Philip A. Cole - Publications, H-index & Citations

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Philip A. Cole

Harvard University

89H-index

537Paper Count

3.2WCitation Count

Published Papers 196

Publication Date

The CoREST complex inhibitor, corin, decreases tumor growth, increases cellular differentiation and extends lifespan in ATRT xenograft models

Neuro-Oncology

IF13.4

2026-07-21

PREAI

Anupa Geethadevi; Nikhil Vaidya; Robert J Fisher; Tyler R Findlay; Yiming Deng; Khoa Pham; Vikas Kumar; Samuel Beck; Jun Choe; Shiyu Liu; Calixto-Hope G Lucas; Charles G Eberhart; Jinchong Xu; Philip A Cole; Jeffrey Rubens; Marianne Collard; Eric H Raabe; Rhoda M Alani

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Histone modification cross-talk: analytical tools and molecular mechanisms

Biochemical Journal

IF4.3

2026-05-01

PREAI

Jiang, Jennifer; DuBois-Coyne, Sarah; Nam, Eunju; Whedon, Samuel D.; Lee, Kwangwoon; Cole, Philip A.

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Genetic mutations and inhibitors of p300 and CBP

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

IF0

2026-04-28

PREAI

Agnieszka Robaszkiewicz; Philip A. Cole

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Interaction of NDRG1 and MRE11 Modulates DNA Replication and Repair

Cancers

IF4.4

2026-04-21

OAAI

Hanna M. Doh; Nina Kozlova; Zhipeng A. Wang; Hwan Bae; Philip A. Cole; Taru Muranen

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Cancer-associated fibroblasts regulate DNA repair in pancreatic cancer through NDRG1-mediated R-loop processing

Nature Cell Biology

IF19.1

2026-04-01

PREAI

Kozlova, Nina; Cruz, Kayla A.; Ruzette, Antoine A.; Doh, Hanna M.; Willis, Nicholas A.; Hong, Su Min; Gonzalez, Raul S.; Vyas, Monika; Selfors, Laura M.; Dreyer, Stephan; Upstill-Goddard, Rosie; Faia, Kerrie L.; Wenglowsky, Steve; Close, Josh; Beutel, Alica; Jutric, Zeljka; Oliphant, Michael U. J.; Poluben, Larysa; Thapa, Byanjana; Taylor, Martin S.; Mustonen, Venla; Mangalath, Pradeep; Halbrook, Christopher J.; Grossman, Joseph E.; Hwang, Rosa F.; Clohessy, John G.; Ruskamo, Salla; Kursula, Petri; Petrova, Boryana; Kanarek, Naama; Cole, Philip A.; Chang, David K.; Evans, Conor L.; Norrelykke, Simon F.; Scully, Ralph; Muranen, Taru

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Structural basis for the recruitment and selective phosphorylation of Akt by mTORC2

Science

IF45.8

2025-11-27

PREAI

Martin S. Taylor; Maggie Chen; Matthew Hancock; Maximilian Wranik; Bryant D. Miller; Timothy R. O’Meara; Brad A. Palanski; Scott B. Ficarro; Brian J. Groendyke; Yufei Xiang; Kazuma T. Kondo; Karen Y. Linde-Garelli; Michelle J. Lee; Dibyendu Mondal; Daniel Freund; Samantha Congreve; Kaay Matas; Maximiliaan Hennink; Kera Xibinaku; Max L. Valenstein; Trevor van Eeuwen; Jarrod A. Marto; Andrej Sali; Yi Shi; Nathanael S. Gray; David M. Sabatini; Nam Chu; Kacper B. Rogala; Philip A. Cole

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OBITUARY A tribute to Richard L. Maas (1954-2025)

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2025-11-17

PREAI

Haghighi, Alireza; Lachke, Salil A.; Frank, Natasha Y.; Goessling, Wolfram; Cole, Philip A.

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Hydantion indolinones as AANAT inhibitors

Bioorganic & Medicinal Chemistry Letters

IF2.2

2025-10-30

PREAI

Nicole Wandrey; Jake Boley; Dirce Gómez-Galicia; Mackinzi Hill; Mason Bach; Sidney Gawrych; Mackenzie Hagemeister; Philip A. Cole; Michael A. Moxley; Allen A. Thomas

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DNA bendability regulates transcription factor binding to nucleosomes

Nature Structural & Molecular Biology

IF10.1

2025-08-25

PREAI

Luca Mariani; Xiao Liu; Kwangwoon Lee; Stephen S. Gisselbrecht; Philip A. Cole; Martha L. Bulyk

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Biochemistry and regulation of histone lysine l-lactylation

Nature Reviews Molecular Cell Biology

IF90.2

2025-08-19

PREAI

Xinlei Sheng; Hening Lin; Philip A. Cole; Yingming Zhao

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Biochemical analysis of PD-L1 ubiquitination by CRL3SPOP, ARIH1, and NEDD4 family ubiquitin ligases

Structure

IF4.3

2025-06-04

PREAI

Guojiao Xie; Lin Gao; Renee Lu; Linxia Tian; Tiantian Zheng; Xinning Li; Yongjun Dang; Philip A. Cole; Xian Yu; Hanjie Jiang; Zan Chen

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Deubiquitinase processing of a non-natural linkage of ubiquitinated-PTEN

BIOORGANIC CHEMISTRY

IF4.7

2025-04-01

PREAI

Iwase, Reina; Maisonet, Isabella Jaen; Lee, Kwangwoon; Buhrlage, Sara J.; Cole, Philip A.

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A Small-Molecule Inhibitor of Gut Bacterial Urease Protects the Host from Liver Injury

ACS CHEMICAL BIOLOGY

IF3.8

2025-01-08

PREAI

Richards-Corke, Khyle C.; Jiang, Yindi; Yeliseyev, Vladimir; Zhang, Yancong; Franzosa, Eric A.; Wang, Zhipeng A.; Abeywardana, Maheeshi Yapa; Cole, Phillip A.; Huttenhower, Curtis; Bry, Lynn; Balskus, Emily P.

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Circular Engineered Sortase for Interrogating Histone H3 in Chromatin

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-11-25

OAAI

Whedon, Samuel D.; Lee, Kwangwoon; Wang, Zhipeng A.; Zahn, Emily; Lu, Congcong; Abeywardana, Maheeshi Yapa; Fairall, Louise; Nam, Eunju; DuBois-Coyne, Sarah; De Ioannes, Pablo; Sheng, Xinlei; Andrei, Adelina; Lundberg, Emily; Jiang, Jennifer; Armache, Karim-Jean; Zhao, Yingming; Schwabe, John W. R.; Wu, Mingxuan; Garcia, Benjamin A.; Cole, Philip A.

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Targeting lysine acetylation readers and writers

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2024-11-21

PREAI

Zhou, Ming-Ming; Cole, Philip A.

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Multifaceted regulation of sirtuin 2 (Sirt2) deacetylase activity

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-09-01

OAAI

Abeywardana, Maheeshi Yapa; Whedon, Samuel D.; Lee, Kwangwoon; Nam, Eunju; Dovarganes, Rafael; DuBois-Coyne, Sarah; Haque, Ishraq A.; Wang, Zhipeng A.; Cole, Philip A.

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Protein semisynthesis reveals plasticity in HECT E3 ubiquitin ligase mechanisms

NATURE CHEMISTRY

IF20.2

2024-07-19

PREAI

Jiang, Hanjie; Miller, Bryant D.; Viennet, Thibault; Kim, Hyojeon; Lee, Kwangwoon; Arthanari, Haribabu; Cole, Philip A.

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Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1

NATURE CHEMICAL BIOLOGY

IF13.7

2024-07-04

PREAI

Lee, Kwangwoon; Barone, Marco; Waterbury, Amanda L.; Jiang, Hanjie; Nam, Eunju; DuBois-Coyne, Sarah E.; Whedon, Samuel D.; Wang, Zhipeng A.; Caroli, Jonatan; Neal, Katherine; Ibeabuchi, Brian; Dhoondia, Zuzer; Kuroda, Mitzi I.; Liau, Brian B.; Beck, Samuel; Mattevi, Andrea; Cole, Philip A.

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A MOZ-TIF2 leukemia mouse model displays KAT6-dependent H3K23 propionylation and overexpression of a set of active developmental genes

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-06-18

OAAI

Smolko, Anne E.; Sullivan, Daniel W.; Olsen, Sarah Naomi; Kang, Hyuckjoon; Whedon, Samuel D.; Baell, Jonathan B.; Cole, Philip A.; Armstrong, Scott A.; Kuroda, Mitzi I.

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TARGETING ATYPICAL TERATOID RHABDOID TUMORS USING A NOVEL BI-FUNCTIONAL COREST INHIBITOR

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Geethadevi, Anupa; Collard, Marianne; Findlay, Tyler; Fisher, Robert; Vaidya, Nikhil; Deng, Yiming; Eberhart, Charles; Cole, Philip; Alani, Rhoda; Rubens, Jeffrey; Raabe, Eric

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Research Directions