Not logged in Share Save
Share Save
Chromosome end protection by RAP1-mediated inhibition of DNA-PK (Apr, 10.1038/s41586-025-08896-1, 2025) Eickhoff, Patrik; Sonmez, Ceylan; Fisher, Charlotte E. L.; Inian, Oviya; Roumeliotis, Theodoros I.; dello Stritto, Angela; Mansfeld, Joerg; Choudhary, Jyoti S.; Guettler, Sebastian; Lottersberger, Francisca; Douglas, Max E. Share Save
Chromosome end protection by RAP1-mediated inhibition of DNA-PK Eickhoff, Patrik; Sonmez, Ceylan; Fisher, Charlotte E. L.; Inian, Oviya; Roumeliotis, Theodoros I.; dello Stritto, Angela; Mansfeld, Jorg; Choudhary, Jyoti S.; Guettler, Sebastian; Lottersberger, Francisca; Douglas, Max E. Share Save
Share Save
Genetic and immune landscape evolution in MMR-deficient colorectal cancer Challoner, Benjamin R.; Woolston, Andrew; Lau, David; Buzzetti, Marta; Fong, Caroline; Barber, Louise J.; Anandappa, Gayathri; Crux, Richard; Assiotis, Ioannis; Fenwick, Kerry; Begum, Ruwaida; Begum, Dipa; Lund, Tom; Sivamanoharan, Nanna; Sansano, Harold B.; Domingo-Arada, Melissa; Tran, Amina; Pandha, Hardev; Church, David; Eccles, Bryony; Ellis, Richard; Falk, Stephen; Hill, Mark; Krell, Daniel; Murugaesu, Nirupa; Nolan, Luke; Potter, Vanessa; Saunders, Mark; Shiu, Kai-Keen; Guettler, Sebastian; Alexander, James L.; Lazare-Iglesias, Hector; Kinross, James; Murphy, Jamie; von Loga, Katharina; Cunningham, David; Chau, Ian; Starling, Naureen; Ruiz-Banobre, Juan; Dhillon, Tony; Gerlinger, Marco Share Save
Share Save
ADP-ribosyltransferases, an update on function and nomenclature Luscher, Bernhard; Ahel, Ivan; Altmeyer, Matthias; Ashworth, Alan; Bai, Peter; Chang, Paul; Cohen, Michael; Corda, Daniela; Dantzer, Francoise; Daugherty, Matthew D.; Dawson, Ted M.; Dawson, Valina L.; Deindl, Sebastian; Fehr, Anthony R.; Feijs, Karla L. H.; Filippov, Dmitri V.; Gagne, Jean-Philippe; Grimaldi, Giovanna; Guettler, Sebastian; Hoch, Nicolas C.; Hottiger, Michael O.; Korn, Patricia; Kraus, W. Lee; Ladurner, Andreas; Lehtio, Lari; Leung, Anthony K. L.; Lord, Christopher J.; Mangerich, Aswin; Matic, Ivan; Matthews, Jason; Moldovan, George-Lucian; Moss, Joel; Natoli, Gioacchino; Nielsen, Michael L.; Niepel, Mario; Nolte, Friedrich; Pascal, John; Paschal, Bryce M.; Pawlowski, Krzysztof; Poirier, Guy G.; Smith, Susan; Timinszky, Gyula; Wang, Zhao-Qi; Yelamos, Jose; Yu, Xiaochun; Zaja, Roko; Ziegler, Mathias Share Save
Share Save
Share Save
CEA expression heterogeneity and plasticity confer resistance to the CEA-targeting bispecific immunotherapy antibody cibisatamab (CEA-TCB) in patient-derived colorectal cancer organoids Gonzalez-Exposito, Reyes; Semiannikova, Maria; Griffiths, Beatrice; Khan, Khurum; Barber, Louise J.; Woolston, Andrew; Spain, Georgia; von Loga, Katharina; Challoner, Ben; Patel, Radhika; Ranes, Michael; Swain, Amanda; Thomas, Janet; Bryant, Annette; Saffery, Claire; Fotiadis, Nicos; Guettler, Sebastian; Mansfield, David; Melcher, Alan; Powles, Thomas; Rao, Sheela; Watkins, David; Chau, Ian; Matthews, Nik; Wallberg, Fredrik; Starling, Naureen; Cunningham, David; Gerlinger, Marco Share Save
Molecular subtypes and novel genetic mechanisms of primary and acquired anti-EGFR resistance in colorectal cancer in the Prospect C biomarker trial Khan, Khurum Hayat; Woolston, Andrew; Spain, Georgia; Barber, Louise; Patil, Yatish; Griffiths, Beatrice; GonzalezExposito, Reyes; Mansukhani, Sonia; Davies, Matthew; Rao, Sheela; Watkins, David; Sclafani, Francesco; Suntharanathan, Jana; Peckitt, Clare; Begum, Ruwaida; Rana, Isma; Thomas, Janet; Oates, Jacqui; Bryant, Annette; Wotherspoon, Andrew; Fotiadis, Nicos; Khan, Nasir; Guettler, Sebastian; von Loga, Katharina; Starling, Naureen; Chau, Ian; Sadanandam, Anguraj; Cunningham, David; Gerlinger, Marco Share Save
Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance Pettitt, Stephen J.; Krastev, Dragomir B.; Brandsma, Inger; Drean, Amy; Song, Feifei; Aleksandrov, Radoslav; Harrell, Maria I.; Menon, Malini; Brough, Rachel; Campbell, James; Frankum, Jessica; Ranes, Michael; Pemberton, Helen N.; Rafiq, Rumana; Fenwick, Kerry; Swain, Amanda; Guettler, Sebastian; Lee, Jung-Min; Swisher, Elizabeth M.; Stoynov, Stoyno; Yusa, Kosuke; Ashworth, Alan; Lord, Christopher J. Share Save
Share Save
MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway Couzens, Amber L.; Xiong, Shawn; Knight, James D. R.; Mao, Daniel Y.; Guettler, Sebastian; Picaud, Sarah; Kurinov, Igor; Filippakopoulos, Panagis; Sicheri, Frank; Gingras, Anne-Claude Share Save
Share Save
Share Save
The genomic landscape of oesophagogastric junctional adenocarcinoma Chong, Irene Y.; Cunningham, David; Barber, Louise J.; Campbell, James; Chen, Lina; Kozarewa, Iwanka; Fenwick, Kerry; Assiotis, Ioannis; Guettler, Sebastian; Garcia-Murillas, Isaac; Awan, Saima; Lambros, Maryou; Starling, Naureen; Wotherspoon, Andrew; Stamp, Gordon; Gonzalez-de-Castro, David; Benson, Martin; Chau, Ian; Hulkki, Sanna; Nohadani, Mahrokh; Eltahir, Zakaria; Lemnrau, Alina; Orr, Nicholas; Rao, Sheela; Lord, Christopher J.; Ashworth, Alan Share Save
Share Save
Share Save
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Not logged in.png){kind=icon}