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Alan Ashworth

University of California, San Francisco

121H-index
1.0KPaper Count
6.7WCitation Count
Published Papers 220
Publication Date
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Publisher Correction: Targeting cancer-specific mutations with RNA-triggered chromatin shredding
errNature
IF48.5
err2026-08-14
err0
PREAI
errJingkun Zeng; Zhiyuan Cheng; Huadong Chen; Zhaojun Wang; Jared Thompson; Kadin T. Crosby; Hesong Han; Arushi Singhal; Wayne Ngo; Chenglong Xia; Daniel Rosas-Rivera; Zeyuan Zhang; Min Hyung Kang; Ying Mao; Morgan E. Diolaiti; Giselle C. Lee; John F. X. Diffley; Yixuan Song; Longhui Qiu; Nathan M. Krah; Niren Murthy; Ryan N. Jackson; Yang Liu; Alan Ashworth; Jennifer A. Doudna
errShare
errSave
Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding
errNature
IF48.5
err2026-06-08
err0
PREAI
errJingkun Zeng; Zhiyuan Cheng; Huadong Chen; Zhaojun Wang; Jared Thompson; Kadin T. Crosby; Hesong Han; Arushi Singhal; Wayne Ngo; Chenglong Xia; Daniel Rosas-Rivera; Zeyuan Zhang; Min Hyung Kang; Ying Mao; Morgan E. Diolaiti; Giselle C. Lee; John F. X. Diffley; Yixuan Song; Longhui Qiu; Nathan M. Krah; Niren Murthy; Ryan N. Jackson; Yang Liu; Alan Ashworth; Jennifer A. Doudna
errShare
errSave
Two decades of PARP inhibitor synthetic lethality in cancer
errNature
IF48.5
err2026-05-06
err0
PREAI
errChristopher J. Lord; Andrew N. J. Tutt; Alan Ashworth
errShare
errSave
Identification of a Two-Gene Biomarker Correlated with Sensitivity to Combined PARP7 Inhibition and AHR Activation in Cancer Cells
errCancer Research Communications
IF0
err2026-01-01
err0
errOAAI
errGou, Xuxu; Chen, Huadong; Diolaiti, Morgan E.; Ashworth, Alan
errShare
errSave
Discovery of AVI-6451, a Potent and Selective Inhibitor of the SARS-CoV-2 ADP-Ribosylhydrolase Mac1 with Oral Efficacy In Vivo
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-12-01
err0
PREAI
errJaishankar, Priyadarshini; Correy, Galen J.; Matsui, Yusuke; Togo, Takaya; Rachman, Moira M.; Stevens, Maisie G. V.; Hantz, Eric R.; Zheng, Jeffrey; Diolaiti, Morgan E.; Montano, Mauricio; Taha, Taha Y.; Rosecrans, Julia; Pampel, Julius; Krogan, Nevan J.; Shoichet, Brian K.; Ashworth, Alan; Ott, Melanie; Fraser, James S.; Renslo, Adam R.
errShare
errSave
The Mac1 ADP-ribosylhydrolase is a therapeutic target for SARS-CoV-2
errELIFE
IF0
err2025-11-19
err1
errOAAI
errSuryawanshi, Rahul K.; Jaishankar, Priyadarshini; Correy, Galen J.; Rachman, Moira M.; O'leary, Patrick C.; Taha, Taha Y.; Matsui, Yusuke; Zapatero-Belinchon, Francisco J.; Mccavitt-Malvido, Maria; Doruk, Yagmur U.; Stevens, Maisie Gv; Diolaiti, Morgan E.; Jogalekar, Manasi P.; Chen, Huadong; Richards, Alicia L.; Kongpracha, Pornparn; Bali, Sofia; Montano, Mauricio; Rosecrans, Julia; Matthay, Michael; Togo, Takaya; Gonciarz, Ryan L.; Gopalkrishnan, Saumya; Neitz, R. Jeffrey; Krogan, Nevan J.; Swaney, Danielle L.; Shoichet, Brian K.; Ott, Melanie; Renslo, Adam R.; Ashworth, Alan; Fraser, James S.
errShare
errSave
An engineered cysteine sensor optimized for high-throughput screening identifies regulators of intracellular thiol levels
errCell Chemical Biology
IF7.2
err2025-11-10
err0
errOAAI
errRachel P.M. Abrams; Rebecca G. Donahue; Jessica Ma; Ying Mao; Morgan E. Diolaiti; Alan Ashworth
errShare
errSave
Coordinated protein modules define DNA damage responses to carboplatin at single-cell resolution in human ovarian carcinoma models
errCell Reports Medicine
IF10.6
err2025-08-22
err0
errOAAI
errJacob S. Bedia; Antonio Delgado-Gonzalez; Ying-Wen Huang; Veronica D. Gonzalez; Ionut-Gabriel Funingana; Zainab Rahil; Alyssa Mike; Alexis Lowber; Maria Vias; Alan Ashworth; James D. Brenton; Wendy J. Fantl
errShare
errSave
Correction: Assessing the Value of New Antimicrobials: Evaluations of Cefiderocol and Ceftazidime-Avibactam to Inform Delinked Payments by the NHS in England
errApplied Health Economics and Health Policy
IF3.3
err2025-06-02
err0
errOAAI
errBeth Woods; Ben Kearns; Laetitia Schmitt; Dina Jankovic; Claire Rothery; Sue Harnan; Jean Hamilton; Alison Scope; Shijie Ren; Laura Bojke; Mark Wilcox; William Hope; Colm Leonard; Philip Howard; David Jenkins; Alan Ashworth; Andrew Bentley; Mark Sculpher
errShare
errSave
Assessing the Value of New Antimicrobials: Evaluations of Cefiderocol and Ceftazidime-Avibactam to Inform Delinked Payments by the NHS in England
errAPPLIED HEALTH ECONOMICS AND HEALTH POLICY
IF3.3
err2024-11-30
err0
PREAI
errWoods, Beth; Kearns, Ben; Schmitt, Laetitia; Jankovic, Dina; Rothery, Claire; Harnan, Sue; Hamilton, Jean; Scope, Alison; Ren, Shijie; Bojke, Laura; Wilcox, Mark; Hope, William; Leonard, Colm; Howard, Philip; Jenkins, David; Ashworth, Alan; Bentley, Andrew; Sculpher, Mark
errShare
errSave
Transcription and DNA replication collisions lead to large tandem duplications and expose targetable therapeutic vulnerabilities in cancer
errNATURE CANCER
IF28.5
err2024-11-18
err0
PREAI
errYang, Yang; Badura, Michelle L.; O'Leary, Patrick C.; Delavan, Henry M.; Robinson, Troy M.; Egusa, Emily A.; Zhong, Xiaoming; Swinderman, Jason T.; Li, Haolong; Zhang, Meng; Kim, Minkyu; Ashworth, Alan; Feng, Felix Y.; Chou, Jonathan; Yang, Lixing
errShare
errSave
PARP7 Inhibitors and AHR Agonists Act Synergistically across a Wide Range of Cancer Models
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2024-09-23
err0
PREAI
errChen, Huadong; Gou, Xuxu; Mao, Ying; O'Leary, Patrick C.; Diolaiti, Morgan E.; Ashworth, Alan
errShare
errSave
Perivascular NOTCH3+ Stem Cells Drive Meningioma Tumorigenesis and Resistance to Radiotherapy
errCANCER DISCOVERY
IF33.3
err2024-05-10
err1
PREAI
errChoudhury, Abrar; Cady, Martha A.; Lucas, Calixto-Hope G.; Najem, Hinda; Phillips, Joanna J.; Palikuqi, Brisa; Zakimi, Naomi; Joseph, Tara; Birrueta, Janeth O.; Chen, William C.; Bush, Nancy A. Oberheim; Hervey-Jumper, Shawn L.; Klein, Ophir D.; Toedebusch, Christine M.; Horbinski, Craig M.; Magill, Stephen T.; Bhaduri, Aparna; Perry, Arie; Dickinson, Peter J.; Heimberger, Amy B.; Ashworth, Alan; Crouch, Elizabeth E.; Raleigh, David R.
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errSave
The DACH1 gene, frequently co-deleted with BRCA2 in prostate cancer, governs PARP inhibitor resistance
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errLi, Zhiping; Jiao, Xuanmao; Khan, Taimoor; Li, Danni; Zha, Shan; Phoon, Lai Yee; Lan, Li; Robertson, Gordon; Ashton, Anthony W.; Iczkowski, Kenneth A.; Borowsky, Alexander D.; Ashworth, Alan; Pestell, Richard G.
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errSave
A roadmap to establishing global oncology as a priority initiative within a National Cancer Institute-designated cancer center
errJNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
IF7.2
err2023-12-07
err1
errOAAI
errVan Loon, Katherine; Breithaupt, Lindsay; Ng, Dianna; DeBoer, Rebecca J.; Buckle, Geoffrey C.; Bialous, Stella; Hiatt, Robert A.; Volberding, Paul; Hermiston, Michelle L.; Ashworth, Alan
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errSave
A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo
errPLOS PATHOGENS
IF4.9
err2023-08-31
err11
errOAAI
errTaha, Taha Y.; Suryawanshi, Rahul K.; Chen, Irene P.; Correy, Galen J.; McCavitt-Malvido, Maria; O'Leary, Patrick C.; Jogalekar, Manasi P.; Diolaiti, Morgan E.; Kimmerly, Gabriella R.; Tsou, Chia-Lin; Gascon, Ronnie; Montano, Mauricio; Martinez-Sobrido, Luis; Krogan, Nevan J.; Ashworth, Alan; Fraser, James S.; Ott, Melanie
errShare
errSave
Generation and comparative analysis of an Itga8-CreERT2 mouse with preferential activity in vascular smooth muscle cells (vol 1, pg 1084, 2022)
errcardiovascular research
IF10.8
err2023-06-09
err0
errOAAI
errWarthi, Ganesh; Faulkner, Jessica L.; Doja, Jaser; Ghanam, Amr R.; Gao, Pan; Yang, Allison C.; Slivano, Orazio J.; Barris, Candee T.; Kress, Taylor C.; Zawieja, Scott D.; Griffin, Susan H.; Xie, Xiaoling; Ashworth, Alan; Christie, Christine K.; Bryant, William B.; Kumar, Ajay; Davis, Michael J.; Long, Xiaochun; Gan, Lin; de Chantemele, Eric J. Belin; Lyu, Qing R.; Miano, Joseph M.
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errSave
Investigation of the ubiquitin ligase RNF31 as a mediator of immune evasion in advanced prostate cancer
errCANCER RESEARCH
IF16.6
err2023-06-02
err0
PREAI
errLiu, Tianyi; Li, Haolong; Hua, Tony Junjie; Shin, Hyunjin; Shenoy, Tanushree; Sjoestroem, Martin; Lundberg, Arian; Gilbert, Luke; Quigley, David; Ashworth, Alan; Lanier, Lewis; Feng, Felix
errShare
errSave
AR suppresses MHC Class I expression and T-cell response in prostate cancer
errCANCER RESEARCH
IF16.6
err2023-06-02
err2
PREAI
errChesner, Lisa; Graff, Julie; Polesso, Fanny; Smith, Alexis; Lundberg, Arian; Sjoestroem, Martin; Xia, Zheng; Linder, Simon; Bergman, Andries; Ashworth, Alan; Quigley, David; Zwart, Wilbert; Gilbert, Luke; Moran, Amy; Feng, Felix
errShare
errSave
Biological insights and novel biomarker discovery through deep learning approaches in breast cancer histopathology
errNPJ BREAST CANCER
IF7.6
err2023-04-06
err19
errOAAI
errMandair, Divneet; Reis-Filho, Jorge S. S.; Ashworth, Alan
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Mark Gerstein
H-index: 191 · Papers: 1.2K
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Mark A. Rubin
H-index: 186 · Papers: 1.5K
C
Chuan He
H-index: 161 · Papers: 978
J
Johann S. de Bono
H-index: 160 · Papers: 2.5K
J
Jean‐Yves Blay
H-index: 158 · Papers: 2.4K
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