Not logged in Share Save
Share Save
Share Save
Towards engineering heart tissues from bioprinted cardiac spheroids Polonchuk, Liudmila; Surija, Lydia; Lee, Min Ho; Sharma, Poonam; Ming, Clara Liu Chung; Richter, Florian; Ben-Sefer, Eitan; Rad, Maryam Alsadat; Sarmast, Hadi Mahmodi Sheikh; Al Shamery, Wafa; Tran, Hien A.; Vettori, Laura; Haeusermann, Fabian; Filipe, Elysse C.; Rnjak-Kovacina, Jelena; Cox, Thomas; Tipper, Joanne; Kabakova, Irina; Gentile, Carmine Share Save
Use of Patient Health Records to Quantify Drug-Related Pro-arrhythmic Risk Davies, Mark R.; Martinec, Michael; Walls, Robert; Schwarz, Roman; Mirams, Gary R.; Wang, Ken; Steiner, Guido; Surinach, Andy; Flores, Carlos; Lave, Thierry; Singer, Thomas; Polonchuk, Liudmila Share Save
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells (vol 10, 5627, 2020) Kramer, James; Himmel, Herbert M.; Lindqvist, Anders; Stoelzle-Feix, Sonja; Chaudhary, Khuram W.; Li, Dingzhou; Bohme, Georg Andrees; Bridgland-Taylor, Matthew; Hebeisen, Simon; Fan, Jingsong; Renganathan, Muthukrishnan; Imredy, John; Humphries, Edward S. A.; Brinkwirth, Nina; Strassmaier, Tim; Ohtsuki, Atsushi; Danker, Timm; Vanoye, Carlos; Polonchuk, Liudmila; Fermini, Bernard; Pierson, Jennifer Beck; Gintant, Gary Share Save
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm Ridder, Bradley J.; Leishman, Derek J.; Bridgland-Taylor, Matthew; Samieegohar, Mohammadreza; Han, Xiaomei; Wu, Wendy W.; Randolph, Aaron; Phu Tran; Sheng, Jiansong; Danker, Timm; Lindqvist, Anders; Konrad, Daniel; Hebeisen, Simon; Polonchuk, Liudmila; Gissinger, Evgenia; Renganathan, Muthukrishnan; Koci, Bryan; Wei, Haiyang; Fan, Jingsong; Levesque, Paul; Kwagh, Jae; Imredy, John; Zhai, Jin; Rogers, Marc; Humphries, Edward; Kirby, Robert; Stoelzle-Feix, Sonja; Brinkwirth, Nina; Rotordam, Maria Giustina; Becker, Nadine; Friis, Soren; Rapedius, Markus; Goetze, Tom A.; Strassmaier, Tim; Okeyo, George; Kramer, James; Kuryshev, Yuri; Wu, Caiyun; Himmel, Herbert; Mirams, Gary R.; Strauss, David G.; Bardenet, Remi; Li, Zhihua Share Save
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm (vol 394C, 114961, 2020) Ridder, Bradley J.; Leishman, Derek J.; Bridgland-Taylor, Matthew; Samieegohar, Mohammadreza; Han, Xiaomei; Wu, Wendy W.; Randolph, Aaron; Tran, Phu; Sheng, Jiansong; Danker, Timm; Lindqvist, Anders; Konrad, Daniel; Hebeisen, Simon; Polonchuk, Liudmila; Gissinger, Evgenia; Renganathan, Muthukrishnan; Koci, Bryan; Wei, Haiyang; Fan, Jingsong; Levesque, Paul; Kwagh, Jae; Imredy, John; Zhai, Jin; Rogers, Marc; Humphries, Edward; Kirby, Robert; Stoelzle-Feix, Sonja; Brinkwirth, Nina; Rotordam, Maria Giustina; Becker, Nadine; Friis, Soren; Rapedius, Markus; Goetze, Tom A.; Strassmaier, Tim; Okeyo, George; Kramer, James; Kuryshev, Yuri; Wu, Caiyun; Himmel, Herbert; Mirams, Gary R.; Strauss, David G.; Bardenet, Remi; Li, Zhihua Share Save
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells Kramer, James; Himmel, Herbert M.; Lindqvist, Anders; Stoelzle-Feix, Sonja; Chaudhary, Khuram W.; Li, Dingzhou; Bohme, Georg Andrees; Bridgland-Taylor, Matthew; Hebeisen, Simon; Fan, Jingsong; Renganathan, Muthukrishnan; Imredy, John; Humphries, Edward S. A.; Brinkwirth, Nina; Strassmaier, Tim; Ohtsuki, Atsushi; Danker, Timm; Vanoye, Carlos; Polonchuk, Liudmila; Fermini, Bernard; Pierson, Jennifer Beck; Gintant, Gary Share Save
Share Save
Share Save
General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy Li, Zhihua; Mirams, Gary R.; Yoshinaga, Takashi; Ridder, Bradley J.; Han, Xiaomei; Chen, Janell E.; Stockbridge, Norman L.; Wisialowski, Todd A.; Damiano, Bruce; Severi, Stefano; Morissette, Pierre; Kowey, Peter R.; Holbrook, Mark; Smith, Godfrey; Rasmusson, Randall L.; Liu, Michael; Song, Zhen; Qu, Zhilin; Leishman, Derek J.; Steidl-Nichols, Jill; Rodriguez, Blanca; Bueno-Orovio, Alfonso; Zhou, Xin; Passini, Elisa; Edwards, Andrew G.; Morotti, Stefano; Ni, Haibo; Grandi, Eleonora; Clancy, Colleen E.; Vandenberg, Jamie; Hill, Adam; Nakamura, Mikiko; Singer, Thomas; Polonchuk, Liudmila; Greiter-Wilke, Andrea; Wang, Ken; Nave, Stephane; Fullerton, Aaron; Sobie, Eric A.; Paci, Michelangelo; Tshinanu, Flora Musuamba; Strauss, David G. Share Save
Tailoring Mathematical Models to Stem-Cell Derived Cardiomyocyte Lines Can Improve Predictions of Drug-Induced Changes to Their Electrophysiology Lei, Chon Lok; Wang, Ken; Clerx, Michael; Johnstone, Ross H.; Hortigon-Vinagre, Maria P.; Zamora, Victor; Allan, Andrew; Smith, Godfrey L.; Gavaghan, David J.; Mirams, Gary R.; Polonchuk, Liudmila Share Save
Share Save
Share Save
Share Save
Recent developments in using mechanistic cardiac modelling for drug safety evaluation Davies, Mark R.; Wang, Ken; Mirams, Gary R.; Caruso, Antonello; Noble, Denis; Walz, Antje; Lave, Thierry; Schuler, Franz; Singer, Thomas; Polonchuk, Liudmila Share Save
Share Save
Simulation of L-Type Calcium Currents using Different Experimental Data Sources: from Cell Line to iPS-Derived Cardiomyocyte Wang, Ken; Mirams, Gary; Davies, Mark; Caruso, Antonello; Noble, Denis; Alvarez-Sanchez, Ruben; Walz, Antje Christine; Lave, Thierry; Schuler, Franz; Singer, Thomas; Polonchuk, Liudmila Share Save
Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression Lindemann, Lothar; Porter, Richard H.; Scharf, Sebastian H.; Kuennecke, Basil; Bruns, Andreas; von Kienlin, Markus; Harrison, Anthony C.; Paehler, Axel; Funk, Christoph; Gloge, Andreas; Schneider, Manfred; Parrott, Neil J.; Polonchuk, Liudmila; Niederhauser, Urs; Morairty, Stephen R.; Kilduff, Thomas S.; Vieira, Eric; Kolczewski, Sabine; Wichmann, Juergen; Hartung, Thomas; Honer, Michael; Borroni, Edilio; Moreau, Jean-Luc; Prinssen, Eric; Spooren, Will; Wettstein, Joseph G.; Jaeschke, Georg Share Save
.png){kind=icon}
.png){kind=icon}
Not logged in.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
