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Sarah K. Wootton

university of guelph

31H-index
205Paper Count
3.0KCitation Count
Published Papers 60
Publication Date
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Vectored Immunoprophylaxis for Mucosal Immunity: Advances and Challenges Associated with Recombinant Secretory IgA Expression
errVaccines
IF3.4
err2026-08-13
err0
errOAAI
errBenjamin J. Manchester; Jennifer L. Gommerman; Shayan Sharif; Leonardo Susta; Sarah K. Wootton
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Improving the precision of AAV lung gene therapy for SP-B deficiency using computationally derived lung-specific promoters
errGene Therapy
IF4.5
err2026-06-30
err0
PREAI
errNicole Zielinska; Erin. L. Howard; Brenna A. Y. Stevens; Melanie M. Goens; Elena S. B. Campbell; Madison E. Hughes; Yanlong Pei; Liqun Xu; Adithya Achuthan; Arul Vadivel; Arnold Apostol; Xiaolin He; Dinghai Zheng; D. Benjamin Gordon; Raja R. Srinivas; Alec A. K. Nielsen; Jeff L. Caswell; Luis G. Arroyo; Darren A. Yuen; Bernard Thebaud; Sarah K. Wootton
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errSave
Identification of computationally designed skeletal and cardiac promoters with high specificity across AAV delivery routes
errBMC Biotechnology
IF3.4
err2026-03-26
err0
errOAAI
errNicole Zielinska; Erin L. Howard; Brenna A. Y. Stevens; Melanie M. Goens; Cici Yang; Elena S. B. Campbell; Madison E. Hughes; Yanlong Pei; Dinghai Zheng; D. Benjamin Gordon; Alec A. K. Nielsen; Raja R. Srinivas; Jeff L. Caswell; Luis G. Arroyo; Sarah K. Wootton
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errSave
Activation of RIPK3 drives PANoptosis in human cells and inflammatory apoptosis in canine cells dependent on RIPK1, FADD and caspases
errApoptosis
IF8.1
err2026-01-12
err0
PREAI
errSarah M. Worfolk; Noah J. Phippen; Shayla G. Verburg; Katrina A. Kobal; Nicholas C. Langelaan; Davier G. Gongora; Jennifer Geddes-McAlister; Sarah K. Wootton; Matthew S. Miller; Samuel T. Workenhe
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errSave
Lung tropic dual AAV-SP-C and microRNA gene therapy attenuates lung injury in mutant Sftpc mice
errMolecular Therapy
IF12
err2025-12-24
err0
errOAAI
errPauline Bardin; Liqun Xu; Yanlong Pei; Adithya Achuthan Vineeth; Kennedy Nangle; Shumei Zhong; Chanèle Cyr-Depauw; Arul Vadivel; Emily Martin; Timothy E. Weaver; Sneha Sitaraman; Sarah K. Wootton; Bernard Thébaud
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Oncolytic Newcastle-disease-virus-mediated CD47 blockade in preclinical melanoma and pancreatic cancer models
errMolecular Therapy Oncology
IF5.3
err2025-11-01
err0
errOAAI
errYates, Jacob G. E.; Chan, Lily; Bogle, Alyssa E.; Campbell, Elena S. B.; Gillies, Arielle N.; Hughes, Madison E.; Mcausland, Thomas M.; Susta, Leonardo; Karimi, Khalil; Workenhe, Samuel T.; Wootton, Sarah K.
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errSave
SARS-COV-2 Vaccination Response in Non-Domestic Species Housed at the Toronto Zoo
errVaccines 2025, Vol. 13, Page 1037
IF3.4
err2025-10-08
err0
errOAAI
errSara Pagliarani; Jaime Tuling; Phuc H. Pham; Alexander Leacy; Pauline Delnatte; Brandon N. Lillie; Nicholas Masters; Jamie Sookhoo; Shawn Babiuk; Sarah K. Wootton; Leonardo Susta
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errSave
Vaccination against SARS-CoV-2 provides low-level cross-protection against common cold coronaviruses in mouse and non-human primate animal models
errJOURNAL OF VIROLOGY
IF3.8
err2025-02-25
err1
errOAAI
errNaghibosadat, Maedeh; Babuadze, George Giorgi; Pei, Yanlong; Hurst, Jacklyn; Salvant, Elsa; Gaete, Kayla; Biondi, Mia; Moloo, Badru; Goldstein, Alyssa; Avery, Stacey; Ma, Kathleen; Pietraszek, Anna; Wootton, Sarah K.; Alhaboub, Assad; Martin, Benjamin; Mubareka, Samira; Corredor, Juan; Sultana, Azmiri; Adeekoa, Adebayo; Budylowski, Patrick; Ostrowski, Mario; Chao, Jesse; Nagy, Eva; Kozak, Robert
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Anti-Drug Antibody Response to Therapeutic Antibodies and Potential Mitigation Strategies
errBIOMEDICINES
IF3.9
err2025-01-26
err0
errOAAI
errHoward, Erin L.; Goens, Melanie M.; Susta, Leonardo; Patel, Ami; Wootton, Sarah K.
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errSave
Rapid Development of Small Rodent Animal Models for Infectious Disease Research Through Vectorized Receptor Molecule Expression
errVIRUSES-BASEL
IF3.5
err2024-11-19
err0
errOAAI
errGoens, Melanie M.; Howard, Erin L.; Warner, Bryce M.; Susta, Leonardo; Wootton, Sarah K.
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errSave
Intranasal vaccination with an NDV-vectored SARS-CoV-2 vaccine protects against Delta and Omicron challenges
errNPJ VACCINES
IF6.5
err2024-05-23
err6
errOAAI
errWarner, Bryce M.; Yates, Jacob G. E.; Vendramelli, Robert; Truong, Thang; Meilleur, Courtney; Chan, Lily; Leacy, Alexander; Pham, Phuc H.; Pei, Yanlong; Susta, Leonardo; Wootton, Sarah K.; Kobasa, Darwyn
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errSave
Analysis of the impact of pluronic acid on the thermal stability and infectivity of AAV6.2FF
errBMC BIOTECHNOLOGY
IF3.4
err2024-04-25
err0
errOAAI
errThomas, Sylvia P.; Spinelli, Marcus M.; Rghei, Amira D.; Lopes, Jordyn A.; Zielinska, Nicole; McLeod, Benjamin M.; Pei, Yanlong; Zhang, Wei; Thebaud, Bernard; Karimi, Khalil; Wootton, Sarah K.
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errSave
Mucosal Vaccination with a Newcastle Disease Virus-Vectored Vaccine Reduces Viral Loads in SARS-CoV-2-Infected Cynomolgus Macaques
errVACCINES
IF3.4
err2024-04-10
err2
errOAAI
errWarner, Bryce M.; Chan, Mable; Tailor, Nikesh; Vendramelli, Robert; Audet, Jonathan; Meilleur, Courtney; Truong, Thang; Garnett, Lauren; Willman, Marnie; Soule, Geoff; Tierney, Kevin; Albietz, Alixandra; Moffat, Estella; Higgins, Rick; Santry, Lisa A.; Leacy, Alexander; Pham, Phuc H.; Yates, Jacob G. E.; Pei, Yanlong; Safronetz, David; Strong, James E.; Susta, Leonardo; Embury-Hyatt, Carissa; Wootton, Sarah K.; Kobasa, Darwyn
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errSave
Recombinant Newcastle disease viruses expressing immunological checkpoint inhibitors induce a pro-inflammatory state and enhance tumor-specific immune responses in two murine models of cancer
errFRONTIERS IN MICROBIOLOGY
IF4.5
err2024-01-24
err2
errOAAI
errSantry, Lisa A.; van Vloten, Jacob P.; AuYeung, Amanda W. K.; Mould, Robert C.; Yates, Jacob G. E.; McAusland, Thomas M.; Petrik, James J.; Major, Pierre P.; Bridle, Byram W.; Wootton, Sarah K.
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errSave
AAV Vectors Pseudotyped with Capsids from Porcine and Bovine Species Mediate In Vitro and In Vivo Gene Delivery
errVIRUSES-BASEL
IF3.5
err2023-12-29
err2
errOAAI
errYu, Darrick L.; van Lieshout, Laura P.; Stevens, Brenna A. Y.; Near, Kelsie J. (Jagt); Stodola, Jenny K.; Stinson, Kevin J.; Slavic, Durda; Wootton, Sarah K.
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errSave
A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency
errMOLECULAR THERAPY
IF12
err2023-12-01
err2
errOAAI
errThomas, Sylvia P.; Domm, Jakob M.; Vloten, Jacob P. van; Xu, Liqun; Vadivel, Arul; Yates, Jacob G. E.; Pei, Yanlong; Ingrao, Joelle; Lieshout, Laura P. van; Jackson, Sergio R.; Minott, Jessica A.; Achuthan, Adithya; Mehrani, Yeganeh; Mcausland, Thomas M.; Zhang, Wei; Karimi, Khalil; Vaughan, Andrew E.; de Jong, Jondavid; Kang, Martin H.; Thebaud, Bernard; Wootton, Sarah K.
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Kinetic analysis of oncolytic OrfV-induced innate and adaptive immune responses in a murine model of late-stage ovarian cancer
errMOLECULAR THERAPY ONCOLYTICS
IF5.3
err2023-12-01
err1
errOAAI
errMinott, Jessica A.; Vloten, Jacob P. van; Yates, Jake G. E.; Santry, Lisa A.; Matuszewska, Kathy; Pereira, Madison; Goens, Melanie M.; Viloria-Petit, Alicia M.; Wood, Geoffrey A.; Karimi, Khalil; Petrik, James J.; Bridle, Byram W.; Wootton, Sarah K.
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AAV-Vectored Expression of Marburg Virus-Neutralizing Antibody MR191 Provides Complete Protection From Challenge in a Guinea Pig Model
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2023-08-28
err5
errOAAI
errRghei, Amira D.; Cao, Wenguang; He, Shihua; Lopes, Jordyn A.; Zielinska, Nicole; Pei, Yanlong; Thompson, Brad; Banadyga, Logan; Wootton, Sarah K.
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errSave
Recent Advancements in AAV-Vectored Immunoprophylaxis in the Nonhuman Primate Model
errBIOMEDICINES
IF3.9
err2023-08-08
err3
errOAAI
errCampbell, Elena S. B.; Goens, Melanie M.; Cao, Wenguang; Thompson, Brad; Susta, Leonardo; Banadyga, Logan; Wootton, Sarah K.
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errSave
Gene therapy for Fabry disease: Progress, challenges, and outlooks on gene-editing (vol 134, pg 117, 2021)
errMOLECULAR GENETICS AND METABOLISM
IF3.5
err2023-05-01
err0
errOAAI
errDomm, Jakob M.; Wootton, Sarah K.; Medin, Jeffrey A.; West, Michael L.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
J
Jeffrey A. Whitsett
H-index: 136 · Papers: 759
A
A. Dusty Miller
H-index: 92 · Papers: 337
D
David B. Weiner
H-index: 92 · Papers: 805
J
Jack Lawler
H-index: 82 · Papers: 283
P
Pablo Tebas
H-index: 77 · Papers: 375
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