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Khaled Machaca

research department

33H-index
153Paper Count
3.5KCitation Count
Published Papers 62
Publication Date
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Unraveling Immune Dysregulation in ZNFX1 Deficiency: From Interferonopathies to Macrophage Activation Syndrome
errJournal of Clinical Immunology
IF5.7
err2026-08-06
err0
errOAAI
errSara G. Hamad; Melanie Makhlouf; Nourhen Agrebi; Ahmad Kaddourah; Mutasim Abu-Hasan; Buthaina Al-Adba; Ameera Sadoun; Satanay Z. Hubrack; Waleed Aamer; Mayra L. Ruiz Tejada Segura; Antonio Scialdone; Khaled Machaca; Luis R. Saraiva; Sharon Bout-Tabaku; Bernice Lo
errShare
errSave
Dynamic Regulation of PLCζ by Calmodulin and MARCKS May Underlie Calcium Oscillations during Human Fertilisation
errCell Calcium
IF4
err2026-05-14
err0
errOAAI
errAngelos Thanassoulas; Brian L. Calver; Alaaeldin Saleh; Luke Buntwal; Junaid Kashir; Nancy Nader; Khaled Machaca; Karl Swann; F. Anthony Lai; Michail Nomikos
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errSave
The Functional Interaction Between PRDM16 and the SREBP Pathway Controls Lipid Metabolism
errInternational Journal of Molecular Sciences 2025, Vol. 26, Page 10246
IF0
err2025-10-22
err0
errOAAI
errHafiz Majid Mahmood; Maria Teresa Bengoechea-Alonso; Dana E. Al-Ansari; Khaled Machaca; Johan Ericsson
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errSave
Scaling up neuronal Ca2+, signaling on ER ladders
errCELL CALCIUM
IF4
err2025-05-01
err0
PREAI
errMachaca, Khaled
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errSave
Ca2+ tunneling architecture and function are important for secretion
errJOURNAL OF CELL BIOLOGY
IF6.4
err2024-11-05
err0
PREAI
errCourjaret, Raphael J.; Wagner II, Larry E.; Ammouri, Rahaf R.; Yule, David I.; Machaca, Khaled
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errSave
Blockade of store-operated calcium entry by BTP2 preserves anti-inflammatory gene expression in human peripheral blood mononuclear cells
errHUMAN IMMUNOLOGY
IF2.2
err2024-11-01
err0
PREAI
errShankaranarayanan, Divya; Mantri, Madhav; Lagman, Mila; Li, Carol; Sharma, Vijay K.; Muthukumar, Thangamani; Xiang, Jenny Z.; De Vlaminck, Iwijn; Machaca, Khaled; Suthanthiran, Manikkam
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errSave
Loss of the TRPM4 channel in humans causes immune dysregulation with defective monocyte migration
errJOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
IF11.2
err2024-09-01
err0
errOAAI
errYu, Fang; Hubrack, Satanay; Raynaud, Christophe M.; Elmi, Asha; Mackeh, Rafah; Agrebi, Nourhen; Thareja, Gaurav; Belkadi, Abdelaziz; Al Saloos, Hesham; Ahmed, Ayeda Abdulsalam; Purayil, Saleema C.; Mohamoud, Yasmin A.; Suhre, Karsten; Khalil, Charbel Abi; Schmidt, Frank; Lo, Bernice; Hassan, Amel; Machaca, Khaled
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errSave
The Reappraisal of the Reappraisal-CRAC Channels Are Activated by L-Type Ca2+ Channel Blockers, Reply to Bird et al
errFUNCTION
IF3.8
err2024-02-02
err0
errOAAI
errTrebak, Mohamed; Machaca, Khaled; Hogan, Patrick G.
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errSave
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
errCELL CALCIUM
IF4
err2023-09-01
err3
errOAAI
errHammad, Ayat S.; Yu, Fang; Al-Hamaq, Jawaher; Horgen, F. David; Machaca, Khaled
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errSave
STAT1-and NFAT-independent amplification of purinoceptor function integrates cellular senescence with interleukin-6 production in preadipocytes
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2022-11-23
err1
errOAAI
errMajeed, Yasser; Madani, Aisha Y. Y.; Altamimi, Ahmed I. I.; Courjaret, Raphael; Vakayil, Muneera; Fountain, Samuel J. J.; Machaca, Khaled; Mazloum, Nayef A. A.
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errSave
The STIM1 Phosphorylation Saga
errCELL CALCIUM
IF4
err2022-05-01
err6
errOAAI
errYu, Fang; Machaca, Khaled
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errSave
A longer isoform of Stim1 is a negative SOCE regulator but increases cAMP-modulated NFAT signaling
errEMBO REPORTS
IF6.2
err2021-12-23
err17
errOAAI
errKnapp, Mona L.; Alansary, Dalia; Poth, Vanessa; Foerderer, Kathrin; Sommer, Frederik; Zimmer, David; Schwarz, Yvonne; Kuenzel, Nicolas; Kless, Achim; Machaca, Khaled; Helms, Volkhard; Muehlhaus, Timo; Schroda, Michael; Lis, Annette; Niemeyer, Barbara A.
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errSave
Phosphorylation of STIM1 at ERK/CDK sites is dispensable for cell migration and ER partitioning in mitosis
errCELL CALCIUM
IF4
err2021-12-01
err7
errOAAI
errHammad, Ayat S.; Yu, Fang; Botheju, Welathanthrige S.; Elmi, Asha; Alcantara-Adap, Ethel; Machaca, Khaled
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errSave
Native SOCE complexes: Small but mighty?
errCELL CALCIUM
IF4
err2021-07-01
err1
PREAI
errCourjaret, Raphael; Machaca, Khaled
errShare
errSave
Store Operated Calcium Entry in Cell Migration and Cancer Metastasis
errCELLS
IF5.2
err2021-05-19
err36
errOAAI
errHammad, Ayat S.; Machaca, Khaled
errShare
errSave
Novel ORAI1 Mutation Disrupts Channel Trafficking Resulting in Combined Immunodeficiency
errJOURNAL OF CLINICAL IMMUNOLOGY
IF5.7
err2021-03-01
err9
errOAAI
errYu, Fang; Agrebi, Nourhen; Mackeh, Rafah; Abouhazima, Khaled; KhudaBakhsh, Khadija; Adeli, Mehdi; Lo, Bernice; Hassan, Amel; Machaca, Khaled
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errSave
The carboxy terminal coiled-coil modulates Orai1 internalization during meiosis
errSCIENTIFIC REPORTS
IF3.9
err2021-01-27
err2
errOAAI
errHodeify, Rawad; Dib, Maya; Alcantara-Adap, Ethel; Courjaret, Raphael; Nader, Nancy; Reyes, Cleo Z.; Hammad, Ayat S.; Hubrack, Satanay; Yu, Fang; Machaca, Khaled
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errSave
Multifunctional rhodamine B appended ROMP derived fluorescent probe detects Al3+ and selectively labels lysosomes in live cells
errSCIENTIFIC REPORTS
IF3.9
err2020-11-11
err20
errOAAI
errGandra, Upendar Reddy; Courjaret, Raphael; Machaca, Khaled; Al-Hashimi, Mohammed; Bazzi, Hassan S.
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errSave
L-type Ca2+ channel blockers promote vascular remodeling through activation of STIM proteins
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2020-07-08
err43
errOAAI
errJohnson, Martin T.; Gudlur, Aparna; Zhang, Xuexin; Xin, Ping; Emrich, Scott M.; Yoast, Ryan E.; Courjaret, Raphael; Nwokonko, Robert M.; Li, Wei; Hempel, Nadine; Machaca, Khaled; Gill, Donald L.; Hogan, Patrick G.; Trebak, Mohamed
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errSave
Ca2+ signaling and lipid transfer 'pas a deux' at ER-PM contact sites orchestrate cell migration
errCELL CALCIUM
IF4
err2020-07-01
err9
errOAAI
errMachaca, Khaled
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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