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Modelling the spatial heterogeneity of CD45-positive tumor infiltrating lymphocytes in early-stage, estrogen receptor-positive breast cancer Kinsella, Zak; Blumel, Anna; Lucas, Mairi; Lindner, Andreas; Gonzalez, Claudia A.; Rahman, Arman; Fay, Joanna; O'Grady, Tony; Murphy, Verena; Crown, John; Kelly, Cathy; Gallagher, William; O'Connor, Darran Share Save
Multiplexed Immunofluorescence Imaging Reveals an Immune-Rich Tumor Microenvironment in Mucinous Rectal Cancer Characterized by Increased Lymphocyte Infiltration and Enhanced Programmed Cell Death Protein 1 Expression Duggan, William P.; Kisakol, Batuhan; O'Connell, Emer; Matveeva, Anna; O'Grady, Tony; McDonough, Elizabeth; Lindner, Andreas U.; McNamara, Deborah; Longley, Daniel; Ginty, Fiona; Burke, John P.; Prehn, Jochen H. M. Share Save
Bcl-xL Is a Key Mediator of Apoptosis Following KRASG12C Inhibition in KRASG12C-mutant Colorectal Cancer Khawaja, Hajrah; Briggs, Rebecca; Latimer, Cheryl H.; Rassel, Mustasin; Griffin, Dary; Hanson, Lyndsey; Bardelli, Alberto; Di Nicolantonio, Frederica; McDade, Simon S.; Scott, Christopher J.; Lambe, Shauna; Maurya, Manisha; Lindner, Andreas U.; Prehn, Jochen H. M.; Sousa, Jose; Winnington, Chris; LaBonte, Melissa J.; Ross, Sarah; Van Schaeybroeck, Sandra Share Save
Apoptotic and Necroptotic Mediators are Differentially Expressed in Mucinous and Non-Mucinous Colorectal Cancer O'Connell, Emer; Reynolds, Ian S.; Lindner, Andreas U.; Salvucci, Manuela; O'Grady, Tony; Bacon, Orna; Cho, Sanghee; McDonough, Elizabeth; Longley, Daniel; Ginty, Fiona; McNamara, Deborah A.; Burke, John P.; Prehn, Jochen H. M. Share Save
Stratification of chemotherapy-treated stage III colorectal cancer patients using multiplexed imaging and single-cell analysis of T-cell populations Stachtea, Xanthi; Loughrey, Maurice B.; Salvucci, Manuela; Lindner, Andreas U.; Cho, Sanghee; McDonough, Elizabeth; Sood, Anup; Graf, John; Santamaria-Pang, Alberto; Corwin, Alex; Laurent-Puig, Pierre; Dasgupta, Sonali; Shia, Jinru; Owens, Jonathan R.; Abate, Samantha; Van Schaeybroeck, Sandra; Lawler, Mark; Prehn, Jochen H. M.; Ginty, Fiona; Longley, Daniel B. Share Save
An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution Lindner, Andreas Ulrich; Salvucci, Manuela; McDonough, Elizabeth; Cho, Sanghee; Stachtea, Xanthi; O'Connell, Emer P.; Corwin, Alex D.; Santamaria-Pang, Alberto; Carberry, Steven; Fichtner, Michael; Van Schaeybroeck, Sandra; Laurent-Puig, Pierre; Burke, John P.; McNamara, Deborah A.; Lawler, Mark; Sood, Anup; Graf, John F.; Rehm, Markus; Dunne, Philip D.; Longley, Daniel B.; Ginty, Fiona; Prehn, Jochen H. M. Share Save
Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer Lafferty, Adam; O'Farrell, Alice C.; Migliardi, Giorgia; Khemka, Niraj; Lindner, Andreas U.; Sassi, Francesco; Zanella, Eugenia R.; Salvucci, Manuela; Vanderheyden, Evy; Modave, Elodie; Boeckx, Bram; Halang, Luise; Betge, Johannes; Ebert, Matthias P. A.; Dicker, Patrick; Argiles, Guillem; Tabernero, Josep; Dienstmann, Rodrigo; Medico, Enzo; Lambrechts, Diether; Bertotti, Andrea; Isella, Claudio; Trusolino, Livio; Prehn, Jochen H. M.; Byrne, Annette T. Share Save
Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer Dowling, Catriona M.; Hollinshead, Kate E. R.; Di Grande, Alessandra; Pritchard, Justin; Zhang, Hua; Dillon, Eugene T.; Haley, Kathryn; Papadopoulos, Eleni; Mehta, Anita K.; Bleach, Rachel; Lindner, Andreas U.; Mooney, Brian; Dussmann, Heiko; O'Connor, Darran; Prehn, Jochen H. M.; Wynne, Kieran; Hemann, Michael; Bradner, James E.; Kimmelman, Alec C.; Guerriero, Jennifer L.; Cagney, Gerard; Wong, Kwok-Kin; Letai, Anthony G.; Chonghaile, Triona Ni Share Save
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Systems analysis of protein signatures predicting cetuximab responses in KRAS, NRAS, BRAF and PIK3CA wild-type patient-derived xenograft models of metastatic colorectal cancer Lindner, Andreas U.; Carberry, Steven; Monsefi, Naser; Barat, Ana; Salvucci, Manuela; O'Byrne, Robert; Zanella, Eugenia R.; Cremona, Mattia; Hennessy, Bryan T.; Bertotti, Andrea; Trusolino, Livio; Prehn, Jochen H. M. Share Save
Lower cellular activation of cMET signaling network is associated with reduced recurrence risk in stage II colorectal cancer McDonough, Elizabeth; Sood, Anup; Ginty, Fiona; Cho, Sanghee; Graf, John; Prehn, Jochen; Dunne, Philip; Lindner, Andreas; Salvucci, Manuela; Longley, Daniel; Lawler, Mark; Hollmann, Travis; Shia, Jinru Share Save
DRUG SCREENING OF AVAILABLE ANTI-CANCER DRUGS ON PATIENT-DERIVED GBM CULTURES IDENTIFIES CANDIDATE TREATMENTS FOR A SUBPOPULATION OF GBM PATIENTS Ntafoulis, I.; Kers, T.; van der Kaaij, M.; Balvers, R.; Hayes, J.; van Rij, J.; Tching, R.; Lindner, A.; Prehn, J.; Kremer, A.; Dirven, C.; Leenstra, S.; Lamfers, M. Share Save
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A Stepwise Integrated Approach to Personalized Risk Predictions in Stage III Colorectal Cancer Salvucci, Manuela; Wurstle, Maximilian L.; Morgan, Clare; Curry, Sarah; Cremona, Mattia; Lindner, Andreas U.; Bacon, Orna; Resler, Alexa J.; Murphy, Aine C.; O'Byrne, Robert; Flanagan, Lorna; Dasgupta, Sonali; Rice, Nadege; Pilati, Camilla; Zink, Elisabeth; Scholler, Lisa M.; Toomey, Sinead; Lawler, Mark; Johnston, Patrick G.; Wilson, Richard; Camilleri-Broet, Sophie; Salto-Tellez, Manuel; McNamara, Deborah A.; Kay, Elaine W.; Laurent-Puig, Pierre; Van Schaeybroeck, Sandra; Hennessy, Bryan T.; Longley, Daniel B.; Rehm, Markus; Prehn, Jochen H. M. Share Save
Calnexin, an ER stress-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer (vol 14, 196, 2016) Ryan, Deborah; Carberry, Steven; Murphy, Aine C.; Lindner, Andreas U.; Fay, Joanna; Hector, Suzanne; McCawley, Niamh; Bacon, Orna; Concannon, Caoimhin G.; Kay, Elaine W.; McNamara, Deborah A.; Prehn, Jochen H. M. Share Save
System-based BCL2 family protein signatures as predictive biomarkers in triple-negative breast cancer Lucantoni, Federico; Lindner, Andreas U.; O'Donovan, Norma; Vareslija, Damir; Hudson, Lance; Hill, Arnold D. K.; Kerin, Michael; Dwyer, Roisin; Young, Leonie; Prehn, Jochen H. M. Share Save
Retrospective evaluation of a system model of the BCL2 family of proteins as a predictive and prognostic biomarker for the clinical outcome of stage II-IV colorectal cancer patients Lindner, Andreas U.; Salvucci, Manuela; Cremona, Mattia; Monsefi, Naser; Curry, Sarah; Morgan, Clare; Resler, Alexa; O'Byrne, Robert; Bacon, Orna; Stuehler, Michael; Flanagan, Lorna; Wilson, Richard; Johnston, Patrick G.; Salto-Tellez, Manuel; Camilleri-Broet, Sophie; McNamara, Deborah A.; Hennessy, Bryan T.; Kay, Elaine W.; Laurent-Puig, Pierre; Van Schaeybroeck, Sandra; Prehn, Jochen H. M. Share Save
Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer Ryan, Deborah; Carberry, Steven; Murphy, Aine C.; Lindner, Andreas U.; Fay, Joanna; Hector, Suzanne; McCawley, Niamh; Bacon, Orna; Concannon, Caoimhin G.; Kay, Elaine W.; McNamara, Deborah A.; Prehn, Jochen H. M. Share Save
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