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A novel in vitro high-content imaging assay for the prediction of drug-induced lung toxicity Fitzpatrick, Paul A.; Johansson, Julia; Maglennon, Gareth; Wallace, Ian; Hendrickx, Ramon; Stamou, Marianna; Balogh Sivars, Kinga; Busch, Susann; Johansson, Linnea; Van Zuydam, Natalie; Patten, Kelley; Aberg, Per M.; Ollerstam, Anna; Hornberg, Jorrit J. Share Save
Metabolism-driven in vitro/in vivo disconnect of an oral ERα VHL-PROTAC Hayhow, Thomas G.; Williamson, Beth; Lawson, Mandy; Cureton, Natalie; Braybrooke, Erin L.; Campbell, Andrew; Carbajo, Rodrigo J.; Cheraghchi-Bashi, Azadeh; Chiarparin, Elisabetta; Diene, Coura R.; Fallan, Charlene; Fisher, David I.; Goldberg, Frederick W.; Hopcroft, Lorna; Hopcroft, Philip; Jackson, Anne; Kettle, Jason G.; Klinowska, Teresa; Kuenzel, Ulrike; Lamont, Gillian; Lewis, Hilary J.; Maglennon, Gareth; Martin, Scott; Gutierrez, Pablo Morentin; Morrow, Christopher J.; Nikolaou, Myria; Nissink, J. Willem M.; O'Shea, Patrick; Polanski, Radoslaw; Schade, Markus; Scott, James S.; Smith, Aaron; Weber, Judith; Wilson, Joanne; Yang, Bin; Crafter, Claire Share Save
The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER+ Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance Lawson, Mandy; Cureton, Natalie; Ros, Susana; Cheraghchi-Bashi, Azadeh; Urosevic, Jelena; D'Arcy, Sophie; Delpuech, Oona; Dupont, Michelle; Fisher, David I.; Gangl, Eric T.; Lewis, Hilary; Trueman, Dawn; Wali, Neha; Williamson, Stuart C.; Moss, Jennifer; Montaudon, Elodie; Derrien, Heloise; Marangoni, Elisabetta; Miragaia, Ricardo J.; Gagrica, Sladjana; Morentin-Gutierrez, Pablo; Moss, Thomas A.; Maglennon, Gareth; Sutton, Daniel; Polanski, Radoslaw; Rosen, Alan; Cairns, Jonathan; Zhang, Pei; Sanchez-Guixe, Monica; Serra, Violeta; Critchlow, Susan E.; Scott, James S.; Lindemann, Justin P. O.; Barry, Simon T.; Klinowska, Teresa; Morrow, Christopher J.; Carnevalli, Larissa Share Save
Targeted Desorption Electrospray Ionization Mass Spectrometry Imaging for Drug Distribution, Toxicity, and Tissue Classification Studies Dannhorn, Andreas; Doria, Maria Luisa; McKenzie, James; Inglese, Paolo; Swales, John G. G.; Hamm, Gregory; Strittmatter, Nicole; Maglennon, Gareth; Ghaem-Maghami, Sadaf; Goodwin, Richard J. A.; Takats, Zoltan Share Save
Statistical analysis of preclinical inter-species concordance of histopathological findings in the eTOX database Wright, Peter S. R.; Briggs, Katharine A.; Thomas, Robert; Smith, Graham F.; Maglennon, Gareth; Mikulskis, Paulius; Chapman, Melissa; Greene, Nigel; Phillips, Benjamin U.; Bender, Andreas Share Save
Retrospective analysis of the potential use of virtual control groups in preclinical toxicity assessment using the eTOX database Wright, Peter S. R.; Smith, Graham F.; Briggs, Katharine A.; Thomas, Robert; Maglennon, Gareth; Mikulskis, Paulius; Chapman, Melissa; Greene, Nigel; Phillips, Benjamin U.; Bender, Andreas Share Save
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Preclinical Characterization of AZD5305, A Next-Generation, Highly Selective PARP1 Inhibitor and Trapper br Illuzzi, Giuditta; Staniszewska, Anna D.; Gill, Sonja J.; Pike, Andy; McWilliams, Lisa; Critchlow, Susan E.; Cronin, Anna; Fawell, Stephen; Hawthorne, Glen; Jamal, Kunzah; Johannes, Jeffrey; Leonard, Emilyanne; Macdonald, Ruth; Maglennon, Gareth; Nikkila, Jenni; O'Connor, Mark J.; Smith, Aaron; Southgate, Harriet; Wilson, Joanne; Yates, James; Cosulich, Sabina; Leo, Elisabetta Share Save
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Method To Visualize the Intratumor Distribution and Impact of Gemcitabine in Pancreatic Ductal Adenocarcinoma by Multimodal Imaging Strittmatter, Nicole; Richards, Frances M.; Race, Alan M.; Ling, Stephanie; Sutton, Daniel; Nilsson, Anna; Wallez, Yann; Barnes, Jennifer; Maglennon, Gareth; Gopinathan, Aarthi; Brais, Rebecca; Wong, Edmond; Serra, Maria Paola; Atkinson, James; Smith, Aaron; Wilson, Joanne; Hamm, Gregory; Johnson, Timothy, I; Dunlop, Charles R.; Kaistha, Brajesh P.; Bunch, Josephine; Sansom, Owen J.; Takats, Zoltan; Andren, Per E.; Lau, Alan; Barry, Simon T.; Goodwin, Richard J. A.; Jodrell, Duncan, I Share Save
Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessment Hamm, Gregory; Maglennon, Gareth; Williamson, Beth; Macdonald, Ruth; Doherty, Ann; Jones, Stewart; Harris, Jayne; Blades, James; Harmer, Alexander R.; Barton, Peter; Rawlins, Philip B.; Smith, Paul; Winter-Holt, Jon; McMurray, Lindsay; Johansson, Julia; Fitzpatrick, Paul; McCoull, William; Coen, Muireann Share Save
Holistic Characterization of a Salmonella Typhimurium Infection Model Using Integrated Molecular Imaging Strittmatter, Nicole; Kanvatirth, Panchali; Inglese, Paolo; Race, Alan M.; Nilsson, Anna; Dannhorn, Andreas; Kudo, Hiromi; Goldin, Robert D.; Ling, Stephanie; Wong, Edmond; Seeliger, Frank; Serra, Maria Paola; Hoffmann, Scott; Maglennon, Gareth; Hamm, Gregory; Atkinson, James; Jones, Stewart; Bunch, Josephine; Andren, Per E.; Takats, Zoltan; Goodwin, Richard J. A.; Mastroeni, Pietro Share Save
Method to Investigate the Distribution of Water-Soluble Drug-Delivery Systems in Fresh Frozen Tissues Using Imaging Mass Cytometry Strittmatter, Nicole; England, Richard M.; Race, Alan M.; Sutton, Daniel; Moss, Jennifer, I; Maglennon, Gareth; Ling, Stephanie; Wong, Edmond; Rose, Jonathan; Purvis, Ian; Macdonald, Ruth; Barry, Simon T.; Ashford, Marianne B.; Goodwin, Richard J. A. Share Save
Deep Learning-Based Annotation Transfer between Molecular Imaging Modalities: An Automated Workflow for Multimodal Data Integration Race, Alan M.; Sutton, Daniel; Hamm, Gregory; Maglennon, Gareth; Morton, Jennifer P.; Strittmatter, Nicole; Campbell, Andrew; Sansom, Owen J.; Wang, Yinhai; Barry, Simon T.; Takats, Zoltan; Goodwin, Richard J. A.; Bunch, Josephine Share Save
Evaluation of UV-C Decontamination of Clinical Tissue Sections for Spatially Resolved Analysis by Mass Spectrometry Imaging (MSI) Dannhorn, Andreas; Ling, Stephanie; Powell, Steven; McCall, Eileen; Maglennon, Gareth; Jones, Gemma N.; Pierce, Andrew J.; Strittmatter, Nicole; Hamm, Gregory; Barry, Simon T.; Bunch, Josephine; Goodwin, Richard J. A.; Takats, Zoltan Share Save
Preclinical Comparison of the Blood-brain barrier Permeability of Osimertinib with Other EGFR TKIs Colclough, Nicola; Chen, Kan; Johnstrom, Peter; Strittmatter, Nicole; Yan, Yumei; Wrigley, Gail L.; Schou, Magnus; Goodwin, Richard; Varnas, Katarina; Adua, Sally J.; Zhao, Minghui; Nguyen, Don X.; Maglennon, Gareth; Barton, Peter; Atkinson, James; Zhang, Lin; Janefeldt, Annika; Wilson, Joanne; Smith, Aaron; Takano, Akihiro; Arakawa, Ryosuke; Kondrashov, Mikhail; Malmquist, Jonas; Revunov, Evgeny; Vazquez-Romero, Ana; Moein, Mohammad Mahdi; Windhorst, Albert D.; Karp, Natasha A.; Finlay, M. Raymond, V; Ward, Richard A.; Yates, James W. T.; Smith, Paul D.; Farde, Lars; Cheng, Zack; Cross, Darren A. E. Share Save
Not all selective estrogen receptor degraders are equal - Preclinical comparison of AZD9833, AZD9496 and fulvestrant Lawson, Mandy; Cureton, Natalie; DuPont, Michelle; Delpuech, Oona; Trueman, Dawn; Zhang, Pei; Cheraghchi-Bashi-Astaneh, Azadeh; Gagrica, Sladjana; Maglennon, Gareth; Sutton, Daniel; Zhang, Bairu; Cairns, Jonathan; Scott, Jamie; Klinowska, Teresa; Morrow, Christopher J. Share Save
Universal Sample Preparation Unlocking Multimodal Molecular Tissue Imaging Dannhorn, Andreas; Kazanc, Emine; Ling, Stephanie; Nikula, Chelsea; Karali, Evdoxia; Serra, Maria Paola; Vorng, Jean-Luc; Inglese, Paolo; Maglennon, Gareth; Hamm, Gregory; Swales, John; Strittmatter, Nicole; Barry, Simon T.; Sansom, Owen J.; Poulogiannis, George; Bunch, Josephine; Goodwin, Richard J. A.; Takats, Zoltan Share Save
Oral selective estrogen receptor degrader AZD9496 demonstrated preclinical model specific differences to fulvestrant in estrogen receptor degradation, agonism and anti-tumour effects Lawson, Mandy; Cureton, Natalie; Delpuech, Oona; Zhang, Pei; Cheraghchi-Bashi-Astaneh, Azadeh; Gagrica, Sladjana; Trueman, Dawn; Maglennon, Gareth; Sutton, Daniel; Zhang, Bairu; Cairns, Jonathan; Klinowska, Teresa; Morrow, Christopher J. Share Save
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