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Alexander S. Mosig

Jena University Hospital

32H-index
127Paper Count
3.6KCitation Count
Published Papers 57
Publication Date
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Epigenetic modulation of stromal cell states underpins pathological tissue niches in Crohn’s disease
errNature Immunology
IF27.6
err2026-08-12
err0
errOAAI
errSimon Koplev; Osheen Sharma; Simon Woelfel; Ni Huang; Mathilde Pohin; Adrian Feile; Maria Warschinke; Mikel Rezola Artero; Sharujan Suthakaran; Ioannis Sarropoulos; J. Patrick Pett; Julia Nyman; Tom Thomas; Duy Pham; Bin Li; Moustafa Attar; Julia Pakpoor; Kate Milosevic-Hutton; Alistair Easton; Matt Butler; James Dunford; Martin Philpott; Mark Coles; Christopher D. Buckley; Calliope Dendrou; Khalid Shamiyah; Lorenz Kretschmer; Lisa Dratva; Fadi Issa; Joanna Hester; Jens Rittscher; Alissa Walsh; Simon P. Travis; Fränze Progatzky; Lukas W. Unger; Mark Bignell; Katherine Baker; Bruce George; Hussein Al-Mossawi; Paul Klenerman; Alexander S. Mosig; Udo Oppermann; Sarah A. Teichmann; Fiona M. Powrie; Matthias Friedrich
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Assessing the proinflammatory potential of sterile fecal microbiome filtrate from ulcerative colitis patients using an intestine-on-chip platform and automated image analysis
errGut Microbes
IF11
err2026-07-28
err0
errOAAI
errTobias Schaal; Parastoo Akbarimoghaddam; Valentin D. Wegner; Arndt Steube; Elena Gardey; Adrian Feile; Mohamed I. Abdelwahab Hassan; Zoltán Cseresnyés; Andreas Stallmach; Alexander S. Mosig; Marc Thilo Figge; Johannes Stallhofer
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Human Colitis-on-Chip Model Reveals Dual Roles of Butyrate in Epithelial and Macrophage Defense Against Candida albicans Tissue Invasion
errSmall
IF12.1
err2026-05-01
err0
errOAAI
errAllwang, Manuel; Wipplinger, Maximilian; Akbarimoghaddam, Parastoo; Alonso-Roman, Raquel; Cseresnyes, Zoltan; Dietschmann, Axel; Wegner, Valentin; Feile, Adrian; Bachelot, Yann; Warschinke, Maria; Hassan, Mohamed I. Abdelwahab; Mittag, Sonnhild; Huber, Otmar; Hube, Bernhard; Gresnigt, Mark S.; Figge, Marc Thilo; Mosig, Alexander S.
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Modeling Clostridioides difficile toxin pathogenesis and antiserum protection in an immunocompetent intestine-on-chip platform
errScientific Reports
IF3.9
err2026-03-17
err0
errOAAI
errValentin D. Wegner; Maria Warschinke; Ibtissem Ben Brahim; Adrian Feile; Karen E. Huber; Alexander S. Mosig
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errSave
Staphylococcus aureus biofilm-associated component PNAG stimulates the secretion of the immunomodulatory chemokine CXCL10 via Dectin-1 signaling
errCommunications Biology
IF5.1
err2025-07-31
err0
errOAAI
errReza Gheitasi; Daniel Weiss; Mario M. Müller; Karolin Sommer; Daniela Röll; Alexander Mosig; Mathias. W. Pletz; Oliwia Makarewicz
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Short-Chain Fatty Acids Modulate Anti-ROR1 CAR T-Cell Function and Exhaustion in an Intestinal Adenocarcinoma-on-Chip Model
errADVANCED HEALTHCARE MATERIALS
IF9.6
err2025-04-18
err0
errOAAI
errWegner, VD; Feile, A; Alb, M; Hudecek, M; Hewitt, P; Mosig, AS
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Leveraging Organ-on-Chip Models to Investigate Host-Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease
errADVANCED HEALTHCARE MATERIALS
IF9.6
err2024-11-03
err0
errOAAI
errKaden, Tim; Alonso-Roman, Raquel; Stallhofer, Johannes; Gresnigt, Mark S.; Hube, Bernhard; Mosig, Alexander S.
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errSave
Dissecting Acute Drug-Induced Hepatotoxicity and Therapeutic Responses of Steatotic Liver Disease Using Primary Mouse Liver and Blood Cells in a Liver-On-A-Chip Model
errADVANCED SCIENCE
IF14.1
err2024-06-13
err3
errOAAI
errLiu, Hanyang; Yin, Guo; Kohlhepp, Marlene Sophia; Schumacher, Fabian; Hundertmark, Jana; Hassan, Mohamed I. Abdelwahab; Heymann, Felix; Puengel, Tobias; Kleuser, Burkhard; Mosig, Alexander Sandy; Tacke, Frank; Guillot, Adrien
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Modeling of intravenous caspofungin administration using an intestine-on-chip reveals altered Candida albicans microcolonies and pathogenicity
errBIOMATERIALS
IF12.9
err2024-06-01
err2
errOAAI
errKaden, Tim; Alonso-Roman, Raquel; Akbarimoghaddam, Parastoo; Mosig, Alexander S.; Graf, Katja; Raasch, Martin; Hoffmann, Bianca; Figge, Marc T.; Hube, Bernhard; Gresnigt, Mark S.
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errSave
Downregulation of HNF4A enables transcriptomic reprogramming during the hepatic acute-phase response
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-05-16
err2
errOAAI
errEhle, Charlotte; Iyer-Bierhoff, Aishwarya; Wu, Yunchen; Xing, Shaojun; Kiehntopf, Michael; Mosig, Alexander S.; Godmann, Maren; Heinzel, Thorsten
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An Organ-on-Chip Platform for Simulating Drug Metabolism Along the Gut-Liver Axis
errADVANCED HEALTHCARE MATERIALS
IF9.6
err2024-03-15
err8
errOAAI
errLucchetti, Mara; Aina, Kehinde Oluwasegun; Grandmougin, Lea; Jaeger, Christian; Escriva, Pau Perez; Letellier, Elisabeth; Mosig, Alexander S.; Wilmes, Paul
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Quantification of Polystyrene Uptake by Different Cell Lines Using Fluorescence Microscopy and Label-Free Visualization of Intracellular Polystyrene Particles by Raman Microspectroscopic Imaging
errCELLS
IF5.2
err2024-03-05
err4
errOAAI
errRoth, Amelie; Tannert, Astrid; Ziller, Nadja; Eiserloh, Simone; Goehrig, Bianca; Guliev, Rustam R.; Vazquez, Maria Jose Gonzalez; Naumann, Max; Mosig, Alexander S.; Stengel, Sven; Heutelbeck, Astrid R. R.; Neugebauer, Ute
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Self-Degrading Multifunctional PEG-Based Hydrogels-Tailormade Substrates for Cell Culture
errMACROMOLECULAR BIOSCIENCE
IF4.1
err2024-01-02
err3
errOAAI
errKowalczuk, Kathrin; Dasgupta, Anindita; Paez Larios, Francisco; Ulrich, Hans F.; Wegner, Valentin; Brendel, Johannes C.; Eggeling, Christian; Mosig, Alexander S.; Schacher, Felix H.
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Asymmetric Block Extension of Star-Shaped [PEG-SH]4 - toward Poly(dehydroalanine)-Functionalized PEG Hydrogels for Catch and Release of Charged Guest Molecules
errMACROMOLECULAR BIOSCIENCE
IF4.1
err2023-09-14
err4
errOAAI
errKowalczuk, Kathrin; Mons, Peter J.; Ulrich, Hans F.; Wegner, Valentin D.; Brendel, Johannes C.; Mosig, Alexander S.; Schacher, Felix H.
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errSave
Evaluation of drug-induced liver toxicity of trovafloxacin and levofloxacin in a human microphysiological liver model
errSCIENTIFIC REPORTS
IF3.9
err2023-08-16
err6
errOAAI
errKaden, Tim; Graf, Katja; Rennert, Knut; Li, Ruoya; Mosig, Alexander S. S.; Raasch, Martin
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Human macrophage polarization determines bacterial persistence of Staphylococcus aureus in a liver-on-chip-based infection model
errBIOMATERIALS
IF12.9
err2022-08-01
err18
errOAAI
errSiwczak, Fatina; Cseresnyes, Zoltan; Hassan, Mohamed I. Abdelwahab; Aina, Kehinde Oluwasegun; Carlstedt, Swen; Sigmund, Anke; Groger, Marko; Surewaard, Bas G. J.; Werz, Oliver; Figge, Marc Thilo; Tuchscherr, Lorena; Loffler, Bettina; Mosig, Alexander S.
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The natural compound atraric acid suppresses androgen-regulated neo-angiogenesis of castration-resistant prostate cancer through angiopoietin 2
errONCOGENE
IF7.3
err2022-05-05
err13
errOAAI
errEhsani, Marzieh; Bartsch, Sophie; Rasa, Seyed Mohammad Mahdi; Dittmann, Jessica; Pungsrinont, Thanakorn; Neubert, Laura; Huettner, Soeren S.; Kotolloshi, Roland; Schindler, Katrin; Ahmad, Aya; Mosig, Alexander S.; Adam, Lisa; Ori, Alessandro; Neri, Francesco; Berndt, Alexander; Grimm, Marc-Oliver; Baniahmad, Aria
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Invasive aspergillosis-on-chip: A quantitative treatment study of human Aspergillus fumigatus infection
errBIOMATERIALS
IF12.9
err2022-04-01
err14
errOAAI
errHoang, T. N. M.; Cseresnyes, Z.; Hartung, S.; Blickensdorf, M.; Saffer, C.; Rennert, K.; Mosig, A. S.; von Lilienfeld-Toal, M.; Figge, M. T.
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Intestinal Stem Cell-on-Chip to Study Human Host-Microbiota Interaction
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2021-12-06
err28
errOAAI
errSiwczak, Fatina; Loffet, Elise; Kaminska, Mathilda; Koceva, Hristina; Mahe, Maxime M.; Mosig, Alexander S.
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Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-07-19
err12
errOAAI
errNeukirch, Konstantin; Alsabil, Khaled; Dinh, Chau-Phi; Bilancia, Rossella; Raasch, Martin; Ville, Alexia; Cerqua, Ida; Viault, Guillaume; Breard, Dimitri; Pace, Simona; Temml, Veronika; Brunner, Elena; Jordan, Paul M.; Marques, Marta C.; Loeser, Konstantin; Gollowitzer, Andre; Permann, Stephan; Gerstmeier, Jana; Lorkowski, Stefan; Stuppner, Hermann; Garscha, Ulrike; Rodrigues, Tiago; Bernardes, Goncalo J. L.; Schuster, Daniela; Seraphin, Denis; Richomme, Pascal; Rossi, Antonietta; Mosig, Alexander S.; Roviezzo, Fiorentina; Werz, Oliver; Helesbeux, Jean-Jacques; Koeberle, Andreas
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Research Directions

The data has not been retrieved yet.
Co-authors
Cooperation Journals
S
Sarah A. Teichmann
H-index: 141 · Papers: 679
U
Ulrich S. Schubert
H-index: 138 · Papers: 2.3K
P
Paul Klenerman
H-index: 137 · Papers: 1.2K
F
Frank Tacke
H-index: 124 · Papers: 1.4K
V
Vasilis Ntziachristos
H-index: 110 · Papers: 1.1K
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