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J

Juan R. Perilla

university of delaware

31H-index
146Paper Count
4.1KCitation Count
Published Papers 62
Publication Date
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A geometric criterion links HIV-1 capsid topography to its biophysical properties and function
errNature Communications
IF15.7
err2026-06-15
err0
errOAAI
errWenhan Li; Craig A. Peeples; Juan S. Rey; Juan R. Perilla; Reidun Twarock
errShare
errSave
Integrase anchors viral RNA to the HIV-1 capsid interior
errNature
IF48.5
err2026-02-01
err0
PREAI
errSinger, Matthew R.; Li, Zhen; Rey, Juan S.; Hope, Joshua; Chenavier, Florian; Cook, Nicola J.; Punch, Emma; Smith, Jamie; Zhou, Zhiyu; Maslen, Sarah; Masino, Laura; Nans, Andrea; Skehel, Mark; Taylor, Ian A.; Zanetti, Giulia; Zhang, Peijun; Perilla, Juan R.; Engelman, Alan N.; Cherepanov, Peter
errShare
errSave
High-resolution analysis of the human T-cell leukemia virus capsid protein reveals insights into immature particle morphology
errNature Communications
IF15.7
err2025-12-11
err0
errOAAI
errWilliam G. Arndt; Alireza Ramezani; Nathaniel Talledge; Guichuan Yu; Huixin Yang; Bo Chen; Juan R. Perilla; Wei Zhang; Louis M. Mansky
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errSave
Transient Occupancy and Pore Dynamics: IP6 Behavior in HIV-1 T=4 Capsids
errJOURNAL OF PHYSICAL CHEMISTRY B
IF2.9
err2025-12-01
err0
PREAI
errMacke, Amanda C.; Xu, Chaoyi; Sudhakar, Sruthi; Perilla, Juan R.
errShare
errSave
Distinct Target Site of Lenacapavir in Immature HIV-1 and Concurrent Binding with the Maturation Inhibitor Bevirimat
errJournal of the American Chemical Society
IF15.6
err2025-11-06
err0
PREAI
errChunxiang Wu; Megan E. Meuser; Juan S. Rey; Hamed Meshkin; Rachel Yang; Swapnil C. Devarkar; Christian Freniere; Jiong Shi; Christopher Aiken; Juan R. Perilla; Yong Xiong
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errSave
The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir (vol 15, pg e00465, 2024)
errMBIO
IF4.7
err2025-11-01
err0
PREAI
errDinh, Tung; Tber, Zahira; Rey, Juan S.; Mengshetti, Seema; Annamalai, Arun S.; Haney, Reed; Briganti, Lorenzo; Amblard, Franck; Fuchs, James R.; Cherepanov, Peter; Kim, Kyungjin; Schinazi, Raymond F.; Perilla, Juan R.; Kim, Baek; Kvaratskhelia, Mamuka
errShare
errSave
Structural basis for HIV-1 capsid adaption to a deficiency in IP6 packaging
errNature Communications
IF15.7
err2025-09-01
err0
errOAAI
errYanan Zhu; Alex B. Kleinpeter; Juan S. Rey; Juan Shen; Yao Shen; Jialu Xu; Nathan Hardenbrook; Long Chen; Anka Lucic; Juan R. Perilla; Eric O. Freed; Peijun Zhang
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errSave
In-cell structure and variability of pyrenoid Rubisco
errNature Communications
IF15.7
err2025-08-20
err0
errOAAI
errNadav Elad; Zhen Hou; Maud Dumoux; Alireza Ramezani; Juan R. Perilla; Peijun Zhang
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errSave
Atomistic simulations of intact virus capsids: A computational challenge worth the scientific payoff
errCurrent Opinion in Structural Biology
IF7
err2025-06-21
err0
errOAAI
errCarolina Pérez-Segura; Juan R. Perilla; Jodi A. Hadden-Perilla
errShare
errSave
The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir
errMBIO
IF4.7
err2024-11-13
err0
errOAAI
errDinh, Tung; Tber, Zahira; Rey, Juan S.; Mengshetti, Seema; Annamalai, Arun S.; Haney, Reed; Briganti, Lorenzo; Amblard, Franck; Fuchs, James R.; Cherepanov, Peter; Kim, Kyungjin; Schinazi, Raymond F.; Perilla, Juan R.; Kim, Baek; Kvaratskhelia, Mamuka
errShare
errSave
Elasticity of the HIV-1 core facilitates nuclear entry and infection
errPLOS PATHOGENS
IF4.9
err2024-09-11
err8
errOAAI
errDeshpande, Akshay; Bryer, Alexander J.; Andino-Moncada, Jonathan R.; Shi, Jiong; Hong, Jun; Torres, Cameron; Harel, Shimon; Francis, Ashwanth C.; Perilla, Juan R.; Aiken, Christopher; Rousso, Itay
errShare
errSave
Computational structural biology: Evolution of the field
errJOURNAL OF STRUCTURAL BIOLOGY
IF5.1
err2024-09-01
err0
PREAI
errHadden-Perilla, Jodi A.; Perilla, Juan R.
errShare
errSave
Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization
errNATURE COMMUNICATIONS
IF15.7
err2023-09-12
err6
errOAAI
errGres, Anna T.; Kirby, Karen A.; Mcfadden, William M.; Du, Haijuan; Liu, Dandan; Xu, Chaoyi; Bryer, Alexander J.; Perilla, Juan R.; Shi, Jiong; Aiken, Christopher; Fu, Xiaofeng; Zhang, Peijun; Francis, Ashwanth C.; Melikyan, Gregory B.; Sarafianos, Stefan G.
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errSave
Molecular architecture and conservation of an immature human endogenous retrovirus
errNATURE COMMUNICATIONS
IF15.7
err2023-08-24
err4
errOAAI
errKrebs, Anna-Sophia; Liu, Hsuan-Fu; Zhou, Ye; Rey, Juan S.; Levintov, Lev; Shen, Juan; Howe, Andrew; Perilla, Juan R.; Bartesaghi, Alberto; Zhang, Peijun
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errSave
Performance efficient macromolecular mechanics via sub-nanometer shape based coarse graining
errNATURE COMMUNICATIONS
IF15.7
err2023-04-10
err5
errOAAI
errBryer, Alexander J.; Rey, Juan S.; Perilla, Juan R.
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errSave
The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-03-21
err16
errOAAI
errShen, Qi; Kumari, Sushila; Xu, Chaoyi; Jang, Sooin; Shi, Jiong; Burdick, Ryan C.; Levintov, Lev; Xiong, Qiancheng; Wu, Chunxiang; Devarkar, Swapnil C.; Tian, Taoran; Tripler, Therese N.; Hu, Yingxia; Yuan, Shuai; Temple, Joshua; Feng, Qingzhou; Lusk, Patrick; Aiken, Christopher; Engelman, Alan N.; Perilla, Juan R.; Pathak, Vinay K.; Lin, Chenxian; Xiong, Yong
errShare
errSave
Structural basis of HIV-1 maturation inhibitor binding and activity
errNATURE COMMUNICATIONS
IF15.7
err2023-03-04
err14
errOAAI
errSarkar, Sucharita; Zadrozny, Kaneil K.; Zadorozhnyi, Roman; Russell, Ryan W.; Quinn, Caitlin M.; Kleinpeter, Alex; Ablan, Sherimay; Meshkin, Hamed; Perilla, Juan R.; Freed, Eric O.; Ganser-Pornillos, Barbie K.; Pornillos, Owen; Gronenborn, Angela M.; Polenova, Tatyana
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errSave
The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function
errMBIO
IF4.7
err2023-02-28
err7
errOAAI
errSinger, Matthew R.; Dinh, Tung; Levintov, Lev; Annamalai, Arun S.; Rey, Juan S.; Briganti, Lorenzo; Cook, Nicola J.; Pye, Valerie E.; Taylor, Ian A.; Kim, Kyungjin; Engelman, Alan N.; Kim, Baek; Perilla, Juan R.; Kvaratskhelia, Mamuka; Cherepanova, Peter
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errSave
Recognition of the TDP-43 nuclear localization signal by importin α1/β
errCELL REPORTS
IF6.9
err2022-06-01
err33
errOAAI
errDoll, Steven G.; Meshkin, Hamed; Bryer, Alexander J.; Li, Fenglin; Ko, Ying-Hui; Lokareddy, Ravi K.; Gillilan, Richard E.; Gupta, Kushol; Perilla, Juan R.; Cingolani, Gino
errShare
errSave
HIV-1 mutants that escape the cytotoxic T-lymphocytes are defective in viral DNA integration
errPNAS NEXUS
IF3.8
err2022-05-20
err7
errOAAI
errBalasubramaniam, Muthukumar; Davids, Benem-Orom; Bryer, Alex; Xu, Chaoyi; Thapa, Santosh; Shi, Jiong; Aiken, Christopher; Pandhare, Jui; Perilla, Juan R.; Dash, Chandravanu
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Research Directions

No research directions
Co-authors
Cooperation Journals
K
Klaus Schulten
H-index: 145 · Papers: 718
A
Angela M. Gronenborn
H-index: 119 · Papers: 797
刘
刘波 (Bo Liu)
H-index: 104 · Papers: 4.5K
M
Michael W. Parker
H-index: 90 · Papers: 805
R
Raymond F. Schinazi
H-index: 87 · Papers: 876
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