage
errNUCLEIC ACIDS RESEARCH
IF13.1
err2012-02-08
err121
errOAAI
errIsmail, Ismail Hassan; Gagne, Jean-Philippe; Caron, Marie-Christine; McDonald, Darin; Xu, Zhizhong; Masson, Jean-Yves; Poirier, Guy G.; Hendzel, Michael J.
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errSave
BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair
errJOURNAL OF CELL BIOLOGY
IF6.4
err2010-10-04
err263
errOAAI
errIsmail, Hassan Ismail; Andrin, Christi; McDonald, Darin; Hendzel, Michael J.
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An optimized method for measurement of gamma-H2AX in blood mononuclear and cultured cells
errNATURE PROTOCOLS
IF16
err2008-06-26
err126
PREAI
errMuslimovic, Aida; Ismail, Ismail Hassan; Gao, Yue; Hammarsten, Ola
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errSave
An optimized method for detecting gamma-H2AX in blood cells reveals a significant interindividual variation in the gamma-H2AX response among humans
errNUCLEIC ACIDS RESEARCH
IF13.1
err2007-02-06
err163
errOAAI
errIsmail, Ismail Hassan; Wadhra, Tabasum Imran; Hammarsten, Ola
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Research Directions

No research directions
Co-authors
Cooperation Journals
J
John A. Tainer
H-index: 123 · Papers: 806
G
Guy G. Poirier
H-index: 97 · Papers: 434
M
Michael J. Hendzel
H-index: 71 · Papers: 216
J
Jean‐Yves Masson
H-index: 61 · Papers: 288
J
Jonas Nygren
H-index: 57 · Papers: 203
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