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C

Clement C. Zai

Centre for Addiction and Mental Health

52H-index
403Paper Count
3.2WCitation Count
Published Papers 196
Publication Date
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Distribution of Cytochrome P450 Metabolizer Status and Allelic Variants in Individuals with Mental Health Disorders in Ontario, Canada: Répartition du statut métabolique du cytochrome P450 et des variantes alléliques chez les personnes atteintes de problèmes de santé mentale en Ontario, au Canada
errCANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE
IF3.8
err2026-06-04
err0
PREAI
errMegana Thamilselvan; Alex J. Coulter; Deanna Herbert; Anashe Shahmirian; Nicole King; Daniel J. Müller; Arun Kumar Tiwari; Clement C. Zai; James L. Kennedy
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Autism spectrum disorder trios from consanguineous populations are enriched for rare homozygous variants, identifying 32 new candidate genes
errScientific Reports
IF3.9
err2026-03-21
err0
errOAAI
errRicardo Harripaul; Ansa Rabia; Nasim Vasli; Anna Mikhailov; Ashlyn Rodrigues; Stephen F. Pastore; Tahir Muhammad; Thulasi Thiruvallur Madanagopal; Aisha Nasir Hashmi; Clinton Tran; Cassandra Stan; Katherine Aw; Clement C. Zai; Maleeha Azam; Saqib Mahmood; Abolfazl Heidari; Raheel Qamar; Leon French; Shreejoy Tripathy; Zehra Agha; Muhammad Iqbal; Majid Ghadami; Susan L. Santangelo; Bita Bozorgmehr; Laila Al Ayadhi; Roksana Sasanfar; Shazia Maqbool; Arsalan Hassan; James A. Knowles; Muhammad Ayub; John B. Vincent
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Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling
errNature Genetics
IF29
err2026-02-03
err0
errOAAI
errNora I. Strom; Brad Verhulst; Silviu-Alin Bacanu; Rosa Cheesman; Kirstin L. Purves; Hüseyin Gedik; Brittany L. Mitchell; Alex S. Kwong; Annika B. Faucon; Kritika Singh; Sarah Medland; Lucia Colodro-Conde; Kristi Krebs; Per Hoffmann; Stefan Herms; Jan Gehlen; Stephan Ripke; Swapnil Awasthi; Teemu Palviainen; Elisa M. Tasanko; Roseann E. Peterson; Daniel E. Adkins; Andrey A. Shabalin; Mark J. Adams; Matthew H. Iveson; Archie Campbell; Laurent F. Thomas; Bendik S. Winsvold; Ole Kristian Drange; Sigrid Børte; Abigail R. ter Kuile; Joonas Naamanka; Tan-Hoang Nguyen; Sandra M. Meier; Elizabeth C. Corfield; Laurie Hannigan; Daniel F. Levey; Darina Czamara; Heike Weber; Karmel W. Choi; Giorgio Pistis; Baptiste Couvy-Duchesne; Sandra Van der Auwera; Alexander Teumer; Robert Karlsson; Miguel Garcia-Argibay; Donghyung Lee; Rujia Wang; Ottar Bjerkeset; Eystein Stordal; Julia Bäckman; Giovanni A. Salum; Clement C. Zai; James L. Kennedy; Gwyneth Zai; Arun K. Tiwari; Stefanie Heilmann-Heimbach; Börge Schmidt; Jaakko Kaprio; Martin M. Kennedy; Joseph Boden; Alexandra Havdahl; Christel M. Middeldorp; Fabiana L. Lopes; Nirmala Akula; Francis J. McMahon; Elisabeth B. Binder; Lydia Fehm; Andreas Ströhle; Enrique Castelao; Henning Tiemeier; Dan J. Stein; David Whiteman; Catherine Olsen; Zachary Fuller; Xin Wang; Naomi R. Wray; Enda M. Byrne; Glyn Lewis; Nicholas J. Timpson; Lea K. Davis; Ian B. Hickie; Nathan A. Gillespie; Lili Milani; Johannes Schumacher; David P. Woldbye; Andreas J. Forstner; Markus M. Nöthen; Iiris Hovatta; John Horwood; William E. Copeland; Hermine H. Maes; Andrew M. McIntosh; Ole A. Andreassen; John-Anker Zwart; Ole Mors; Anders D. Børglum; Preben B. Mortensen; Helga Ask; Ted Reichborn-Kjennerud; Jackob M. Najman; Murray B. Stein; Joel Gelernter; Yuri Milaneschi; Brenda W. Penninx; Dorret I. Boomsma; Eduard Maron; Angelika Erhardt-Lehmann; Christian Rück; Tilo T. Kircher; Christiane A. Melzig; Georg W. Alpers; Volker Arolt; Katharina Domschke; Jordan W. Smoller; Martin Preisig; Nicholas G. Martin; Michelle K. Lupton; Annemarie I. Luik; Andreas Reif; Hans J. Grabe; Henrik Larsson; Patrik K. Magnusson; Albertine J. Oldehinkel; Catharina A. Hartman; Gerome Breen; Anna R. Docherty; Hilary Coon; Rupert Conrad; Kelli Lehto; Jürgen Deckert; Thalia C. Eley; Manuel Mattheisen; John M. Hettema
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Greater polygenic risk for cardiovascular disease is associated with reduced executive function among youth with bipolar disorder
errJournal of Affective Disorders
IF4.9
err2025-12-19
err0
PREAI
errNidhi P. Kulkarni; Clement C. Zai; Mikaela K. Dimick; Alysha A. Sultan; L. Trevor Young; Benjamin I. Goldstein
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Defining and Assessing International Classification of Disease Suicidality Phenotypes for Genetic Studies
errPsychiatry Research
IF3.9
err2025-10-02
err0
errOAAI
errEric T. Monson; Sarah M.C. Colbert; Peter B. Barr; Cosmin A. Bejan; Ole A. Andreassen; Olatunde O. Ayinde; Zuriel Ceja; Hilary Coon; Emily DiBlasi; Anastasia Izotova; Erin A. Kaufman; Maria Koromina; Woojae Myung; John I. Nurnberger; Alessandro Serretti; Jordan W. Smoller; Murray B. Stein; Clement C. Zai; Mihaela Aslan; Tim B. Bigdeli; Philip D. Harvey; Nathan A. Kimbrel; Pujan R. Patel; Douglas M. Ruderfer; Anna R. Docherty; Niamh Mullins; J. John Mann
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Defining suicidality phenotypes for genetic studies: perspectives of the Psychiatric Genomics Consortium Suicide Working Group
errMolecular Psychiatry
IF10.1
err2025-09-25
err0
errOAAI
errSarah M. C. Colbert; Eric T. Monson; Ole A. Andreassen; Olatunde O. Ayinde; Peter B. Barr; Cosmin A. Bejan; Zuriel Ceja; Hilary Coon; Emily DiBlasi; Howard J. Edenberg; Joel Gelernter; Alexander Hatoum; Anastasia Izotova; Emma C. Johnson; Erin A. Kaufman; Henry R. Kranzler; Maria Koromina; Kelli Lehto; Woojae Myung; John I. Nurnberger; Alessandro Serretti; Jordan W. Smoller; Murray B. Stein; Clement C. Zai; Annette Erlangsen; Marie Gaine; Lourdes Martorell; Reeteka Sud; Claudio Toma; Tim B. Bigdeli; Nathan A. Kimbrel; Douglas Ruderfer; Anna R. Docherty; J. John Mann; Niamh Mullins
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Neurostructural Correlates of Polygenic Risk for Coronary Artery Disease in Relation to Youth Bipolar Disorder
errBipolar Disorders
IF4.5
err2025-09-24
err0
errOAAI
errNidhi P. Kulkarni; Clement C. Zai; Kody G. Kennedy; Megan Mio; L. Trevor Young; Bradley J. MacIntosh; Benjamin I. Goldstein
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errSave
GenoStaR: An R Package for Genotype to Star Allele Conversion for Major Cytochrome P450 Family of Genes
errClinical Pharmacology & Therapeutics
IF5.5
err2025-09-05
err0
errOAAI
errAlex J. Coulter; Megana Thamilselvan; James L. Kennedy; Clement C. Zai; Arun K. Tiwari
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errSave
Dopamine D3 receptor gene is associated with obsessive-compulsive disorder and antidepressant response
errprogress in neuro psychopharmacology biological psychiatry
IF0
err2025-06-11
err0
PREAI
errGwyneth Zai; Clement C. Zai; Eliza Burroughs; Paul D. Arnold; James L. Kennedy; Margaret A. Richter
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Impact of repetitive transcranial magnetic stimulation on clinical and cognitive outcomes, and brain-derived neurotrophic factor levels in treatment-resistant depression
errFRONTIERS IN PSYCHIATRY
IF3.2
err2025-04-08
err0
errOAAI
errGinelli, Enrico; Sanna, Lucia; Paribello, Pasquale; Isayeva, Ulker; Corona, Giorgio; Zai, Clement C.; Manca, Daniela; Iaselli, Maria Novella; Collu, Roberto; Pinna, Federica; Scherma, Maria; Manchia, Mirko; Fadda, Paola; Carpiniello, Bernardo
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Pharmacogenetics of obsessive-compulsive disorder: Investigations of intragenic and regulatory region genetic variations
errPROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
IF3.9
err2025-04-02
err0
PREAI
errZai, Gwyneth; Zai, Clement C.; Goncalves, Vanessa F.; Wigg, Karen; Lochner, Christine; Stein, Dan J.; Mathews, Carol A.; Kennedy, James L.; Richter, Margaret A.
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Polygenic risk scores in relation to suicidality among youth with or at risk for bipolar disorder
errJOURNAL OF AFFECTIVE DISORDERS
IF4.9
err2025-04-01
err0
PREAI
errZai, Clement C.; Dimick, Mikaela K.; Young, L. Trevor; Kennedy, James L.; Goldstein, Benjamin I.
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errSave
Characterizing features affecting local ancestry inference performance in admixed populations
errAMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
err2025-02-01
err0
errOAAI
errHonorato-Mauer, Jessica; Shah, Nirav N.; Maihofer, Adam X.; Zai, Clement C.; Belangero, Sintia; Nievergelt, Caroline M.; Santoro, Marcos; Atkinson, E. G.
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errSave
Neurocognitive correlates of polygenic risk for bipolar disorder among youth with and without bipolar disorder
errJOURNAL OF AFFECTIVE DISORDERS
IF4.9
err2025-01-01
err0
PREAI
errJiang, Xinyue; Zai, Clement; Mio, Megan; Dimick, Mikaela K.; Sultan, Alysha A.; Young, L. Trevor; Goldstein, Benjamin I.
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errSave
Tardive dyskinesia versus tardive syndrome. What is in a name?
errPARKINSONISM & RELATED DISORDERS
IF3.4
err2025-01-01
err0
PREAI
errFrei, Karen; Scott, Alicia; Caroff, Stanley N.; Jankovic, Joseph; Ondo, William; Citrome, Leslie; Hauser, Robert; Friedman, Joseph H.; Bhidayasiri, Roongroj; Sajatovic, Martha; Alters, Dennis; Meyer, Jonathan; Factor, Stuart; Tan, E. K.; Remington, G.; Glick, Ira; Fernandez, Hubert; Comella, Cynthia; Kane, John; Mcevoy, Joseph; Miller, Delwyn; Zai, Clement C.; Lindenmayer, J. P.; Trosch, Richard; Truong, Daniel D.
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Sex-dependent association study of complement C4 gene with treatment-resistant schizophrenia and hospitalization frequency
errPSYCHIATRY RESEARCH
IF3.9
err2024-12-01
err0
errOAAI
errTeymouri, Kowsar; Ebrahimi, Mahbod; Chen, Cheng C.; Sriretnakumar, Venuja; Mohiuddin, Ayeshah G.; Tiwari, Arun K.; Pouget, Jennie G.; Zai, Clement C.; Kennedy, James L.
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Psychiatric Polygenic Risk Scores Across Youth With Bipolar Disorder, Youth at High Risk for Bipolar Disorder, and Controls
errJOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
IF9.5
err2024-11-01
err4
PREAI
errJiang, Xinyue; Zai, Clement C.; Dimick, Mikaela K.; Kennedy, James L.; Young, L. Trevor; Birmaher, Boris; Goldstein, Benjamin I.
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GENETIC CORRELATION OF CHILDHOOD AGGRES-SION WITH MENTAL AND GENERAL HEALTH TRAITS
errEUROPEAN NEUROPSYCHOPHARMACOLOGY
IF6.7
err2024-10-01
err0
PREAI
errKoyama, Emiko; Kant, Tuana; Takata, Atsushi; Kennedy, James L.; Zai, Clement
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Analysis of the complement component C4 gene with schizophrenia subphenotypes
errSCHIZOPHRENIA RESEARCH
IF3.5
err2024-09-01
err1
errOAAI
errChen, Cheng C.; Howie, Joshua; Ebrahimi, Mahbod; Teymouri, Kowsar; Woo, Julia J.; Tiwari, Arun K.; Zai, Clement C.; Kennedy, James L.
errShare
errSave
BDNF plasma concentrations, cognitive test performances and lifetime suicide ideation in psychotic disorders: a secondary analysis.
errEUROPEAN PSYCHIATRY
IF6.7
err2024-08-27
err0
errOAAI
errParibello, P.; Manchia, M.; Isayeva, U.; Collu, R.; Federica, P.; Scherma, M.; Pisanu, C.; Meloni, A.; Zai, C. C.; Congiu, D.; Squassina, A.; Fratta, W.; Fadda, P.; Carpiniello, B.
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Research Directions

No research directions
Co-authors
Cooperation Journals
R
Ronald C. Kessler
H-index: 277 · Papers: 1.7K
D
Dan J. Stein
H-index: 249 · Papers: 4.2K
M
Mark J. Daly
H-index: 224 · Papers: 1.2K
N
Nicholas G. Martin
H-index: 221 · Papers: 2.8K
B
Brenda W.J.H. Penninx
H-index: 210 · Papers: 1.8K
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