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Leah C. Byrne

university of pittsburgh

22H-index
88Paper Count
2.9KCitation Count
Published Papers 25
Publication Date
Synthesis and characterization of an injectable telechelic material for the epiretinal delivery of retinal gene therapies
err2026-04-17
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errOAAI
errJames H. Westbay; Daniel P. Bigley; Sushma Sappa; Anfisa Ayalon; Hamzah Aweidah; Lauren D. Dignam; Joseph N. Martel; William A. Beltran; José-Alain Sahel; Leah C. Byrne; Morgan V. DiLeo
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Quantifying functional vision in a mouse model of oculocutaneous albinism type 1
err2026-03-23
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errOAAI
errWyatt G Kriebel; Alessandra M Larimer-Picciani; Mahija Nukala; José-Alain Sahel; Leah C Byrne
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A mobile system for whole eye perfusion supporting retinal function and surgery
err2026-01-16
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errOAAI
errMaxwell Lohss ‡; Katelin S. Samski ‡; Alkiviades Liasis †; Hamzah Aweidah; Chiaki Komatsu; Oliver Beale; Daniel M. W. Lee; Ethan A. Rossi; Sanjeev G. Shroff; José A. Sahel; S. Tonya Stefko; Leah C. Byrne
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Novel photoreceptor-specific promoters for gene therapy in mid- to late-stage retinal degeneration
err2025-05-21
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PREAI
errRaghavi Sudharsan; Leonardo Murgiano; Aditi Ahuja; Yu Sato; Jennifer Kwok; Natalia Dolgova; Svetlana Savina; Morgan Sedorovitz; Valerie L. Dufour; Gustavo D. Aguirre; Leah C. Byrne; William A. Beltran
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Tppp3 is a novel molecule for retinal ganglion cell identification and optic nerve regeneration
err2024-12-29
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errOAAI
errRao, Mishal; Luo, Ziming; Liu, Chia-Chun; Chen, Chi-Yu; Wang, Shining; Nahmou, Michael; Tanasa, Bogdan; Virmani, Aman; Byrne, Leah; Goldberg, Jeffrey L.; Sahel, Jose-Alain; Chang, Kun-Che
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Developing New Vectors for Retinal Gene Therapy
err2023-03-27
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errOAAI
errZin, Emilia A.; Ozturk, Bilge E.; Dalkara, Deniz; Byrne, Leah C.
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Gene augmentation prevents retinal degeneration in a CRISPR/Cas9-based mouse model of PRPF31 retinitis pigmentosa
err2022-12-13
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errOAAI
errXi, Zhouhuan; Vats, Abhishek; Sahel, Jose-Alain; Chen, Yuanyuan; Byrne, Leah C.
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Modeling PRPF31 retinitis pigmentosa using retinal pigment epithelium and organoids combined with gene augmentation rescue
err2022-08-16
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errOAAI
errRodrigues, Amelie; Slembrouck-Brec, Amelie; Nanteau, Celine; Terray, Angelique; Tymoshenko, Yelyzaveta; Zagar, Yvrick; Reichman, Sacha; Xi, Zhouhuan; Sahel, Jose-Alain; Fouquet, Stephane; Orieux, Gael; Nandrot, Emeline F.; Byrne, Leah C.; Audo, Isabelle; Roger, Jerome E.; Goureau, Olivier
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Machine learning sequence prioritization for cell type-specific enhancer design
err2022-05-16
err7
errOAAI
errLawler, Alyssa J.; Ramamurthy, Easwaran; Brown, Ashley R.; Shin, Naomi; Kim, Yeonju; Toong, Noelle; Kaplow, Irene M.; Wirthlin, Morgan; Zhang, Xiaoyu; Phan, BaDoi N.; Fox, Grant A.; Wade, Kirsten; He, Jing; Ozturk, Bilge Esin; Byrne, Leah C.; Stauffer, William R.; Fish, Kenneth N.; Pfenning, Andreas R.
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Targeting ON-bipolar cells by AAV gene therapy stably reverses LRIT3-congenital stationary night blindness
err2022-03-22
err15
errOAAI
errMiyadera, Keiko; Santana, Evelyn; Roszak, Karolina; Iffrig, Sommer; Visel, Meike; Iwabe, Simone; Boyd, Ryan F.; Bartoe, Joshua T.; Sato, Yu; Gray, Alexa; Ripolles-Garcia, Ana; Dufour, Valerie L.; Byrne, Leah C.; Flannery, John G.; Beltran, William A.; Aguirre, Gustavo D.
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Transcriptional and anatomical diversity of medium spiny neurons in the primate striatum
err2021-12-01
err41
errOAAI
errHe, Jing; Kleyman, Michael; Chen, Jianjiao; Alikaya, Aydin; Rothenhoefer, Kathryn M.; Ozturk, Bilge Esin; Wirthlin, Morgan; Bostan, Andreea C.; Fish, Kenneth; Byrne, Leah C.; Pfenning, Andreas R.; Stauffer, William R.
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scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution
err2021-10-19
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PREAI
errOzturk, Bilge E.; Johnson, Molly E.; Kleyman, Michael; Turunc, Serhan; He, Jing; Jabalameli, Sara; Xi, Zhouhuan; Visel, Meike; Dufour, Valerie L.; Iwabe, Simone; Marinho, Luis Felipe L. Pompeo; Aguirre, Gustavo D.; Sahel, Jose-Alain; Schaffer, David, V; Pfenning, Andreas R.; Flannery, John G.; Beltran, William A.; Stauffer, William R.; Byrne, Leah C.
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Parallel functional testing identifies enhancers active in early postnatal mouse brain
err2021-10-04
err21
PREAI
errLambert, Jason T.; Su-Feher, Linda; Cichewicz, Karol; Warren, Tracy L.; Zdilar, Iva; Wang, Yurong; Lim, Kenneth J.; Haigh, Jessica L.; Morse, Sarah J.; Canales, Cesar P.; Stradleigh, Tyler W.; Palacios, Erika Castillo; Haghani, Viktoria; Moss, Spencer D.; Parolini, Hannah; Quintero, Diana; Shrestha, Diwash; Vogt, Daniel; Byrne, Leah C.; Nord, Alex S.
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Pharmacological clearance of misfolded rhodopsin for the treatment ofRHO-associated retinitis pigmentosa
err2020-06-14
err15
errOAAI
errLiu, Xujie; Feng, Bing; Vats, Abhishek; Tang, Hong; Seibel, William; Swaroop, Manju; Tawa, Gregory; Zheng, Wei; Byrne, Leah; Schurdak, Mark; Chen, Yuanyuan
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In vivo directed evolution of adeno-associated virus in the primate retina
err2020-05-21
err78
errOAAI
errByrne, Leah C.; Day, Timothy P.; Visel, Meike; Strazzeri, Jennifer A.; Fortuny, Cecile; Dalkara, Deniz; Merigan, William H.; Schaffer, David, V; Flannery, John G.
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In vivo genome editing improves motor function and extends survival in a mouse model of ALS
err2017-12-01
err147
errOAAI
errGaj, Thomas; Ojala, David S.; Ekman, Freja K.; Byrne, Leah C.; Limsirichai, Prajit; Schaffer, David V.
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Identification of Novel AAV Capsid Variants with Enhanced Tropism for the Canine Outer Retina Following Intravitreal Delivery
err2016-05-01
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errOAAI
errByrne, Leah C.; Visel, Meike; Dufour, Valerie; Marinho, Felipe Pompeo; Aguirre, Gustavo D.; Beltran, William A.; Flannery, John G.; Schaffer, David V.
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Massively parallel cis-regulatory analysis in the mammalian central nervous system
err2015-11-17
err102
errOAAI
errShen, Susan Q.; Myers, Connie A.; Hughes, Andrew E. O.; Byrne, Leah C.; Flannery, John G.; Corbo, Joseph C.
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The Expression Pattern of Systemically Injected AAV9 in the Developing Mouse Retina Is Determined by Age
err2015-02-01
err33
errOAAI
errByrne, Leah C.; Lin, Yvonne J.; Lee, Trevor; Schaffert, David V.; Flannery, John G.
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CRALBP supports the mammalian retinal visual cycle and cone vision
err2015-01-20
err99
errOAAI
errXue, Yunlu; Shen, Susan Q.; Jui, Jonathan; Rupp, Alan C.; Byrne, Leah C.; Hattar, Samer; Flannery, John G.; Corbo, Joseph C.; Kefalov, Vladimir J.
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