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Low-cost generation of clinical-grade , layperson-friendly pharmacogenetic passports using oligonucleotide arrays Lanting, P; Warmerdam, R; Slager, J; Brugge, H; Ochi, T; Benjamins, M; Lopera-Maya, E; Jankipersadsing, S; Gelderloos-Arends, J; Teuben, D; Hendriksen, D; Charbon, B; Johansson, L; Munnink, TO; de Boer-Veger, N; Wilffert, B; Swertz, M; Touw, D; Deelen, P; Knoers, N; Dekens, J; Franke, L Share Save
Identification of rare disease genes as drivers of common diseases through tissue-specific gene regulatory networks Bakker, Olivier B.; Claringbould, Annique; Westra, Harm-Jan; Wiersma, Henry; Boulogne, Floranne; Vosa, Urmo; Urzua-Traslavina, Carlos G.; Symmons, Sophie Mulcahy; Zidan, Mahmoud M. M.; Sadler, Marie C.; Kutalik, Zoltan; Jonkers, Iris H.; Franke, Lude; Deelen, Patrick Share Save
Epigenome-wide association study on the plasma metabolome suggests self-regulation of the glycine and serine pathway through DNA methylation Wu, Jiafei; Palasantzas, Victoria; Andreu-Sanchez, Sergio; Ploesch, Torsten; Leonard, Sam; Li, Shuang; Bonder, Marc Jan; Westra, Harm-Jan; van Meurs, Joyce; Ghanbari, Mohsen; Franke, Lude; Zhernakova, Alexandra; Fu, Jingyuan; Hoogerland, Joanne A.; Zhernakova, Daria V. Share Save
An iPSC-derived small intestine-on-chip with self-organizing epithelial, mesenchymal, and neural cells Moerkens, Renee; Mooiweer, Joram; Ramirez-Sanchez, Aaron D.; Oelen, Roy; Franke, Lude; Wijmenga, Cisca; Barrett, Robert J.; Jonkers, Iris H.; Withoff, Sebo Share Save
Understanding the genetic complexity of puberty timing across the allele frequency spectrum Kentistou, Katherine A.; Kaisinger, Lena R.; Stankovic, Stasa; Vaudel, Marc; de Oliveira, Edson Mendes; Messina, Andrea; Walters, Robin G.; Liu, Xiaoxi; Busch, Alexander S.; Helgason, Hannes; Thompson, Deborah J.; Santoni, Federico; Petricek, Konstantin M.; Zouaghi, Yassine; Huang-Doran, Isabel; Gudbjartsson, Daniel F.; Bratland, Eirik; Lin, Kuang; Gardner, Eugene J.; Zhao, Yajie; Jia, Raina Y.; Terao, Chikashi; Riggan, Marjorie J.; Bolla, Manjeet K.; Yazdanpanah, Mojgan; Yazdanpanah, Nahid; Bradfield, Jonathan P.; Broer, Linda; Campbell, Archie; Chasman, Daniel I.; Cousminer, Diana L.; Franceschini, Nora; Franke, Lude H.; Girotto, Giorgia; He, Chunyan; Jarvelin, Marjo-Riitta; Joshi, Peter K.; Kamatani, Yoichiro; Karlsson, Robert; Luan, Jian'an; Lunetta, Kathryn L.; Magi, Reedik; Mangino, Massimo; Medland, Sarah E.; Meisinger, Christa; Noordam, Raymond; Nutile, Teresa; Concas, Maria Pina; Polasek, Ozren; Porcu, Eleonora; Ring, Susan M.; Sala, Cinzia; Smith, Albert V.; Tanaka, Toshiko; Van der Most, Peter J.; Vitart, Veronique; Wang, Carol A.; Willemsen, Gonneke; Zygmunt, Marek; Ahearn, Thomas U.; Andrulis, Irene L.; Anton-Culver, Hoda; Antoniou, Antonis C.; Auer, Paul L.; Barnes, Catriona L. K.; Beckmann, Matthias W.; de Gonzalez, Amy Berrington; Bogdanova, Natalia V.; Bojesen, Stig E.; Brenner, Hermann; Buring, Julie E.; Canzian, Federico; Chang-Claude, Jenny; Couch, Fergus J.; Cox, Angela; Crisponi, Laura; Czene, Kamila; Daly, Mary B.; Demerath, Ellen W.; Dennis, Joe; Devilee, Peter; De Vivo, Immaculata; Doerk, Thilo; Dunning, Alison M.; Dwek, Miriam; Eriksson, Johan G.; Fasching, Peter A.; Fernandez-Rhodes, Lindsay; Ferreli, Liana; Fletcher, Olivia; Gago-Dominguez, Manuela; Garcia-Closas, Montserrat; Garcia-Saenz, Jose A.; Gonzalez-Neira, Anna; Grallert, Harald; Guenel, Pascal; Haiman, Christopher A.; Hall, Per; Hamann, Ute; Hakonarson, Hakon; Hart, Roger J.; Hickey, Martha; Hooning, Maartje J.; Hoppe, Reiner; Hopper, John L.; Hottenga, Jouke-Jan; Hu, Frank B.; Huebner, Hanna; Hunter, David J.; Jernstrom, Helena; John, Esther M.; Karasik, David; Khusnutdinova, Elza K.; Kristensen, Vessela N.; Lacey, James V.; Lambrechts, Diether; Launer, Lenore J.; Lind, Penelope A.; Lindblom, Annika; Magnusson, Patrik K. E.; Mannermaa, Arto; McCarthy, Mark I.; Meitinger, Thomas; Menni, Cristina; Michailidou, Kyriaki; Millwood, Iona Y.; Milne, Roger L.; Montgomery, Grant W.; Nevanlinna, Heli; Nolte, Ilja M.; Nyholt, Dale R.; Obi, Nadia; O'Brien, Katie M.; Offit, Kenneth; Oldehinkel, Albertine J.; Ostrowski, Sisse R.; Palotie, Aarno; Pedersen, Ole B.; Peters, Annette; Pianigiani, Giulia; Plaseska-Karanfilska, Dijana; Pouta, Anneli; Pozarickij, Alfred; Radice, Paolo; Rennert, Gad; Rosendaal, Frits R.; Ruggiero, Daniela; Saloustros, Emmanouil; Sandler, Dale P.; Schipf, Sabine; Schmidt, Carsten O.; Schmidt, Marjanka K.; Small, Kerrin; Spedicati, Beatrice; Stampfer, Meir; Stone, Jennifer; Tamimi, Rulla M.; Teras, Lauren R.; Tikkanen, Emmi; Turman, Constance; Vachon, Celine M.; Wang, Qin; Winqvist, Robert; Wolk, Alicja; Zemel, Babette S.; Zheng, Wei; van Dijk, Ko W.; Alizadeh, Behrooz Z.; Bandinelli, Stefania; Boerwinkle, Eric; Boomsma, Dorret I.; Ciullo, Marina; Chenevix-Trench, Georgia; Cucca, Francesco; Esko, Tonu; Gieger, Christian; Grant, Struan F. A.; Gudnason, Vilmundur; Hayward, Caroline; Kolcic, Ivana; Kraft, Peter; Lawlor, Deborah A.; Martin, Nicholas G.; Nohr, Ellen A.; Pedersen, Nancy L.; Pennell, Craig E.; Ridker, Paul M.; Robino, Antonietta; Snieder, Harold; Sovio, Ulla; Spector, Tim D.; Stockl, Doris; Sudlow, Cathie; Timpson, Nic J.; Toniolo, Daniela; Uitterlinden, Andre; Ulivi, Sheila; Volzke, Henry; Wareham, Nicholas J.; Widen, Elisabeth; Wilson, James F.; Pharoah, Paul D. P.; Li, Liming; Easton, Douglas F.; Njolstad, Pal R.; Sulem, Patrick; Murabito, Joanne M.; Murray, Anna; Manousaki, Despoina; Juul, Anders; Erikstrup, Christian; Stefansson, Kari; Horikoshi, Momoko; Chen, Zhengming; Farooqi, I. Sadaf; Pitteloud, Nelly; Johansson, Stefan; Day, Felix R.; Perry, John R. B.; Ong, Ken K. Share Save
Single-Cell Dissection of the Immune Response After Acute Myocardial Infarction van Blokland, Irene V.; Oelen, Roy; Groot, Hilde E.; Benjamins, Jan Walter; Pekayvaz, Kami; Losert, Corinna; Knottenberg, Viktoria; Heinig, Matthias; Nicolai, Leo; Stark, Konstantin; van der Harst, Pim; Franke, Lude; van der Wijst, Monique G. P. Share Save
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes Pekayvaz, Kami; Losert, Corinna; Knottenberg, Viktoria; Gold, Christoph; van Blokland, Irene V.; Oelen, Roy; Groot, Hilde E.; Benjamins, Jan Walter; Brambs, Sophia; Kaiser, Rainer; Gottschlich, Adrian; Hoffmann, Gordon Victor; Eivers, Luke; Martinez-Navarro, Alejandro; Bruns, Nils; Stiller, Susanne; Akgoel, Sezer; Yue, Keyang; Polewka, Vivien; Escaig, Raphael; Joppich, Markus; Janjic, Aleksandar; Popp, Oliver; Kobold, Sebastian; Petzold, Tobias; Zimmer, Ralf; Enard, Wolfgang; Saar, Kathrin; Mertins, Philipp; Huebner, Norbert; van der Harst, Pim; Franke, Lude H.; van der Wijst, Monique G. P.; Massberg, Steffen; Heinig, Matthias; Nicolai, Leo; Stark, Konstantin Share Save
Demuxafy: improvement in droplet assignment by integrating multiple single-cell demultiplexing and doublet detection methods Neavin, Drew; Senabouth, Anne; Arora, Himanshi; Lee, Jimmy Tsz Hang; Ripoll-Cladellas, Aida; Franke, Lude; Prabhakar, Shyam; Ye, Chun Jimmie; McCarthy, Davis J.; Mele, Marta; Hemberg, Martin; Powell, Joseph E. Share Save
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PICALO: principal interaction component analysis for the identification of discrete technical, cell-type, and environmental factors that mediate eQTLs Vochteloo, Martijn; Deelen, Patrick; Vink, Britt; Tsai, Ellen A.; Runz, Heiko; Andreu-Sanchez, Sergio; Fu, Jingyuan; Zhernakova, Alexandra; Westra, Harm-Jan; Franke, Lude Share Save
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Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data Li, Shuang; Schmid, Katharina T.; de Vries, Dylan H.; Korshevniuk, Maryna; Losert, Corinna; Oelen, Roy; van Blokland, Irene, V; Groot, Hilde E.; Swertz, Morris A.; van der Harst, Pim; Westra, Harm-Jan; van der Wijst, Monique G. P.; Heinig, Matthias; Franke, Lude Share Save
OTTERS: a powerful TWAS framework leveraging summary-level reference data Dai, Qile; Zhou, Geyu; Zhao, Hongyu; Vosa, Urmo; Franke, Lude; Battle, Alexis; Teumer, Alexander; Lehtimaki, Terho; Raitakari, Olli T.; Esko, Tonu; Epstein, Michael P.; Yang, Jingjing Share Save
Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases de Klein, Niek; Tsai, Ellen A.; Vochteloo, Martijn; Baird, Denis; Huang, Yunfeng; Chen, Chia-Yen; van Dam, Sipko; Oelen, Roy; Deelen, Patrick; Bakker, Olivier B.; El Garwany, Omar; Ouyang, Zhengyu; Marshall, Eric E.; Zavodszky, Maria I.; van Rheenen, Wouter; Bakker, Mark K.; Veldink, Jan; Gaunt, Tom R.; Runz, Heiko; Franke, Lude; Westra, Harm-Jan Share Save
KidneyNetwork: using kidney-derived gene expression data to predict and prioritize novel genes involved in kidney disease Boulogne, Floranne; Claus, Laura R.; Wiersma, Henry; Oelen, Roy; Schukking, Floor; de Klein, Niek; Li, Shuang; Westra, Harm-Jan; van der Zwaag, Bert; van Reekum, Franka; Sierks, Dana; Schoenauer, Ria; Li, Zhigui; Bijlsma, Emilia K.; Bos, Willem Jan W.; Halbritter, Jan; Knoers, Nine V. A. M.; Besse, Whitney; Deelen, Patrick; Franke, Lude; van Eerde, Albertien M. Share Save
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