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J

Jörg H. W. Distler

Heinrich Heine University

95H-index
560Paper Count
4.2WCitation Count
Published Papers 237
Publication Date
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Inflammation reprograms fibro-adipogenic progenitors to sustain immunopathogenic niches in myositis
errCell Death & Disease
IF9.6
err2026-06-12
err0
errOAAI
errChristopher Nelke; Julian Sanchez-Dal Cin; Charles-Antoine Dallevet; Jin-Soo Park; Jacqueline C. Kinold; Christina B. Schroeter; Felix Kleefeld; Anne-Katrin Güttsches; Paula Quint; Sara Walli; Derya Cengiz; Vera Dobelmann; Corinna Preusse; Alexander Mensch; Anne Schänzer; Markus Leo; Tim Hagenacker; Benedikt Schoser; Jörg H. W. Distler; Akiyoshi Uezumi; Werner Stenzel; Sven G. Meuth; Olivier Benveniste; Yves Allenbach; Tobias Ruck
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The nuclear receptor TR4 orchestrates cytoskeletal organization in a Gα12/ROCK-dependent manner to promote myofibroblast differentiation and tissue fibrosis in systemic sclerosis
errArthritis & Rheumatology
IF10.9
err2026-05-28
err0
errOAAI
errYun Zhang PHD; Lichong Shen MD; Junhui Zheng MSc; Gisela Baur MD; Dilidaer Yasen MSc; Honglin Zhu MD; Yi-Nan Li PHD; Xianyi Meng PHD; Thuong Trinh-Minh PHD; Tim Filla PHD; Debomita Chakraborty PHD; Andrea-Hermina Györfi MD; Christina Bergmann MD; Adam Reich MD, PHD; Alexander Kreuter MD; Georg Schett MD; Jörg H. W. Distler MD
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Deep phenotyping of skin tissue remodeling in patients with systemic sclerosis treated with CD19-CAR T cells
errNature Communications
IF15.7
err2026-05-23
err0
errOAAI
errAleix Rius Rigau; Meilin Xu; Ziyuan Liu; Sara Chenguiti Fakhouri; Janina Auth; Panagiotis Garantziotis; Andrea Zoli; Manoj Kumar Selvaraju; Maria Gabriella Raimondo; Carlo Tur; Tim Filla; Paula Gehringer; Markus Eckstein; Fabian Müller; Armin Atzinger; Moritz Ronicke; Arif Ekici; Rafael Schmid; Andreas Wirsching; Melanie Hagen; Sebastian Böltz; Tobias Krickau; Raymund E. Horch; Carola Berking; Ricardo Grieshaber-Bouyer; Andreas Ramming; Pooja Gupta; Aline Bozec; Andreas Mackensen; Jörg HW Distler; Georg Schett; Yi-Nan Li; Christina Bergmann
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Low-energy small language models with retrieval-augmented generation can surpass large-model performance in rheumatology
errFrontiers in Medicine
IF3
err2026-05-08
err0
errOAAI
errSF Sabine Felde; RB Rüdiger Buchkremer; GC Gamal Chehab; CT Christian Thielscher; JH Jörg H. W. Distler; MS Matthias Schneider; JG Jutta G. Richter
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Reprogramming of stroma-derived chemokine networks drives the loss of tissue organization in nodal B cell lymphoma
errNature Cancer
IF28.5
err2026-03-25
err0
errOAAI
errFelix Czernilofsky; Anna Mathioudaki; Lea Jopp-Saile; Raphael Lutz; Dominik Vonficht; Xi Wang; Christina Schniederjohann; Harald Voehringer; Tobias Roider; Marc-Andrea Baertsch; Claus Rodemer; Henry Löffler-Wirth; Michael Grau; Donnacha Fitzgerald; Johannes Mammen; Jan Kosla; Nora Liebers; Peter-Martin Bruch; Diana Ordoñez-Rueda; Alexander Brobeil; Gunhild Mechtersheimer; Caroline Pabst; Carsten Müller-Tidow; Andreas Trumpp; Marc Seifert; Frank Neumann; Mathias Heikenwälder; Vladimir Benes; Wolfgang Huber; Jörg Distler; Georg Lenz; Hans Binder; Reiner Siebert; Garry P. Nolan; Moritz Gerstung; Judith B. Zaugg; Daniel Hübschmann; Simon Haas; Sascha Dietrich
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Bispecific T cell engagers for treatment-refractory autoimmune connective tissue diseases
errNature Medicine
IF50
err2026-02-19
err0
errOAAI
errChristina Düsing; Andrea-Hermina Györfi; Ayla Nadja Stütz; Laura-Marie Lahu; Franca Sophie Deicher; Yi-Nan Li; Peter-Martin Bruch; Alexandru-Emil Matei; Alexandru Micu; Tim Filla; Sarah Koziel; Alexander Sebastian Hölscher; Manuel Röhrich; Hanns-Martin Lorenz; Mareike Cramer; Gerald Antoch; Jörg Timm; Yousef Abusabha; Tobias Ruck; Bernhard Homey; Alexander Kreuter; Björn Buehring; Aleksandar Radujkovic; Claus Peter Heußel; Melanie Hagen; Ricardo Grieshaber-Bouyer; Georg Schett; Anna Brunn; Sascha Dietrich; Wolfgang Merkt; Jörg H. W. Distler
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Mechanisms of fibrotic tissue remodelling: insights from systemic sclerosis
errNature Reviews Rheumatology
IF32.7
err2026-01-26
err0
PREAI
errJörg H. W. Distler; David Launay; Carol Feghali-Bostwick; Alexandru-Emil Matei; Maria Trojanowska; Johann E. Gudjonsson
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Fcγ-receptor-activation by circulating immune complexes in systemic autoimmune diseases and its reduction by CD19-CAR T cell therapy
errRheumatology
IF4.4
err2025-12-01
err2
PREAI
errFreitag, Merle; Kolb, Philipp; Falcone, Valeria; Claus, Maren; Schroder, Pauline; Andreeva, Ivana; Rodon, Lea; Ewald, Meike; Deicher, Franca Sophie; Stutz, Ayla Nadja; Distler, Jorg H. W.; Blank, Norbert; Grieshaber-Bouyer, Ricardo; Munoz, Luis E.; Lorenz, Hanns-Martin; Schett, Georg; Merkt, Wolfgang
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68Gallium-labelled fibroblast activation protein inhibitor uptake in joints: a single-center cohort analysis of 268 patients
errEuropean Journal of Nuclear Medicine and Molecular Imaging
IF7.6
err2025-11-20
err0
errOAAI
errAnna-Maria Spektor; Antonia van Genabith; Jorge Hoppner; Leon Walkenbach; Thomas Hielscher; Peter Kvacskay; Sarah Richter; Kiangenda Trésor Sungu-Winkler; Hans-Ulrich Kauczor; Hanns-Martin Lorenz; Mathias Schreckenberger; Jörg Distler; Uwe Haberkorn; Wolfgang Merkt; Manuel Röhrich
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errSave
Linezolid prevents fibroblast activation and ameliorates tissue fibrosis by inhibition of mitochondrial translation
errArthritis & Rheumatology
IF10.9
err2025-11-14
err0
errOAAI
errXuezhi Hong; Yanhua Xiao; Haodong Qi; Shihao Zhu; Tim Filla; Andrea-Hermina Györfi; Yi-Nan Li; Meilin Xu; Langxian Zhi; Thuong Trinh-Minh; Clara Dees; Georg Schett; Jörg H.W. Distler; Alexandru-Emil Matei
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errSave
Impaired mitochondrial ketone body oxidation in insulin resistant states
erreBioMedicine
IF10.8
err2025-11-11
err0
errOAAI
errElric Zweck; Sarah Piel; Johannes W. Schmidt; Daniel Scheiber; Martin Schön; Sabine Kahl; Volker Burkart; Bedair Dewidar; Ricarda Remus; Alexandra Chadt; Hadi Al-Hasani; Lucia Mastrototaro; Hug Aubin; Udo Boeken; Artur Lichtenberg; Jörg Distler; Amin Polzin; Malte Kelm; Ralf Westenfeld; Robert Wagner; Patrick Schrauwen; Julia Szendroedi; Michael Roden; Cesare Granata
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S2k guidelines on diagnostics and treatment of systemic sclerosis Full version
errZEITSCHRIFT FUR RHEUMATOLOGIE
IF1
err2025-11-01
err0
PREAI
errHenes, Jorg C.; Arndt, Swantje; Berger, Melanie; Czihal, Michael; Distler, Jorg; Erbel, Christian; Frieling, Thomas; Gunther, Claudia; Haase, Isabell; Hunzelmann, Nicolas; Kotter, Ina; Oeschger, Michael; Jackowski, Jochen; Muller-Ladner, Ulf; Prasse, Antje; Riemekasten, Gabriela; Schirmer, Jan; Schmalzing, Marc; Schneider, Matthias; Schumacher, Falk; Worm, Margitta; Weiner, Stefan M.; Blank, Norbert
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S2k guideline Diagnosis and therapy of systemic sclerosis Summary
errZEITSCHRIFT FUR RHEUMATOLOGIE
IF1
err2025-11-01
err0
PREAI
errHenes, Jorg C.; Arndt, Swantje; Berger, Melanie; Czihal, Michael; Distler, Jorg; Erbel, Christian; Frieling, Thomas; Gunther, Claudia; Haase, Isabell; Hunzelmann, Nicolas; Kotter, Ina; Oeschger, Michael; Jackowski, Jochen; Muller-Ladner, Ulf; Prasse, Antje; Riemekasten, Gabriela; Schirmer, Jan; Schmalzing, Marc; Schneider, Matthias; Schumacher, Falk; Worm, Margitta; Weiner, Stefan M.; Blank, Norbert
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errSave
Emerging therapies for the treatment of systemic sclerosis
errNature Reviews Rheumatology
IF32.7
err2025-09-08
err0
PREAI
errJörg H. W. Distler; Masataka Kuwana; Shervin Assassi; Christopher P. Denton
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A screening tool to detect interstitial lung disease in systemic sclerosis: the ILD-RISC score
errRHEUMATOLOGY
IF4.4
err2025-09-01
err1
PREAI
errBruni, Cosimo; Tofani, Lorenzo; Fretheim, Havard; Liem, Sophie I. E.; Velauthapillai, Arthiha; Bjorkekjaer, Hilde; Barua, Imon; Galetti, Ilaria; Garaiman, Alexandru; Becker, Mike O.; Hoffmann-Vold, Anna-Maria; de Vries-Bouwstra, Jeska; Vonk, Madelon C.; Distler, Jorg H. W.; Matucci-Cerinic, Marco; Distler, Oliver
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Local immune effector cell-associated toxicity syndrome in CAR T-cell treated patients with refractory systemic lupus erythematosus – Authors' reply
errlancet rheumatology
IF0
err2025-08-12
err0
PREAI
errMelanie Hagen; Fabian Müller; Andreas Wirsching; Soraya Kharboutli; Silvia Spoerl; Christina Düsing; Tobias Krickau; Markus Metzler; Simon Völkl; Michael Aigner; Sascha Kretschmann; Ingrid Vasova; Marc Saake; Stefan Schliep; Torsten Kubacki; Nicolas Hunzelmann; Laura Bucci; Jule Taubmann; Christina Bergmann; Andrea-Hermina Györfi; Sascha Dietrich; Jörg H W Distler; Ricardo Grieshaber-Bouyer; Andreas Mackensen; Georg Schett
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Persisting CD19.CAR-T cells in combination with nintedanib: clinical response in a patient with systemic sclerosis-associated pulmonary fibrosis after 2 years
errThe Lancet Respiratory Medicine
IF0
err2025-05-28
err0
PREAI
errWolfgang Merkt; Manuel Röhrich; Eleni Mavriopoulou; Ayla Nadja Stütz; Jörg H W Distler; Anita Schmitt; Markus Polke; Claus Peter Heußel; Michael Schmitt; Hanns-Martin Lorenz
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An international perspective on the future of systemic sclerosis research (vol 21, pg 174, 2025)
errNATURE REVIEWS RHEUMATOLOGY
IF32.7
err2025-03-03
err0
PREAI
errAbraham, David J.; Black, Carol M.; Denton, Christopher P.; Distler, Joerg H. W.; Domsic, Robyn; Feghali-Bostwick, Carol; Gourh, Pravitt; Kolling, Fred; Kuwana, Masataka; Lafyatis, Robert; Landegren, Ulf; Mahoney, J. Matthew; Martin, Javier; Matucci-Cerinic, Marco; Mcmahan, Zsuzsanna H.; Mora, Ana L.; Mouthon, Luc; Rabinovitch, Marlene; Rojas, Mauricio; Rubin, Kristofer; Trojanowska, Maria; Varga, John; Whitfield, Michael L.; Gabrielli, Armando; Krieg, Thomas
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Evaluation of Systemic Sclerosis Primary Heart Involvement and Chronic Heart Failure in the European Scleroderma Trials and Research Cohort
errJOURNAL OF THE AMERICAN HEART ASSOCIATION
IF5.3
err2025-02-26
err0
errOAAI
errGyoerfi, Andrea-Hermina; Filla, Tim; Polzin, Amin; Tascilar, Koray; Buch, Maya; Troebs, Monique; Matei, Alexandru-Emil; Airo, Paolo; Balbir-Gurman, Alexandra; Kuwert, Frederic; Mihai, Carina; Kabala, Anna; Grasshoff, Hanna; Callaghan, Julia; Isomura, Yohei; Mansour, Jennifer; Spierings, Julia; Tennoe, Anders Heiervang; Selvi, Enrico; Riccieri, Valeria; Hoffmann-Vold, Anna-Maria; Bergmann, Christina; Schett, Georg; Hunzelmann, Nicolas; van Laar, Jacob M.; Saketkoo, Lesley Ann; Kuwana, Masataka; Siegert, Elise; Riemekasten, Gabriela; Distler, Oliver; du Four, Tessa; Smith, Vanessa; Truchetet, Marie-Elise; Distler, Joerg H. W.; EUSTAR Collaborators
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Successful generation of fully human, second generation, anti-CD19 CAR T cells for clinical use in patients with diverse autoimmune disorders
errCYTOTHERAPY
IF3.2
err2025-02-01
err2
errOAAI
errMougiakakos, Dimitrios; Sengupta, Ranjita; Gold, Ralf; Schroers, Roland; Haghikia, Aiden; Lorente, Mario; Pendleton, Michael; Register, Ames; Heesen, Christoph; Kro, Nicolaus; Schett, Georg; Mackensen, Andreas; Podoll, Amber; Gutman, Jonathan; Furie, Richard; Bayer, Ruthee; Distler, Jorg H. W.; Dietrich, Sascha; Kronke, Gerhard; Bullinger, Lars; Walker, Karen
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Research Directions

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Co-authors
Cooperation Journals
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Mark P. Mattson
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Marco Colonna
H-index: 170 · Papers: 848
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Cisca Wijmenga
H-index: 169 · Papers: 996
G
Georg Schett
H-index: 154 · Papers: 1.7K
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李金 (Jin Li)
H-index: 149 · Papers: 4.5K
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