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Christian J. Kastrup

versiti blood research institute

29H-index
112Paper Count
3.2KCitation Count
Published Papers 60
Publication Date
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Engineering the blood: Lipid nanoparticle platforms for ex vivo immune and hematopoietic cell therapies
errJournal of Controlled Release
IF11.5
err2026-07-27
err0
PREAI
errYongjoo Byeon; Nuoya Peng; Eun Bee Oh; Eunbin Kim; Dayoung Gu; Hyunsoo Kang; Katherine E. Badior; Tong-Shin Chang; Christian J. Kastrup; Hyukjin Lee
errShare
errSave
Clot contraction of whole blood diminishes during storage and can be restored by adding platelets
errTransfusion
IF2
err2026-07-06
err0
PREAI
errHalen Turner; Monica Seadler; Youjie Zhang; Matteo Ferraresso; Christian Kastrup
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errSave
Anti-fibrinolytic strategies improve liver regeneration in mice and reduce post-hepatectomy liver failure in patients
errBlood
IF23.1
err2026-06-15
err0
PREAI
errZhihao Li; Zimu Wei; Dafna J. Groeneveld; Amy W Strilchuk; Matthew J. Flick; Yawen Dong; Vanja Podrascanin; Mark J. Truty; Michael L. Kendrick; Sean P. Cleary; Susanne G. Warner; Rory L. Smoot; Alice Assinger; Christian J Kastrup; Paul Karanicolas; James P. Luyendyk; Patrick P. Starlinger
errShare
errSave
Precipitation-Based Encapsulation of Fibrinogen in Calcium Carbonate for Non-Compressible Hemorrhage Control
errPharmaceuticals
IF4.8
err2026-06-12
err0
errOAAI
errHenry T. Peng; Tristan Bonnici; Catherine Tenn; Christian J. Kastrup; Andrew Beckett
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errSave
Contraction of blood clots occurs during hemostasis and hemorrhagic shock to promote closure of lacerations
errBiomaterials
IF12.9
err2026-05-11
err0
PREAI
errMatteo Ferraresso; Nabil Ali Mohamad; Massimo F. Cau; Monica Seadler; Halen Turner; Francesca Ferraresso; Youjie Zhang; Thomas W. Carver; Chandrasekaran Nagaswami; Andrew Beckett; Henry T. Peng; Rustem I. Litvinov; John W. Weisel; Mattia Bacca; Christian J. Kastrup
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errSave
Extraterrestrial Regolith is Hemostatic and Potentially Suitable for Hemorrhage Control in Space
errResearch and Practice in Thrombosis and Haemostasis
IF3.4
err2026-01-05
err0
errOAAI
errNabil Ali-Mohamad; Ting-Hsuan Wang; Lih Jiin Juang; Nuoya Peng; Massimo F. Cau; Kevin Cannon; Christian J. Kastrup
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errSave
Depletion of Fibrinogen Suppresses Growth of Primary Tumors and Metastasis of Pancreatic Ductal Adenocarcinoma
errGastroenterology
IF25.1
err2025-12-23
err0
errOAAI
errNayela N. Chowdhury; Dana K. Mitchell; Kadri Kangro; Kierra Eldridge; Sara Abrahams; Francesca Ferraresso; Lih J. Juang; Silpa Gampala; Kylee Brewster; Alexey Revenko; Christian Kastrup; Paul R. Territo; D. Wade Clapp; Jia Wang; Jorge A. Belgodere; Omer Saeed; Sae Rome Choi; Bumsoo Han; Alisa S. Wolberg; Sha Cao
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errSave
Preclinical safety and bleeding evaluation in swine for an siRNA-lipid nanoparticle that prevents excess fibrinogen synthesis
errJournal of Thrombosis and Haemostasis
IF5
err2025-10-10
err0
PREAI
errMonica S. Seadler; Francesca Ferraresso; Halen M. Turner; Laura M. Ketelboeter; Youjie Zhang; Katherine Badior; William G. Hayssen; Taylor Chen; Amber L. Haugen; Massimo F. Cau; Madelaine Robertson; Chad Skaer; Muskan Bansal; Patrick B. Murphy; Marc de Moya; Mitchell R. Dyer; Christian J. Kastrup
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errSave
Reversing PAI-1 deficiency in blood using mRNA lipid nanoparticles
errMolecular Therapy Methods & Clinical Development
IF4.7
err2025-08-12
err0
errOAAI
errFrancesca Ferraresso; Chad W. Skaer; Katherine Badior; Serena M. Pulente; Manoj Paul; Laura Ketelboeter; Taylor H.S. Chen; Pieter R. Cullis; Sweta Gupta; Amy Shapiro; Erin E. Mulvihill; Christian J. Kastrup
errShare
errSave
Emulsion-Based Encapsulation of Fibrinogen with Calcium Carbonate for Hemorrhage Control
errJOURNAL OF FUNCTIONAL BIOMATERIALS
IF5.2
err2025-03-03
err0
errOAAI
errPeng, Henry T.; Bonnici, Tristan; Chen, Yanyu; Kastrup, Christian; Beckett, Andrew
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errSave
Genetic engineering of megakaryocytes from blood progenitor cells using messenger RNA lipid nanoparticles
errJOURNAL OF THROMBOSIS AND HAEMOSTASIS
IF5
err2025-01-01
err0
PREAI
errFeijuc, Jerry; Primbetova, Asel; Strong, Colton; Hay, Brenna N.; Hsu, Han-Hsuan; Hagner, Andrew; Foster, Leonard J.; Devine, Dana; Cullis, Pieter R.; Zandstra, Peter W.; Kastrup, Christian J.
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errSave
A Therapeutic siRNA Targeting Plasminogen Acts As a Long-Lasting Antifibrinolytic in Nonhuman Primates
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errStrilchuk, Amy W.; Juang, Lih Jiin; Winterborn, Andrew; Harpell, Lori; Pender, Abbey; Mo, Aomei; Babaha, Fateme; Kastrup, Christian J.; Lillicrap, David
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errSave
Rap1A Modulates Store-Operated Calcium Entry in the Lung Endothelium: A Novel Mechanism Controlling NFAT-Mediated Vascular Inflammation and Permeability
errARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
err2024-11-01
err0
PREAI
errKosuru, Ramoji; Romito, Olivier; Sharma, Guru Prasad; Ferraresso, Francesca; Nakhchi, Behshid Ghadrdoost; Yang, Kai; Mammoto, Tadanori; Mammoto, Akiko; Kastrup, Christian J.; Zhang, David X.; Goldspink, Paul H.; Trebak, Mohamed; Chrzanowska, Magdalena
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errSave
Regulation of hepatic inclusions and fibrinogen biogenesis by SEL1L-HRD1 ERAD
errNATURE COMMUNICATIONS
IF15.7
err2024-10-26
err0
errOAAI
errSong, Zhenfeng; Thepsuwan, Pattaraporn; Hur, Woosuk Steve; Torres, Mauricio; Wu, Shuangcheng Alivia; Wei, Xiaoqiong; Tushi, Nusrat Jahan; Wei, Juncheng; Ferraresso, Francesca; Paton, Adrienne W.; Paton, James C.; Zheng, Ze; Zhang, Kezhong; Fang, Deyu; Kastrup, Christian J.; Jaiman, Sunil; Flick, Matthew James; Sun, Shengyi
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errSave
Pharmacological depletion of fibrinogen suppresses the growth of primary tumors and liver metastasis of pancreatic cancer
errCANCER RESEARCH
IF16.6
err2024-09-15
err0
PREAI
errChowdhury, Nayela N.; Mitchell, Dana K.; Kangro, Kadri; Eldridge, Kierra; Abrahams, Sara; Ferraresso, Francesca; Juang, Lih J.; Gampala, Silpa; Brewster, Kylee; Revenko, Alexey; Kastrup, Christian; Territo, Paul R.; Clapp, D. Wade; Belgodere, Jorge A.; Han, Bumsoo; Wolberg, Alisa S.; Zhang, Chi; Flick, Matthew J.; Fishel, Melissa L.
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errSave
Suppressing upregulation of fibrinogen after polytrauma mitigates thrombosis in mice
errJOURNAL OF TRAUMA AND ACUTE CARE SURGERY
IF3.7
err2024-09-06
err0
PREAI
errSeadler, Monica S.; Ferraresso, Francesca; Bansal, Muskan; Haugen, Amber; Hayssen, William G.; Flick, Matthew J.; de Moya, Marc; Dyer, Mitchell R.; Kastrup, Christian J.
errShare
errSave
Protein is expressed in all major organs after intravenous infusion of mRNA-lipid nanoparticles in swine
errMOLECULAR THERAPY
IF12
err2024-09-01
err0
errOAAI
errFerraresso, Francesca; Badior, Katherine; Seadler, Monica; Zhang, Youjie; Wietrzny, Amanda; Cau, Massimo F.; Haugen, Amber; Rodriguez, Geoffrey G.; Dyer, Mitchell R.; Cullis, Pieter R.; Jan, Eric; Kastrup, Christian J.
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errSave
RNA therapeutics to control fibrinolysis: review on applications in biology and medicine
errJOURNAL OF THROMBOSIS AND HAEMOSTASIS
IF5
err2024-08-01
err1
PREAI
errFerraresso, Francesca; Leung, Jerry; Kastrup, Christian J.
errShare
errSave
Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2024-02-21
err6
errOAAI
errStrilchuk, Amy W.; Hur, Woosuk S.; Batty, Paul; Sang, Yaqiu; Abrahams, Sara R.; Yong, Alyssa S. M.; Leung, Jerry; Silva, Lakmali M.; Schroeder, Jocelyn A.; Nesbitt, Kate; de Laat, Bas; Moutsopoulos, Niki M.; Bugge, Thomas H.; Shi, Qizhen; Cullis, Pieter R.; Merricks, Elizabeth P.; Wolberg, Alisa S.; Flick, Matthew J.; Lillicrap, David; Nichols, Timothy C.; Kastrup, Christian J.
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errSave
Genetically engineered transfusable platelets using mRNA lipid nanoparticles
errSCIENCE ADVANCES
IF12.5
err2023-12-01
err5
errOAAI
errLeung, Jerry; Strong, Colton; Badior, Katherine E.; Robertson, Madelaine; Wu, Xiaowu; Meledeo, Michael A.; Kang, Emma; Paul, Manoj; Sato, Yusuke; Harashima, Hideyoshi; Cap, Andrew P.; Devine, Dana V.; Jan, Eric; Cullis, Pieter R.; Kastrup, Christian J.
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Research Directions

No research directions
Co-authors
Cooperation Journals
R
Róbert Langer
H-index: 262 · Papers: 2.0K
R
Ralph Weissleder
H-index: 200 · Papers: 1.6K
G
Galen D. Stucky
H-index: 151 · Papers: 1.1K
D
Daniel G. Anderson
H-index: 128 · Papers: 470
M
Matthias Nahrendorf
H-index: 119 · Papers: 465
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